top

  Info

  • Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.

  Info

  • Utilizzare questo link per rimuovere la selezione effettuata.
Small Molecules in Oncology [[electronic resource] /] / edited by Uwe M. Martens
Small Molecules in Oncology [[electronic resource] /] / edited by Uwe M. Martens
Edizione [2nd ed. 2014.]
Pubbl/distr/stampa Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014
Descrizione fisica 1 online resource (418 p.)
Disciplina 616.994071
Collana Recent Results in Cancer Research
Soggetto topico Oncology  
Hematology
Cancer research
Oncology
Cancer Research
ISBN 3-642-54490-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Imatinib Mesylate -- Erlotinib -- Axitinib (AG-013736) -- Lapatinib -- Sorafenib -- Sunitinib -- Dasatinib -- Nilotinib -- Bosutinib -- Decitabine -- Azacytidine/Azacitidine -- Bortezomib -- Temsirolimus -- Danusertib -- Vismodegib -- Everolimus -- Vemurafenib -- Vandetanib -- Trametinib -- Dabrafenib -- Ponatinib -- Regorafenib -- Cabozantinib -- Revlimid -- Ibrutinib -- Qizartinib -- Ruxolitinib -- Carfilzomib -- Afitinib.
Record Nr. UNINA-9910300336403321
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Some industrial chemicals [[electronic resource]]
Some industrial chemicals [[electronic resource]]
Pubbl/distr/stampa Lyon, France, : IARC
Descrizione fisica 1 online resource (573 p.)
Disciplina 615.902
616.994071
Collana IARC monographs on the evaluation of carcinogenic risks to humans
Soggetto topico Carcinogens
Industrial toxicology
Soggetto genere / forma Electronic books.
ISBN 1-281-77600-9
92-832-1584-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910453420303321
Lyon, France, : IARC
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
STAT Inhibitors in Cancer / / edited by Alister C. Ward
STAT Inhibitors in Cancer / / edited by Alister C. Ward
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Humana, , 2016
Descrizione fisica 1 online resource (VII, 195 p. 11 illus. in color.)
Disciplina 616.994071
Collana Cancer Drug Discovery and Development
Soggetto topico Cancer research
Cancer Research
ISBN 9783319429496
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto STATs in Health and Disease -- STAT Proteins in Cancer -- Translating STAT Inhibitors from the Lab to the Clinic -- Historical Development of STAT3 Inhibitors and Early Results in Clinical Trials -- STAT3 Inhibitors in Cancer: A Comprehensive Update -- Targeting Upstream Janus Kinases -- Inhibitors of Upstream Inducers of STAT Activation.
Record Nr. UNINA-9910254539403321
Cham : , : Springer International Publishing : , : Imprint : Humana, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The Steam cell microenvironment and its role in regenerative medicine and cancer pathogenisis / / editors, Cristian Pablo Pennisi, Mayuri Sinha Prasad, Pranela Rameshwar
The Steam cell microenvironment and its role in regenerative medicine and cancer pathogenisis / / editors, Cristian Pablo Pennisi, Mayuri Sinha Prasad, Pranela Rameshwar
Pubbl/distr/stampa Alsbjergvej, Gistrup, Denmark ; ; Delft, The Netherlands : , : River Publishers, , 2017
Descrizione fisica 1 online resource (144 pages) : illustrations (some color), tables
Disciplina 616.994071
Collana River Publishers Series in Research and Business Chronicles: Biotechnology and Medicine
Soggetto topico Carcinogenesis
Carcinogens
Regenerative medicine
Soggetto genere / forma Electronic books.
ISBN 87-93519-00-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910466358103321
Alsbjergvej, Gistrup, Denmark ; ; Delft, The Netherlands : , : River Publishers, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The stem cell microenvironment and its role in regenerative medicine and cancer pathogenisis / / editors, Cristian Pablo Pennisi, Mayuri Sinha Prasad, Pranela Rameshwar
The stem cell microenvironment and its role in regenerative medicine and cancer pathogenisis / / editors, Cristian Pablo Pennisi, Mayuri Sinha Prasad, Pranela Rameshwar
Edizione [First edition.]
Pubbl/distr/stampa Gistrup, Denmark ; ; Delft, The Netherlands : , : River Publishers, , 2017
Descrizione fisica 1 online resource (144 pages) : illustrations (some color), tables
Disciplina 616.994071
Collana River Publishers series in research and business chronicles: biotechnology and medicine
Soggetto topico Carcinogenesis
Carcinogens
Regenerative medicine
ISBN 1-00-333977-8
1-003-33977-8
1-000-79411-3
1-000-79525-X
87-93519-00-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover -- Half Title Page -- RIVER PUBLISHERS SERIES IN RESEARCH AND BUSINESS CHRONICLES: BIOTECHNOLOGY AND MEDICINE -- Full Title - The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis -- Copyright Page -- Contents -- Preface -- List of Contributors -- List of Figures -- List of Tables -- List of Abbreviations -- Chapter 1 - Selective Expansion of Limbal Epithelial Stem Cells in Culture Using Hypoxia -- 1.1 Introduction -- 1.2 Clinical Application of Bioengineered Corneal Epithelial Stem Cell Grafts -- 1.3 Culture Techniques for Bioengineered Stem Cell Sheets -- 1.4 Selective Expansion of LESCs Using Hypoxia -- 1.5 Future Perspectives -- References -- Chapter 2 - Mesenchymal Stem Cells and Pathotropism: Regenerative Potential and Safety Concerns -- 2.1 Introduction -- 2.2 Mesenchymal Stem Cells (MSC) -- 2.2.1 MSC Immunology -- 2.3 MSC in Tumor Support -- 2.3.1 MSC in Drug Delivery to Tumors -- 2.4 Conclusion -- References -- Chapter 3 - Prospective Technologies for Cardiac Repair -- 3.1 Medicine Changing Needs -- 3.2 Additive Technologies in Tissue Engineering -- References -- Chapter 4 - Does Inter-Individual Heterogeneity in the Normal Breast Corrupt Cancer Stem Cell and/or Cancer-Specific Signaling Characterization? -- 4.1 Introduction -- 4.2 Defining Normal Breast Hierarchy -- 4.3 Need for In Vitro Assays to Document Inter-Individual Heterogeneity in the Normal Breast -- 4.4 Future Directions -- Acknowledgements -- References -- Chapter 5 - The Role of Physical Microenvironmental Cues on Myogenesis: Implications for Tissue Engineering of Skeletal Muscle -- 5.1 Introduction -- 5.2 In Vitro Models of Adult Myogenesis -- 5.3 Effect of Soluble and Bound Biochemical Cues -- 5.4 Regulation of Cell Fate by Passive Physical Cues -- 5.4.1 Substrate Topography -- 5.4.2 Substrate Stiffness.
5.5 Active Stimulation -- 5.5.1 Electrical Stimulation -- 5.5.2 Mechanical Loading -- 5.6 Summary and Perspectives -- References -- Chapter 6 - Effect of Bioactive Growth Surfaces on Human Mesenchymal Stem Cells: A Pilot Biomarker Study to Assess Growth and Differentiation -- 6.1 Introduction -- 6.2 Materials and Methods -- 6.2.1 Materials -- 6.2.2 Cell Culture Reagents -- 6.2.3 Culture of Human MSCs -- 6.2.4 qPCR for Stem Cell Markers -- 6.3 Results -- 6.4 Discussion -- 6.5 Conclusions -- Acknowledgements -- References -- Chapter 7 - Embryonic Stem Cell Markers in Cancer: Cripto-1 Expression in Glioblastoma -- 7.1 Introduction -- 7.2 Glioma Stem Cells (GSC) -- 7.3 A New Cancer Stem Cell Marker in the Tumor Scaffold -- 7.4 Cr-1 Expression in GBMTissue and the Angiogenic Phenotype -- 7.5 CR-1 Expression Linked to Poorer Prognosis and Shorter Survival -- 7.6 Conclusion -- References -- Chapter 8 Artificial Corneas, and Reinforced Composite Implants for High Risk Donor Cornea Transplantation -- 8.1 Introduction -- 8.1.1 Cornea Transplantation -- 8.2 Artificial Corneas as Prostheses and Regeneration Templates -- 8.2.1 Artificial Corneas as Prostheses -- 8.2.2 Artificial Corneas as Regeneration Templates -- 8.3 Reinforced Collagen Corneal Implants -- 8.3.1 Interpenetrating Networks of Collagen-Phosphorylcholine as Implants -- 8.3.2 RHCIII-MPC Implants in Herpes Simplex Keratitis -- 8.4 Composite Corneal Implants with Peptide and Gene Therapy Capacity -- 8.4.1 LL-37 -- 8.4.2 Implants LL-37 Peptide Release -- 8.4.3 Composite Collagen-Cell-Based Implants -- 8.5 Conclusion -- Ackowledgements -- References -- Chapter 9 - Molecular Mechanisms of Smooth Muscle Cell Differentiation from Adipose-Derived Stem Cell -- 9.1 Introduction -- 9.2 SMC and ASC Characterization -- 9.3 Differentiation of SMC from ASC and Possible Molecular Mechanism.
9.4 Conclusion and Perspectives -- 9.5 Conflict of Interest -- References -- Index -- About the Editors -- Back Cover.
Record Nr. UNINA-9910538306603321
Gistrup, Denmark ; ; Delft, The Netherlands : , : River Publishers, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Tumor Microenvironment : The Role of Interleukins – Part B / / edited by Alexander Birbrair
Tumor Microenvironment : The Role of Interleukins – Part B / / edited by Alexander Birbrair
Edizione [1st ed. 2021.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021
Descrizione fisica 1 online resource (XII, 134 p. 23 illus., 11 illus. in color.)
Disciplina 616.994071
Collana Advances in Experimental Medicine and Biology
Soggetto topico Cancer
Tumors—Immunological aspects
Cytology
Internal medicine
Cancer Microenvironment
Tumour Immunology
Cancer Biology
Cell Biology
Internal Medicine
ISBN 3-030-55617-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Interleukin-6 function and targeting in prostate cancer -- IL-7 signaling in the tumor microenvironment -- IL-10 Signaling in the Tumor Microenvironment of Epithelial Ovarian Cancer -- Targeted delivery of IL-12 adjuvants immunotherapy by oncolytic viruses -- IL-22 signaling in the tumor microenvironment -- IL-23 and the Tumor Microenvironment -- Interleukin (IL)-24: Reconfiguring the tumor microenvironment for eliciting antitumor response -- Interleukin-31, a potent pruritus-inducing cytokine and its role in inflammatory disease and in the tumor microenvironment -- Index.
Record Nr. UNINA-9910484179703321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Tumor Microenvironment : Study Protocols / / edited by Constantinos Koumenis, Lisa M. Coussens, Amato Giaccia, Ester Hammond
Tumor Microenvironment : Study Protocols / / edited by Constantinos Koumenis, Lisa M. Coussens, Amato Giaccia, Ester Hammond
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Descrizione fisica 1 online resource (VIII, 297 p. 85 illus., 64 illus. in color.)
Disciplina 616.994071
Collana Advances in Experimental Medicine and Biology
Soggetto topico Cancer research
Molecular biology
Immunology
Cancer Research
Molecular Medicine
ISBN 3-319-26666-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1.Staining against phospho-H2AX (γ-H2AX) as a marker for DNA damage and genomic instability in cancer tissues and cells -- 2.Measuring DNA replication rates in hypoxic conditions -- 3.Isolation of Proteins on Nascent DNA in hypoxia and reoxygenation conditions -- 4.In vivo interrogation of the hypoxic transcriptome of solid tumors: optimizing hypoxic probe labelling with Laser-Capture Microdissection for isolation of high-quality RNA for deep sequencing analysis -- 5.Gas chromatography coupled to mass spectrometry (GC-MS) to study metabolism in cultured cells -- 6.Probing Cancer Cell Metabolism using NMR Spectroscopy -- 7.Measuring the Impact of Microenvironmental Conditions on Mitochondrial Dehydrogenases Activity in Cultured Cells -- 8.Measuring Autophagy in the Context of Cancer -- 9.Methods for studying autophagy within the tumor microenvironment -- 10.Using 3 Dimensional Culture (Spheroids) as an in vitro Model of Tumour Hypoxia -- 11.Isolation of Glioma Initiating Cells for Biological Study -- 12.Isolation of mouse and human tumor associated macrophages -- 13.Mouse models of brain metastasis for unravelling tumour progression -- 14.Quantification of lung metastases from in vivo mouse models -- 15.A multimodal data analysis approach for targeted drug discovery involving topological data analysis (TDA) -- 16.Efficient protocol for the identification of hypoxic cell radiosensitisers.
Record Nr. UNINA-9910253873803321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
The Unfolded Protein Response in Cancer / / edited by Robert Clarke
The Unfolded Protein Response in Cancer / / edited by Robert Clarke
Edizione [1st ed. 2019.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Humana, , 2019
Descrizione fisica 1 online resource (227 pages)
Disciplina 616.994071
616.99407
Collana Cancer Drug Discovery and Development
Soggetto topico Cancer research
Cancer Research
ISBN 3-030-05067-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction: The Unfolded Protein Response -- Endoplasmic Reticulum Stress Signaling During Development -- Regulation of the Unfolded Protein Response and its Roles in Tumorigenesis and Cancer Therapy -- ATF4, Hypoxia and Treatment Resistance in Cancer -- Role of Protein Translation in the Unfolded Protein Response -- Roles of Spliced and Unspliced XBP1 in Breast Cancer -- The Unfolded Protein Response in Triple-Negative Breast Cancer -- The Unfolded Protein Response as an Integrator of Response to Endocrine Therapy in Estrogen Receptor Positive Breast Cancer -- Outside the Endoplasmic Reticulum: Non-Canonical GRP78 Signaling -- Autophagy and the Unfolded Protein Response in Neurodegenerative Diseases -- Index.
Record Nr. UNINA-9910337508003321
Cham : , : Springer International Publishing : , : Imprint : Humana, , 2019
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Vesicle Trafficking in Cancer [[electronic resource] /] / edited by Yosef Yarden, Gabi Tarcic
Vesicle Trafficking in Cancer [[electronic resource] /] / edited by Yosef Yarden, Gabi Tarcic
Edizione [1st ed. 2013.]
Pubbl/distr/stampa New York, NY : , : Springer New York : , : Imprint : Springer, , 2013
Descrizione fisica 1 online resource (393 p.)
Disciplina 616.99
616.99/4
616.994071
Soggetto topico Cancer research
Cell biology
Biochemistry
Posttranslational modification
Proteins 
Cancer Research
Cell Biology
Biochemistry, general
Posttranslational Modification
Receptors
ISBN 1-4614-6528-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Clathrin Mediated Endocytosis -- Intimate And Facultative? Regulation Of Clathrin-Mediated Endocytosis By The Actin Cytoskeleton -- Oncogenic Signaling From The Plasma Membrane -- Endocytosis In The Spatial Control Of Polarized Cell Functions -- Aberrant Vesicular Trafficking Contributes To Altered Polarity And Metabolism In Cancer -- Endocytosis And The Regulation Of Cell Signaling, Cell Adhesion, And Epithelial To Mesenchymal Transition In Cancer -- Efficient Enhancement Of Signaling Capacity: Signaling Endosomes -- Nuclear Functions And Trafficking Of Receptor Tyrosine Kinases -- Efficient Enhancement Of Signaling Capacity – The Ubiquitin System.-  Molecular Mechanism Of Ubiquitin-Dependent Traffic -- Cbl As A Master Regulator Of Receptor Tyrosine Kinase Trafficking -- Regulation Of Endocytic Trafficking And Signaling By Deubiquitylating Enzymes -- RTKs As Models For Trafficking Regulation - C-Met/HGF-Receptor- C-Met Signalling In Cancer: Location Counts -- Regulation Of Epidermal Growth Factor Receptor Signaling By Endocytosis In Normal And Malignant Cells -- Stress-Driven Endocytosis Of Tyrosine-Phosphorylated EGFR Leads To Tumorigenesis: The Critical Role Of Oxidative Stress -- Internalisation, Endosomal Trafficking And Recycling Of Integrins During Cell Migration And Cancer Invasion -- Antibody-mediated receptor endocytosis: Harnessing the cellular machinery to combat cancer -- Index.
Record Nr. UNINA-9910739430703321
New York, NY : , : Springer New York : , : Imprint : Springer, , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui