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Primary Intracranial Tumors / / edited by Erasmo Barros Da Silva Junior and Jerônimo Buzetti Milano
| Primary Intracranial Tumors / / edited by Erasmo Barros Da Silva Junior and Jerônimo Buzetti Milano |
| Pubbl/distr/stampa | London, United Kingdom : , : IntechOpen, , 2019 |
| Descrizione fisica | 1 online resource (140 pages) |
| Disciplina | 616.99481 |
| Soggetto topico | Intracranial tumors |
| ISBN |
1-83962-080-3
1-78985-406-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910317957103321 |
| London, United Kingdom : , : IntechOpen, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Principles of Neuro-Oncology : Brain & Skull Base / / edited by Alejandro Monroy-Sosa, Srikant S. Chakravarthi, Jaime G. de la Garza-Salazar, Abelardo Meneses Garcia, Amin B. Kassam
| Principles of Neuro-Oncology : Brain & Skull Base / / edited by Alejandro Monroy-Sosa, Srikant S. Chakravarthi, Jaime G. de la Garza-Salazar, Abelardo Meneses Garcia, Amin B. Kassam |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 |
| Descrizione fisica | 1 online resource (XIII, 982 p. 500 illus., 425 illus. in color.) |
| Disciplina | 616.99481 |
| Soggetto topico |
Oncology
Neurology Cancer—Treatment Nervous system—Surgery Cancer Therapy Neurosurgery |
| ISBN | 3-030-54879-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Introduction -- Part 1: Tumor Biology -- 2. Epidemiology -- 3. Molecular Biomarkers in Tumors -- 4. Molecular Biomarkers in Brain Metastasis -- 5. Pathology Classification -- Part 2: Planning -- 6. Microsurgical Anatomy of the Cranial Base and the White Matter Tracts (3D) -- 7. Microsurgical Anatomy of the Brainstem -- 8. Advances in Neuroimaging -- 9. DTI: planning for skull base and intra-axial tumors approaches -- 10. Neurological Examination -- 11. Neuro-Psychiatric Examination -- 12. Embolization of the Cranial Base Tumors -- Part 3:RT -- 13. Whole Brain Radiation -- 14. Radiosurgery (LINAC) -- Part 4: Chemotherapy -- 15. Chemotherapy -- 16. Intratumoral Chemotehrapy -- 17. Genetic Therapy ( Gliomas) -- Part 5: Surgery -- 18. Surgical Radial Corridors Dorsal and Ventral Approaches to the Cranial Base) -- 19. Parafascicular Surgery (Chassis) -- 20. Craniofacial Approaches -- 21. Early experience with the ROVOT-m in Neurosurgery -- 22. Awake Surgery in Brain Tumors -- 23. Transclival Approaches -- 24. Surgery in Spine Tumor -- 25. Infratemporal Fossa and Pharapharyngeal Space Surgery -- 26. 360 around of the Craniocervical Junction -- 27. Neuroendoscopy -- 28. 360 around of the Orbit -- Part 6: Tumors -- 29. Surgery in Gliomas -- 30. Surgery in Meningiomas of the Anterior Cranial Base (EEA) -- 31. Surgery in Meningiomas of the Anterior Cranial Base (Open) -- 32. Surgery in Meningiomas of the Middle Cranial Base -- 33. Surgery in Meningiomas of the Posterior Cranial Base -- 34. Surgery in CPA angle -- 35. Surgery for Craniopharyngioma -- 36. Pituitary Surgery (EEA and Open) -- 37. Yugular Schawannomas Surgery -- 38. Surgery of the Intraventricular Tumors -- 39. Brain Metastasis Surgery -- 40. Surgery of Esthesioneuroblastoma -- 41. Chordomas Surgery -- 42. Brainstem Surgery. |
| Record Nr. | UNINA-9910484022903321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Radiobiology of Glioblastoma : Recent Advances and Related Pathobiology / / edited by Luigi Pirtoli, Giovanni Luca Gravina, Antonio Giordano
| Radiobiology of Glioblastoma : Recent Advances and Related Pathobiology / / edited by Luigi Pirtoli, Giovanni Luca Gravina, Antonio Giordano |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Humana, , 2016 |
| Descrizione fisica | 1 online resource (XX, 305 p. 49 illus., 39 illus. in color.) |
| Disciplina | 616.99481 |
| Collana | Current Clinical Pathology |
| Soggetto topico |
Pathology
Oncology Oncology |
| ISBN | 3-319-28305-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction and Background -- The “Radio-resistance” of Glioblastoma in the Clinical Setting, and the Present Therapeutic Options -- Radiobiological Hints from Clinical Studies -- Chemo-radiotherapy: Radiation Total Dose and Fractionation -- Clinical Evidence and Radiobiological Background of Particle Radiation Therapy -- Mathematical Modeling of Radiobiological Parameters from Clinical Studies -- Clinical, Pathology and Molecular Prognostic Parameters of Response to Chemo- and Radiotherapy from Clinical Series -- Radiation Tolerance of Normal Brain: QUANTEC 2010 and Beyond -- Basic Knowledge of Glioblastoma Radiobiology -- Molecular Radiobiology and Mathematical Modeling -- Genetic and Epigenetic Determinants in Tumor Initiation and Progression -- Tumor Microenvironment -- Cell Death Pathways, with Special Regard to Ionizing Radiation and Temozolomide Therapy -- mi-RNA Manipulation in Modifying Radiation Sensitivity in Glioblastoma Models -- Glioma Stem-like Cells and Radiation Resistance -- Hypoxia and Radiation Resistance -- Invasiveness and Radiation Failures -- Nanoparticle Technology for Research Radiobiology -- The Molecular Classification of Glioblastoma as a Translational Instrument -- Translational Perspectives for Gene Therapy -- Pre-Clinical Models of Glioblastoma in Radiobiology: Evolving Protocols and Research Methods -- From Molecular to Clinical Radiation Biology -- Perspectives of the Large Data-Bases and Ontologic Models of Correlation of Pre-clinical and Clinical Results -- Conclusive Remarks and Perspectives for Future Research. |
| Record Nr. | UNINA-9910254545503321 |
| Cham : , : Springer International Publishing : , : Imprint : Humana, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Surgery of the Cerebellopontine Angle / / Nicholas C. Bambakidis, Cliff A. Megerian, and Robert F. Spetzler, editors
| Surgery of the Cerebellopontine Angle / / Nicholas C. Bambakidis, Cliff A. Megerian, and Robert F. Spetzler, editors |
| Edizione | [Second edition.] |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (408 pages) |
| Disciplina | 616.99481 |
| Soggetto topico |
Cerebellopontile angle - Tumors
Cerebellopontile angle - Endoscopic surgery |
| ISBN | 3-031-12507-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- Contributors -- Part I: Foundations for Treatment -- 1: Historical Perspectives -- History of Vestibular Schwannoma Surgery -- Otology and the Operating Microscope -- Modern Surgery in the Cerebellopontine Angle -- Neurovascular Decompression -- Radiosurgery -- Conclusions -- References -- 2: Microsurgical Anatomy of the Cerebellopontine Angle and Its Suboccipital Retromastoid Approaches -- Relationships Between the Cranial Surface and the CPA -- Osseous and Muscular Relationships, Transverse and Sigmoid Sinuses, and External Surgical Landmarks -- Relationships Among CPA Nerves and Brainstem -- CPA Upper Neurovascular Complex -- Middle Neurovascular Complex of the CPA -- Lower Neurovascular Complex of the CPA -- Summary -- References -- 3: Radiology -- Technical Considerations -- Screening Studies -- General Classification of Lesions -- Extraaxial Lesions -- Vascular Lesions -- Extradural Lesions -- Intraaxial Lesions -- Angiography -- Preoperative and Follow-Up Imaging -- Preoperative Imaging of Vestibular Schwannomas -- Follow-Up Assessment After Treatment of Vestibular Schwannomas -- Imaging Pitfalls and Pseudomasses -- References -- 4: Neurology -- Anatomy -- Etiologies -- Clinical Manifestations -- Neurological Examination of the CPA -- Additional Testing -- Brainstem Syndromes -- References -- Part II: Surgical Approaches -- 5: Approaches to the Cerebellopontine Angle -- Introduction -- Retrosigmoid Approach -- Surgical Technique -- Transpetrosal Approaches -- Retrolabyrinthine Approach -- Translabyrinthine Approach -- Transcochlear Approach -- Middle Fossa Approach -- Surgical Technique -- Extended Middle Fossa Approach -- Endoscopic Approach -- Neuromonitoring and Anesthetic Considerations -- Facial Nerve Monitoring -- Vestibulocochlear Nerve Monitoring -- Glossopharyngeal and Vagus Nerve Monitoring.
Summary -- References -- 6: Combined Surgical Approaches -- General Considerations -- Transpetrosal Approaches -- Combined Open Approaches -- Endoscopic Endonasal Approach to the Petroclival Region -- Endoscopic Endonasal Approach Considerations -- Surgical Decision-Making -- References -- 7: Functional Surgery of the Cerebellopontine Angle -- Vestibular Neurectomy -- Clinical Material and Methods -- Operative Technique for Vestibular Neurectomy -- Outcomes of Vestibular Neurectomy -- Advantages and Disadvantages of Different Approaches for Vestibular Neurectomy -- Neurectomy of the Nervus Intermedius -- Case Report -- Diagnosis of Geniculate Neuralgia -- Functional Anatomy -- Neurectomy of the Glossopharyngeal Nerve -- Natural History and Clinical Manifestations of Glossopharyngeal Neuralgia -- Functional Anatomy -- Differential Diagnosis -- Treatment Options -- Preoperative Preparation -- Patient Positioning -- Operative Technique -- Microvascular Decompression -- Case Report: Microvascular Decompression for Tinnitus -- Authors' Experience: Microvascular Decompression for Trigeminal Neuralgia or Hemifacial Spasm -- Endoscopy as a Surgical Adjunct During Microvascular Decompression -- Auditory Brainstem Implantation -- Translabyrinthine Approach -- Retrosigmoid Approach -- Authors' Clinical Experience -- Highlights of Auditory Brainstem Implantation -- Summary and Conclusions -- References -- 8: Endoscopy in the Cerebellopontine Angle -- Equipment -- Overview of Endoscopic Techniques -- Operative Technique -- Avoiding Complications with the Endoscope -- Specific Applications of the Endoscope in the CPA: Cranial Nerve Decompression -- Trigeminal Neuralgia -- Hemifacial Spasm -- Glossopharyngeal Neuralgia -- Specific Applications of the Endoscope in the CPA: CPA Masses -- Vestibular Schwannoma -- Meningioma -- Epidermoid -- Arachnoid Cysts. Conclusion -- References -- Part III: Vestibular Schwannomas -- 9: Biology and Genetics of Vestibular Schwannomas in Tumors of the Cerebellopontine Angle -- Background -- The NF2 Gene -- Structure and Function of the NF2 Protein, Merlin -- NF2 Mutations and Their Clinical Correlation -- Merlin Acts as a Tumor Suppressor -- Molecular Roles of the Merlin Tumor Suppressor and Consequence of Its Loss in Vestibular Schwannomas -- Merlin and CD44-Mediated Contact Inhibition of Cellular Proliferation -- Merlin-Rac1 Mediated Cytoskeletal Interactions -- Merlin Activates the Mammalian Hippo Pathway to Induce Growth Arrest -- Merlin Inhibits the Mammalian Target of Rapamycin Pathway -- Additional Merlin-Mediated Pathways -- Epigenetic Alterations in Vestibular Schwannomas -- Histone Modifications and the Role of Histone Deacetylase Inhibitors -- Vascular Endothelial Growth Factor in VS -- Bench to Bedside: Molecular Targets of VS Therapy -- Summary -- References -- 10: Treatment Options for Acoustic Neuroma, Including Stereotactic Radiosurgery -- Introduction -- Observation -- Stereotactic Radiation and Radiosurgery -- Stereotactic Radiosurgery -- Tumor Control Rates -- Hearing Preservation -- Cranial Nerve Function -- Fractionated Radiotherapy -- Comparing Radiosurgery and Radiotherapy -- Proton Beam Therapy -- Risk of Secondary Malignancy -- Summary -- Microsurgery -- Hearing Results -- Facial Nerve Outcomes -- Cerebrospinal Fluid Leakage -- Patient Reported Quality of Life -- Conclusions -- References -- 11: Translabyrinthine Approach -- Preoperative Evaluation -- Patient Selection -- Surgical Procedure -- Tumor Dissection -- Complications -- Outcomes -- Postoperative Care -- Conclusions -- References -- 12: Hearing Rehabilitation Following Acoustic Neuroma Surgery -- Unilateral Hearing Loss -- Hearing Rehabilitation -- Contralateral Routing of Signal. Osseointegrated Hearing Implants -- Auditory Brainstem Implants -- Cochlear Implantation -- References -- 13: Acoustic Neuroma Surgery: Retrosigmoid Techniques -- Pathology and Pathophysiology -- Investigation -- Audiometry -- Classification -- Definition of Success -- Auditory Brainstem Responses -- Otoacoustic Emissions -- Vestibular Testing -- Radiology -- MRI Screening: When to Do It? -- Imaging Characteristics -- Complications -- Operative Techniques -- Retrosigmoid Approach -- Patient Position and Monitoring -- Incision -- Soft Tissue Dissection -- Craniotomy -- Dural Opening -- Retraction -- Identification of Nerves at Brainstem -- Removal of CPA Tumor -- Opening the Posterior Wall of the IAC -- Removal of Intracanalicular Tumor -- Closure -- Microsurgical Dissection -- Intraoperative Monitoring -- Hearing Results -- Which Approach? -- Follow-Up and Long-Term Outcomes -- Imaging -- Hearing -- Long-Term Risk of Recurrence -- References -- 14: Acoustic Neuroma Surgery: Middle Fossa Approach -- Introduction -- Surgical Candidacy -- Surgical Technique -- Preoperative Preparation -- Surgical Technique -- Postoperative Care -- Complications and Outcomes -- Conclusion -- References -- 15: Complications and Cranial Nerve Rehabilitation -- Cerebrospinal Fluid Leak and Meningitis -- Vascular Complications -- Venous Sinus Thrombosis -- Cranial Nerve Dysfunction -- Vestibular Dysfunction -- Facial Nerve -- Delayed Facial Paralysis -- Facial Paralysis and Eye Complications -- Lower Cranial Nerves -- Headache -- Conclusion -- References -- 16: Facial Reanimation -- Anatomy of Facial Nerve -- Nerve Injury Classification -- First-Degree Injury -- Second-Degree Injury -- Third-Degree Injury -- Fourth-Degree Injury -- Fifth-Degree Injury -- Nerve Repair and Nerve Grafting -- Nerve Grafting -- Facial Reanimation -- Nerve Substitution Techniques. Hypoglossal-Facial Transfer (Cranial Nerve XII-VII Crossover) -- Surgical Technique -- Trigeminal-to-Facial Nerve Transfer -- Surgical Technique -- Cranial Nerve VII-VII Cross-Facial Grafting -- Surgical Technique -- Regional Muscle Transfer Techniques -- Temporalis Muscle Transfer -- Surgical Technique -- Other Regional Muscle Transfers -- Free-Muscle Transfer -- Surgical Technique -- Static and Adjunctive Facial Reanimation -- Summary -- References -- 17: Hearing and Surgical Considerations in Neurofibromatosis Type 2 -- Diagnosis -- Genetics -- Vestibular Schwannomas -- Schwannomas Involving Other Cranial Nerves -- Meningiomas -- Collision Tumors -- Ependymomas -- Ocular Findings -- Surgical Management of Vestibular Schwannomas and Hearing Rehabilitation in NF2 -- Observation Without Surgical Intervention -- Middle Fossa Craniotomy with Decompression of the IAC -- Hearing Preservation Surgery with Total Tumor Removal -- Retrosigmoid Craniotomy with Partial Tumor Removal -- Nonhearing Preservation Surgery with Total Tumor Removal -- Hearing Rehabilitation Via an ABI or CI -- Radiation Therapy for NF2 -- Surgical Management of Other Tumors in NF2 -- Medical Management of NF2 -- Conclusion -- References -- 18: Prevention and Management of CSF Leakage Postoperatively -- Introduction -- Overall Rates -- Preoperative Issues -- Translabyrinthine Approach -- Retrosigmoid Approaches -- Middle Fossa Approach -- Other Approaches -- Management Options -- Recalcitrant Cases -- Conclusion -- References -- Part IV: Nonschwannomatous Lesions of the CPA -- 19: Temporal Bone Neoplasms -- Differential Diagnosis -- Temporal Bone Paragangliomas -- Pathology -- Clinical Manifestations -- Classification Schemes -- Operative Management -- Radiotherapy -- Endolymphatic Sac Tumors -- Pathology -- ELST and VHL -- Clinical Manifestations -- Diagnosis -- Treatment. Hemangiomas of the Geniculate Ganglion and Internal Auditory Canal. |
| Record Nr. | UNINA-9910637729803321 |
| Cham, Switzerland : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumors of the Central Nervous System : Primary and Secondary / / Lee Roy Morgan, editor
| Tumors of the Central Nervous System : Primary and Secondary / / Lee Roy Morgan, editor |
| Pubbl/distr/stampa | [Place of publication not identified] : , : InTech, , [2014] |
| Descrizione fisica | 1 online resource (272 pages) : illustrations |
| Disciplina | 616.99481 |
| Soggetto topico | Central nervous system - Tumors |
| ISBN |
953-51-7211-5
953-51-1576-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tumors of the central nervous system |
| Record Nr. | UNINA-9910136333303321 |
| [Place of publication not identified] : , : InTech, , [2014] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumors of the Central Nervous System, Volume 11 [[electronic resource] ] : Pineal, Pituitary, and Spinal Tumors / / edited by M.A. Hayat
| Tumors of the Central Nervous System, Volume 11 [[electronic resource] ] : Pineal, Pituitary, and Spinal Tumors / / edited by M.A. Hayat |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (396 p.) |
| Disciplina | 616.99481 |
| Collana | Tumors of the Central Nervous System |
| Soggetto topico |
Cancer research
Oncology Medicine Cancer Research Oncology Biomedicine, general |
| ISBN | 94-007-7037-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface. I Imaging -- An introduction to brain tumor imaging.-Molecular imaging of brain tumors -- Use of 11c-4dst-pet for imaging of human brain tumors. II Glioma and glioblastoma -- Diffusion tensor magnetic resonance imaging-based tractography for glioma surgery -- Angiocentric glioma, pilomyxoid astrocytoma, and Pituicytoma: new entities in the world health organization classification -- Diffuse intrinsic pontine gliomas in children: treatment (an Update) -- Gliomatosis cerebri: implications of genetic findings -- Impact of bevacizumab chemotherapy on glioblastomas -- Glioblastoma microvesicles transport rna and proteins Promoting tumor growth -- Microrna in the pathophysiology of glioblastoma -- Surgical management of incidental low-grade gliomas. III Stereotactic radiosurgery -- Stereotactic radiosurgery for the treatment of brain metastases -- Local control of low-volume brain metastases using stereotactic radiosurgery -- Tumor seeding after stereotactic brain biopsy -- Intracranial stereotactic radiosurgery in high risk patients with metastases from radioresistant primary tumors -- Brain metastases: treatment with stereotactic iodine-125 brachytherapy -- Stereotactic radiosurgery for skull base meningiomas. IV Spinal cord tumors -- Pediatric spinal cord tumors -- Radiosurgery for intramedullary spinal cord tumors -- Novalis spinal radiosurgery -- Etiology and outcomes of pediatric spinal cord tumors. V Meningioma -- Selection of elderly meningioma patients for surgery using a Clinical-radiological grading system as a predictor of outcome -- Cranial meningioma in neurofibromatosis type 2 patients: role of mutations -- Classification of meningioma using immunogenic antigens -- Treatment of benign meningiomas using radiosurgery -- Necrotic rhabdoid meningiomas: histopathological diagnosis. VI Schwannomas. 27 Multiple schwannomas: diagnosis and treatment -- Treatment of patients with vestibular schwanommas using gamma knife radiosurgery -- Schwannomas in the craniocervical region: complete surgical removal -- Cranial base surgery of hypoglossal schwannomas. Index. |
| Record Nr. | UNINA-9910300334703321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Tumors of the Central Nervous System, Volume 14 [[electronic resource] ] : Glioma, Meningioma, Neuroblastoma, and Spinal Tumors / / edited by M.A. Hayat
| Tumors of the Central Nervous System, Volume 14 [[electronic resource] ] : Glioma, Meningioma, Neuroblastoma, and Spinal Tumors / / edited by M.A. Hayat |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (132 p.) |
| Disciplina | 616.99481 |
| Collana | Tumors of the Central Nervous System |
| Soggetto topico |
Cancer research
Oncology Neurosciences Cancer Research Oncology |
| ISBN | 94-017-7224-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Angiocentric Glioma, Pilomyxoid Astrocytoma, and Pituicytoma: New Entities in the World Health Organization Classification -- Pediatric Low-Grade Gliomas: Diagnosis, Treatment, and Future Directions -- Kringle 1-5 Reduces Growth of Malignant Gliomas in Rats -- Fluorescence Guided Resection and Photodynamic Therapy in Meningiomas -- Classification of Meningiomas in the Cerebellopontine Angle -- Postoperative Cerebral Hyperemia----Pathophysiology and Clinical Concerns -- Role of N-MYC on Microrna Expression In Neuroblastoma -- Evidence-Based Approach for the Management of Cerebral Metastases From Lung Adenocarcinoma -- Intramedullary Spinal Cord Tumors: Long-Term Follow-up After Surgery -- Index. |
| Record Nr. | UNINA-9910300164903321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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