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Leukodystrophies [[electronic resource] /] / edited by Gerald V. Raymond ... [et al.]
Leukodystrophies [[electronic resource] /] / edited by Gerald V. Raymond ... [et al.]
Pubbl/distr/stampa London, : Mac Keith Press, 2011
Descrizione fisica 1 online resource (249 p.)
Disciplina 618.928
Altri autori (Persone) RaymondGerald V
Collana International review of child neurology series
Soggetto topico Leukodystrophy, Metachromatic
ISBN 1-907655-41-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""CONTENTS""; ""AUTHORS� APPOINTMENTS""; ""FOREWORD""; ""1 LEUKODYSTROPHY AND MYELIN""; ""Introduction""; ""Definition of leukodystrophies""; ""2 MYELINATION IN HEALTH AND DISEASE""; ""Introduction""; ""Oligodendrocytes have a highly polarized shape""; ""Molecular composition of myelin and oligodendrocyte membranes""; ""Molecular mechanisms of myelin membrane formation""; ""Reciprocal interactions between axons and oligodendrocytes""; ""Summary and conclusions""; ""3 THE ROLE OF ASTROCYTES IN WHITE MATTER DISEASE""; ""Introduction""; ""Cellular lineage systems in the mammalian brain""
""Astrocytes in development and adult life""""Leukodystrophies with distinct astrocyte pathology""; ""Possible mechanisms of white matter damage secondary to astrocyte dysfunction""; ""Summary and future perspectives""; ""4 MICROGLIA AND LEUKODYSTROPHIES""; ""Introduction""; ""Macrophage populations in the central nervous system""; ""Defining microglial activation""; ""Microglia in development and repair""; ""Brain colonization, self-renewal, and post-lesional recruitment of microglia""; ""Microglia in the pathogenesis of leukodystrophies""; ""Adrenoleukodystrophy""
""Does VLCFA accumulation cause microglial activation?""""How does microglial activation relate to demyelination in adrenoleukodystrophy?""; ""Metachromatic leukodystrophy""; ""Microglia in globoid cell leukodystrophy (Krabbe disease)""; ""The role of microglia in transplantation""; ""Concluding remarks""; ""5 X-LINKED ADRENOLEUKODYSTROPHY""; ""Introduction""; ""Biochemical and molecular basis""; ""Clinical features""; ""Diagnosis""; ""Animal models""; ""Pathogenesis""; ""Therapy in adrenoleukodystrophy""; ""Expanded screening for asymptomatic individuals""
""6 KRABBE DISEASE (GLOBOID CELL LEUKODYSTROPHY)""""Introduction""; ""Clinical features""; ""Diagnostic evaluation""; ""Pathological findings""; ""Biochemical findings""; ""Molecular genetics""; ""Newborn screening""; ""Studies in animal models""; ""Therapy""; ""Conclusions""; ""7 ALEXANDER DISEASE""; ""Introduction""; ""Clinical presentation""; ""MRI characteristics""; ""Pathology""; ""Diagnosis""; ""GFAP mutations""; ""Cases without GFAP mutations""; ""Recent cases""; ""Disease mechanisms""; ""Treatment""; ""Concluding remarks""; ""8 METACHROMATIC LEUKODYSTROPHY""
""Classification and definition""""Incidence and prevalence""; ""Genetics""; ""Biochemical background""; ""Pathophysiology""; ""Clinical features""; ""Laboratory and genetic diagnosis""; ""Therapy""; ""9 CANAVAN DISEASE""; ""Introduction""; ""Molecular basis""; ""Clinical features""; ""Variant forms of the disease""; ""Differential diagnosis""; ""Pathogenesis and pathophysiology""; ""Prognosis""; ""Epidemiology""; ""Gene therapy""; ""Prevention""; ""10 PELIZAEUS�MERZBACHER DISEASE: GENETIC MODELS AND MECHANISMS""; ""Involvement of myelin proteolipid protein""; ""The PLP1 gene""
""Genetics of PMD/SPG-2""
Record Nr. UNINA-9910779149903321
London, : Mac Keith Press, 2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Leukodystrophies / / edited by Gerald V. Raymond ... [et al.]
Leukodystrophies / / edited by Gerald V. Raymond ... [et al.]
Edizione [1st ed.]
Pubbl/distr/stampa London, : Mac Keith Press, 2011
Descrizione fisica 1 online resource (249 p.)
Disciplina 618.928
Altri autori (Persone) RaymondGerald V
Collana International review of child neurology series
Soggetto topico Metachromatic leukodystrophy
ISBN 1-907655-41-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""CONTENTS""; ""AUTHORS� APPOINTMENTS""; ""FOREWORD""; ""1 LEUKODYSTROPHY AND MYELIN""; ""Introduction""; ""Definition of leukodystrophies""; ""2 MYELINATION IN HEALTH AND DISEASE""; ""Introduction""; ""Oligodendrocytes have a highly polarized shape""; ""Molecular composition of myelin and oligodendrocyte membranes""; ""Molecular mechanisms of myelin membrane formation""; ""Reciprocal interactions between axons and oligodendrocytes""; ""Summary and conclusions""; ""3 THE ROLE OF ASTROCYTES IN WHITE MATTER DISEASE""; ""Introduction""; ""Cellular lineage systems in the mammalian brain""
""Astrocytes in development and adult life""""Leukodystrophies with distinct astrocyte pathology""; ""Possible mechanisms of white matter damage secondary to astrocyte dysfunction""; ""Summary and future perspectives""; ""4 MICROGLIA AND LEUKODYSTROPHIES""; ""Introduction""; ""Macrophage populations in the central nervous system""; ""Defining microglial activation""; ""Microglia in development and repair""; ""Brain colonization, self-renewal, and post-lesional recruitment of microglia""; ""Microglia in the pathogenesis of leukodystrophies""; ""Adrenoleukodystrophy""
""Does VLCFA accumulation cause microglial activation?""""How does microglial activation relate to demyelination in adrenoleukodystrophy?""; ""Metachromatic leukodystrophy""; ""Microglia in globoid cell leukodystrophy (Krabbe disease)""; ""The role of microglia in transplantation""; ""Concluding remarks""; ""5 X-LINKED ADRENOLEUKODYSTROPHY""; ""Introduction""; ""Biochemical and molecular basis""; ""Clinical features""; ""Diagnosis""; ""Animal models""; ""Pathogenesis""; ""Therapy in adrenoleukodystrophy""; ""Expanded screening for asymptomatic individuals""
""6 KRABBE DISEASE (GLOBOID CELL LEUKODYSTROPHY)""""Introduction""; ""Clinical features""; ""Diagnostic evaluation""; ""Pathological findings""; ""Biochemical findings""; ""Molecular genetics""; ""Newborn screening""; ""Studies in animal models""; ""Therapy""; ""Conclusions""; ""7 ALEXANDER DISEASE""; ""Introduction""; ""Clinical presentation""; ""MRI characteristics""; ""Pathology""; ""Diagnosis""; ""GFAP mutations""; ""Cases without GFAP mutations""; ""Recent cases""; ""Disease mechanisms""; ""Treatment""; ""Concluding remarks""; ""8 METACHROMATIC LEUKODYSTROPHY""
""Classification and definition""""Incidence and prevalence""; ""Genetics""; ""Biochemical background""; ""Pathophysiology""; ""Clinical features""; ""Laboratory and genetic diagnosis""; ""Therapy""; ""9 CANAVAN DISEASE""; ""Introduction""; ""Molecular basis""; ""Clinical features""; ""Variant forms of the disease""; ""Differential diagnosis""; ""Pathogenesis and pathophysiology""; ""Prognosis""; ""Epidemiology""; ""Gene therapy""; ""Prevention""; ""10 PELIZAEUS�MERZBACHER DISEASE: GENETIC MODELS AND MECHANISMS""; ""Involvement of myelin proteolipid protein""; ""The PLP1 gene""
""Genetics of PMD/SPG-2""
Record Nr. UNINA-9910810363003321
London, : Mac Keith Press, 2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The management of ADHD in children and young people / / edited by Val Harpin
The management of ADHD in children and young people / / edited by Val Harpin
Pubbl/distr/stampa London : , : Mac Keith Press, , 2017
Descrizione fisica 1 online resource (291 pages) : color illustrations
Soggetto topico Attention-deficit hyperactivity disorder
Soggetto genere / forma Electronic books.
