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Small Molecules in Oncology [[electronic resource] /] / edited by Uwe M. Martens
| Small Molecules in Oncology [[electronic resource] /] / edited by Uwe M. Martens |
| Edizione | [2nd ed. 2014.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (418 p.) |
| Disciplina | 616.994071 |
| Collana | Recent Results in Cancer Research |
| Soggetto topico |
Oncology
Hematology Cancer research Oncology Cancer Research |
| ISBN | 3-642-54490-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Imatinib Mesylate -- Erlotinib -- Axitinib (AG-013736) -- Lapatinib -- Sorafenib -- Sunitinib -- Dasatinib -- Nilotinib -- Bosutinib -- Decitabine -- Azacytidine/Azacitidine -- Bortezomib -- Temsirolimus -- Danusertib -- Vismodegib -- Everolimus -- Vemurafenib -- Vandetanib -- Trametinib -- Dabrafenib -- Ponatinib -- Regorafenib -- Cabozantinib -- Revlimid -- Ibrutinib -- Qizartinib -- Ruxolitinib -- Carfilzomib -- Afitinib. |
| Record Nr. | UNINA-9910300336403321 |
| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Some industrial chemicals [[electronic resource]]
| Some industrial chemicals [[electronic resource]] |
| Pubbl/distr/stampa | Lyon, France, : IARC |
| Descrizione fisica | 1 online resource (573 p.) |
| Disciplina |
615.902
616.994071 |
| Collana | IARC monographs on the evaluation of carcinogenic risks to humans |
| Soggetto topico |
Carcinogens
Industrial toxicology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-77600-9
92-832-1584-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910453420303321 |
| Lyon, France, : IARC | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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STAT Inhibitors in Cancer / / edited by Alister C. Ward
| STAT Inhibitors in Cancer / / edited by Alister C. Ward |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Humana, , 2016 |
| Descrizione fisica | 1 online resource (VII, 195 p. 11 illus. in color.) |
| Disciplina | 616.994071 |
| Collana | Cancer Drug Discovery and Development |
| Soggetto topico |
Cancer research
Cancer Research |
| ISBN | 9783319429496 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | STATs in Health and Disease -- STAT Proteins in Cancer -- Translating STAT Inhibitors from the Lab to the Clinic -- Historical Development of STAT3 Inhibitors and Early Results in Clinical Trials -- STAT3 Inhibitors in Cancer: A Comprehensive Update -- Targeting Upstream Janus Kinases -- Inhibitors of Upstream Inducers of STAT Activation. |
| Record Nr. | UNINA-9910254539403321 |
| Cham : , : Springer International Publishing : , : Imprint : Humana, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Steam cell microenvironment and its role in regenerative medicine and cancer pathogenisis / / editors, Cristian Pablo Pennisi, Mayuri Sinha Prasad, Pranela Rameshwar
| The Steam cell microenvironment and its role in regenerative medicine and cancer pathogenisis / / editors, Cristian Pablo Pennisi, Mayuri Sinha Prasad, Pranela Rameshwar |
| Pubbl/distr/stampa | Alsbjergvej, Gistrup, Denmark ; ; Delft, The Netherlands : , : River Publishers, , 2017 |
| Descrizione fisica | 1 online resource (144 pages) : illustrations (some color), tables |
| Disciplina | 616.994071 |
| Collana | River Publishers Series in Research and Business Chronicles: Biotechnology and Medicine |
| Soggetto topico |
Carcinogenesis
Carcinogens Regenerative medicine |
| Soggetto genere / forma | Electronic books. |
| ISBN | 87-93519-00-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910466358103321 |
| Alsbjergvej, Gistrup, Denmark ; ; Delft, The Netherlands : , : River Publishers, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The stem cell microenvironment and its role in regenerative medicine and cancer pathogenisis / / editors, Cristian Pablo Pennisi, Mayuri Sinha Prasad, Pranela Rameshwar
| The stem cell microenvironment and its role in regenerative medicine and cancer pathogenisis / / editors, Cristian Pablo Pennisi, Mayuri Sinha Prasad, Pranela Rameshwar |
| Edizione | [First edition.] |
| Pubbl/distr/stampa | Gistrup, Denmark ; ; Delft, The Netherlands : , : River Publishers, , 2017 |
| Descrizione fisica | 1 online resource (144 pages) : illustrations (some color), tables |
| Disciplina | 616.994071 |
| Collana | River Publishers series in research and business chronicles: biotechnology and medicine |
| Soggetto topico |
Carcinogenesis
Carcinogens Regenerative medicine |
| ISBN |
1-00-333977-8
1-003-33977-8 1-000-79411-3 1-000-79525-X 87-93519-00-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover -- Half Title Page -- RIVER PUBLISHERS SERIES IN RESEARCH AND BUSINESS CHRONICLES: BIOTECHNOLOGY AND MEDICINE -- Full Title - The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis -- Copyright Page -- Contents -- Preface -- List of Contributors -- List of Figures -- List of Tables -- List of Abbreviations -- Chapter 1 - Selective Expansion of Limbal Epithelial Stem Cells in Culture Using Hypoxia -- 1.1 Introduction -- 1.2 Clinical Application of Bioengineered Corneal Epithelial Stem Cell Grafts -- 1.3 Culture Techniques for Bioengineered Stem Cell Sheets -- 1.4 Selective Expansion of LESCs Using Hypoxia -- 1.5 Future Perspectives -- References -- Chapter 2 - Mesenchymal Stem Cells and Pathotropism: Regenerative Potential and Safety Concerns -- 2.1 Introduction -- 2.2 Mesenchymal Stem Cells (MSC) -- 2.2.1 MSC Immunology -- 2.3 MSC in Tumor Support -- 2.3.1 MSC in Drug Delivery to Tumors -- 2.4 Conclusion -- References -- Chapter 3 - Prospective Technologies for Cardiac Repair -- 3.1 Medicine Changing Needs -- 3.2 Additive Technologies in Tissue Engineering -- References -- Chapter 4 - Does Inter-Individual Heterogeneity in the Normal Breast Corrupt Cancer Stem Cell and/or Cancer-Specific Signaling Characterization? -- 4.1 Introduction -- 4.2 Defining Normal Breast Hierarchy -- 4.3 Need for In Vitro Assays to Document Inter-Individual Heterogeneity in the Normal Breast -- 4.4 Future Directions -- Acknowledgements -- References -- Chapter 5 - The Role of Physical Microenvironmental Cues on Myogenesis: Implications for Tissue Engineering of Skeletal Muscle -- 5.1 Introduction -- 5.2 In Vitro Models of Adult Myogenesis -- 5.3 Effect of Soluble and Bound Biochemical Cues -- 5.4 Regulation of Cell Fate by Passive Physical Cues -- 5.4.1 Substrate Topography -- 5.4.2 Substrate Stiffness.
5.5 Active Stimulation -- 5.5.1 Electrical Stimulation -- 5.5.2 Mechanical Loading -- 5.6 Summary and Perspectives -- References -- Chapter 6 - Effect of Bioactive Growth Surfaces on Human Mesenchymal Stem Cells: A Pilot Biomarker Study to Assess Growth and Differentiation -- 6.1 Introduction -- 6.2 Materials and Methods -- 6.2.1 Materials -- 6.2.2 Cell Culture Reagents -- 6.2.3 Culture of Human MSCs -- 6.2.4 qPCR for Stem Cell Markers -- 6.3 Results -- 6.4 Discussion -- 6.5 Conclusions -- Acknowledgements -- References -- Chapter 7 - Embryonic Stem Cell Markers in Cancer: Cripto-1 Expression in Glioblastoma -- 7.1 Introduction -- 7.2 Glioma Stem Cells (GSC) -- 7.3 A New Cancer Stem Cell Marker in the Tumor Scaffold -- 7.4 Cr-1 Expression in GBMTissue and the Angiogenic Phenotype -- 7.5 CR-1 Expression Linked to Poorer Prognosis and Shorter Survival -- 7.6 Conclusion -- References -- Chapter 8 Artificial Corneas, and Reinforced Composite Implants for High Risk Donor Cornea Transplantation -- 8.1 Introduction -- 8.1.1 Cornea Transplantation -- 8.2 Artificial Corneas as Prostheses and Regeneration Templates -- 8.2.1 Artificial Corneas as Prostheses -- 8.2.2 Artificial Corneas as Regeneration Templates -- 8.3 Reinforced Collagen Corneal Implants -- 8.3.1 Interpenetrating Networks of Collagen-Phosphorylcholine as Implants -- 8.3.2 RHCIII-MPC Implants in Herpes Simplex Keratitis -- 8.4 Composite Corneal Implants with Peptide and Gene Therapy Capacity -- 8.4.1 LL-37 -- 8.4.2 Implants LL-37 Peptide Release -- 8.4.3 Composite Collagen-Cell-Based Implants -- 8.5 Conclusion -- Ackowledgements -- References -- Chapter 9 - Molecular Mechanisms of Smooth Muscle Cell Differentiation from Adipose-Derived Stem Cell -- 9.1 Introduction -- 9.2 SMC and ASC Characterization -- 9.3 Differentiation of SMC from ASC and Possible Molecular Mechanism. 9.4 Conclusion and Perspectives -- 9.5 Conflict of Interest -- References -- Index -- About the Editors -- Back Cover. |
| Record Nr. | UNINA-9910538306603321 |
| Gistrup, Denmark ; ; Delft, The Netherlands : , : River Publishers, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Microenvironment : The Role of Interleukins – Part B / / edited by Alexander Birbrair
| Tumor Microenvironment : The Role of Interleukins – Part B / / edited by Alexander Birbrair |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 |
| Descrizione fisica | 1 online resource (XII, 134 p. 23 illus., 11 illus. in color.) |
| Disciplina | 616.994071 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cancer
Tumors—Immunological aspects Cytology Internal medicine Cancer Microenvironment Tumour Immunology Cancer Biology Cell Biology Internal Medicine |
| ISBN | 3-030-55617-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Interleukin-6 function and targeting in prostate cancer -- IL-7 signaling in the tumor microenvironment -- IL-10 Signaling in the Tumor Microenvironment of Epithelial Ovarian Cancer -- Targeted delivery of IL-12 adjuvants immunotherapy by oncolytic viruses -- IL-22 signaling in the tumor microenvironment -- IL-23 and the Tumor Microenvironment -- Interleukin (IL)-24: Reconfiguring the tumor microenvironment for eliciting antitumor response -- Interleukin-31, a potent pruritus-inducing cytokine and its role in inflammatory disease and in the tumor microenvironment -- Index. |
| Record Nr. | UNINA-9910484179703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Microenvironment : Study Protocols / / edited by Constantinos Koumenis, Lisa M. Coussens, Amato Giaccia, Ester Hammond
| Tumor Microenvironment : Study Protocols / / edited by Constantinos Koumenis, Lisa M. Coussens, Amato Giaccia, Ester Hammond |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (VIII, 297 p. 85 illus., 64 illus. in color.) |
| Disciplina | 616.994071 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cancer research
Molecular biology Immunology Cancer Research Molecular Medicine |
| ISBN | 3-319-26666-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1.Staining against phospho-H2AX (γ-H2AX) as a marker for DNA damage and genomic instability in cancer tissues and cells -- 2.Measuring DNA replication rates in hypoxic conditions -- 3.Isolation of Proteins on Nascent DNA in hypoxia and reoxygenation conditions -- 4.In vivo interrogation of the hypoxic transcriptome of solid tumors: optimizing hypoxic probe labelling with Laser-Capture Microdissection for isolation of high-quality RNA for deep sequencing analysis -- 5.Gas chromatography coupled to mass spectrometry (GC-MS) to study metabolism in cultured cells -- 6.Probing Cancer Cell Metabolism using NMR Spectroscopy -- 7.Measuring the Impact of Microenvironmental Conditions on Mitochondrial Dehydrogenases Activity in Cultured Cells -- 8.Measuring Autophagy in the Context of Cancer -- 9.Methods for studying autophagy within the tumor microenvironment -- 10.Using 3 Dimensional Culture (Spheroids) as an in vitro Model of Tumour Hypoxia -- 11.Isolation of Glioma Initiating Cells for Biological Study -- 12.Isolation of mouse and human tumor associated macrophages -- 13.Mouse models of brain metastasis for unravelling tumour progression -- 14.Quantification of lung metastases from in vivo mouse models -- 15.A multimodal data analysis approach for targeted drug discovery involving topological data analysis (TDA) -- 16.Efficient protocol for the identification of hypoxic cell radiosensitisers. |
| Record Nr. | UNINA-9910253873803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Unfolded Protein Response in Cancer / / edited by Robert Clarke
| The Unfolded Protein Response in Cancer / / edited by Robert Clarke |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Humana, , 2019 |
| Descrizione fisica | 1 online resource (227 pages) |
| Disciplina |
616.994071
616.99407 |
| Collana | Cancer Drug Discovery and Development |
| Soggetto topico |
Cancer research
Cancer Research |
| ISBN | 3-030-05067-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction: The Unfolded Protein Response -- Endoplasmic Reticulum Stress Signaling During Development -- Regulation of the Unfolded Protein Response and its Roles in Tumorigenesis and Cancer Therapy -- ATF4, Hypoxia and Treatment Resistance in Cancer -- Role of Protein Translation in the Unfolded Protein Response -- Roles of Spliced and Unspliced XBP1 in Breast Cancer -- The Unfolded Protein Response in Triple-Negative Breast Cancer -- The Unfolded Protein Response as an Integrator of Response to Endocrine Therapy in Estrogen Receptor Positive Breast Cancer -- Outside the Endoplasmic Reticulum: Non-Canonical GRP78 Signaling -- Autophagy and the Unfolded Protein Response in Neurodegenerative Diseases -- Index. |
| Record Nr. | UNINA-9910337508003321 |
| Cham : , : Springer International Publishing : , : Imprint : Humana, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Vesicle Trafficking in Cancer [[electronic resource] /] / edited by Yosef Yarden, Gabi Tarcic
| Vesicle Trafficking in Cancer [[electronic resource] /] / edited by Yosef Yarden, Gabi Tarcic |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (393 p.) |
| Disciplina |
616.99
616.99/4 616.994071 |
| Soggetto topico |
Cancer research
Cell biology Biochemistry Posttranslational modification Proteins Cancer Research Cell Biology Biochemistry, general Posttranslational Modification Receptors |
| ISBN | 1-4614-6528-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Clathrin Mediated Endocytosis -- Intimate And Facultative? Regulation Of Clathrin-Mediated Endocytosis By The Actin Cytoskeleton -- Oncogenic Signaling From The Plasma Membrane -- Endocytosis In The Spatial Control Of Polarized Cell Functions -- Aberrant Vesicular Trafficking Contributes To Altered Polarity And Metabolism In Cancer -- Endocytosis And The Regulation Of Cell Signaling, Cell Adhesion, And Epithelial To Mesenchymal Transition In Cancer -- Efficient Enhancement Of Signaling Capacity: Signaling Endosomes -- Nuclear Functions And Trafficking Of Receptor Tyrosine Kinases -- Efficient Enhancement Of Signaling Capacity – The Ubiquitin System.- Molecular Mechanism Of Ubiquitin-Dependent Traffic -- Cbl As A Master Regulator Of Receptor Tyrosine Kinase Trafficking -- Regulation Of Endocytic Trafficking And Signaling By Deubiquitylating Enzymes -- RTKs As Models For Trafficking Regulation - C-Met/HGF-Receptor- C-Met Signalling In Cancer: Location Counts -- Regulation Of Epidermal Growth Factor Receptor Signaling By Endocytosis In Normal And Malignant Cells -- Stress-Driven Endocytosis Of Tyrosine-Phosphorylated EGFR Leads To Tumorigenesis: The Critical Role Of Oxidative Stress -- Internalisation, Endosomal Trafficking And Recycling Of Integrins During Cell Migration And Cancer Invasion -- Antibody-mediated receptor endocytosis: Harnessing the cellular machinery to combat cancer -- Index. |
| Record Nr. | UNINA-9910739430703321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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