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Copper-oxygen chemistry / / edited by Kenneth D. Karlin, Shinobu Itoh
| Copper-oxygen chemistry / / edited by Kenneth D. Karlin, Shinobu Itoh |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, 2011 |
| Descrizione fisica | 1 online resource (484 p.) |
| Disciplina | 612.3/924 |
| Altri autori (Persone) |
KarlinKenneth D. <1948->
ItohShinobu |
| Collana | Wiley series of reactive intermediates in chemistry and biology |
| Soggetto topico |
Copper proteins
Copper - Peroxidation Bioinorganic chemistry |
| ISBN |
1-283-25785-8
9786613257857 1-118-09435-2 1-118-09436-0 1-118-09434-4 |
| Classificazione | SCI007000 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
COPPER-OXYGEN CHEMISTRY; CONTENTS; Preface to Series; Introduction; Contributors; 1 Insights into the Proposed Copper-Oxygen Intermediates that Regulate the Mechanism of Reactions Catalyzed by Dopamine ß-Monooxygenase, Peptidylglycine a-Hydroxylating Monooxygenase, and Tyramine ß-Monooxygenase; 2 Copper Dioxygenases; 3 Amine Oxidase and Galactose Oxidase; 4 Energy Conversion and Conservation by Cytochrome Oxidases; 5 Multicopper Proteins; 6 Structure and Reactivity of Copper-Oxygen Species Revealed by Competitive Oxygen-18 Isotope Effects
7 Theoretical Aspects of Dioxygen Activation in Dicopper Enzymes8 Chemical Reactivity of Copper Active-Oxygen Complexes; 9 Cytochrome c Oxidase and Models; 10 Supramolecular Copper Dioxygen Chemistry; 11 Organic Synthetic Methods Using Copper Oxygen Chemistry; Index; Colour Plates |
| Record Nr. | UNINA-9910139594703321 |
| Hoboken, N.J., : Wiley, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Flexible viruses [[electronic resource] ] : structural disorder in viral proteins / / edited by Vladimir Uversky, Sonia Longhi
| Flexible viruses [[electronic resource] ] : structural disorder in viral proteins / / edited by Vladimir Uversky, Sonia Longhi |
| Autore | Uversky Vladimir N |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2012 |
| Descrizione fisica | 1 online resource (534 p.) |
| Disciplina | 612/.015756 |
| Altri autori (Persone) | LonghiSonia |
| Collana | Wiley series in protein and peptide science |
| Soggetto topico | Viral proteins |
| ISBN |
1-283-31596-3
9786613315960 1-118-13556-3 1-118-13557-1 1-118-13554-7 |
| Classificazione | SCI007000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
FLEXIBLE VIRUSES; CONTENTS; Preface; Introduction to the Wiley Series on Protein and Peptide Science; Contributors; 1 Do Viral Proteins Possess Unique Features?; 2 Functional Role of Structural Disorder in Capsid Proteins; 3 Structural Disorder Within the Nucleoprotein and Phosphoprotein from Measles, Nipah, and Hendra Viruses; 4 Structural Disorder Within Sendai Virus Nucleoprotein and Phosphoprotein; 5 Structural Disorder in Proteins of the Rhabdoviridae Replication Complex; 6 Structural Disorder in Matrix Proteins of HIV-Related Viruses
7 Structural Disorder in Proteins From Influenza Virus8 Making Order in the Intrinsically Disordered Regions of HIV-1 Vif Protein; 9 Order from Disorder: Structure, Function, and Dynamics of the HIV-1 Transactivator of Transcription; 10 Intrinsically Disordered Domains of Sesbania Mosaic Virus Encoded Proteins; 11 Intrinsic Disorder in Genome-Linked Viral Proteins VPgs of Potyviruses; 12 Intrinsic Disorder in the Human Papillomavirus E7 Protein; 13 The Semliki Forest Virus Capsid Protease is Disordered and Yet Displays Catalytic Activity 14 Core-lations Between Intrinsic Disorder and Multifaceted Activities in Hepatitis C Virus and Related Viruses15 The NS5A Domain II of HCV: Conservation of Intrinsic Disorder in Several Genotypes; 16 Bacteriophage l N Protein Disorder-Order Transitions Upon Interactions with RNA or Proteins; 17 N-Terminal Extension Region of Hordeivirus Movement TGB1 Protein Consists of Two Domains with Different Content of Disordered Structure; Index |
| Record Nr. | UNINA-9910141216203321 |
Uversky Vladimir N
|
||
| Hoboken, N.J., : Wiley, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Flexible viruses : structural disorder in viral proteins / / edited by Vladimir Uversky, Sonia Longhi
| Flexible viruses : structural disorder in viral proteins / / edited by Vladimir Uversky, Sonia Longhi |
| Autore | Uversky Vladimir N |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2012 |
| Descrizione fisica | 1 online resource (534 p.) |
| Disciplina | 612/.015756 |
| Altri autori (Persone) | LonghiSonia |
| Collana | Wiley series in protein and peptide science |
| Soggetto topico | Viral proteins |
| ISBN |
1-283-31596-3
9786613315960 1-118-13556-3 1-118-13557-1 1-118-13554-7 |
| Classificazione | SCI007000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
FLEXIBLE VIRUSES; CONTENTS; Preface; Introduction to the Wiley Series on Protein and Peptide Science; Contributors; 1 Do Viral Proteins Possess Unique Features?; 2 Functional Role of Structural Disorder in Capsid Proteins; 3 Structural Disorder Within the Nucleoprotein and Phosphoprotein from Measles, Nipah, and Hendra Viruses; 4 Structural Disorder Within Sendai Virus Nucleoprotein and Phosphoprotein; 5 Structural Disorder in Proteins of the Rhabdoviridae Replication Complex; 6 Structural Disorder in Matrix Proteins of HIV-Related Viruses
7 Structural Disorder in Proteins From Influenza Virus8 Making Order in the Intrinsically Disordered Regions of HIV-1 Vif Protein; 9 Order from Disorder: Structure, Function, and Dynamics of the HIV-1 Transactivator of Transcription; 10 Intrinsically Disordered Domains of Sesbania Mosaic Virus Encoded Proteins; 11 Intrinsic Disorder in Genome-Linked Viral Proteins VPgs of Potyviruses; 12 Intrinsic Disorder in the Human Papillomavirus E7 Protein; 13 The Semliki Forest Virus Capsid Protease is Disordered and Yet Displays Catalytic Activity 14 Core-lations Between Intrinsic Disorder and Multifaceted Activities in Hepatitis C Virus and Related Viruses15 The NS5A Domain II of HCV: Conservation of Intrinsic Disorder in Several Genotypes; 16 Bacteriophage l N Protein Disorder-Order Transitions Upon Interactions with RNA or Proteins; 17 N-Terminal Extension Region of Hordeivirus Movement TGB1 Protein Consists of Two Domains with Different Content of Disordered Structure; Index |
| Record Nr. | UNINA-9910809692803321 |
|
Uversky Vladimir N
|
||
| Hoboken, N.J., : Wiley, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Microcalorimetry of macromolecules [[electronic resource] ] : the physical basis of biological structures / / Peter L. Privalov
| Microcalorimetry of macromolecules [[electronic resource] ] : the physical basis of biological structures / / Peter L. Privalov |
| Autore | Privalov Peter L |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, 2012 |
| Descrizione fisica | 1 online resource (422 p.) |
| Disciplina | 547/.7 |
| Collana | Wiley series in protein and peptide science Microcalorimetry of macromolecules |
| Soggetto topico |
Macromolecules
Macromolecules - Analysis Calorimeters |
| ISBN |
1-280-68551-4
9786613662453 1-118-33749-2 1-118-33750-6 1-118-33747-6 |
| Classificazione | SCI007000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MICROCALORIMETRY OF MACROMOLECULES; CONTENTS; 1: INTRODUCTION; 2: METHODOLOGY; 2.1. THERMODYNAMIC BASICS OF CALORIMETRY; 2.1.1. Energy; 2.1.2. Enthalpy; 2.1.3. Temperature; 2.1.4. Energy Units; 2.1.5. Heat Capacity; 2.1.6. Kirchhoff's Relation; 2.1.7. Entropy; 2.1.8. Gibbs Free Energy; 2.2. EQUILIBRIUM ANALYSIS; 2.2.1. Two-State Transition; 2.2.2. Derivatives of the Equilibrium Constant; 2.3. AQUEOUS SOLUTIONS; 2.3.1. Specificity of Water as a Solvent; 2.3.2. Acid-Base Equilibrium; 2.3.3. Partial Quantities; 2.4. TRANSFER OF SOLUTES INTO THE AQUEOUS PHASE; 2.4.1. Hydration Effects
2.4.2. Hydrophobic Force2.4.3. Hydration of Polar and Nonpolar Groups; REFERENCES; 3: CALORIMETRY; 3.1. ISOTHERMAL REACTION MICROCALORIMETRY; 3.1.1. The Heat of Mixing Reaction; 3.1.2. Mixing of Reagents in Comparable Volumes; 3.1.3. Isothermal Titration Microcalorimeter; 3.1.4. ITC Experiments; 3.1.5. Analysis of the ITC Data; 3.2. HEAT CAPACITY CALORIMETRY; 3.2.1. Technical Problems; 3.2.2. Differential Scanning Microcalorimeter; 3.2.3. Determination of the Partial Heat Capacity of Solute Molecules; 3.2.4. DSC Experiments 3.2.5. Determination of the Enthalpy of a Temperature-Induced Process3.2.6. Determination of the van't Hoff Enthalpy; 3.2.7. Multimolecular Two-State Transition; 3.2.8. Analysis of the Complex Heat Capacity Profile; 3.2.9. Correction for Components Refolding; 3.3. PRESSURE PERTURBATION CALORIMETRY; 3.3.1. Heat Effect of Changing Pressure; 3.3.2. Pressure Perturbation Experiment; REFERENCES; 4: MACROMOLECULES; 4.1. EVOLUTION OF THE CONCEPT; 4.2. PROTEINS; 4.2.1. Chemical Structure; 4.2.2. Physical Structure; 4.2.3. Restrictions on the Conformation of Polypeptide Chains 4.2.4. Regular Conformations of Polypeptide Chain Proteins4.3. HIERARCHY IN PROTEIN STRUCTURE; 4.3.1. Tertiary Structure of Proteins; 4.3.2. Quaternary Structure of Proteins; 4.4. NUCLEIC ACIDS; 4.4.1. Chemical Structure; 4.4.2. Physical Structure; REFERENCES; 5: THE α-HELIX AND α-HELICAL COILED-COIL; 5.1. THE α-HELIX; 5.1.1. Calorimetric Studies of α-Helix Unfolding-Refolding; 5.1.2. Analysis of the Heat Capacity Function; 5.2. α-HELICAL COILED-COILS; 5.2.1. Two-Stranded Coiled-Coils; 5.2.2. Three-Stranded Coiled-Coils; 5.3. α-HELICAL COILED-COIL PROTEINS; 5.3.1. Muscle Proteins 5.3.2. Myosin Rod5.3.3. Paramyosin; 5.3.4. Tropomyosin; 5.3.5. Leucine Zipper; 5.3.6. Discreteness of the Coiled-Coils; REFERENCES; 6: POLYPROLINE-II COILED-COILS; 6.1. COLLAGENS; 6.1.1. Collagen Superhelix; 6.1.2. Hydrogen Bonds in Collagen; 6.1.3. Stability of Collagens; 6.1.4. Role of Pyrrolidine Rings in Collagen Stabilization; 6.2. CALORIMETRIC STUDIES OF COLLAGENS; 6.2.1. Enthalpy and Entropy of Collagen Melting; 6.2.2. Correlation between Thermodynamic and Structural Characteristics of Collagens; 6.2.3. Role of Water in Maintaining the Collagen Structure 6.3. THERMODYNAMICS OF COLLAGENS |
| Record Nr. | UNINA-9910139087003321 |
|
Privalov Peter L
|
||
| Hoboken, N.J., : Wiley, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Microcalorimetry of macromolecules : the physical basis of biological structures / / Peter L. Privalov
| Microcalorimetry of macromolecules : the physical basis of biological structures / / Peter L. Privalov |
| Autore | Privalov Peter L |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, 2012 |
| Descrizione fisica | 1 online resource (422 p.) |
| Disciplina | 547/.7 |
| Collana | Wiley series in protein and peptide science Microcalorimetry of macromolecules |
| Soggetto topico |
Macromolecules
Macromolecules - Analysis Calorimeters |
| ISBN |
1-280-68551-4
9786613662453 1-118-33749-2 1-118-33750-6 1-118-33747-6 |
| Classificazione | SCI007000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MICROCALORIMETRY OF MACROMOLECULES; CONTENTS; 1: INTRODUCTION; 2: METHODOLOGY; 2.1. THERMODYNAMIC BASICS OF CALORIMETRY; 2.1.1. Energy; 2.1.2. Enthalpy; 2.1.3. Temperature; 2.1.4. Energy Units; 2.1.5. Heat Capacity; 2.1.6. Kirchhoff's Relation; 2.1.7. Entropy; 2.1.8. Gibbs Free Energy; 2.2. EQUILIBRIUM ANALYSIS; 2.2.1. Two-State Transition; 2.2.2. Derivatives of the Equilibrium Constant; 2.3. AQUEOUS SOLUTIONS; 2.3.1. Specificity of Water as a Solvent; 2.3.2. Acid-Base Equilibrium; 2.3.3. Partial Quantities; 2.4. TRANSFER OF SOLUTES INTO THE AQUEOUS PHASE; 2.4.1. Hydration Effects
2.4.2. Hydrophobic Force2.4.3. Hydration of Polar and Nonpolar Groups; REFERENCES; 3: CALORIMETRY; 3.1. ISOTHERMAL REACTION MICROCALORIMETRY; 3.1.1. The Heat of Mixing Reaction; 3.1.2. Mixing of Reagents in Comparable Volumes; 3.1.3. Isothermal Titration Microcalorimeter; 3.1.4. ITC Experiments; 3.1.5. Analysis of the ITC Data; 3.2. HEAT CAPACITY CALORIMETRY; 3.2.1. Technical Problems; 3.2.2. Differential Scanning Microcalorimeter; 3.2.3. Determination of the Partial Heat Capacity of Solute Molecules; 3.2.4. DSC Experiments 3.2.5. Determination of the Enthalpy of a Temperature-Induced Process3.2.6. Determination of the van't Hoff Enthalpy; 3.2.7. Multimolecular Two-State Transition; 3.2.8. Analysis of the Complex Heat Capacity Profile; 3.2.9. Correction for Components Refolding; 3.3. PRESSURE PERTURBATION CALORIMETRY; 3.3.1. Heat Effect of Changing Pressure; 3.3.2. Pressure Perturbation Experiment; REFERENCES; 4: MACROMOLECULES; 4.1. EVOLUTION OF THE CONCEPT; 4.2. PROTEINS; 4.2.1. Chemical Structure; 4.2.2. Physical Structure; 4.2.3. Restrictions on the Conformation of Polypeptide Chains 4.2.4. Regular Conformations of Polypeptide Chain Proteins4.3. HIERARCHY IN PROTEIN STRUCTURE; 4.3.1. Tertiary Structure of Proteins; 4.3.2. Quaternary Structure of Proteins; 4.4. NUCLEIC ACIDS; 4.4.1. Chemical Structure; 4.4.2. Physical Structure; REFERENCES; 5: THE α-HELIX AND α-HELICAL COILED-COIL; 5.1. THE α-HELIX; 5.1.1. Calorimetric Studies of α-Helix Unfolding-Refolding; 5.1.2. Analysis of the Heat Capacity Function; 5.2. α-HELICAL COILED-COILS; 5.2.1. Two-Stranded Coiled-Coils; 5.2.2. Three-Stranded Coiled-Coils; 5.3. α-HELICAL COILED-COIL PROTEINS; 5.3.1. Muscle Proteins 5.3.2. Myosin Rod5.3.3. Paramyosin; 5.3.4. Tropomyosin; 5.3.5. Leucine Zipper; 5.3.6. Discreteness of the Coiled-Coils; REFERENCES; 6: POLYPROLINE-II COILED-COILS; 6.1. COLLAGENS; 6.1.1. Collagen Superhelix; 6.1.2. Hydrogen Bonds in Collagen; 6.1.3. Stability of Collagens; 6.1.4. Role of Pyrrolidine Rings in Collagen Stabilization; 6.2. CALORIMETRIC STUDIES OF COLLAGENS; 6.2.1. Enthalpy and Entropy of Collagen Melting; 6.2.2. Correlation between Thermodynamic and Structural Characteristics of Collagens; 6.2.3. Role of Water in Maintaining the Collagen Structure 6.3. THERMODYNAMICS OF COLLAGENS |
| Record Nr. | UNINA-9910819988403321 |
|
Privalov Peter L
|
||
| Hoboken, N.J., : Wiley, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Modern tools for the synthesis of complex bioactive molecules [[electronic resource] /] / edited by Stellios Arseniyadis, Janine Cossy
| Modern tools for the synthesis of complex bioactive molecules [[electronic resource] /] / edited by Stellios Arseniyadis, Janine Cossy |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2012 |
| Descrizione fisica | 1 online resource (600 p.) |
| Disciplina | 547/.139 |
| Altri autori (Persone) |
ArseniyadisS (Stellios)
CossyJanine |
| Soggetto topico |
Biomolecules - Synthesis
Biochemistry |
| ISBN |
1-283-59891-4
9786613911360 1-118-34287-9 1-118-34288-7 1-118-34285-2 |
| Classificazione | SCI007000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MODERN TOOLS FOR THE SYNTHESIS OF COMPLEX BIOACTIVE MOLECULES; CONTENTS; FOREWORD; PREFACE; CONTRIBUTORS; CHAPTER 1: C-H FUNCTIONALIZATION: A NEW STRATEGY FOR THE SYNTHESIS OF BIOLOGICALLY ACTIVE NATURAL PRODUCTS; 1.1. INTRODUCTION; 1.2. PALLADIUM(0)-CATALYZED INTRAMOLECULAR DIRECT ARYLATION; 1.3. PALLADIUM(0)-CATALYZED INTRAMOLECULAR ALKENYLATION OF sp2 C-H BONDS; 1.4. PALLADIUM(0)-CATALYZED INTRAMOLECULAR ARYLATION OF sp3 C-H BONDS; 1.5. PALLADIUM(II)-MEDIATED INTRAMOLECULAR OXIDATIVE ALKENYLATION OF sp2 C-H BONDS
1.6. DIRECTING GROUP-ASSISTED PALLADIUM(II)- ENABLED CARBON-CARBON BOND FORMATION AT sp3 C-H BONDS1.7. PLATINUM(II)-MEDIATED ALKANE DEHYDROGENATION; 1.8. PALLADIUM(II)-ENABLED CARBON-OXYGEN BOND FORMATION AT sp3 C-H BONDS; 1.9. IRIDIUM-CATALYZED BORYLATION OF sp2 C-H BONDS; 1.10. RHODIUM(I)-CATALYZED INTRAMOLECULAR DIRECTED ALKYLATION OF sp2 C-H BONDS; 1.11. RHODIUM(III)-CATALYZED SYNTHESIS OF NITROGEN-CONTAINING HETEROCYCLES; 1.12. CONCLUSION; REFERENCES; CHAPTER 2: THE NEGISHI CROSS-COUPLING IN THE SYNTHESIS OF NATURAL PRODUCTS AND BIOACTIVE MOLECULES; 2.1. INTRODUCTION 2.2. SYNTHESIS OF NATURAL PRODUCTS 2.2.1. Synthesis of Polyenes; 2.2.2. Synthesis of Amino Acids and Macrocyclic Peptides; 2.2.3. Synthesis of Macrocycles; 2.2.4. Synthesis of Small Heterocycles; 2.3. LARGE-SCALE SYNTHESIS OF BIOLOGICALLY ACTIVE MOLECULES; 2.3.1. Nonsteroidal Ligand A-224817.0 1A; 2.3.2. Phosphodiesterase Inhibitor PDE472; 2.3.3. Reverse Transcriptase Inhibitor MIV-150; 2.3.4. B-Raf Kinase Inhibitors; 2.3.5. mGluR1 Antagonist; 2.4. CONCLUSION; REFERENCES; CHAPTER 3: METAL-CATALYZED C-HETEROATOM CROSS-COUPLING REACTIONS; 3.1. GENERAL INTRODUCTION 3.2. BUCHWALD-HARTWIG-TYPE REACTIONS 3.2.1. Introduction; 3.2.2. Mechanism; 3.2.3. Scope and Limitations; 3.2.4. Applications in the Synthesis of Complex Bioactive Molecules; 3.2.5. C-N Bond Formation; 3.2.6. C-S and C-O Bond Formation; 3.3. ULLMANN-TYPE REACTIONS; 3.3.1. Introduction; 3.3.2. Mechanism; 3.3.3. Scope and Limitations; 3.3.4. Applications in the Synthesis of Complex Bioactive Molecules; 3.3.5. C-N Bond Formation; 3.3.6. C-O Bond Formation; 3.4. MISCELLANEOUS; 3.4.1. Chan-Lam-Evans; 3.4.2. Iron/Copper-Mediated Methodologies; 3.4.3. Other Metals; 3.5. CONCLUSION; REFERENCES CHAPTER 4: GOLDEN OPPORTUNITIES IN THE SYNTHESIS OF NATURAL PRODUCTS AND BIOLOGICALLY ACTIVE COMPOUNDS 4.1. INTRODUCTION; 4.2. GOLD-CATALYZED FORMATION OF OXYGEN-CONTAINING HETEROCYCLES; 4.2.1. Cyclizations Leading to Furan and Pyran Derivatives; 4.2.2. Spiroketalizations; 4.2.3. Other Transformations; 4.3. GOLD-CATALYZED FORMATION OF NITROGEN-CONTAINING HETEROCYCLES; 4.3.1. Cyclizations Involving the Formation of a New C-N Bond; 4.3.2. Cyclizations Involving the Formation of a New C-C Bond; 4.4. GOLD-CATALYZED FORMATION OF CARBOCYCLES 4.4.1. Cyclizations Involving the Formation of a Single New C-C Bond |
| Record Nr. | UNINA-9910137616703321 |
| Hoboken, N.J., : Wiley, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Modern tools for the synthesis of complex bioactive molecules / / edited by Stellios Arseniyadis, Janine Cossy
| Modern tools for the synthesis of complex bioactive molecules / / edited by Stellios Arseniyadis, Janine Cossy |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2012 |
| Descrizione fisica | 1 online resource (600 p.) |
| Disciplina | 547/.139 |
| Altri autori (Persone) |
ArseniyadisS (Stellios)
CossyJanine |
| Soggetto topico |
Biomolecules - Synthesis
Biochemistry |
| ISBN |
1-283-59891-4
9786613911360 1-118-34287-9 1-118-34288-7 1-118-34285-2 |
| Classificazione | SCI007000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MODERN TOOLS FOR THE SYNTHESIS OF COMPLEX BIOACTIVE MOLECULES; CONTENTS; FOREWORD; PREFACE; CONTRIBUTORS; CHAPTER 1: C-H FUNCTIONALIZATION: A NEW STRATEGY FOR THE SYNTHESIS OF BIOLOGICALLY ACTIVE NATURAL PRODUCTS; 1.1. INTRODUCTION; 1.2. PALLADIUM(0)-CATALYZED INTRAMOLECULAR DIRECT ARYLATION; 1.3. PALLADIUM(0)-CATALYZED INTRAMOLECULAR ALKENYLATION OF sp2 C-H BONDS; 1.4. PALLADIUM(0)-CATALYZED INTRAMOLECULAR ARYLATION OF sp3 C-H BONDS; 1.5. PALLADIUM(II)-MEDIATED INTRAMOLECULAR OXIDATIVE ALKENYLATION OF sp2 C-H BONDS
1.6. DIRECTING GROUP-ASSISTED PALLADIUM(II)- ENABLED CARBON-CARBON BOND FORMATION AT sp3 C-H BONDS1.7. PLATINUM(II)-MEDIATED ALKANE DEHYDROGENATION; 1.8. PALLADIUM(II)-ENABLED CARBON-OXYGEN BOND FORMATION AT sp3 C-H BONDS; 1.9. IRIDIUM-CATALYZED BORYLATION OF sp2 C-H BONDS; 1.10. RHODIUM(I)-CATALYZED INTRAMOLECULAR DIRECTED ALKYLATION OF sp2 C-H BONDS; 1.11. RHODIUM(III)-CATALYZED SYNTHESIS OF NITROGEN-CONTAINING HETEROCYCLES; 1.12. CONCLUSION; REFERENCES; CHAPTER 2: THE NEGISHI CROSS-COUPLING IN THE SYNTHESIS OF NATURAL PRODUCTS AND BIOACTIVE MOLECULES; 2.1. INTRODUCTION 2.2. SYNTHESIS OF NATURAL PRODUCTS 2.2.1. Synthesis of Polyenes; 2.2.2. Synthesis of Amino Acids and Macrocyclic Peptides; 2.2.3. Synthesis of Macrocycles; 2.2.4. Synthesis of Small Heterocycles; 2.3. LARGE-SCALE SYNTHESIS OF BIOLOGICALLY ACTIVE MOLECULES; 2.3.1. Nonsteroidal Ligand A-224817.0 1A; 2.3.2. Phosphodiesterase Inhibitor PDE472; 2.3.3. Reverse Transcriptase Inhibitor MIV-150; 2.3.4. B-Raf Kinase Inhibitors; 2.3.5. mGluR1 Antagonist; 2.4. CONCLUSION; REFERENCES; CHAPTER 3: METAL-CATALYZED C-HETEROATOM CROSS-COUPLING REACTIONS; 3.1. GENERAL INTRODUCTION 3.2. BUCHWALD-HARTWIG-TYPE REACTIONS 3.2.1. Introduction; 3.2.2. Mechanism; 3.2.3. Scope and Limitations; 3.2.4. Applications in the Synthesis of Complex Bioactive Molecules; 3.2.5. C-N Bond Formation; 3.2.6. C-S and C-O Bond Formation; 3.3. ULLMANN-TYPE REACTIONS; 3.3.1. Introduction; 3.3.2. Mechanism; 3.3.3. Scope and Limitations; 3.3.4. Applications in the Synthesis of Complex Bioactive Molecules; 3.3.5. C-N Bond Formation; 3.3.6. C-O Bond Formation; 3.4. MISCELLANEOUS; 3.4.1. Chan-Lam-Evans; 3.4.2. Iron/Copper-Mediated Methodologies; 3.4.3. Other Metals; 3.5. CONCLUSION; REFERENCES CHAPTER 4: GOLDEN OPPORTUNITIES IN THE SYNTHESIS OF NATURAL PRODUCTS AND BIOLOGICALLY ACTIVE COMPOUNDS 4.1. INTRODUCTION; 4.2. GOLD-CATALYZED FORMATION OF OXYGEN-CONTAINING HETEROCYCLES; 4.2.1. Cyclizations Leading to Furan and Pyran Derivatives; 4.2.2. Spiroketalizations; 4.2.3. Other Transformations; 4.3. GOLD-CATALYZED FORMATION OF NITROGEN-CONTAINING HETEROCYCLES; 4.3.1. Cyclizations Involving the Formation of a New C-N Bond; 4.3.2. Cyclizations Involving the Formation of a New C-C Bond; 4.4. GOLD-CATALYZED FORMATION OF CARBOCYCLES 4.4.1. Cyclizations Involving the Formation of a Single New C-C Bond |
| Record Nr. | UNINA-9910819593103321 |
| Hoboken, N.J., : Wiley, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Natural products in chemical biology [[electronic resource] /] / edited by Natanya Civjan
| Natural products in chemical biology [[electronic resource] /] / edited by Natanya Civjan |
| Edizione | [1st edition] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2012 |
| Descrizione fisica | 1 online resource (437 p.) |
| Disciplina | 572 |
| Altri autori (Persone) | CivjanNatanya |
| Soggetto topico |
Biochemistry
Biological products Natural products |
| ISBN |
1-283-94339-5
1-118-39182-9 1-118-39181-0 |
| Classificazione | SCI007000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
NATURAL PRODUCTSIN CHEMICAL BIOLOGY; CONTENTS; Preface; Contributors; PART I CHEMICAL DIVERSITY OF NATURAL PRODUCTS; 1 Plant Natural Products; 2 Marine Natural Products; 3 Microbial Natural Products; PART II BIOSYNTHESIS OF NATURAL PRODUCTS; 4 Nonribosomal Peptides; 5 Plant Terpenoids; 6 Polyketides in Fungi; 7 Modular Polyketide Synthases; 8 Polyketide Polyethers; 9 Alkaloids; 10 Cofactors; 11 Antibiotics; PART III NATURAL PRODUCTS IN MEDICINE; 12 Pharmaceuticals: Natural Products and Natural ProductModels; 13 Natural Products as Anticancer Agents
14 Plant-Derived Natural Products Research in Drug DiscoveryIndex |
| Record Nr. | UNINA-9910130591803321 |
| Hoboken, N.J., : Wiley, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Natural products in chemical biology / / edited by Natanya Civjan
| Natural products in chemical biology / / edited by Natanya Civjan |
| Edizione | [1st edition] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2012 |
| Descrizione fisica | 1 online resource (437 p.) |
| Disciplina | 572 |
| Altri autori (Persone) | CivjanNatanya |
| Soggetto topico |
Biochemistry
Biological products Natural products |
| ISBN |
1-283-94339-5
1-118-39182-9 1-118-39181-0 |
| Classificazione | SCI007000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
NATURAL PRODUCTSIN CHEMICAL BIOLOGY; CONTENTS; Preface; Contributors; PART I CHEMICAL DIVERSITY OF NATURAL PRODUCTS; 1 Plant Natural Products; 2 Marine Natural Products; 3 Microbial Natural Products; PART II BIOSYNTHESIS OF NATURAL PRODUCTS; 4 Nonribosomal Peptides; 5 Plant Terpenoids; 6 Polyketides in Fungi; 7 Modular Polyketide Synthases; 8 Polyketide Polyethers; 9 Alkaloids; 10 Cofactors; 11 Antibiotics; PART III NATURAL PRODUCTS IN MEDICINE; 12 Pharmaceuticals: Natural Products and Natural ProductModels; 13 Natural Products as Anticancer Agents
14 Plant-Derived Natural Products Research in Drug DiscoveryIndex |
| Record Nr. | UNINA-9910818804503321 |
| Hoboken, N.J., : Wiley, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Plant metabolism and biotechnology / / edited by Hiroshi Ashihara, Alan Crozier, Atsushi Komamine
| Plant metabolism and biotechnology / / edited by Hiroshi Ashihara, Alan Crozier, Atsushi Komamine |
| Pubbl/distr/stampa | Chichester, West Sussex, : Wiley, 2011 |
| Descrizione fisica | 1 online resource (422 p.) |
| Disciplina | 660.6 |
| Altri autori (Persone) |
AshiharaHiroshi
CrozierAlan KomamineAtsushi <1929-> |
| Soggetto topico |
Plants - Metabolism
Plant biotechnology |
| ISBN |
1-283-40532-6
9786613405326 1-119-99323-7 1-119-99132-3 1-119-99131-5 |
| Classificazione | SCI007000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Plant Metabolism and Biotechnology; Contents; List of Contributors; Preface; 1 Biosynthesis and Metabolism of Starch and Sugars; 1.1 Introduction; 1.2 Carbon Partitioning in Mesophyll Cells; 1.3 Sucrose Biosynthesis in Source Leaves; 1.3.1 Regulatory Enzymes of the Pathway; 1.4 Starch Metabolism in Source Leaves; 1.4.1 Starch Synthesis within the Chloroplast; 1.4.2 Starch Breakdown in Leaves and Metabolism of its Degradation Products in the Cytosol; 1.5 Sucrose to Starch Conversion in Storage Organs; 1.6 Metabolic Engineering of Carbohydrate Metabolism; 1.6.1 Increasing Starch Content
1.6.2 Altering Starch Quality1.7 Engineering Soluble Sugars; 1.8 Production of Novel Carbohydrates in Transgenic Plants; 1.9 Network Analysis of Carbohydrate Metabolism; Acknowledgements; References; 2 Lipid Biosynthesis; 2.1 Introduction; 2.2 Fatty Acid Synthesis; 2.3 Fatty Acid Desaturases; 2.3.1 -9 Desaturases; 2.3.2 -12 Desaturases; 2.3.3 -3 Desaturases; 2.4 Lipid Signals; 2.5 Algae; 2.6 Membrane Synthesis; 2.7 TAG Biosynthesis; 2.8 Genetic Engineering of Oilseed for Industrial Uses; 2.9 Plant Oils as a Renewable Resource; Acknowledgements; References; 3 Symbiotic Nitrogen Fixation 3.1 Nitrogen Fixing Organisms and the Nitrogenase System3.1.1 Nitrogen Fixing Microorganisms; 3.1.2 The Nitrogenase Complex; 3.1.3 Nif Genes and Regulation; 3.2 Symbiotic Nodule Formation in Legume Plants; 3.2.1 Infection and the Nodulation Process; 3.2.2 Nod Factors, Early Symbiotic Signalling and the Rhizobial Infection Process; 3.3 Mutual Interactions between Host Cells and Bacteroids in Legume Nodules; 3.3.1 Differentiation of Rhizobia into Bacteroids; 3.3.2 Protection of the Nitrogenase System from Oxygen in Root Nodules 3.3.3 Metabolite Exchange between the Plant Cell Cytosol and Bacteroids3.4 Molecular Genetic Approaches to the Host Regulation of Nitrogen Fixation; 3.4.1 The Fix- Mutants: Host Legume-Determined Ineffective Nodules; 3.4.2 Metabolic Partnerships Unveiled by Fix- Mutants; 3.4.3 Premature Senescence in Fix- Nodules and Symbiosome Organisation; Acknowledgements; References; 4 Sulfur Metabolism; 4.1 Introduction; 4.2 Sulfate Transport; 4.2.1 Sulfate Transport Mechanisms; 4.2.2 Sulfate Uptake System; 4.2.3 Transport of Sulfate from Roots to Shoots; 4.2.4 Subcellular Transport of Sulfate 4.2.5 Redistribution of Sulfur4.2.6 Regulation of Sulfate Uptake; 4.3 Sulfate Reduction; 4.3.1 ATP Sulfurylase; 4.3.2 APS Reductase; 4.3.3 APS Kinase; 4.3.4 Sulfite Reductase; 4.3.5 Regulation of Sulfate Reduction; 4.4 Cysteine Biosynthesis; 4.4.1 O-Acetylserine(thiol)lyase; 4.4.2 Serine Acetyltransferase; 4.4.3 Cysteine Synthase Complex; 4.5 Methionine Biosynthesis; 4.5.1 Biosynthetic Pathways; 4.5.2 Regulation of Methionine Biosynthesis; 4.6 Regulators for Coordination of Sulfur Metabolism; 4.6.1 Transcriptional Regulators; 4.6.2 MicroRNA-395; 4.6.3 OAS-Mediated Regulation 4.6.4 Outlook for Application |
| Record Nr. | UNINA-9910130878003321 |
| Chichester, West Sussex, : Wiley, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