ISBN 1-909962-75-9
1-909962-73-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910162763103321
London : , : Mac Keith Press, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The management of ADHD in children and young people / / edited by Val Harpin
The management of ADHD in children and young people / / edited by Val Harpin
Pubbl/distr/stampa London : , : Mac Keith Press, , 2017
Descrizione fisica 1 online resource (291 pages) : color illustrations
Soggetto topico Attention-deficit hyperactivity disorder
ISBN 1-909962-74-0
1-909962-75-9
1-909962-73-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910792620703321
London : , : Mac Keith Press, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The management of ADHD in children and young people / / edited by Val Harpin
The management of ADHD in children and young people / / edited by Val Harpin
Pubbl/distr/stampa London : , : Mac Keith Press, , 2017
Descrizione fisica 1 online resource (291 pages) : color illustrations
Soggetto topico Attention-deficit hyperactivity disorder
ISBN 1-909962-74-0
1-909962-75-9
1-909962-73-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910807486903321
London : , : Mac Keith Press, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The management of disorders of bladder and bowel control in childhood [[electronic resource] /] / Alexander von Gontard, Tryggve Nevéus
The management of disorders of bladder and bowel control in childhood [[electronic resource] /] / Alexander von Gontard, Tryggve Nevéus
Autore Gontard Alexander von
Pubbl/distr/stampa London, : Mac Keith Press, 2006
Descrizione fisica 1 online resource (368 p.)
Disciplina 618.92/62
Altri autori (Persone) NevéusTryggve
Collana Clinics in developmental medicine
Soggetto topico Urinary incontinence in children
Fecal incontinence in children
Soggetto genere / forma Electronic books.
ISBN 1-898683-77-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto CONTENTS; AUTHORS' APPOINTMENTS; PREFACE; ABBREVIATIONS; 1 INTRODUCTION; 2 CLASSIFICATION AND DEFINITIONS; Classification according to ICD-10 and DSM-IV; ICCS classification; 3 NORMAL BLADDER AND BOWEL DEVELOPMENT; Bladder and urinary tract; Bowel; 4 GENERAL PRINCIPLES: ASSESSMENT; History taking, charts and questionnaires; Physical examination; Laboratory investigations; Urodynamic studies; Ultrasound; Radiology and imaging; Cystoscopy and colonoscopy; Physiological examinations; Psychological and psychiatric assessment; Behavioural and psychiatric assessment; 5 GENERAL PRINCIPLES: TREATMENT
Non-pharmacological approachesPharmacological approaches; Surgical interventions; 6 NOCTURNAL ENURESIS; Definitions and classification; Epidemiology; Aetiology and pathophysiology; Psychological and psychiatric factors; Assessment; Treatment; Pharmacotherapy; Course and prognosis; Summary and clinical guidelines; 7 FUNCTIONAL URINARY INCONTINENCE; Definitions and classification; Epidemiology; Comorbid paediatric conditions; Behavioural disorders; Toilet training; General approaches to day-wetting children; Overactive bladder; Voiding postponement; Dysfunctional voiding; Stress incontinence
Giggle incontinenceUnderactive bladder; Other forms of functional urinary incontinence; 8 ORGANIC URINARY INCONTINENCE; Structural urinary incontinence; Neurogenic urinary incontinence; Urinary tract infection; Vulvovaginitis; Balanitis; Diabetes mellitus; Central diabetes insipidus; Nephrogenic diabetes insipidus; Epilepsy; Upper airway obstruction; Other causes of organic urinary incontinence; 9 FUNCTIONAL FAECAL INCONTINENCE (ENCOPRESIS); Classification and definitions; Epidemiology; Comorbid behavioural disorders; Specific psychological disorders in children with encopresis
Other psychological interpretations and modelsAetiology; General approaches in assessment; Standard assessment; Extended assessment; General approaches to treatment; Additional treatment components; Functional faecal incontinence (encopresis) with constipation; Functional faecal incontinence (encopresis) without constipation; Combined functional faecal incontinence (encopresis) and wetting; Toilet refusal syndrome; Toilet phobia; 10 ORGANIC FAECAL INCONTINENCE; Structural faecal incontinence; Neurogenic faecal incontinence; Other medical causes of faecal incontinence and constipation
Faecal incontinence in chronic paediatric illness11 CONCLUSION; APPENDIX 1 HISTORY OF WETTING PROBLEM AND POSSIBLE COMORBID DISORDERS; Presenting symptom; Nocturnal wetting; Daytime wetting and micturition problems during the day; Treatment trials; Encopresis; Child psychiatric history; Presenting symptom; Other problem areas; Personal and developmental history; Family history; APPENDIX 2 FREQUENCY-VOLUME CHART; Instructions for parents; 24- (48-) HOUR FREQUENCY-VOLUME CHART; APPENDIX 3 PARENTAL QUESTIONNAIRE:ENURESIS/URINARY INCONTINENCE; APPENDIX 4 ENCOPRESIS QUESTIONNAIRE - LONG VERSION
APPENDIX 5ENCOPRESIS QUESTIONNAIRE -SCREENING VERSION
Record Nr. UNINA-9910457444703321
Gontard Alexander von  
London, : Mac Keith Press, 2006
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The management of disorders of bladder and bowel control in childhood [[electronic resource] /] / Alexander von Gontard, Tryggve Nevéus
The management of disorders of bladder and bowel control in childhood [[electronic resource] /] / Alexander von Gontard, Tryggve Nevéus
Autore Gontard Alexander von
Pubbl/distr/stampa London, : Mac Keith Press, 2006
Descrizione fisica 1 online resource (368 p.)
Disciplina 618.92/62
Altri autori (Persone) NevéusTryggve
Collana Clinics in developmental medicine
Soggetto topico Urinary incontinence in children
Fecal incontinence in children
ISBN 1-898683-77-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto CONTENTS; AUTHORS' APPOINTMENTS; PREFACE; ABBREVIATIONS; 1 INTRODUCTION; 2 CLASSIFICATION AND DEFINITIONS; Classification according to ICD-10 and DSM-IV; ICCS classification; 3 NORMAL BLADDER AND BOWEL DEVELOPMENT; Bladder and urinary tract; Bowel; 4 GENERAL PRINCIPLES: ASSESSMENT; History taking, charts and questionnaires; Physical examination; Laboratory investigations; Urodynamic studies; Ultrasound; Radiology and imaging; Cystoscopy and colonoscopy; Physiological examinations; Psychological and psychiatric assessment; Behavioural and psychiatric assessment; 5 GENERAL PRINCIPLES: TREATMENT
Non-pharmacological approachesPharmacological approaches; Surgical interventions; 6 NOCTURNAL ENURESIS; Definitions and classification; Epidemiology; Aetiology and pathophysiology; Psychological and psychiatric factors; Assessment; Treatment; Pharmacotherapy; Course and prognosis; Summary and clinical guidelines; 7 FUNCTIONAL URINARY INCONTINENCE; Definitions and classification; Epidemiology; Comorbid paediatric conditions; Behavioural disorders; Toilet training; General approaches to day-wetting children; Overactive bladder; Voiding postponement; Dysfunctional voiding; Stress incontinence
Giggle incontinenceUnderactive bladder; Other forms of functional urinary incontinence; 8 ORGANIC URINARY INCONTINENCE; Structural urinary incontinence; Neurogenic urinary incontinence; Urinary tract infection; Vulvovaginitis; Balanitis; Diabetes mellitus; Central diabetes insipidus; Nephrogenic diabetes insipidus; Epilepsy; Upper airway obstruction; Other causes of organic urinary incontinence; 9 FUNCTIONAL FAECAL INCONTINENCE (ENCOPRESIS); Classification and definitions; Epidemiology; Comorbid behavioural disorders; Specific psychological disorders in children with encopresis
Other psychological interpretations and modelsAetiology; General approaches in assessment; Standard assessment; Extended assessment; General approaches to treatment; Additional treatment components; Functional faecal incontinence (encopresis) with constipation; Functional faecal incontinence (encopresis) without constipation; Combined functional faecal incontinence (encopresis) and wetting; Toilet refusal syndrome; Toilet phobia; 10 ORGANIC FAECAL INCONTINENCE; Structural faecal incontinence; Neurogenic faecal incontinence; Other medical causes of faecal incontinence and constipation
Faecal incontinence in chronic paediatric illness11 CONCLUSION; APPENDIX 1 HISTORY OF WETTING PROBLEM AND POSSIBLE COMORBID DISORDERS; Presenting symptom; Nocturnal wetting; Daytime wetting and micturition problems during the day; Treatment trials; Encopresis; Child psychiatric history; Presenting symptom; Other problem areas; Personal and developmental history; Family history; APPENDIX 2 FREQUENCY-VOLUME CHART; Instructions for parents; 24- (48-) HOUR FREQUENCY-VOLUME CHART; APPENDIX 3 PARENTAL QUESTIONNAIRE:ENURESIS/URINARY INCONTINENCE; APPENDIX 4 ENCOPRESIS QUESTIONNAIRE - LONG VERSION
APPENDIX 5ENCOPRESIS QUESTIONNAIRE -SCREENING VERSION
Record Nr. UNINA-9910779082603321
Gontard Alexander von  
London, : Mac Keith Press, 2006
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The management of disorders of bladder and bowel control in childhood [[electronic resource] /] / Alexander von Gontard, Tryggve Nevéus
The management of disorders of bladder and bowel control in childhood [[electronic resource] /] / Alexander von Gontard, Tryggve Nevéus
Autore Gontard Alexander von
Pubbl/distr/stampa London, : Mac Keith Press, 2006
Descrizione fisica 1 online resource (368 p.)
Disciplina 618.92/62
Altri autori (Persone) NevéusTryggve
Collana Clinics in developmental medicine
Soggetto topico Urinary incontinence in children
Fecal incontinence in children
ISBN 1-898683-77-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto CONTENTS; AUTHORS' APPOINTMENTS; PREFACE; ABBREVIATIONS; 1 INTRODUCTION; 2 CLASSIFICATION AND DEFINITIONS; Classification according to ICD-10 and DSM-IV; ICCS classification; 3 NORMAL BLADDER AND BOWEL DEVELOPMENT; Bladder and urinary tract; Bowel; 4 GENERAL PRINCIPLES: ASSESSMENT; History taking, charts and questionnaires; Physical examination; Laboratory investigations; Urodynamic studies; Ultrasound; Radiology and imaging; Cystoscopy and colonoscopy; Physiological examinations; Psychological and psychiatric assessment; Behavioural and psychiatric assessment; 5 GENERAL PRINCIPLES: TREATMENT
Non-pharmacological approachesPharmacological approaches; Surgical interventions; 6 NOCTURNAL ENURESIS; Definitions and classification; Epidemiology; Aetiology and pathophysiology; Psychological and psychiatric factors; Assessment; Treatment; Pharmacotherapy; Course and prognosis; Summary and clinical guidelines; 7 FUNCTIONAL URINARY INCONTINENCE; Definitions and classification; Epidemiology; Comorbid paediatric conditions; Behavioural disorders; Toilet training; General approaches to day-wetting children; Overactive bladder; Voiding postponement; Dysfunctional voiding; Stress incontinence
Giggle incontinenceUnderactive bladder; Other forms of functional urinary incontinence; 8 ORGANIC URINARY INCONTINENCE; Structural urinary incontinence; Neurogenic urinary incontinence; Urinary tract infection; Vulvovaginitis; Balanitis; Diabetes mellitus; Central diabetes insipidus; Nephrogenic diabetes insipidus; Epilepsy; Upper airway obstruction; Other causes of organic urinary incontinence; 9 FUNCTIONAL FAECAL INCONTINENCE (ENCOPRESIS); Classification and definitions; Epidemiology; Comorbid behavioural disorders; Specific psychological disorders in children with encopresis
Other psychological interpretations and modelsAetiology; General approaches in assessment; Standard assessment; Extended assessment; General approaches to treatment; Additional treatment components; Functional faecal incontinence (encopresis) with constipation; Functional faecal incontinence (encopresis) without constipation; Combined functional faecal incontinence (encopresis) and wetting; Toilet refusal syndrome; Toilet phobia; 10 ORGANIC FAECAL INCONTINENCE; Structural faecal incontinence; Neurogenic faecal incontinence; Other medical causes of faecal incontinence and constipation
Faecal incontinence in chronic paediatric illness11 CONCLUSION; APPENDIX 1 HISTORY OF WETTING PROBLEM AND POSSIBLE COMORBID DISORDERS; Presenting symptom; Nocturnal wetting; Daytime wetting and micturition problems during the day; Treatment trials; Encopresis; Child psychiatric history; Presenting symptom; Other problem areas; Personal and developmental history; Family history; APPENDIX 2 FREQUENCY-VOLUME CHART; Instructions for parents; 24- (48-) HOUR FREQUENCY-VOLUME CHART; APPENDIX 3 PARENTAL QUESTIONNAIRE:ENURESIS/URINARY INCONTINENCE; APPENDIX 4 ENCOPRESIS QUESTIONNAIRE - LONG VERSION
APPENDIX 5ENCOPRESIS QUESTIONNAIRE -SCREENING VERSION
Record Nr. UNINA-9910812790603321
Gontard Alexander von  
London, : Mac Keith Press, 2006
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The Musculoskeletal System in Children with Cerebral Palsy : 1st Edition
The Musculoskeletal System in Children with Cerebral Palsy : 1st Edition
Autore Gough Martin
Pubbl/distr/stampa London : , : Mac Keith Press, , 2022
Descrizione fisica 1 online resource (190 pages)
Altri autori (Persone) ShortlandAdam
Collana Clinics in Developmental Medicine
Soggetto topico Infants paralítics cerebrals - Rehabilitació
Paràlisi cerebral - Tractament
Soggetto genere / forma Llibres electrònics
ISBN 1-911612-55-7
1-911612-54-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910795773703321
Gough Martin  
London : , : Mac Keith Press, , 2022
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The Musculoskeletal System in Children with Cerebral Palsy : 1st Edition
The Musculoskeletal System in Children with Cerebral Palsy : 1st Edition
Autore Gough Martin
Pubbl/distr/stampa London : , : Mac Keith Press, , 2022
Descrizione fisica 1 online resource (190 pages)
Altri autori (Persone) ShortlandAdam
Collana Clinics in Developmental Medicine
Soggetto topico Infants paralítics cerebrals - Rehabilitació
Paràlisi cerebral - Tractament
Soggetto genere / forma Llibres electrònics
ISBN 1-911612-55-7
1-911612-54-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910806190903321
Gough Martin  
London : , : Mac Keith Press, , 2022
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui