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Presidents, Prime Ministers and Majorities in the French Fifth Republic
| Presidents, Prime Ministers and Majorities in the French Fifth Republic |
| Autore | Mişcoiu Sergiu |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing AG, , 2024 |
| Descrizione fisica | 1 online resource (223 pages) |
| Altri autori (Persone) | GuigoPierre-Emmanuel |
| Collana | Palgrave Studies in Presidential Politics Series |
| ISBN | 3-031-44664-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Contents -- Editors and Contributors -- About the Editors -- Contributors -- Presidents, Prime Ministers and Majorities in the French Fifth Republic -- References -- Charles de Gaulle: The Birth of the Modern French Monarchy, the Fifth Republic -- The End of the French Fourth Republic -- The Return to Power of General de Gaulle -- The Drafting and Adoption of a New Constitution -- The Birth of the Fifth Republic -- Creating New Institutions -- The Legislative and Presidential Elections of November-December 1958, the Second Unction of the Fifth Republic -- International Unrest Shaping the New Regime -- Settling the Algerian Conflict -- The Failure of the 'French Commonwealth' and the Creation of Franco-African Cooperation Agreements -- The Strengthening of the Fifth Republic by the de Gaulle Presidency (1962-1967) -- 1962, a Turning Point in the History of the Gaullist Republic -- The 1965 Presidential Election -- The Main Contributions of the Pompidou Governments -- The End of the de Gaulle Presidency (1968-1969) -- The Crisis of 1968 -- The Gaullist Swan Song: The Couve de Murville Government and the April 1969 Referendum -- De Gaulle and the Primacy of the Executive -- Conclusion -- References -- Georges Pompidou: Rooting the Fifth Republic -- Meritocracy and via crucis -- The "Dauphin" -- A "Bastard System" -- Peace with Parliament -- A Bipolar Political System -- The Two-Headed Eagle -- From Seven to Five -- The Élysée Palace -- The Prince's Seal -- The King's Two Bodies -- Conclusions -- References -- Valéry Giscard d'Estaing: "France Shall Not Fall Back into the Party Regime" -- A Man of the Institutions, a Well-Rooted Notable and, Occasionally, a Party Militant -- Intra-Executive Conflicts: Competitive Views on the Presidency or Power Politics.
Presidents Against Parties: When the Presidential Party Is too Small for Significant Reforms -- Conclusions -- References -- François Mitterrand: The Last Republican Monarch -- The Socialists' Adjustment to the Semi-presidential Regime (1981-1986) -- The First Cohabitation: A Rivalry Between the Prime Minister and the President (1986-1988) -- A More Parliamentarian Fifth Republic? (1988-1993) -- A President Weakened by Scandals and a New Cohabitation -- Conclusions -- References -- Jacques Chirac: The Failure of Social Gaullism, the Longest Cohabitation and the Spectre of the Far Right -- An All-Mighty President? -- The Longest Cohabitation: The End of the "Republican Monarchy"? -- The Chirac Quinquennium: The Return to Presidential Pre-eminence? -- A Loyal Prime Minister, Jean-Pierre Raffarin and a Strong Majority in Parliament -- Jacques Chirac Facing the Presidential Ambitions of Nicolas Sarkozy and Dominique de Villepin -- Conclusions -- References -- Nicolas Sarkozy: Voluntarism, Hyper-Presidency and Contestation -- Plus ça change, plus c'est la même chose: The French Polity under Change -- The Best of Frenemies: The Key Role of the Prime Minister in the Hyper-Presidency -- Restoring the Powers of Parliament and the Advent of the "Fifth Republic Bis" -- Conclusions -- References -- François Hollande: The Presidency at an Impasse -- The "Normal" President -- The Rapidly Weakened President -- A President Facing the Most Important Terrorist Attacks in French History -- An Impossible New Candidature -- Conclusion -- References -- Emmanuel Macron: The Art of Casting -- Real Power Lies in the Ability to Appoint -- Betting on an Open Casting Call -- Monitor and Punish -- Assemblies Subdued by the Executive? -- The Weakness of Neophytes -- The Strength of Institutions -- Conclusion -- References -- Index. |
| Record Nr. | UNINA-9910845493703321 |
Mişcoiu Sergiu
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| Cham : , : Springer International Publishing AG, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Preventive Cardiovascular Nursing : Resilience Across the Lifespan for Optimal Cardiovascular Wellness
| Preventive Cardiovascular Nursing : Resilience Across the Lifespan for Optimal Cardiovascular Wellness |
| Autore | Dunbar Sandra B |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing AG, , 2024 |
| Descrizione fisica | 1 online resource (738 pages) |
| Altri autori (Persone) | BraunLynne T |
| ISBN |
9783031537059
9783031537042 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Acknowledgments -- Contents -- Editors and Contributors -- Editors -- Contributors -- Part I: Foundations for Cardiovascular Disease Prevention -- 1: Introduction and Prevention Framework -- 1.1 Introduction: Making the Case for Cardiovascular Disease (CVD) Prevention -- 1.1.1 Disparities and Inequities in CVD -- 1.1.2 Prevalence of Risk Factors -- 1.1.3 Societal Burden of CVD -- 1.2 Goal of High-Level Wellness and Ideal Cardiovascular Health -- 1.3 Is Prevention of CVD Possible? -- 1.4 Traditional and Contemporary Perspectives on Risk: Biological, Psychological, Social, Behavioral, and Environmental -- 1.5 Levels of Prevention for CVD -- 1.6 Goal of Optimizing Resilience -- 1.7 Integrated Model of Ideal CV Health Promotion and Model of Nursing Interventions and Roles in Promoting Resilience to Optimize Ideal CVH -- 1.8 Summary -- References -- 2: Social Determinants of Cardiovascular Health -- 2.1 Introduction -- 2.1.1 Definition of Social Determinants of Health (SDoH) -- 2.1.2 Levels of Social Determinants -- 2.1.3 Socioeconomic Position -- 2.2 Individual-Level Determinants -- 2.2.1 Material Circumstances -- 2.2.2 Education -- 2.2.3 Income Inequality -- 2.2.4 Employment and Occupation -- 2.2.5 Psychological Factors -- 2.2.6 Behavioral Factors -- 2.2.7 Biological Factors -- 2.2.8 Neighborhood and Built Environment -- Neighborhood Crime and Violence -- Housing Instability, Quality, and Safety -- 2.2.9 Food Insecurity and Access -- 2.3 Structural/System-Level Determinants -- 2.3.1 Governance -- Jim Crow Laws, Residential Segregation, and Redlining -- 2.3.2 Macroeconomic, Social, and Public Policies -- Health-Care Policies and Health Systems -- Economic, Educational, and Infrastructural Deprivation -- 2.3.3 Culture and Societal Values: Social Cohesion and Social Capital.
2.4 Assessment of Social Determinants -- 2.4.1 Neighborhood-Level Measures of SDoH -- 2.5 Epidemiological Evidence on the Association Between Social Determinants and Cardiovascular Health -- 2.5.1 Race/Ethnicity, Racism, and Cardiovascular Health -- 2.5.2 Lifestyle Behaviors and Cardiovascular Health -- Diet -- Sleep -- Physical Activity -- Medication Adherence -- Tobacco Use -- 2.6 Interventions to Mitigate the Impact of Social Determinants on Cardiovascular Health -- 2.6.1 Larger-Scale Approaches: Governmental, Programmatic, and Community-Based -- Health Services Connections: Community Health Workers -- Nutrition and Food Access -- 2.6.2 Individual-Level Approaches -- 2.7 Conclusions -- References -- 3: Biological Pathways of Risk -- 3.1 Introduction -- 3.2 Molecular Pathways of Cardiovascular Risk -- 3.2.1 Genetics -- Genetic Polymorphisms -- Genome-Wide Association Studies (GWASs) -- 3.2.2 Epigenetics -- 3.2.3 Summary of Molecular Pathways -- 3.3 Inflammatory Pathways of Cardiovascular Risk -- 3.3.1 Atherosclerosis and Coronary Artery Disease -- Pathophysiology of Atherosclerosis -- Acute Coronary Syndrome -- 3.3.2 Hypertension -- 3.3.3 Heart Failure -- Innate Immunity -- Adaptive Immunity -- Peripheral Sources of Inflammation -- 3.3.4 Arrythmias -- 3.3.5 Modifiable Inflammatory CVD Risk Factors -- Smoking -- Physical Inactivity -- Diet -- Pharmacological Modulation of Inflammation in CVD Risk -- 3.3.6 Summary of Inflammatory Pathways -- 3.4 Neurohormonal Pathways of Cardiovascular Risk -- 3.4.1 Sympathetic Nervous System -- Renin-Angiotensin-Aldosterone System -- Role of RAAS in Atherosclerosis -- Role of RAAS in Hypertension -- Role of RAAS in Heart Failure -- Role of RAAS in Arrythmias -- 3.4.2 Stress Pathways -- 3.5 Metabolic Pathways of Cardiovascular Risk -- 3.5.1 Insulin Resistance -- Endothelial Dysfunction. Hypertension -- Dyslipidemia -- 3.5.2 Adiposity -- Inflammation -- Adipokines -- Obesity -- 3.5.3 Metabolic Abnormalities -- 3.5.4 Summary of Metabolic Risk -- 3.6 Conclusions -- References -- Part II: The Spectrum of Cardiovascular Risk -- 4: Risk Factors for Atherosclerotic Cardiovascular Disease -- 4.1 Introduction -- 4.2 Non-Modifiable Risk Factors -- 4.2.1 Age -- 4.2.2 Sex -- 4.2.3 Family History -- 4.2.4 Race and Ethnicity -- 4.3 Genetics and Epigenetics -- 4.3.1 Genetic Associations with CHD -- 4.3.2 Epigenetics -- 4.4 Modifiable Risk Factors -- 4.4.1 Dyslipidemia -- Relationship Between Hypercholesterolemia and CHD -- Clinical Practice Guidelines -- Primary and Secondary Prevention Statin Trials -- LDL Cholesterol Measurement -- Lipoproteins, Particle Number, and LDL Cholesterol -- HDL Particles -- Hypertriglyceridemia -- Elevated Lipoprotein (a) -- 4.5 Hypertension -- 4.5.1 Introduction -- 4.5.2 Blood Pressure Classification and Measurement -- 4.5.3 Risks Associated with SBP and DBP Elevation -- 4.5.4 Blood Pressure-Lowering Clinical Trials and CVD and Stroke Risk -- 4.5.5 Risk Factors for Hypertension: Genetics, Race, Dietary Factors, Alcohol, Obesity, and Physical Inactivity -- 4.6 Diabetes -- 4.6.1 Link Between Diabetes and CVD -- 4.6.2 CVD and Psychosocial Factors in Persons with Diabetes -- 4.6.3 Sex Differences -- 4.7 Metabolic Syndrome -- 4.7.1 Cardiometabolic Health in the U.S. -- 4.7.2 Research Supporting the Link Between MetS and CVD -- 4.8 Adverse Pregnancy Outcomes -- 4.9 Chronic Kidney Disease -- 4.10 Summary -- References -- 5: Behavior and Lifestyle Risk Factors -- 5.1 Definition of Behavioral and Lifestyle Risk Factors -- 5.2 Sedentary Behavior and Inactivity -- 5.3 Physical Activity -- 5.4 Dietary Patterns and Nutrition -- 5.5 Smoking and Tobacco Exposure -- 5.5.1 E-Cigarettes. 5.5.2 Heated Tobacco -- 5.5.3 Smokeless Tobacco Products -- 5.5.4 Second-Hand Smoke -- 5.6 Sleep -- 5.7 Stress -- 5.8 Alcohol and Substance Use -- 5.8.1 Substance Use Disorders -- Alcohol -- Other Substances -- Cannabis -- Opioids -- Amphetamines -- 5.9 Summary -- References -- 6: Psychosocial Risk Factors -- 6.1 Introduction -- 6.2 Allostatic Load -- 6.2.1 Relevance to Stress, Mental Illness, and CVD -- 6.3 Social Risk Factors -- 6.3.1 Adverse Childhood Experiences -- 6.3.2 Economic Stress and Low Socioeconomic Status -- Food Insecurity -- Housing Instability -- Education Level -- Limited Access to Resources to Manage Stressors -- 6.3.3 Access to Adequate Healthcare -- 6.3.4 Employment Stressors -- 6.3.5 Community Factors -- 6.3.6 Racism -- 6.3.7 Intimate Partner Violence -- 6.3.8 Incarceration -- 6.4 Mental Health Risk Factors -- 6.4.1 Depression -- Pathophysiological Implications -- Medication -- Associated Psychosocial Risk Factors -- 6.4.2 Anxiety Disorders -- Pathophysiological Implications -- Medication -- Associated Psychosocial Risk Factors -- 6.4.3 Post-traumatic Stress Disorder -- Pathophysiological Implications and Associated Psychosocial Risk Factors -- Medication -- 6.4.4 Schizophrenia and Other Psychotic Disorders -- Associated Psychosocial Risk Factors -- Medication -- 6.4.5 Bipolar Disorder -- Associated Psychosocial Risk Factors -- Medication -- 6.4.6 Substance Use Disorders -- 6.4.7 Attention-Deficit/Hyperactivity Disorder -- Medication -- 6.4.8 Sleep Disorders -- Medications -- 6.5 Conclusion -- References -- 7: Chronic and Other Conditions That Increase CVD Risk -- 7.1 Risk-Enhancing Conditions -- 7.2 Obesity -- 7.2.1 Introduction and Definition -- 7.2.2 Prevalence -- 7.2.3 Social Determinants of Health -- Economic Stability and Food Access. Neighborhood, Built Environment, and Social and Community Context -- Quality and Education Access and Quality and Home Care Access -- 7.2.4 Genetics -- 7.2.5 Obesity Paradox -- 7.2.6 Diagnosis -- 7.2.7 Treatment and Treatment Goals -- 7.2.8 Prevention -- 7.3 Rheumatic Diseases and Cardiovascular Disease Risks -- 7.3.1 Introduction -- 7.3.2 Rheumatic Diseases -- Definition, Diagnosis, and Guidelines -- Epidemiology -- Signs and Symptoms -- Etiology, Pathogenesis, and Risk Factors -- Clinical Treatment and Management -- Health Outcomes -- Comorbidities -- 7.3.3 Rheumatic Diseases and Cardiovascular Disease Risk -- Epidemiology -- Cardiovascular Signs, Symptoms, and Diseases in Rheumatic Diseases -- Risk Factors, Etiology, and Pathogenesis -- Prevention and Management -- 7.3.4 Summary -- 7.4 HIV and Cardiovascular Disease Risk -- 7.4.1 Overview and Epidemiology -- 7.4.2 Multifactorial Pathogenesis for CVD -- Chronic Inflammation and Immune Activation -- Metabolic Risk Factors -- Antiretroviral Drugs and CVD -- 7.4.3 Traditional Risk Factors -- 7.4.4 Risk Assessment -- 7.4.5 Disparities in CVD Care -- Reducing Disparities -- 7.4.6 CVD Risk Reduction Strategies -- Physical Activity -- Weight Management and Dietary Interventions -- Smoking Cessation -- Substance Disorders -- 7.4.7 HIV and CVD Risk Conclusions and Future Directions -- 7.5 HIV Case Study -- 7.6 Spontaneous Coronary Artery Dissection -- 7.6.1 Prevalence -- 7.6.2 Pregnancy-Associated SCAD -- 7.6.3 Symptoms and Clinical Presentation -- 7.6.4 Pathophysiology of SCAD -- 7.6.5 Diagnosis -- 7.6.6 Management -- 7.6.7 Prevention/Recurrence -- Follow-Up and Patient Counseling -- 7.6.8 Pregnancy After SCAD -- 7.6.9 Summary -- 7.7 Chapter Summary -- References -- Risk Enhancing Conditions -- Obesity -- Rheumatic Diseases and Cardiovascular Disease Risks. HIV and Cardiovascular Disease Risk. |
| Record Nr. | UNINA-9910865292803321 |
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Dunbar Sandra B
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| Cham : , : Springer International Publishing AG, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Primary Adrenal Malignancies
| Primary Adrenal Malignancies |
| Autore | Tiberio Guido A. M |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing AG, , 2024 |
| Descrizione fisica | 1 online resource (177 pages) |
| Altri autori (Persone) | Tiberio |
| Collana | Updates in Surgery Series |
| ISBN | 3-031-62301-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Foreword -- Preface -- Contents -- 1: Epidemiology, Presentation, Staging, and Prognostic Factors in Adrenocortical Carcinoma -- 1.1 Epidemiology -- 1.2 Clinical Presentation -- 1.3 Staging and Risk Assessment -- References -- 2: Epidemiology, Presentation, Staging, and Prognostic Factors in Malignant Pheochromocytoma -- 2.1 Introduction -- 2.2 Presentation -- 2.3 Biochemical Diagnosis -- 2.4 Perioperative Management -- 2.5 Staging -- 2.6 Prognostic Factors -- 2.7 Postoperative Follow-Up -- References -- 3: Genetics and Molecular Biology of Adrenocortical Carcinoma -- 3.1 Introduction -- 3.2 Germline DNA Mutations and the Hereditary Component of Adrenocortical Carcinoma -- 3.3 Chromosomal Number Alteration (Aneuploidy) -- 3.4 Somatic DNA Mutations and Tumor Mutation Burden -- 3.5 Epigenetic (Post-Translational) Changes -- 3.6 An Integrative View of Molecular Biology of Adrenocortical Carcinoma -- 3.7 Spatial/Temporal Molecular Heterogeneity in Adrenocortical Carcinoma -- References -- 4: Genetics and Molecular Biology of Pheochromocytoma and Paraganglioma -- 4.1 Introduction -- 4.2 NF1 Gene -- 4.3 RET Gene -- 4.4 VHL Gene -- 4.5 SDHx Genes and SDHAF2 Gene -- 4.5.1 SDHD Gene (PGL1 Syndrome) -- 4.5.2 SDHAF2 Gene (PGL2 Syndrome) -- 4.5.3 SDHC Gene (PGL3 Syndrome) -- 4.5.4 SDHB Gene (PGL4 Syndrome) -- 4.5.5 SDHA Gene (PGL5 Syndrome) -- 4.6 TMEM127 Gene -- 4.7 MAX Gene -- 4.8 FH Gene -- 4.9 Other Genes -- 4.10 Molecular Biology -- References -- 5: Imaging in Adrenocortical Carcinoma and Malignant Pheochromocytoma -- 5.1 Introduction -- 5.2 Washout CT of Adrenal Lesions -- 5.3 MRI of Adrenal Lesions -- 5.4 Adrenocortical Carcinoma -- 5.5 Malignant Pheochromocytoma -- 5.6 Nuclear Medicine and Pheochromocytoma -- 5.7 Comparison Between Nuclear Medicine Modalities -- 5.8 Conclusions -- References.
6: Management of Endocrine Syndromes Associated with Adrenocortical Carcinoma -- 6.1 How Often Will I Find an Adrenocortical Carcinoma with Associated Endocrine Syndromes in My Practice? -- 6.2 What Is the Clinical Presentation of Adrenocortical Carcinoma with Associated Endocrine Syndromes? -- 6.3 How to Diagnose the Endocrine Syndrome Associated with Adrenocortical Carcinoma? -- 6.4 Does Hypercortisolism Affect Patient Outcome? -- 6.5 Which Treatment for Endocrine Syndromes? -- References -- 7: Management of Hereditary Syndromes Associated with Pheochromocytoma/Paraganglioma -- 7.1 Introduction -- 7.2 Neurofibromatosis Type 1 -- 7.3 Multiple Endocrine Neoplasia 2 -- 7.4 Von Hippel Lindau Syndrome -- 7.5 SDHx-associated Hereditary PPGL -- 7.6 TMEM127- and MAX-associated PPGL -- 7.7 FH-associated PPGL -- References -- 8: Adrenal Incidentaloma -- 8.1 What Does "Adrenal Incidentaloma" Mean? -- 8.2 How Often Will I Find an Adrenal Incidentaloma in My Practice? -- 8.3 What Type of Adrenal Tumor Can Be Found Incidentally? -- 8.4 What Should I Do Next After Discovering an Adrenal Incidentaloma? -- 8.4.1 Risk of Malignancy -- 8.4.2 Hormonal Activity -- 8.5 Which Treatment? -- 8.6 Which Patients Deserve Particular Consideration? -- 8.6.1 Mild Autonomous Cortisol Secretion -- 8.6.2 Bilateral Adrenal Incidentalomas -- 8.6.3 Younger People (< -- 40 Years) -- References -- 9: Surgery for Adrenocortical Carcinoma -- 9.1 Introduction -- 9.2 Upfront Adrenalectomy: The Guidelines -- 9.2.1 The Literature -- 9.2.1.1 R.3.1 -- 9.2.1.2 R.3.2 and R.3.4 -- 9.2.1.3 R.3.7 -- 9.2.2 Reasoning to Establish a Sound Surgical Strategy -- 9.3 Surgery for Recurrent Disease: The Guidelines -- 9.3.1 The Literature -- 9.3.2 Reasoning to Establish a Sound Surgical Strategy -- References -- 10: Adrenocortical Carcinoma with Vena Cava Involvement. 10.1 The Guidelines -- 10.2 The Multidisciplinary Team -- 10.3 The Cancer and the Patient -- 10.4 Technical Aspects -- 10.5 Results -- 10.6 Final Considerations -- References -- 11: Adrenocortical Carcinoma: The Posterior Minimally Invasive Approach -- 11.1 Introduction -- 11.2 Surgical Technique -- 11.3 Discussion -- 11.4 Conclusions -- References -- 12: Surgery for Malignant Pheochromocytoma -- 12.1 The Guidelines -- 12.2 Indication for Surgery -- 12.3 Surgical Strategies and Techniques -- 12.4 Case Report -- References -- 13: Open or Laparoscopic Surgery in the Management of Adrenocortical Carcinoma? -- 13.1 Introduction -- 13.2 Studies in Favor of Minimally Invasive Adrenalectomy -- 13.3 Studies in Favor of Open Adrenalectomy -- 13.4 Discussion and Guideline Recommendations -- References -- 14: Pathology of Adrenocortical Carcinoma and Malignant Pheochromocytoma -- 14.1 Introduction -- 14.2 Adrenocortical Carcinoma -- 14.2.1 Gross Pathology -- 14.2.2 Cytological and Histological Findings -- 14.2.3 Scoring Systems -- 14.2.4 Histological Subtypes -- 14.2.5 Pediatric Adrenocortical Tumors -- 14.2.6 Grading -- 14.2.7 Staging -- 14.2.8 Immunohistochemical Profile -- 14.3 Malignant Pheochromocytoma -- 14.3.1 Gross Pathology -- 14.3.2 Cytological and Histological Findings -- 14.3.3 Pathological Prediction of a Clinically Aggressive Course -- 14.3.4 Staging -- 14.3.5 Immunohistochemical Profile -- References -- 15: Medical Treatment in Advanced Adrenocortical Carcinoma -- 15.1 Introduction -- 15.2 Standard Systemic Therapy: Mitotane -- 15.3 Combination Therapy: Chemotherapy plus Mitotane (EDP-M) -- 15.4 Beyond EDP-M -- References -- 16: Integrated Approach in Locally Advanced, Oligometastatic or Recurrent Adrenocortical Carcinoma -- 16.1 Introduction -- 16.2 Neoadjuvant Chemotherapy Followed by Surgery. 16.3 Adrenalectomy: Upfront or After Primary Chemotherapy in the Metastatic Setting? -- 16.4 Cytoreduction and Hyperthermic Intra-peritoneal Chemotherapy -- 16.4.1 Alternative Locoregional Treatments -- References -- 17: Medical Treatment of Malignant Pheochromocytoma -- 17.1 Chemotherapy -- 17.2 Targeted Therapy -- 17.3 Immunotherapy -- References -- 18: Role of Radiotherapy in Adrenocortical Carcinoma and Pheochromocytoma -- 18.1 Role of Radiotherapy in Adrenocortical Carcinoma -- 18.1.1 Radiobiology of Adrenocortical Carcinoma -- 18.1.2 Adjuvant Radiotherapy -- 18.1.2.1 Aim of Radiotherapy -- 18.1.2.2 Patient Selection -- 18.1.2.3 Efficacy and Timing -- 18.1.2.4 Acute and Late Toxicity -- 18.1.2.5 Radiotherapy Technique, Dose and Volumes -- 18.1.2.6 Concurrent Systemic Therapy to Radiotherapy -- 18.1.3 Definitive Radiotherapy for Unresectable Disease or Local Recurrence -- 18.1.4 Radiotherapy for Metastatic Disease and Palliation -- 18.2 Role of Radiotherapy in Pheochromocytoma -- 18.2.1 Radiobiology of Pheochromocytoma -- 18.2.2 Radiotherapy for Metastatic Disease and Palliation -- 18.2.3 Adjuvant Radiotherapy and Definitive Radiotherapy (Unresectable Disease) -- References -- 19: Radionuclide Treatment in Malignant Pheochromocytoma -- 19.1 Introduction -- 19.2 131I-MIBG Therapy -- 19.2.1 HSA 131I-MIBG -- 19.2.2 LSA 131I-MIBG -- 19.2.3 Contraindications and Adverse Effects -- 19.3 Peptide Receptor Radionuclide Therapy -- 19.3.1 90Y- and 177Lu-Labeled DOTA Compounds -- 19.3.2 Contraindications and Adverse Effects -- 19.4 Comparison Between 131I-MIBG Therapy and Peptide Receptor Radionuclide Therapy -- References -- 20: Preclinic and Translational Research in Adrenal Malignancies -- 20.1 Introduction -- 20.2 Adrenocortical Carcinoma: Preclinical and Translational Models -- 20.2.1 Cell Lines -- 20.2.2 3D Cell Models. 20.2.3 Cell Xenograft in Mouse -- 20.2.4 Genetically Engineered Mouse Models -- 20.3 Pheochromocytoma/Paraganglioma Preclinical and Translational Models -- 20.3.1 Cell Lines -- 20.3.2 Rat Pheochromocytoma (PC12) -- 20.3.3 Mouse Pheochromocytoma Cell Line and Mouse Tumor Tissue Cells -- 20.3.4 Immortalized Chromaffin Cells -- 20.3.5 Rat SDH-Deficient RS0 Cells -- 20.3.6 Progenitor Cells Derived from a Human Pheochromocytoma -- 20.3.7 Animal Models -- 20.4 Complex 3D Adrenal In Vitro Preclinical Models -- References. |
| Record Nr. | UNINA-9910878790003321 |
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Tiberio Guido A. M
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| Cham : , : Springer International Publishing AG, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Primary and Secondary Education During Covid-19 : Disruptions to Educational Opportunity During a Pandemic
| Primary and Secondary Education During Covid-19 : Disruptions to Educational Opportunity During a Pandemic |
| Autore | Reimers Fernando M |
| Pubbl/distr/stampa | Cham, : Springer International Publishing AG, 2021 |
| Descrizione fisica | 1 online resource (467 p.) |
| Soggetto topico |
Education
Educational strategies & policy Study & learning skills: general Organization & management of education Ensenyament a distància Telecomunicació en l'ensenyament Política educativa Pandèmia de COVID-19, 2020- |
| Soggetto genere / forma | Llibres electrònics |
| Soggetto non controllato |
Open Access
Education and Covid-19 Educational Inequality Education Disruption Education Policy Education Technology Comparative Education Remote learning Schooling during a pandemic Distance teaching post-pandemic educational policies Homeschooling during Pendemic understanding Inequities in Instruction and Learning Education in the times of Covid-19 Unequal Impacts of COVID-19 |
| ISBN | 3-030-81500-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Contents -- 1 Learning from a Pandemic. The Impact of COVID-19 on Education Around the World -- 1.1 Introduction -- 1.2 Goals and Significance of this Study -- 1.3 A Stylized Global Summary of the Facts -- 1.4 The Backdrop to the Pandemic: Enormous and Growing Inequality and Social Exclusion -- 1.5 The Pandemic and Health -- 1.6 The Pandemic, Poverty, and Inequality -- 1.7 Readiness for Remote Teaching During a Pandemic -- 1.8 What are the Short-term Educational Impacts of the Pandemic? -- 1.9 Methods -- References
2 Experiences with Risk-Management and Remote Learning During the COVID-19 Pandemic in Brazil: Crises, Destitutions, and (Possible) Resolutions -- 2.1 Introduction -- 2.2 Education and Its Discontents with COVID-19 in Brazil: When the Wave of Uncertainty Hits the Hardest, Risk-Management Needs to Be in Place -- 2.3 The Loss of Instructional Time and the Sense of Urgency to Mitigate COVID-19 Shocks -- 2.4 New Means of Instruction and Curriculum Reprioritization in the COVID-19 Context -- 2.5 The Variance of Responses Against COVID-19 and the Waning of Learning and Participation 2.6 The Attempt to Gradually Reopen Schools to Avoid Further Losses: The Contentious Site of Education -- 2.7 Planting Seeds of Hope in Shaken Terrain: The Possibilities to Build a Future After a Traumatic Event -- Appendix -- References -- 3 The Fragility of the School-in-Pandemic in Chile -- 3.1 Education in Chile: Basic Context -- 3.2 Policies Adopted to Confront the Pandemic in Education -- 3.3 Effects of the Pandemic on the Educational Process and the Responses of Actors -- 3.4 The Fragility of the Experience of Schooling at Home -- 3.5 Final Reflections: Looking to the Post-pandemic School Appendix 1 -- References -- 4 Experiences of Moving Quickly to Distance Teaching and Learning at All Levels of Education in Finland -- 4.1 Introduction -- 4.2 Finnish Education Context -- 4.3 Preconditions for Distance Teaching and Learning During the Pandemic -- 4.4 Organisation of Teaching and Learning During the Pandemic -- 4.5 School-Level Teaching and Learning Experiences During the Pandemic -- 4.6 Teacher, Principal and Student Well-Being During the Pandemic -- 4.7 Discussion -- References 5 Covid-19 and Education on the Front Lines in Japan: What Caused Learning Disparities and How Did the Government and Schools Take Initiative? -- 5.1 Introduction -- 5.2 The COVID-19 Pandemic and Japan's Response -- 5.3 Home-Based Learning During the School Closure and MEXT's Policy Initiatives -- 5.3.1 Background: Japan's Education System -- 5.3.2 Disparity in Home-Based Learning During School Closure by School Type -- 5.3.3 Disparity in Home-Based Learning During School Closure by Prefecture -- 5.3.4 The GIGA School Initiative as the Policy Solution 5.3.5 MEXT's Additional Supportive Policy Measures |
| Record Nr. | UNINA-9910500587103321 |
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Reimers Fernando M
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| Cham, : Springer International Publishing AG, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Primary Physical Science Education : An Imaginative Approach to Encounters with Nature
| Primary Physical Science Education : An Imaginative Approach to Encounters with Nature |
| Autore | Fuchs Hans U |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing AG, , 2023 |
| Descrizione fisica | 1 online resource (356 pages) |
| Altri autori (Persone) | CorniFederico |
| ISBN | 3-031-43953-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Notes and Materials -- Acknowledgements -- Attributions for figures -- Contents -- Chapter 1 Myth, Imagination, and Science -- 1.1 Experience, Myth, and Imagination -- Wind in ancient cultures -- Why We Need Wind -- Wind as a Force of Nature (FoN) -- Myth -- Experiencing and communicating about Forces of Nature -- 1.2 The Development of Myth and Orality -- Before myth: Episodic and mimetic cultures -- Mythic Culture and Oral Language -- Mythic art: Abstraction and imagination -- Orality and Literacy: Development of writing -- 1.3 Children's Oral Mythic World -- Cultural evolution & -- Cultural Recapitulation -- Children and the power of abstraction and imagination -- Cognitive tools of mythic understanding -- Pattern, polarity, metaphor, and story -- 1.4 Taking Steps Towards Physical Science -- What makes science different from myth? -- Tools of literacy in emerging science and theoretic understanding -- A sense of reality „Out There," romantic realism, and theoretic culture -- Pedagogy of early science education -- A „modern" story of a storm -- 1.5 PPSE and Physical Science -- Debating the meaning of Physics and Force -- The scientific category of Forces of Nature -- PPSE-An imaginative scientific approach to Forces -- Notes -- Chapter 2 Encounters with Forces of Nature -- 2.1 Experiencing Forces -- 2.2 Polarities-Tensions Create Forces -- Experiencing polarities and tensions -- Forces associated with polarities and felt tensions -- Experiencing polarities and communicating about them -- 2.3 Wind, Rain, Fire, and Light -- How we experience Wind -- Getting to know Rain -- Chains of processes -- The abstract meaning of Force of Nature (FoN) -- Fire as a powerful agent -- Light as a Force of Nature -- Thunderstorms: Lightning and thunder -- 2.4 Rain and Water, Wind and Air -- New polarities and extensions for Water and Air.
Water as a Hydraulic Force of Nature -- Wind and Air -- Light-as-Substance -- Lightning as electrical -- 2.5 Shifting Our Perspective -- Activities as bringers or producers of „stuff" -- New polarities, new Forces. . . -- 2.6 Invisible Fluids as Forces-The Case of Cold -- Snow, Ice, and Cold -- And then there are still more invisible agents. . . -- Notes -- Chapter 3 Wind, Water, and Gravity -- 3.1 Letting Wind and Water Interact -- Pumping Water with Wind -- Power explains relation of Forces in interactions -- 3.2 Quantifying Aspects of Wind and Water -- Extension of wind -- Quantifying the intensity of wind -- Wind as flowing air -- Intensity of Fluid in hydraulic phenomena -- Storage and flow of water-The concept of amount of fluid -- Amount and flow of fluids, and hydraulic tension -- 3.3 Water and Gravity Interacting -- Experiencing things as heavy or light -- Experiencing gravity -- A measure of amount of Gravity -- Intensity and tension of Gravity -- The gravitational field -- 3.4 Fluids „Stacked" in the Gravitational Field -- Letting the Forces of Gravity and Fluid interact -- Columns of liquids for measuring pressure -- Pressure of air in our atmosphere -- Pressure is a level-metaphorically speaking -- 3.5 Fluid Flow and Hydraulic Tension -- The relation between tension and flow -- Embodied Simulations-Feeling and understanding tension and flow -- 3.6 The Power of a Waterfall -- Constructing a formal expression for the power of Gravity -- Rising flames and balloons -- 3.7 The Role of Energy in Physical Processes -- An analogy for the relation between energy and power -- Energy made available, transferred, and stored -- Accounting for amounts of energy -- 3.8 Experiencing Fluids Creates Schemas -- Notes -- Chapter 4 Heat as a Force of Nature -- 4.1 Experiencing Hotness and Heat -- The sensation of warm and cold. The scale of hotness and the construction of temperature -- Imaginative experience of a fluidlike Quantity of Heat -- Embodied Simulation of thermal tension -- 4.2 Storing Heat, Letting It Flow, and Producing It -- An experiment suggesting the concept of amount of heat -- Heat flowing through materials -- A flow-tension relation for conduction of heat -- Two more ways of transporting heat -- Pumping heat -- Heat can be produced, but not destroyed -- Quantity of heat in imagination -- 4.3 Ice, Water, and Steam-The Role of Heat -- Ice, water, and heat -- Water, steam, and heat -- Boiling and freezing points -- Humid air -- Steam responding to heat -- 4.4 The Motive Power of Fire -- A very brief history of heat engines -- Carnot's suggestion for how to express the Power of Heat -- Heat and Water interacting in heat driven water pumps -- Heat pumps pump heat -- Power of the process that produces heat -- 4.5 Power and Efficiency of Thermal Processes -- The idea of efficiency of an interaction -- Conduction of heat-heat diffusing through materials -- The main limiting factor of the efficiency of heat engines -- Why we should pump rather than produce heat -- Measuring amounts of heat -- 4.6 Winds, Volcanoes, and Continental Drift -- Sun and Earth: Sizes and distance -- How much sunlight is there? -- Heat created when sunlight is absorbed -- Heat from the interior of the Earth -- Gently heating fluid layers from below: Observing convection -- How heat created by the Sun's light drives the „wind engine" -- The wind engine, in greater detail -- How How Heat from the Earth drives plate tectonics and volcanism -- Notes -- Chapter 5 Imagining Forces - Towards Visual Storytelling -- 5.1 The The Perpetuum Mobile Story -- 5.2 Forces of Nature in the Perpetuum Mobile Animation -- Matter (or physical objects) and energy -- Figure-Ground Reversal. Properties and activities of spirits -- Producing heat-the role of irreversibility -- 5.3 Energy in the Perpetuum Mobile Animation -- Dust as visual metaphor for energy -- Properties of energy-suggested by properties of dust -- Why doesn't a perpetual motion machine work? -- Power-measuring the magnitude of ongoing causation -- Agents at work -- 5.4 Visual Metaphors for Fluid and Potential -- The schema of fluid substance -- Experiencing and visualizing potential -- 5.5 Visualizing Forces of Nature in Process Diagrams -- Visualizing the energy exchanged in interactions -- Transmitting and storing energy -- A list of visual schemas in process diagrams -- Examples of process diagrams -- Process diagrams for dynamical systems -- 5.6 Forces-of-Nature Theater as Embodied Simulation -- Couplers and paths -- Agents and patients, interactions, and energy -- Notes -- Chapter 6 Science for Children? -- 6.1 Engaging with Forces of Nature-A Summary -- 6.2 Learning About FoN-An Example of Primary Pedagogy -- Theme, context, and motivation -- An extended unit of primary nature pedagogy -- 6.3 Studying the „Technical" Background -- Wind interacting with Water -- Where does Wind come from? -- The origin of Rain -- 6.4 Designing Direct Physical Experience -- 6.5 Designing Stories of Forces of Nature -- 6.6 Designing and Using FoN Theater Performances -- 6.7 Where We Go from Here -- Notes -- Glossary -- References -- Index. |
| Record Nr. | UNINA-9910746981203321 |
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Fuchs Hans U
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| Cham : , : Springer International Publishing AG, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Principal investigators and R&D failure : probability of innovation failure in small businesses / / Morgan Boyce
| Principal investigators and R&D failure : probability of innovation failure in small businesses / / Morgan Boyce |
| Autore | Boyce Morgan |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing AG, , 2023 |
| Descrizione fisica | 1 online resource (xiii, 122 pages) : illustrations |
| Collana | Academic Entrepreneurship, Scientists, and Scientific Careers Series |
| Soggetto topico |
Business failures
Research and development projects Research, Industrial |
| ISBN |
9783031436086
9783031436079 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Acknowledgments -- Contents -- Chapter 1: Introduction -- Chapter 2: R& -- D Project Failure and Principal Investigators -- 2.1 R& -- D Project Failure -- 2.1.1 Defining Success and Failure -- 2.1.2 Measuring Business Failure -- Why Businesses Fail -- 2.2 Principal Investigators -- 2.2.1 Multifaceted Responsibilities -- 2.2.2 The Goal of Commercialization -- 2.3 Conclusion -- Part I: Contextual Setting -- Chapter 3: Publicly Funded Collaborative R& -- D: The Case of the US Department of Energy -- 3.1 Introduction -- 3.2 The Early History of DOE -- 3.3 DOE Is Formalized -- 3.4 Current Organization of the DOE and Support for PIs -- 3.5 Conclusion -- Chapter 4: Legislative History of the SBIR Program -- 4.1 Introduction -- 4.2 The SBIR Program -- 4.3 The Empirical Literature on the SBIR Program -- 4.4 SBIR and the Department of Energy -- 4.5 Conclusion -- Chapter 5: A Theoretical Model of R& -- D Project Success or Failure -- 5.1 Introduction -- 5.2 Revenue and Costs of a New Technology -- 5.3 Profit-Maximizing Choice of R& -- D Inputs -- Chapter 6: Department of Energy and SBIR Data -- 6.1 Background -- 6.2 Survey Data -- 6.3 Measures of Failure -- 6.4 Conclusion -- Chapter 7: Collaborative R& -- D Firm and Project Characteristics: Empirical Insights -- 7.1 Introduction -- 7.2 Initial Probit Model -- 7.2.1 Independent Variables Considered -- 7.2.2 Descriptive Statistics -- 7.2.3 Relationships Between Independent Variables and Failure -- 7.2.4 Relationships Between Independent Variables and TechFailure -- 7.3 Initial Probit Model Results -- 7.3.1 Set One Model Results -- 7.3.2 Set Two Model Results -- 7.3.3 Set Three Model Results -- 7.3.4 Variance Inflation Factors -- 7.4 Conclusion -- Chapter 8: Principal Investigators' Experience in Collaborative R& -- D: Empirical Findings -- 8.1 Introduction.
8.1.1 PI Hypothesized Relationships with Project Failure -- 8.2 PI Demographics -- 8.2.1 Descriptive Statistics -- 8.2.2 Model Results with PI Demographics -- 8.3 PIs as CEOs/Firm Founders -- 8.3.1 Descriptive Statistics -- 8.3.2 Model Results with PI as Firm Leaders -- 8.4 Homophilic Gender Composition -- 8.5 Conclusion -- Part II: Reflections and Future Perspectives -- Chapter 9: PIs and R& -- D Project Failure: Reflections and Future Research Avenues -- 9.1 Introduction -- 9.2 Discussion -- 9.2.1 DOE's SBIR Program -- 9.2.2 R& -- D Project Failure and the Role of PIs -- 9.2.3 Review of Empirical Results -- 9.3 Limitations -- 9.4 Implications for Policy and Practice -- 9.5 Future Research -- 9.6 Conclusion -- References -- Index. |
| Record Nr. | UNINA-9910754091003321 |
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Boyce Morgan
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| Cham : , : Springer International Publishing AG, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Principled Pragmatism in Mexico's Foreign Policy : Variables and Assumptions
| Principled Pragmatism in Mexico's Foreign Policy : Variables and Assumptions |
| Autore | Velazquez-Flores Rafael |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing AG, , 2022 |
| Descrizione fisica | 1 online resource (356 pages) |
| Collana | Global Foreign Policy Studies |
| ISBN | 3-030-99573-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910584483203321 |
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Velazquez-Flores Rafael
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| Cham : , : Springer International Publishing AG, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Principles and Applications of Tribology
| Principles and Applications of Tribology |
| Autore | Ajimotokan Habeeb Adewale |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing AG, , 2024 |
| Descrizione fisica | 1 online resource (83 pages) |
| Collana | SpringerBriefs in Applied Sciences and Technology Series |
| ISBN | 3-031-57409-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910847076203321 |
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Ajimotokan Habeeb Adewale
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| Cham : , : Springer International Publishing AG, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Principles and Pedagogies in Jewish Education
| Principles and Pedagogies in Jewish Education |
| Autore | Chazan Barry |
| Pubbl/distr/stampa | Cham, : Springer International Publishing AG, 2021 |
| Descrizione fisica | 1 online resource (103 p.) |
| Disciplina | 296.68 |
| Soggetto topico |
Philosophy & theory of education
Educational strategies & policy Child & developmental psychology Jueus Educació Educació religiosa |
| Soggetto genere / forma | Llibres electrònics |
| Soggetto non controllato |
Moral Education
Faith-based education experiential learning educational philosophy indoctrination Open Access |
| ISBN | 3-030-83925-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910504284503321 |
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Chazan Barry
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| Cham, : Springer International Publishing AG, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Principles and Praxis in Ancient Greek Philosophy : Essays in Ancient Greek Philosophy in Honor of Fred D. Miller, Jr
| Principles and Praxis in Ancient Greek Philosophy : Essays in Ancient Greek Philosophy in Honor of Fred D. Miller, Jr |
| Autore | Keyt David |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing AG, , 2024 |
| Descrizione fisica | 1 online resource (442 pages) |
| Altri autori (Persone) | ShieldsChristopher |
| Collana | Philosophical Studies Series |
| ISBN | 3-031-51146-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910845083503321 |
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Keyt David
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| Cham : , : Springer International Publishing AG, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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