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Schiff's diseases of the liver [[electronic resource] /] / edited by Eugene R. Schiff, Willis C. Maddrey, Michael F. Sorrell
Schiff's diseases of the liver [[electronic resource] /] / edited by Eugene R. Schiff, Willis C. Maddrey, Michael F. Sorrell
Edizione [11th ed.]
Pubbl/distr/stampa Chichester, West Sussex, U.K. ; ; Hoboken, N.J., : John Wiley & Sons, 2012
Descrizione fisica 1 online resource (1267 p.)
Disciplina 616.3/62
Altri autori (Persone) SchiffEugene R
MaddreyWillis C
SorrellMichael F
SchiffLeon <1901-1994.>
Soggetto topico Liver - Diseases
ISBN 1-283-33304-X
9786613333049
1-119-95050-3
1-119-95047-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Schiff's Diseases of the Liver; Contents; List of Contributors; Foreword; Preface; Part I Overview: Clinical Fundamentals of Hepatology; 1 History Taking and Physical Examination for the Patient with Liver Disease; 2 Laboratory Tests; 3 Liver Biopsy and Laparoscopy; 4 Noninvasive and Invasive Imaging of the Liver and Biliary Tract; Part II General Considerations; 5 Physioanatomic Considerations; 6 Bilirubin Metabolism and Jaundice; 7 Hepatic Histopathology; 8 Mechanisms of Liver Injury; 9 Hepatic Manifestations of Systemic Disorders
10 Hepatobiliary Complications of Hematopoietic Cell Transplantation 11 The Liver in Pregnancy; Part III Consequences of Liver Disease; 12 Hepatic Fibrosis; 13 Preoperative Evaluation of the Patient with Liver Disease; 14 Portal Hypertension: Nonsurgical and Surgical Management; 15 Renal Complications of Liver Disease and the Hepatorenal Syndrome; 16 Pulmonary Manifestations of Liver Disease; 17 Ascites and Spontaneous Bacterial Peritonitis; 18 Hepatic Encephalopathy; 19 Acute Liver Failure; Part IV Cholestatic Disorders; 20 Primary Sclerosing Cholangitis; 21 Primary Biliary Cirrhosis
22 Autoimmune Hepatitis Part V Viral Hepatitis; Overview; 23 Hepatitis A and E; 24 Hepatitis B and D; 25 Hepatitis C; Part VI Alcohol and Drug-induced Liver Disease; Overview; 26 Alcoholic Liver Disease; 27 Drug-induced Liver Disease; 28 Mechanisms of Drug-induced Liver Injury; Part VII Genetic and Metabolic Disease; 29 Wilson Disease; 30 Hemochromatosis and Iron Storage Disorders; 31 Alpha-1 Antitrypsin Deficiency; 32 Nonalcoholic Fatty Liver Disease; Part VIII Vascular Diseases of the Liver; 33 Vascular Diseases of the Liver; 34 The Liver in Circulatory Failure
Part IX Benign and Malignant Tumors Cystic Disorders; 35 Benign Tumors, Nodules, and Cystic Diseases of the Liver; 36 Hepatocellular Carcinoma; 37 Surgical Options in Liver Cancers; Part X Infectious and Granulomatous Disease; 38 Amoebic and Pyogenic Liver Abscesses; 39 Parasitic Diseases; 40 Granulomas of the Liver; 41 Hepatobiliary Manifestations of Human Immunodeficiency Virus; Part XI Elements of Liver Transplantation; Overview; 42 Selection and Timing of Liver Transplantation; 43 Immunosuppression: The Global Picture; 44 The First Six Months Following Liver Transplantation
45 Long-term Management of the Liver Transplant Patient 46 The Liver Transplant Procedure; 47 Recurrent Disease Following Liver Transplantation; 48 The Role of Retransplantation; 49 Controversies in Liver Transplantation; Appendix Multiple Choice Answers; Index
Record Nr. UNINA-9910819394103321
Chichester, West Sussex, U.K. ; ; Hoboken, N.J., : John Wiley & Sons, 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Signaling pathways in liver diseases / / [edited by] Jean-François Dufour, Pierre-Alain Clavien
Signaling pathways in liver diseases / / [edited by] Jean-François Dufour, Pierre-Alain Clavien
Edizione [Third edition.]
Pubbl/distr/stampa Chichester, West Sussex, UK ; ; Hoboken, NJ, USA : , : John Wiley & Sons, Ltd, , 2016
Descrizione fisica 1 online resource (520 p.)
Disciplina 616.3/62
Soggetto topico Liver Diseases - Pathophysiology
Liver - cytology
Cellular signal transduction
ISBN 1-118-66338-1
1-118-66335-7
1-118-66336-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title Page; Copyright Page; Contents; List of Contributors; Chapter 1 Hepatocytes; Introduction; Liver and hepatocyte development; Phenotype and regeneration of the mature hepatocyte; Metabolic functions of the liver; Resorption, storage, and synthesis; Detoxification and excretion; Detoxification of specific substances; Excretion; Multiple choice questions; References; Chapter 2 Signaling pathways in biliary epithelial cells; Introduction; Membrane receptors; Cyclic adenosine 3', 5'-monophosphate (cAMP); Cytosolic Ca2+; Protein kinase C; Mitogen-activated protein kinase signaling
Phosphotidylinositol 3-kinase signaling Notch signaling; Hedgehog signaling; Vascular endothelial growth factor; Pathological conditions; Conclusion; Acknowledgments; Multiple choice questions; References; Chapter 3 Stellate cells; Polypeptide growth factor receptors; Transforming growth factor-β receptor superfamily; Seven transmembrane domain receptors; Chemokines; Tumor necrosis factor receptor superfamily; Nuclear receptor family; Other cytokine receptors; Adipokine receptors; Extracellular matrix signaling and hepatic stellate cells; Toll-like receptors; Cannabinoid receptors
Hedgehog pathway Wnt pathway; Autophagy; Senescence of activated stellate cells; miRNAs and hepatic stellate cells; Conclusion; Multiple choice questions; References; Chapter 4 Kupffer cells; Introduction; Markers, origin, and heterogeneity of Kupffer cells; M1 versus M2 polarization in Kupffer cells; Lipopolysaccharide signaling and endotoxin tolerance; Experimental approaches to deplete Kupffer cells in vivo; Role of Kupffer cells in liver disease; Nonalcoholic fatty liver disease/nonalcoholic steatohepatitis; Alcoholic liver disease; Liver regeneration; Liver fibrosis and cirrhosis
Ischemia-reperfusion liver injury Primary and metastatic liver tumors; Infectious diseases; Clinical applications and future perspectives; Acknowledgment; Multiple choice questions; References; Chapter 5 Hepatic sinusoidal endothelial cells; Development and structure; Cellular functions; Filtration via fenestrae; Diapedesis; Nitric oxide signaling; Endocytosis; Bacterial processing; Liver regeneration; Pathobiology; Fibrosis and cirrhosis; Alcoholic liver disease; Nonalcoholic fatty liver disease; Hepatic malignancies; Drug toxicity; Ischemia-reperfusion injury; Aging process; Conclusion
Multiple choice questions References; Chapter 6 Extracellular matrix; Introduction; Components of the extracellular matrix in liver (Figure 6.1); The collagen scaffold; Proteoglycans; Laminin; Fibronectin; Matricellular proteins; Changes in the extracellular matrix from normal to fibrotic liver; Pathways of cell-matrix interaction; Integrin family; ADAM molecules; Discoidin domain receptors; Growth factors in ECM (Figure 6.4); The extracellular matrix and the stem cell niche; Metalloproteinases and their inhibitors; Conclusion; Multiple choice questions; References
Chapter 7 Platelets: a new cell type in liver physiology
Record Nr. UNINA-9910131634803321
Chichester, West Sussex, UK ; ; Hoboken, NJ, USA : , : John Wiley & Sons, Ltd, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Signaling pathways in liver diseases / / [edited by] Jean-François Dufour, Pierre-Alain Clavien
Signaling pathways in liver diseases / / [edited by] Jean-François Dufour, Pierre-Alain Clavien
Edizione [Third edition.]
