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Translating epigenetics to the clinic / / Jeffrey Laurence
Translating epigenetics to the clinic / / Jeffrey Laurence
Autore Laurence Jeffrey
Pubbl/distr/stampa London, [England] : , : Academic Press, , 2017
Descrizione fisica 1 online resource (325 pages)
Disciplina 572.865
Soggetto topico Epigenetics
Epigenomics
Epigenesis, Genetic
Clinical Medicine
ISBN 0-12-800612-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Epigenetic regulation of open chromatin in pluripotent stem cells / H. Kobayashi, M. Lowe and N. Kikyo -- RNA epigenetics (epitranscriptomics) / N. Liu and T. Pan -- The nucleosome remodeling and deactylase complex in development and disease / J. Basta and M. Rauchman -- Epigenetics and muscle dysfunction in chronic obstructive pulmonary disease / E. Barreiro -- Clinical epigenetics of lung cancer / S.M. Langevin and K.T. Kelsey -- Epigenetics in cardiovascular disease / S. Aslibekyan, S.A. Claas and D.K. Arnett -- Epigenetics and arterial hypertension : evidences and perspectives / S. Friso, C.A. Carvjal, F. Pizzolo, C.E. Fardella and O. Olivieri -- Epigenetics in chronic pain / G. Bai, K. Ren and R. Dubner -- Epigenomics of alzheimer's disease / D.A. Bennett, L. Yu, J. Yang, H.-U. Klein and P.L. De Jager -- Prospective epigenetic paradigms and models for cellular senescence and epithelial-mesenchymal transition in organismal development and aging / S. Kishi, P.E. Bayliss and J. Hanai.
Record Nr. UNINA-9910583346803321
Laurence Jeffrey  
London, [England] : , : Academic Press, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Translating gene therapy to the clinic : techniques and approaches / / edited by Jeffrey Laurence, Michael Franklin
Translating gene therapy to the clinic : techniques and approaches / / edited by Jeffrey Laurence, Michael Franklin
Pubbl/distr/stampa London, England : , : Academic Press, , 2015
Descrizione fisica 1 online resource (347 p.)
Disciplina 616.042
Collana Advances in Translational Research
Soggetto topico Gene therapy
Human genetics
ISBN 0-12-800564-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Translating Gene Therapy to the Clinic: Techniques and Approaches; Copyright; Contents; Preface; REFERENCES; About the Editors; Contributors; Chapter 1 - Translating Genome Engineering to Survival; 1.1 ORIGINS; 1.2 SYNCHRONICITY OF DISCOVERIES; 1.3 GENE ADDITION; 1.4 FROM GENE ADDITION TO GENE EDITING; 1.5 THERAPY FOR GENETIC DISORDERS; 1.6 ROADMAP TO THE FUTURE; CONFLICT OF INTEREST; ACKNOWLEDGMENTS; REFERENCES; Chapter 2 - Pluripotent Stem Cells and Gene Therapy; 2.1 GENETIC APPROACHES TO PLURIPOTENCY; 2.2 TRANSCRIPTION FACTORS IMPORTANT FOR REPROGRAMMING TO PLURIPOTENCY
2.3 METHODS FOR GENETIC REPROGRAMMING2.4 CLINICAL TRANSLATION OF IPSCS; 2.5 CONCLUSION; REFERENCES; Chapter 3 - Genome Engineering for Therapeutic Applications; 3.1 INTRODUCTION; 3.2 CUSTOMIZABLE DNA-TARGETING PROTEINS; 3.3 GENOME EDITING WITH ENGINEERED NUCLEASES; 3.4 SYNTHETIC TRANSCRIPTION FACTORS FOR THERAPEUTIC APPLICATIONS; 3.5 CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 4 - Immune System Obstacles to In vivo Gene Transfer with Adeno-Associated Virus Vectors; 4.1 INTRODUCTION; 4.2 AAV VECTORS; 4.3 INNATE IMMUNITY IN AAV GENE TRANSFER; 4.4 T-CELL RESPONSES TO VECTORS
4.5 HUMORAL IMMUNITY4.6 CONCLUSIONS; ACKNOWLEDGMENT; REFERENCES; Chapter 5 - Risks of Insertional Mutagenesis by DNA Transposons in Cancer Gene Therapy; 5.1 INSERTIONAL MUTAGENESIS-THE DOWNSIDE OF GENE THERAPY?; 5.2 SLEEPING BEAUTY TRANSPOSON/TRANSPOSASE SYSTEM ADAPTED FOR GENE THERAPY; 5.3 PLASTICITY OF GENOMES AND GENE EXPRESSION IN HUMANS; 5.4 TRANSPOSON-MEDIATED GENE THERAPY IN THE CLINIC; 5.5 CONCLUSIONS; ACKNOWLEDGMENT; REFERENCES; Chapter 6 - Arthritis Gene Therapy: A Brief History and Perspective; 6.1 INTRODUCTION; 6.2 CONCEPTION AND STRATEGIES; 6.3 TECHNOLOGY DEVELOPMENT
6.4 UNRESOLVED ISSUES6.5 CLINICAL TRIALS; 6.6 VETERINARY APPLICATIONS; 6.7 OTHER APPLICATIONS OF INTRA-ARTICULAR GENE THERAPY; 6.8 COMMERCIALIZATION; 6.9 PERSPECTIVES; ACKNOWLEDGMENTS; REFERENCES; Chapter 7 - Type 1 Diabetes Mellitus: Immune Modulation as a Prerequisite for Successful Gene Therapy Strategies; 7.1 INTRODUCTION; 7.2 EFFECTIVE IMMUNE THERAPY/MODULATION: A PREREQUISITE FOR SUCCESSFUL GENE THERAPY OF TYPE 1 DIABETES; 7.3 TARGETED ISLET ANTIGEN RECOGNITION AND ANTIGEN-BASED THERAPIES; 7.4 BROAD IMMUNOSUPPRESSIVE THERAPIES; 7.5 IMMUNOTHERAPIES THAT TARGET EVENTS IN T CELL RESPONSE
7.6 PROSPECTS FOR IMMUNOTHERAPY IN PROTECTING NEO-BETA CELLS7.7 CONCLUSION; ACKNOWLEDGMENT; REFERENCES; Chapter 8 - Gene Therapy for Diabetes; LIST OF ABBREVIATIONS; 8.1 INTRODUCTION; 8.2 GENERATION OF Β CELLS FROM PANCREATIC MATURE NON-Β CELLS; 8.3 GENERATION OF Β CELLS FROM TISSUE PROGENITOR CELLS; 8.4 GENERATION OF Β CELLS FROM STEM CELLS; 8.5 GENERATION OF NEW Β CELLS BY INDUCING THEIR REPLICATION; 8.6 CLOSING REMARKS; ACKNOWLEDGMENTS; REFERENCES; Chapter 9 - Gene Therapy for Neurological Diseases; 9.1 INTRODUCTION; 9.2 VIRAL VECTORS FOR NEUROLOGICAL DISEASES
9.3 GENE THERAPY FOR CHRONIC PAIN
Record Nr. UNINA-9910787927203321
London, England : , : Academic Press, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Translating gene therapy to the clinic : techniques and approaches / / edited by Jeffrey Laurence, Michael Franklin
Translating gene therapy to the clinic : techniques and approaches / / edited by Jeffrey Laurence, Michael Franklin
Pubbl/distr/stampa London, England : , : Academic Press, , 2015
Descrizione fisica 1 online resource (347 p.)
Disciplina 616.042
Collana Advances in Translational Research
Soggetto topico Gene therapy
Human genetics
ISBN 0-12-800564-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Translating Gene Therapy to the Clinic: Techniques and Approaches; Copyright; Contents; Preface; REFERENCES; About the Editors; Contributors; Chapter 1 - Translating Genome Engineering to Survival; 1.1 ORIGINS; 1.2 SYNCHRONICITY OF DISCOVERIES; 1.3 GENE ADDITION; 1.4 FROM GENE ADDITION TO GENE EDITING; 1.5 THERAPY FOR GENETIC DISORDERS; 1.6 ROADMAP TO THE FUTURE; CONFLICT OF INTEREST; ACKNOWLEDGMENTS; REFERENCES; Chapter 2 - Pluripotent Stem Cells and Gene Therapy; 2.1 GENETIC APPROACHES TO PLURIPOTENCY; 2.2 TRANSCRIPTION FACTORS IMPORTANT FOR REPROGRAMMING TO PLURIPOTENCY
2.3 METHODS FOR GENETIC REPROGRAMMING2.4 CLINICAL TRANSLATION OF IPSCS; 2.5 CONCLUSION; REFERENCES; Chapter 3 - Genome Engineering for Therapeutic Applications; 3.1 INTRODUCTION; 3.2 CUSTOMIZABLE DNA-TARGETING PROTEINS; 3.3 GENOME EDITING WITH ENGINEERED NUCLEASES; 3.4 SYNTHETIC TRANSCRIPTION FACTORS FOR THERAPEUTIC APPLICATIONS; 3.5 CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Chapter 4 - Immune System Obstacles to In vivo Gene Transfer with Adeno-Associated Virus Vectors; 4.1 INTRODUCTION; 4.2 AAV VECTORS; 4.3 INNATE IMMUNITY IN AAV GENE TRANSFER; 4.4 T-CELL RESPONSES TO VECTORS
4.5 HUMORAL IMMUNITY4.6 CONCLUSIONS; ACKNOWLEDGMENT; REFERENCES; Chapter 5 - Risks of Insertional Mutagenesis by DNA Transposons in Cancer Gene Therapy; 5.1 INSERTIONAL MUTAGENESIS-THE DOWNSIDE OF GENE THERAPY?; 5.2 SLEEPING BEAUTY TRANSPOSON/TRANSPOSASE SYSTEM ADAPTED FOR GENE THERAPY; 5.3 PLASTICITY OF GENOMES AND GENE EXPRESSION IN HUMANS; 5.4 TRANSPOSON-MEDIATED GENE THERAPY IN THE CLINIC; 5.5 CONCLUSIONS; ACKNOWLEDGMENT; REFERENCES; Chapter 6 - Arthritis Gene Therapy: A Brief History and Perspective; 6.1 INTRODUCTION; 6.2 CONCEPTION AND STRATEGIES; 6.3 TECHNOLOGY DEVELOPMENT
6.4 UNRESOLVED ISSUES6.5 CLINICAL TRIALS; 6.6 VETERINARY APPLICATIONS; 6.7 OTHER APPLICATIONS OF INTRA-ARTICULAR GENE THERAPY; 6.8 COMMERCIALIZATION; 6.9 PERSPECTIVES; ACKNOWLEDGMENTS; REFERENCES; Chapter 7 - Type 1 Diabetes Mellitus: Immune Modulation as a Prerequisite for Successful Gene Therapy Strategies; 7.1 INTRODUCTION; 7.2 EFFECTIVE IMMUNE THERAPY/MODULATION: A PREREQUISITE FOR SUCCESSFUL GENE THERAPY OF TYPE 1 DIABETES; 7.3 TARGETED ISLET ANTIGEN RECOGNITION AND ANTIGEN-BASED THERAPIES; 7.4 BROAD IMMUNOSUPPRESSIVE THERAPIES; 7.5 IMMUNOTHERAPIES THAT TARGET EVENTS IN T CELL RESPONSE
7.6 PROSPECTS FOR IMMUNOTHERAPY IN PROTECTING NEO-BETA CELLS7.7 CONCLUSION; ACKNOWLEDGMENT; REFERENCES; Chapter 8 - Gene Therapy for Diabetes; LIST OF ABBREVIATIONS; 8.1 INTRODUCTION; 8.2 GENERATION OF Β CELLS FROM PANCREATIC MATURE NON-Β CELLS; 8.3 GENERATION OF Β CELLS FROM TISSUE PROGENITOR CELLS; 8.4 GENERATION OF Β CELLS FROM STEM CELLS; 8.5 GENERATION OF NEW Β CELLS BY INDUCING THEIR REPLICATION; 8.6 CLOSING REMARKS; ACKNOWLEDGMENTS; REFERENCES; Chapter 9 - Gene Therapy for Neurological Diseases; 9.1 INTRODUCTION; 9.2 VIRAL VECTORS FOR NEUROLOGICAL DISEASES
9.3 GENE THERAPY FOR CHRONIC PAIN
Record Nr. UNINA-9910813550803321
London, England : , : Academic Press, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Translating regenerative medicine to the clinic / / edited by Jeffrey Laurence, Division of Hematology-Medical Oncology Weill Cornell Medical College and New York Presbyterian Hospital New York, NY, USA [and three others] ; contributors, Graca Almeida-Porada [and eighty-four others]
Translating regenerative medicine to the clinic / / edited by Jeffrey Laurence, Division of Hematology-Medical Oncology Weill Cornell Medical College and New York Presbyterian Hospital New York, NY, USA [and three others] ; contributors, Graca Almeida-Porada [and eighty-four others]
Pubbl/distr/stampa Amsterdam, [Netherlands] : , : Academic Press, , 2016
Descrizione fisica 1 online resource (356 p.)
Disciplina 571.889
Collana Advances in Translational Medicine
Soggetto topico Regenerative medicine
Clinical medicine
ISBN 0-12-800552-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Translating Regenerative Medicine to the Clinic; Copyright; Contents; Contributors; I - Introduction; 1 - Regenerative Medicine: The Hurdles and Hopes; Key Concepts; 1. INTRODUCTION; 2. ON THE ORIGINS OF REGENERATIVE MEDICINE; 3. FROM CELLS AND SCAFFOLDS TO TISSUES AND ORGANS; 4. BIOMATERIALS, TISSUE AND ORGAN BIOENGINEERING; 5. GENE THERAPY; 6. STEM CELL THERAPIES; 7. FUTURE DIRECTIONS; REFERENCES; II - Biomaterials and Tissue/Organ Bioengineering; 2 - Extracellular Matrix as an Inductive Scaffold for Functional Tissue Reconstruction; Key Concepts; 1. INTRODUCTION
5.4 Undesirable Responses to ECM Scaffold Materials6. CONCLUSIONS; ACKNOWLEDGMENTS; REFERENCES; 3 - Whole-Organ Bioengineering-Current Tales of Modern Alchemy; Key Concepts; 1. INTRODUCTION; 2. CURRENT STATUS OF ORGAN TRANSPLANTATION; 3. CURRENT STATUS ON ORGAN BIOENGINEERING; 3.1 Liver; 3.2 Intestine; 3.3 Kidney; 3.4 Heart; 3.5 Pancreas; 3.6 Lungs; 4. CURRENT APPLICATIONS FOR BIOENGINEERED ORGANS; 5. CURRENT LIMITATIONS; 5.1 Cell Sources and Expansion; 5.2 Assembly of Patent Vascular Networks; 5.3 Enabling Bioreactor Technologies; 5.4 Regulatory Challenges, Scaling Up, and Other Issues
6. CONCLUSIONSREFERENCES; 4 - Regenerative Implants for Cardiovascular Tissue Engineering; 1. INTRODUCTION; 1.1 The Path to a Regenerative Approach; 1.2 Brief Historical Overview of Vascular, Heart Valve, and Heart Implants; 1.2.1 Vascular Implants; 1.2.2 Heart Valve; 1.2.3 Whole Heart; 2. TYPES OF REGENERATIVE IMPLANTS-THE CONTINUITY BRIDGE; 2.1 Synthetic; 2.1.1 Degradable Synthetic Polymers; 2.1.2 Fabrication Methods; 2.2 Biologic; 2.2.1 ECM Gels; 2.2.2 Decellularized Scaffolds; 2.2.3 Hybrid; 3. FUNCTION OF IMPLANTS; 3.1 Implants as a Cell Delivery Vehicle Grown In Vitro
3.1.1 Endothelial Progenitor Cells and MSCs3.1.2 Embryonic and Inducible Stem Cells; 3.1.3 BM Cells; 3.1.4 Cell Seeding Techniques; 3.2 Implants as an In Situ "Cell-Free" Tissue Forming Device; 3.3 Implants as a Drug Delivery Vehicle; 4. CLINICAL APPLICATIONS IN CARDIOVASCULAR REPAIR; 4.1 Vascular; 4.1.1 Vascular Patch; 4.1.2 Vascular Grafts; 4.2 Heart Valve; 4.3 Heart; 5. CONCLUSION; ACKNOWLEDGMENT; REFERENCES; 5 - Tissue Engineering and Regenerative Medicine: Gastrointestinal Application; Key Concepts; 1. THE GASTROINTESTINAL TRACT: OVERVIEW; 2. NEURODEGENERATIVE DISEASES OF THE GI TRACT
3. CELL SOURCE IN REGENERATING THE NEUROMUSCULATURE OF THE GI TRACT
Record Nr. UNINA-9910797843003321
Amsterdam, [Netherlands] : , : Academic Press, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Translating regenerative medicine to the clinic / / edited by Jeffrey Laurence, Division of Hematology-Medical Oncology Weill Cornell Medical College and New York Presbyterian Hospital New York, NY, USA [and three others] ; contributors, Graca Almeida-Porada [and eighty-four others]
Translating regenerative medicine to the clinic / / edited by Jeffrey Laurence, Division of Hematology-Medical Oncology Weill Cornell Medical College and New York Presbyterian Hospital New York, NY, USA [and three others] ; contributors, Graca Almeida-Porada [and eighty-four others]
Pubbl/distr/stampa Amsterdam, [Netherlands] : , : Academic Press, , 2016
Descrizione fisica 1 online resource (356 p.)
Disciplina 571.889
Collana Advances in Translational Medicine
Soggetto topico Regenerative medicine
Clinical medicine
ISBN 0-12-800552-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Translating Regenerative Medicine to the Clinic; Copyright; Contents; Contributors; I - Introduction; 1 - Regenerative Medicine: The Hurdles and Hopes; Key Concepts; 1. INTRODUCTION; 2. ON THE ORIGINS OF REGENERATIVE MEDICINE; 3. FROM CELLS AND SCAFFOLDS TO TISSUES AND ORGANS; 4. BIOMATERIALS, TISSUE AND ORGAN BIOENGINEERING; 5. GENE THERAPY; 6. STEM CELL THERAPIES; 7. FUTURE DIRECTIONS; REFERENCES; II - Biomaterials and Tissue/Organ Bioengineering; 2 - Extracellular Matrix as an Inductive Scaffold for Functional Tissue Reconstruction; Key Concepts; 1. INTRODUCTION
5.4 Undesirable Responses to ECM Scaffold Materials6. CONCLUSIONS; ACKNOWLEDGMENTS; REFERENCES; 3 - Whole-Organ Bioengineering-Current Tales of Modern Alchemy; Key Concepts; 1. INTRODUCTION; 2. CURRENT STATUS OF ORGAN TRANSPLANTATION; 3. CURRENT STATUS ON ORGAN BIOENGINEERING; 3.1 Liver; 3.2 Intestine; 3.3 Kidney; 3.4 Heart; 3.5 Pancreas; 3.6 Lungs; 4. CURRENT APPLICATIONS FOR BIOENGINEERED ORGANS; 5. CURRENT LIMITATIONS; 5.1 Cell Sources and Expansion; 5.2 Assembly of Patent Vascular Networks; 5.3 Enabling Bioreactor Technologies; 5.4 Regulatory Challenges, Scaling Up, and Other Issues
6. CONCLUSIONSREFERENCES; 4 - Regenerative Implants for Cardiovascular Tissue Engineering; 1. INTRODUCTION; 1.1 The Path to a Regenerative Approach; 1.2 Brief Historical Overview of Vascular, Heart Valve, and Heart Implants; 1.2.1 Vascular Implants; 1.2.2 Heart Valve; 1.2.3 Whole Heart; 2. TYPES OF REGENERATIVE IMPLANTS-THE CONTINUITY BRIDGE; 2.1 Synthetic; 2.1.1 Degradable Synthetic Polymers; 2.1.2 Fabrication Methods; 2.2 Biologic; 2.2.1 ECM Gels; 2.2.2 Decellularized Scaffolds; 2.2.3 Hybrid; 3. FUNCTION OF IMPLANTS; 3.1 Implants as a Cell Delivery Vehicle Grown In Vitro
3.1.1 Endothelial Progenitor Cells and MSCs3.1.2 Embryonic and Inducible Stem Cells; 3.1.3 BM Cells; 3.1.4 Cell Seeding Techniques; 3.2 Implants as an In Situ "Cell-Free" Tissue Forming Device; 3.3 Implants as a Drug Delivery Vehicle; 4. CLINICAL APPLICATIONS IN CARDIOVASCULAR REPAIR; 4.1 Vascular; 4.1.1 Vascular Patch; 4.1.2 Vascular Grafts; 4.2 Heart Valve; 4.3 Heart; 5. CONCLUSION; ACKNOWLEDGMENT; REFERENCES; 5 - Tissue Engineering and Regenerative Medicine: Gastrointestinal Application; Key Concepts; 1. THE GASTROINTESTINAL TRACT: OVERVIEW; 2. NEURODEGENERATIVE DISEASES OF THE GI TRACT
3. CELL SOURCE IN REGENERATING THE NEUROMUSCULATURE OF THE GI TRACT
Record Nr. UNINA-9910814346303321
Amsterdam, [Netherlands] : , : Academic Press, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Translation initiation : extract systems and molecular genetics / edited by Jon Lorsch
Translation initiation : extract systems and molecular genetics / edited by Jon Lorsch
Pubbl/distr/stampa Amsterdam ; Boston : Academic Press, c2007
Descrizione fisica xlii, 377 p., [4] p. di tav. : ill. ; 24 cm
Altri autori (Persone) Lorsch, Jon
Collana Methods in enzymology ; 429
Soggetto topico Espressione genica - Regolazione
ISBN 9780123741912
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNISALENTO-991003432599707536
Amsterdam ; Boston : Academic Press, c2007
Materiale a stampa
Lo trovi qui: Univ. del Salento
Opac: Controlla la disponibilità qui
Translation initiation : reconstituted systems and biophysical methods / edited by Jon Lorsch
Translation initiation : reconstituted systems and biophysical methods / edited by Jon Lorsch
Pubbl/distr/stampa San Diego, Calif : Academic Press, c2007
Descrizione fisica xlvi, 463 p., [16] p. di tav. : ill. ; 24 cm.
Altri autori (Persone) Lorsch, Jon
Collana Methods in enzymology ; 430
Soggetto topico Espressione genica - Regolazione
ISBN 9780123739698
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNISALENTO-991003432879707536
San Diego, Calif : Academic Press, c2007
Materiale a stampa
Lo trovi qui: Univ. del Salento
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Translational advances in gynecologic cancers / / edited by Michael J. Birrer, Lorenzo Ceppi
Translational advances in gynecologic cancers / / edited by Michael J. Birrer, Lorenzo Ceppi
Pubbl/distr/stampa London, [England] : , : Academic Press, , 2017
Descrizione fisica 1 online resource (356 pages) : illustrations
Disciplina 616.99465
Soggetto topico Generative organs, Female - Cancer
ISBN 0-12-803798-9
0-12-803741-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Origins of epithelial ovarian cancer / L. Dubeau and J. Texeira -- Ovarian cancer genomics / L. Ceppi and M.J. Birrer -- Epigenetics / J.T. Pepin, H. Cardenas, K.P. Nephew and D. Matei -- Timing of ctyoreductive surgery in the treatment of advanced epithelial ovarian carcinoma / C.M. St. Clair, F. Khoury-Collado and D.S. Chi -- Angiogenesis / A.A. Secord and S. Siamakpour-Reihani -- Homologous recombination and BRCA genes in ovarian cancer / J.F. Liu and P.A. Konstantinopoulos -- Molecular basis of PARP inhibition and future opportunities in ovarian cancer therapy / B.L. Collins, A.N. Gonzalez, A. Hanbury, L. Ceppi and R.T. Penson -- Ovarian cancer / L.P. Martin and R. J. Schilder -- Novel chemotherapy tools / D.S. Dizon -- Updates on rare epithelial ovarian carcinoma / J. Bergstrom, I.-M. Shih and A.N. Fader -- Endometrial cancer genomics / M.E. Urick and D.W. Bell -- Sentinel lymph node mapping procedures in endometrial cancer / D.M. Boruta II -- The role of radiation in uterine cancer / A.L. Russo -- Novel therapies for advanced cervical cancer / K.S. Tewari -- New therapies in vulvar cancer / M.H.M. Oonk and A.G.J. van der Zee -- Fertility and cancer / M.E. Sabatini.
Record Nr. UNINA-9910583364103321
London, [England] : , : Academic Press, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Translational bioinformatics and systems biology methods for personalized medicine / / Qing Yan
Translational bioinformatics and systems biology methods for personalized medicine / / Qing Yan
Autore Yan Qing
Pubbl/distr/stampa Cambridge, England : , : Academic Press, , 2017
Descrizione fisica 1 online resource (184 pages) : illustrations
Disciplina 572.80285
Soggetto topico Bioinformatics
Bioinformatics - Statistical methods
ISBN 0-12-804388-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910583363103321
Yan Qing  
Cambridge, England : , : Academic Press, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Translational cardiometabolic genomic medicine / / edited by Annabelle Roguez-Oquendo
Translational cardiometabolic genomic medicine / / edited by Annabelle Roguez-Oquendo
Pubbl/distr/stampa Amsterdam, Netherlands : , : Academic Press, , 2016
Descrizione fisica 1 online resource (0 p.)
Disciplina 616.042
Soggetto topico Medical genetics
Genomics
ISBN 0-12-799961-2
0-12-800474-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chapter 1. Metabolomics and Cardiovascular Medicine -- Chapter 2. Modern Transcriptomics and Small RNA Diversity -- Chapter 3. A Systems-Level Understanding of Cardiovascular Disease through Networks -- Chapter 4. Using Information about DNA Structure and Dynamics from Experiment and Simulation to Give Insight into Genome-Wide Association Studies -- Chapter 5. Genomic Medicine and Lipid Metabolism: LDL Targets and Stem Cell Research Approaches -- Chapter 6. Discovery of High-Density Lipoprotein Gene Targets from Classical Genetics to Genome-Wide Association Studies -- Chapter 7. The Genetics of Obesity -- Chapter 8. The Epidemiology and Genetics of Vascular Dementia: Current Knowledge and Next Steps -- Chapter 9. Genomic Medicine and Ethnic Differences in Cardiovascular Disease Risk -- Chapter 10. Genomics-Guided Immunotherapy of Human Epithelial Ovarian Cancer -- Chapter 11. Overview of the Intersection of Genomics of Cholesterol Metabolism and Cardiometabolic Disease with Reproductive Health, Especially in Women -- Chapter 12. Overview of Intersection of Genomics of Cardiometabolic Disease and Other Disease States, Such as Eye Health (Macular Degeneration) -- Chapter 13. Translating Genomic Research to the Marketplace.
Record Nr. UNINA-9910797539603321
Amsterdam, Netherlands : , : Academic Press, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
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