Pubbl/distr/stampa Chichester, West Sussex, UK ; ; Hoboken, NJ, USA : , : John Wiley & Sons, Ltd, , 2016
Descrizione fisica 1 online resource (520 p.)
Disciplina 616.3/62
Soggetto topico Liver Diseases - Pathophysiology
Liver - cytology
Cellular signal transduction
ISBN 1-118-66338-1
1-118-66335-7
1-118-66336-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title Page; Copyright Page; Contents; List of Contributors; Chapter 1 Hepatocytes; Introduction; Liver and hepatocyte development; Phenotype and regeneration of the mature hepatocyte; Metabolic functions of the liver; Resorption, storage, and synthesis; Detoxification and excretion; Detoxification of specific substances; Excretion; Multiple choice questions; References; Chapter 2 Signaling pathways in biliary epithelial cells; Introduction; Membrane receptors; Cyclic adenosine 3', 5'-monophosphate (cAMP); Cytosolic Ca2+; Protein kinase C; Mitogen-activated protein kinase signaling
Phosphotidylinositol 3-kinase signaling Notch signaling; Hedgehog signaling; Vascular endothelial growth factor; Pathological conditions; Conclusion; Acknowledgments; Multiple choice questions; References; Chapter 3 Stellate cells; Polypeptide growth factor receptors; Transforming growth factor-β receptor superfamily; Seven transmembrane domain receptors; Chemokines; Tumor necrosis factor receptor superfamily; Nuclear receptor family; Other cytokine receptors; Adipokine receptors; Extracellular matrix signaling and hepatic stellate cells; Toll-like receptors; Cannabinoid receptors
Hedgehog pathway Wnt pathway; Autophagy; Senescence of activated stellate cells; miRNAs and hepatic stellate cells; Conclusion; Multiple choice questions; References; Chapter 4 Kupffer cells; Introduction; Markers, origin, and heterogeneity of Kupffer cells; M1 versus M2 polarization in Kupffer cells; Lipopolysaccharide signaling and endotoxin tolerance; Experimental approaches to deplete Kupffer cells in vivo; Role of Kupffer cells in liver disease; Nonalcoholic fatty liver disease/nonalcoholic steatohepatitis; Alcoholic liver disease; Liver regeneration; Liver fibrosis and cirrhosis
Ischemia-reperfusion liver injury Primary and metastatic liver tumors; Infectious diseases; Clinical applications and future perspectives; Acknowledgment; Multiple choice questions; References; Chapter 5 Hepatic sinusoidal endothelial cells; Development and structure; Cellular functions; Filtration via fenestrae; Diapedesis; Nitric oxide signaling; Endocytosis; Bacterial processing; Liver regeneration; Pathobiology; Fibrosis and cirrhosis; Alcoholic liver disease; Nonalcoholic fatty liver disease; Hepatic malignancies; Drug toxicity; Ischemia-reperfusion injury; Aging process; Conclusion
Multiple choice questions References; Chapter 6 Extracellular matrix; Introduction; Components of the extracellular matrix in liver (Figure 6.1); The collagen scaffold; Proteoglycans; Laminin; Fibronectin; Matricellular proteins; Changes in the extracellular matrix from normal to fibrotic liver; Pathways of cell-matrix interaction; Integrin family; ADAM molecules; Discoidin domain receptors; Growth factors in ECM (Figure 6.4); The extracellular matrix and the stem cell niche; Metalloproteinases and their inhibitors; Conclusion; Multiple choice questions; References
Chapter 7 Platelets: a new cell type in liver physiology
Record Nr. UNINA-9910827367903321
Chichester, West Sussex, UK ; ; Hoboken, NJ, USA : , : John Wiley & Sons, Ltd, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Textbook of hepatology [[electronic resource] ] : from basic science to clinical practice
Textbook of hepatology [[electronic resource] ] : from basic science to clinical practice
Edizione [3rd ed.]
Pubbl/distr/stampa Malden, MA, : Blackwell, c2007
Descrizione fisica 1 online resource (2358 p.)
Disciplina 616.3/62
616.362
Altri autori (Persone) RodésJoan
Soggetto topico Liver - Diseases
Liver - Tumors
Soggetto genere / forma Electronic books.
ISBN 1-281-30841-2
9786611308414
0-470-76178-4
0-470-69186-7
1-4051-8151-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto TEXTBOOK OF Hepatology : From Basic Science to Clinical Practice; Contents; Contributors; Foreword; Preface to the third edition; Preface to the first edition; Volume One; Section 1 Architecture of the liver; 1.1 Macroscopic anatomy of the liver; 1.2 Liver and biliary tract histology; 1.3 Ultrastructure of the hepatocyte; 1.4 Liver sinusoidal endothelial cells; 1.5 Kupffer cells; 1.6 The hepatic stellate cell; 1.7 Biliary epithelial cells; 1.8 Hepatic stem cells; 1.9 Embryology of the liver and intrahepatic biliary tract; Section 2 Functions of the liver; 2.1 Hepatic circulation
2.1.1 Regulation of hepatic blood flow2.1.2 Hepatic microcirculation; 2.1.3 Hepatic lymph and lymphatics; 2.2 Functions of the liver; 2.2.1 Functional organization of the liver; 2.2.2 Cell biology of the hepatocyte; 2.2.3 Molecular biology of the liver cell; 2.2.4 Hepatic transport processes; 2.2.5 Modulation of liver function by hepatic nerves; 2.2.6 In vitro techniques: isolated organ perfusion, slices, cells and subcellular elements; 2.3 Metabolism; 2.3.1 Carbohydrates and the liver; 2.3.2 Lipoprotein metabolism; 2.3.3 Protein and amino acid metabolism
2.3.4 Mitochondria and energy formation2.3.5 Bilirubin metabolism; 2.3.6 Metabolism of bile acids; 2.3.7 Ammonia, urea production and pH regulation; 2.3.8 Protein synthesis and degradation in the liver; 2.3.9 Glutathione; 2.3.10 Haem biosynthesis and excretion of porphyrins; 2.3.11 Vitamins and the liver (A and D); 2.3.12 Normal iron metabolism; 2.3.13 Normal copper metabolism and lowering copper to subnormal levels for therapeutic purposes; 2.3.14 Trace elements and the liver; 2.3.15 Hepatic metabolism of drugs; 2.4 Synthetic function; 2.4.1 Albumin and other carrier proteins
2.4.2 The liver and coagulation2.4.3 Function and metabolism of collagen and other extracellular matrix proteins; 2.5 Regulation of the liver cell mass; 2.5.1 Control of liver cell proliferation; 2.5.2 Regeneration of chronically injured liver; 2.6 Excretion; 2.6.1 Physiology of bile formation; 2.6.2 Motility of the biliary tree; 2.7 Immunology of the liver; 2.7.1 Cytokines in liver physiology and pathology; 2.7.2 Intrahepatic lymphocytes; 2.7.3 Antibody production and transport in the liver; Section 3 Basic concepts in pathobiology; 3.1 Hepatocyte apoptosis and necrosis
3.2 Ischaemia...reperfusion injury to the liver3.3 Genetics and liver diseases; 3.3.1 Genetic polymorphisms in liver disease; 3.3.2 Immunogenetics of liver disease; 3.3.3 Genetic determinants of complex liver diseases: mouse models and quantitative trait locus analysis; 3.4 Cellular cholestasis; 3.5 Oncogenes and tumour suppressor genes; 3.6 Genomics, gene arrays and proteomics in the study of liver disease; Section 4 Pathology; 4.1 Histological features; 4.2 Classifications, scoring systems and morphometry in liver pathology; Section 5 Investigation of hepatobiliary disease
5.1 Signs and symptoms of liver disease
Record Nr. UNINA-9910143301903321
Malden, MA, : Blackwell, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Textbook of hepatology [[electronic resource] ] : from basic science to clinical practice
Textbook of hepatology [[electronic resource] ] : from basic science to clinical practice
Edizione [3rd ed.]
Pubbl/distr/stampa Malden, MA, : Blackwell, c2007
Descrizione fisica 1 online resource (2358 p.)
Disciplina 616.3/62
616.362
Altri autori (Persone) RodésJoan
Soggetto topico Liver - Diseases
Liver - Tumors
ISBN 1-281-30841-2
9786611308414
0-470-76178-4
0-470-69186-7
1-4051-8151-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto TEXTBOOK OF Hepatology : From Basic Science to Clinical Practice; Contents; Contributors; Foreword; Preface to the third edition; Preface to the first edition; Volume One; Section 1 Architecture of the liver; 1.1 Macroscopic anatomy of the liver; 1.2 Liver and biliary tract histology; 1.3 Ultrastructure of the hepatocyte; 1.4 Liver sinusoidal endothelial cells; 1.5 Kupffer cells; 1.6 The hepatic stellate cell; 1.7 Biliary epithelial cells; 1.8 Hepatic stem cells; 1.9 Embryology of the liver and intrahepatic biliary tract; Section 2 Functions of the liver; 2.1 Hepatic circulation
2.1.1 Regulation of hepatic blood flow2.1.2 Hepatic microcirculation; 2.1.3 Hepatic lymph and lymphatics; 2.2 Functions of the liver; 2.2.1 Functional organization of the liver; 2.2.2 Cell biology of the hepatocyte; 2.2.3 Molecular biology of the liver cell; 2.2.4 Hepatic transport processes; 2.2.5 Modulation of liver function by hepatic nerves; 2.2.6 In vitro techniques: isolated organ perfusion, slices, cells and subcellular elements; 2.3 Metabolism; 2.3.1 Carbohydrates and the liver; 2.3.2 Lipoprotein metabolism; 2.3.3 Protein and amino acid metabolism
2.3.4 Mitochondria and energy formation2.3.5 Bilirubin metabolism; 2.3.6 Metabolism of bile acids; 2.3.7 Ammonia, urea production and pH regulation; 2.3.8 Protein synthesis and degradation in the liver; 2.3.9 Glutathione; 2.3.10 Haem biosynthesis and excretion of porphyrins; 2.3.11 Vitamins and the liver (A and D); 2.3.12 Normal iron metabolism; 2.3.13 Normal copper metabolism and lowering copper to subnormal levels for therapeutic purposes; 2.3.14 Trace elements and the liver; 2.3.15 Hepatic metabolism of drugs; 2.4 Synthetic function; 2.4.1 Albumin and other carrier proteins
2.4.2 The liver and coagulation2.4.3 Function and metabolism of collagen and other extracellular matrix proteins; 2.5 Regulation of the liver cell mass; 2.5.1 Control of liver cell proliferation; 2.5.2 Regeneration of chronically injured liver; 2.6 Excretion; 2.6.1 Physiology of bile formation; 2.6.2 Motility of the biliary tree; 2.7 Immunology of the liver; 2.7.1 Cytokines in liver physiology and pathology; 2.7.2 Intrahepatic lymphocytes; 2.7.3 Antibody production and transport in the liver; Section 3 Basic concepts in pathobiology; 3.1 Hepatocyte apoptosis and necrosis
3.2 Ischaemia...reperfusion injury to the liver3.3 Genetics and liver diseases; 3.3.1 Genetic polymorphisms in liver disease; 3.3.2 Immunogenetics of liver disease; 3.3.3 Genetic determinants of complex liver diseases: mouse models and quantitative trait locus analysis; 3.4 Cellular cholestasis; 3.5 Oncogenes and tumour suppressor genes; 3.6 Genomics, gene arrays and proteomics in the study of liver disease; Section 4 Pathology; 4.1 Histological features; 4.2 Classifications, scoring systems and morphometry in liver pathology; Section 5 Investigation of hepatobiliary disease
5.1 Signs and symptoms of liver disease
Record Nr. UNISA-996205345103316
Malden, MA, : Blackwell, c2007
Materiale a stampa
Lo trovi qui: Univ. di Salerno
Opac: Controlla la disponibilità qui
Textbook of hepatology [[electronic resource] ] : from basic science to clinical practice
Textbook of hepatology [[electronic resource] ] : from basic science to clinical practice
Edizione [3rd ed.]
Pubbl/distr/stampa Malden, MA, : Blackwell, c2007
Descrizione fisica 1 online resource (2358 p.)
Disciplina 616.3/62
616.362
Altri autori (Persone) RodésJoan
Soggetto topico Liver - Diseases
Liver - Tumors
ISBN 1-281-30841-2
9786611308414
0-470-76178-4
0-470-69186-7
1-4051-8151-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto TEXTBOOK OF Hepatology : From Basic Science to Clinical Practice; Contents; Contributors; Foreword; Preface to the third edition; Preface to the first edition; Volume One; Section 1 Architecture of the liver; 1.1 Macroscopic anatomy of the liver; 1.2 Liver and biliary tract histology; 1.3 Ultrastructure of the hepatocyte; 1.4 Liver sinusoidal endothelial cells; 1.5 Kupffer cells; 1.6 The hepatic stellate cell; 1.7 Biliary epithelial cells; 1.8 Hepatic stem cells; 1.9 Embryology of the liver and intrahepatic biliary tract; Section 2 Functions of the liver; 2.1 Hepatic circulation
2.1.1 Regulation of hepatic blood flow2.1.2 Hepatic microcirculation; 2.1.3 Hepatic lymph and lymphatics; 2.2 Functions of the liver; 2.2.1 Functional organization of the liver; 2.2.2 Cell biology of the hepatocyte; 2.2.3 Molecular biology of the liver cell; 2.2.4 Hepatic transport processes; 2.2.5 Modulation of liver function by hepatic nerves; 2.2.6 In vitro techniques: isolated organ perfusion, slices, cells and subcellular elements; 2.3 Metabolism; 2.3.1 Carbohydrates and the liver; 2.3.2 Lipoprotein metabolism; 2.3.3 Protein and amino acid metabolism
2.3.4 Mitochondria and energy formation2.3.5 Bilirubin metabolism; 2.3.6 Metabolism of bile acids; 2.3.7 Ammonia, urea production and pH regulation; 2.3.8 Protein synthesis and degradation in the liver; 2.3.9 Glutathione; 2.3.10 Haem biosynthesis and excretion of porphyrins; 2.3.11 Vitamins and the liver (A and D); 2.3.12 Normal iron metabolism; 2.3.13 Normal copper metabolism and lowering copper to subnormal levels for therapeutic purposes; 2.3.14 Trace elements and the liver; 2.3.15 Hepatic metabolism of drugs; 2.4 Synthetic function; 2.4.1 Albumin and other carrier proteins
2.4.2 The liver and coagulation2.4.3 Function and metabolism of collagen and other extracellular matrix proteins; 2.5 Regulation of the liver cell mass; 2.5.1 Control of liver cell proliferation; 2.5.2 Regeneration of chronically injured liver; 2.6 Excretion; 2.6.1 Physiology of bile formation; 2.6.2 Motility of the biliary tree; 2.7 Immunology of the liver; 2.7.1 Cytokines in liver physiology and pathology; 2.7.2 Intrahepatic lymphocytes; 2.7.3 Antibody production and transport in the liver; Section 3 Basic concepts in pathobiology; 3.1 Hepatocyte apoptosis and necrosis
3.2 Ischaemia...reperfusion injury to the liver3.3 Genetics and liver diseases; 3.3.1 Genetic polymorphisms in liver disease; 3.3.2 Immunogenetics of liver disease; 3.3.3 Genetic determinants of complex liver diseases: mouse models and quantitative trait locus analysis; 3.4 Cellular cholestasis; 3.5 Oncogenes and tumour suppressor genes; 3.6 Genomics, gene arrays and proteomics in the study of liver disease; Section 4 Pathology; 4.1 Histological features; 4.2 Classifications, scoring systems and morphometry in liver pathology; Section 5 Investigation of hepatobiliary disease
5.1 Signs and symptoms of liver disease
Record Nr. UNINA-9910830750603321
Malden, MA, : Blackwell, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Textbook of hepatology [[electronic resource] ] : from basic science to clinical practice
Textbook of hepatology [[electronic resource] ] : from basic science to clinical practice
Edizione [3rd ed.]
Pubbl/distr/stampa Malden, MA, : Blackwell, c2007
Descrizione fisica 1 online resource (2358 p.)
Disciplina 616.3/62
616.362
Altri autori (Persone) RodésJoan
Soggetto topico Liver - Diseases
Liver - Tumors
ISBN 1-281-30841-2
9786611308414
0-470-76178-4
0-470-69186-7
1-4051-8151-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto TEXTBOOK OF Hepatology : From Basic Science to Clinical Practice; Contents; Contributors; Foreword; Preface to the third edition; Preface to the first edition; Volume One; Section 1 Architecture of the liver; 1.1 Macroscopic anatomy of the liver; 1.2 Liver and biliary tract histology; 1.3 Ultrastructure of the hepatocyte; 1.4 Liver sinusoidal endothelial cells; 1.5 Kupffer cells; 1.6 The hepatic stellate cell; 1.7 Biliary epithelial cells; 1.8 Hepatic stem cells; 1.9 Embryology of the liver and intrahepatic biliary tract; Section 2 Functions of the liver; 2.1 Hepatic circulation
2.1.1 Regulation of hepatic blood flow2.1.2 Hepatic microcirculation; 2.1.3 Hepatic lymph and lymphatics; 2.2 Functions of the liver; 2.2.1 Functional organization of the liver; 2.2.2 Cell biology of the hepatocyte; 2.2.3 Molecular biology of the liver cell; 2.2.4 Hepatic transport processes; 2.2.5 Modulation of liver function by hepatic nerves; 2.2.6 In vitro techniques: isolated organ perfusion, slices, cells and subcellular elements; 2.3 Metabolism; 2.3.1 Carbohydrates and the liver; 2.3.2 Lipoprotein metabolism; 2.3.3 Protein and amino acid metabolism
2.3.4 Mitochondria and energy formation2.3.5 Bilirubin metabolism; 2.3.6 Metabolism of bile acids; 2.3.7 Ammonia, urea production and pH regulation; 2.3.8 Protein synthesis and degradation in the liver; 2.3.9 Glutathione; 2.3.10 Haem biosynthesis and excretion of porphyrins; 2.3.11 Vitamins and the liver (A and D); 2.3.12 Normal iron metabolism; 2.3.13 Normal copper metabolism and lowering copper to subnormal levels for therapeutic purposes; 2.3.14 Trace elements and the liver; 2.3.15 Hepatic metabolism of drugs; 2.4 Synthetic function; 2.4.1 Albumin and other carrier proteins
2.4.2 The liver and coagulation2.4.3 Function and metabolism of collagen and other extracellular matrix proteins; 2.5 Regulation of the liver cell mass; 2.5.1 Control of liver cell proliferation; 2.5.2 Regeneration of chronically injured liver; 2.6 Excretion; 2.6.1 Physiology of bile formation; 2.6.2 Motility of the biliary tree; 2.7 Immunology of the liver; 2.7.1 Cytokines in liver physiology and pathology; 2.7.2 Intrahepatic lymphocytes; 2.7.3 Antibody production and transport in the liver; Section 3 Basic concepts in pathobiology; 3.1 Hepatocyte apoptosis and necrosis
3.2 Ischaemia...reperfusion injury to the liver3.3 Genetics and liver diseases; 3.3.1 Genetic polymorphisms in liver disease; 3.3.2 Immunogenetics of liver disease; 3.3.3 Genetic determinants of complex liver diseases: mouse models and quantitative trait locus analysis; 3.4 Cellular cholestasis; 3.5 Oncogenes and tumour suppressor genes; 3.6 Genomics, gene arrays and proteomics in the study of liver disease; Section 4 Pathology; 4.1 Histological features; 4.2 Classifications, scoring systems and morphometry in liver pathology; Section 5 Investigation of hepatobiliary disease
5.1 Signs and symptoms of liver disease
Record Nr. UNINA-9910841292703321
Malden, MA, : Blackwell, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Zakim and Boyer's hepatology : a textbook of liver disease / / [edited by] Arun J. Sanyal, MBBS, MD [and three others]
Zakim and Boyer's hepatology : a textbook of liver disease / / [edited by] Arun J. Sanyal, MBBS, MD [and three others]
Edizione [Seventh edition]
Pubbl/distr/stampa Philadelphia, PA : , : Elsevier, , [2018]
Descrizione fisica 1 online resource (1,380 pages) : color illustrations
Disciplina 616.3/62
Soggetto topico Liver - Diseases
Liver Diseases
ISBN 0-323-44657-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Anatomy and cellular functions of the liver -- Bile acids and bile flow : new functions of old molecules -- Intestinal microbiome and the liver -- The liver as an immune organ -- The liver's response to injury : inflammation and fibrosis -- Stem cells and hepatocyte transplantation -- Approach to jaundice and abnormal liver function test results -- Noninvasive assessment of disease progression -- Molecular and genetics-based diagnostics -- Imaging in assessment of liver disease and lesions -- Evaluation of the hepatic mass -- Assessment of liver histology -- Critical care management of patients with liver disease -- Neurologic consequences of liver disease -- Ascites and hyponatremia -- Portal hypertension related to bleeding -- Renal failure in cirrhosis -- Cardiopulmonary complications of cirrhosis -- The hemostatic and hematopoietic system in liver disease -- Acute liver failure -- Acute-on-chronic liver failure -- Epidemiology and pathogenesis of alcoholic liver disease -- Natural history and cofactors of alcoholic liver disease -- Prevention and management of alcoholic liver disease -- Pathogenesis of nonalcoholic fatty liver disease -- Epidemiology, natural history, and evaluation of nonalcoholic fatty liver disease -- Management of nonalcoholic fatty liver disease and metabolic syndrome -- Virology and pathogenesis of hepatitis C -- Epidemiology, natural history, and diagnosis of hepatitis C -- Treatment of hepatitis C -- Virology and pathogenesis of hepatitis B -- Epidemiology, diagnosis, and natural history of hepatitis B -- Treatment of hepatitis B -- Hepatitis D -- Hepatitis A -- Hepatitis E -- HIV and the liver -- Liver disease associated with systemic viral infection -- Parasitic liver disease -- Bacterial and miscellaneous infections of the liver -- Autoimmune hepatitis -- Primary biliary cholangitis -- Primary and secondary sclerosing cholangitis -- Budd-Chiari syndrome and sinusoidal obstruction syndrome -- Portal and splenic vein thrombosis -- Hepatocellular carcinoma -- Cholangiocarcinoma -- Other malignant hepatic tumors -- Benign liver tumors -- Pretransplant evaluation and care -- Transplantation of the liver -- Post--liver transplant management -- Recurrent primary disease after liver transplantation -- The liver in pregnancy -- Nutrition and the liver -- Drug-induced liver injury -- Preoperative and postoperative hepatic dysfunctions -- Bilirubin metabolism and its disorders -- Wilson disease -- Hemochromatosis -- Α1 -antitrypsin deficiency -- Approach to and evaluation of metabolic liver diseases -- Pediatric cholestatic syndromes -- Fibrocystic diseases of the liver -- Viral hepatitis in children.
Record Nr. UNINA-9910583365903321
Philadelphia, PA : , : Elsevier, , [2018]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui