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Frontiers in pluripotent stem cells research and therapeutic potentials [[electronic resource] ] : bench-to-bedside / / edited by Kuldip S. Sidhu
| Frontiers in pluripotent stem cells research and therapeutic potentials [[electronic resource] ] : bench-to-bedside / / edited by Kuldip S. Sidhu |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Dubai, United Arab Emirates, : Bentham Science, [2012?] |
| Descrizione fisica | 1 online resource (250 p.) |
| Disciplina |
616
616.02774 |
| Altri autori (Persone) | SidhuKuldip S |
| Soggetto topico |
Stem cells - Research
Multipotent stem cells - Research |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 01 Title.pdf; 02 Cover Page; 03 REVISED eBooks End User License Agreement-Website; 04 Dedication; 05 Content; 06 Foreword; 07 Preface; 08 List of Contributors; 09 Chapter 01; 10 Chapter 02; 11 Chapter 03; 12 Chapter 04; 13 Chapter 05; 14 Chapter 06; 15 Chapter 07; 16 Chapter 08; 17 Chapter 09; 18 Chapter 10; 19 Chapter 11; 20 Chapter 12; 21 Chapter 13; 22 Chapter 14; 23 Chapter 15; 24 Chapter 16; 25 Subject |
| Record Nr. | UNINA-9910779023603321 |
| Dubai, United Arab Emirates, : Bentham Science, [2012?] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Frontiers in pluripotent stem cells research and therapeutic potentials [[electronic resource] ] : bench-to-bedside / / edited by Kuldip S. Sidhu
| Frontiers in pluripotent stem cells research and therapeutic potentials [[electronic resource] ] : bench-to-bedside / / edited by Kuldip S. Sidhu |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Dubai, United Arab Emirates, : Bentham Science, [2012?] |
| Descrizione fisica | 1 online resource (250 p.) |
| Disciplina |
616
616.02774 |
| Altri autori (Persone) | SidhuKuldip S |
| Soggetto topico |
Stem cells - Research
Multipotent stem cells - Research |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 01 Title.pdf; 02 Cover Page; 03 REVISED eBooks End User License Agreement-Website; 04 Dedication; 05 Content; 06 Foreword; 07 Preface; 08 List of Contributors; 09 Chapter 01; 10 Chapter 02; 11 Chapter 03; 12 Chapter 04; 13 Chapter 05; 14 Chapter 06; 15 Chapter 07; 16 Chapter 08; 17 Chapter 09; 18 Chapter 10; 19 Chapter 11; 20 Chapter 12; 21 Chapter 13; 22 Chapter 14; 23 Chapter 15; 24 Chapter 16; 25 Subject |
| Record Nr. | UNINA-9910828412603321 |
| Dubai, United Arab Emirates, : Bentham Science, [2012?] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Frontiers in stem cell and regenerative medicine research . Volume 3. / / edited by Atta-ur-Rahman & Shazia Anjum
| Frontiers in stem cell and regenerative medicine research . Volume 3. / / edited by Atta-ur-Rahman & Shazia Anjum |
| Pubbl/distr/stampa | Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2017 |
| Descrizione fisica | 1 online resource (266 pages) : illustrations, tables |
| Disciplina | 616.02774 |
| Collana | Frontiers in Stem Cell and Regenerative Medicine Research |
| Soggetto topico |
Stem cells - Research
Cell membranes - Research |
| ISBN | 1-68108-257-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910164058303321 |
| Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Frontiers in stem cell and regenerative medicine research . Volume 2 / / edited by Atta-ur-Rahman and Shazia Anjum
| Frontiers in stem cell and regenerative medicine research . Volume 2 / / edited by Atta-ur-Rahman and Shazia Anjum |
| Pubbl/distr/stampa | Sharjah, United Arab Emirates : , : Bentham Science Publishers, , [2016] |
| Descrizione fisica | 1 online resource (302 pages) |
| Disciplina | 616.02774 |
| Collana | Frontiers in Stem Cell and Regenerative Medicine Research |
| Soggetto topico |
Stem cells - Research
Regenerative medicine |
| ISBN | 1-68108-183-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover -- Title -- EUL -- Contents -- Preface -- LOC -- Chapter 01 -- Chapter 02 -- Chapter 03 -- Chapter 04 -- Chapter 05 -- Chapter 06 -- Chapter 07 -- Chapter 08 -- Chapter 09 -- Chapter 10 -- Index -- 10 Back. |
| Record Nr. | UNINA-9910797786503321 |
| Sharjah, United Arab Emirates : , : Bentham Science Publishers, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Frontiers in stem cell and regenerative medicine research . Volume 2 / / edited by Atta-ur-Rahman and Shazia Anjum
| Frontiers in stem cell and regenerative medicine research . Volume 2 / / edited by Atta-ur-Rahman and Shazia Anjum |
| Pubbl/distr/stampa | Sharjah, United Arab Emirates : , : Bentham Science Publishers, , [2016] |
| Descrizione fisica | 1 online resource (302 pages) |
| Disciplina | 616.02774 |
| Collana | Frontiers in Stem Cell and Regenerative Medicine Research |
| Soggetto topico |
Stem cells - Research
Regenerative medicine |
| ISBN | 1-68108-183-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover -- Title -- EUL -- Contents -- Preface -- LOC -- Chapter 01 -- Chapter 02 -- Chapter 03 -- Chapter 04 -- Chapter 05 -- Chapter 06 -- Chapter 07 -- Chapter 08 -- Chapter 09 -- Chapter 10 -- Index -- 10 Back. |
| Record Nr. | UNINA-9910814620903321 |
| Sharjah, United Arab Emirates : , : Bentham Science Publishers, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Frontiers in stem cell and regenerative medicine research . Volume 1 / / editors Atta-ur-Rahman, FRS, Kings College, University of Cambridge, Cambridge UK, Shazia Anjum, Department of Chemistry, Cholistan Institute of Desert Studies, The Islamia University of Bahawalpur, Pakistan
| Frontiers in stem cell and regenerative medicine research . Volume 1 / / editors Atta-ur-Rahman, FRS, Kings College, University of Cambridge, Cambridge UK, Shazia Anjum, Department of Chemistry, Cholistan Institute of Desert Studies, The Islamia University of Bahawalpur, Pakistan |
| Pubbl/distr/stampa | Sharjah, United Arab Emirates : , : Bentham Science Publishers Ltd., , 2015 |
| Descrizione fisica | 1 online resource (151 p.) |
| Disciplina | 616.02774 |
| Collana | Frontiers in Stem Cell and Regenerative Medicine Research, Volume 1 |
| Soggetto topico |
Stem cells - Research
Regeneration (Biology) Stem cells - Transplantation |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60805-994-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; Title; EUL; Contents; Preface; List of Contributor; Chapter 01; Chapter 02; Chapter 03; Chapter 04; Chapter 05; Bak Cover |
| Record Nr. | UNINA-9910460876303321 |
| Sharjah, United Arab Emirates : , : Bentham Science Publishers Ltd., , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Frontiers in stem cell and regenerative medicine research . Volume 1 / / editors Atta-ur-Rahman, FRS, Kings College, University of Cambridge, Cambridge UK, Shazia Anjum, Department of Chemistry, Cholistan Institute of Desert Studies, The Islamia University of Bahawalpur, Pakistan
| Frontiers in stem cell and regenerative medicine research . Volume 1 / / editors Atta-ur-Rahman, FRS, Kings College, University of Cambridge, Cambridge UK, Shazia Anjum, Department of Chemistry, Cholistan Institute of Desert Studies, The Islamia University of Bahawalpur, Pakistan |
| Pubbl/distr/stampa | Sharjah, United Arab Emirates : , : Bentham Science Publishers Ltd., , 2015 |
| Descrizione fisica | 1 online resource (151 p.) |
| Disciplina | 616.02774 |
| Collana | Frontiers in Stem Cell and Regenerative Medicine Research, Volume 1 |
| Soggetto topico |
Stem cells - Research
Regeneration (Biology) Stem cells - Transplantation |
| ISBN | 1-60805-994-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; Title; EUL; Contents; Preface; List of Contributor; Chapter 01; Chapter 02; Chapter 03; Chapter 04; Chapter 05; Bak Cover |
| Record Nr. | UNINA-9910797295603321 |
| Sharjah, United Arab Emirates : , : Bentham Science Publishers Ltd., , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Frontiers in stem cell and regenerative medicine research . Volume 1 / / editors Atta-ur-Rahman, FRS, Kings College, University of Cambridge, Cambridge UK, Shazia Anjum, Department of Chemistry, Cholistan Institute of Desert Studies, The Islamia University of Bahawalpur, Pakistan
| Frontiers in stem cell and regenerative medicine research . Volume 1 / / editors Atta-ur-Rahman, FRS, Kings College, University of Cambridge, Cambridge UK, Shazia Anjum, Department of Chemistry, Cholistan Institute of Desert Studies, The Islamia University of Bahawalpur, Pakistan |
| Pubbl/distr/stampa | Sharjah, United Arab Emirates : , : Bentham Science Publishers Ltd., , 2015 |
| Descrizione fisica | 1 online resource (151 p.) |
| Disciplina | 616.02774 |
| Collana | Frontiers in Stem Cell and Regenerative Medicine Research, Volume 1 |
| Soggetto topico |
Stem cells - Research
Regeneration (Biology) Stem cells - Transplantation |
| ISBN | 1-60805-994-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; Title; EUL; Contents; Preface; List of Contributor; Chapter 01; Chapter 02; Chapter 03; Chapter 04; Chapter 05; Bak Cover |
| Record Nr. | UNINA-9910814803903321 |
| Sharjah, United Arab Emirates : , : Bentham Science Publishers Ltd., , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Handbook of Stem Cell Applications [[electronic resource] /] / edited by Khawaja H. Haider
| Handbook of Stem Cell Applications [[electronic resource] /] / edited by Khawaja H. Haider |
| Edizione | [1st ed. 2024.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 |
| Descrizione fisica | 1 online resource (167 illus., 47 illus. in color. eReference.) |
| Disciplina |
571.6
616.02774 |
| Soggetto topico |
Stem cells
Regenerative medicine Nervous system - Diseases Stem Cell Biology Regenerative Medicine and Tissue Engineering Neurological Disorders |
| ISBN | 981-9971-19-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1_ The application of stem cells for the therapy of Parkinson’s disease -- Chapter 2_Stem cell therapy after neurological injuries -- Chapter 3_Strategies of Stem cell therapy in nervous system injuries repair and regeneration -- Chapter 4_Neural regeneration therapies for Alzheimer's and Parkinson's disease-related disorders -- Chapter 5_Emerging Stem Cell Therapy and Tissue Engineering Approaches in Neurodegenerative Diseases -- Chapter 6_Next Generation of Science with Stem Cell-based Neural Organoids -- Chapter 7_Mesenchymal stem cells for ocular disorders -- Chapter 8_Keratocytes evolution in advanced regenerative corneal therapy with keratoconus -- Chapter 9_Latest advances in mesenchymal stem cell-based therapy of eye diseases -- Chapter 10_Stem cells in ophthalmology: from the bench to the bedside -- Chapter 11_Stem cells in periodontal regeneration -- Chapter 12_Dental pulp stem cells in Endodontics – Advances, applications and challenges -- Chapter 13_Significance of inflammatory milieu during regeneration of periodontal tissues using dental mesenchymal stem cell -- Chapter 14_3D bioprinting in conjunction with bone marrow mesenchymal stem cells for the treatment of bone defects -- Chapter 15_Allogenic Stem Cells: Advances in Knee Osteoarthritis -- Chapter 16_Mesenchymal stem cells for bone and cartilage regeneration: state-of-the-art -- Chapter 17_Clinical trials of cell therapy in muscular dystrophies -- Chapter 18_Scaling Stem Cells to Cure Millions of Patients with Diabetes – Approaches, Technology, and Future Directions -- Chapter 19_Restoring β-cells population through in situ differentiation of the resident pancreatic cells -- Chapter 20_Stem Cell-Based Regenerative Therapies for Functional Endocrine System Organs: Tissue Engineering Applications and Future Strategies -- Chapter 21_Recent advance in regenerativemedicine of the liver and bile duct system by chemically induced liver progenitor cells (CLiPs) -- Chapter 22_Advantages of a novel hepatic stem/progenitor cell population for fibrotic/cirrhotic liver repair and regeneration -- Chapter 23_ Evolving Understanding of Renal Progenitor (Stem) Cells in Renal Physiology and Pathophysiology -- Chapter 24_The regenerative potential of human adult renal stem/progenitor cells -- Chapter 25_Role of Exosomes as a biomarker in cardio-metabolic and renal diseases -- Chapter 26_Renovascular applications of stem cells -- Chapter 27_Reversing the aged Immune system with Stem cells -- Chapter 28_Germline stem cell technology in fertility preservation -- Chapter 29_One-stop shop for salivary gland regeneration and other exocrine organs -- Chapter 30_ Epithelial Stem Cell for Regeneration in Acute and Chronic Airway Injury -- Chapter 31_Genetic Cell Therapy in Anti-Aging Regenerative Cosmetology -- Chapter 32_Polytrauma and Stem Cells -- Chapter 33_The Multifaceted Role of Induced Pluripotent Stem Cells in Pre-Clinical Cardiac Regeneration Research -- Chapter 34_Stem cell-based regenerative medicine therapy in cancer -- Chapter 35_Novel Prognostic and Predictive Biomarkers in Oncology -- Chapter 36_Mesenchymal stem cells, cancer stem cells (CSCs), and circulating tumor cells (CTCs): roles and combinations in tumor growth and dissemination -- Chapter 37_ Participation of mesenchymal stem cell in the tumor process -- Chapter 38_Pre-enrichment of Adipose Tissue Grafts with Adipose Derived Stem Cells: Potential and Limitations -- Chapter 39_Matrix mechanical cues affect cell behavior and tissue regeneration -- Chapter 40_Biophysical regulators of mesenchymal stem cell fate -- Chapter 41_Influence of microbiota of donors and recipients in mesenchymal stem cell behavior regarding epigenetic pattern, stemness and secretome -- Chapter 42_Mesenchymal stem cells as modern off-the-shelf products: From research perspectives to clinical practice -- Chapter 43_Application of single-cell sequencing on stem cell research -- Chapter 44_Proteomics investigations on stem cell-based regenerative medicine -- Chapter 45_Phospholipid metabolism in stem cells and its application to pathological analysis -- Chapter 46_The role of stem cells in exercise enhanced organogenesis and regeneration -- Chapter 47_Mesenchymal stem cell-derived exosomes: A novel remedy for the treatment of Parkinson’s Disease -- Chapter 48_Time of cell injection -- Chapter 49_Novel Preconditioning approach to promote donor cell survival. |
| Record Nr. | UNINA-9910845482403321 |
| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Handbook of stem cell therapy . Volume 1. / / edited by Khawaja Husnain Haider
| Handbook of stem cell therapy . Volume 1. / / edited by Khawaja Husnain Haider |
| Pubbl/distr/stampa | Gateway East, Singapore : , : Springer, , [2022] |
| Descrizione fisica | 1 online resource (1527 pages) |
| Disciplina | 616.02774 |
| Soggetto topico |
Stem cells - Transplantation
Regenerative medicine Stem cells |
| ISBN |
9789811926556
9789811926549 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Foreword -- Contents -- About the Editor -- Section Editors -- Contributors -- Part I: Cell-Based Therapy Approach: Mesenchymal Stem Cell-Based Therapy -- 1 Human Mesenchymal Stem Cells: The Art to Use Them in the Treatment of Previously Untreatable -- Introduction -- Mesenchymal Stem Cells Current Status: The ``Problems´´ That in Reality Do Not Exist -- Practical Approaches: The Golden Standards, i.e., ``Good Biological Praxis´´ (GBP) Using the Historical Laboratory Experience -- Data Extrapolation from Small Animal Studies to Humans Is Unfounded and Without Relevance -- Current Research Paradigm: MSCs in Advanced Phases of Clinical Trials Although Understandable Is Far from Personalized Medicine -- A Case of Autologous Versus Allogeneic MSCs, an Unanswered Question -- A Case for Autologous Cells -- Autologous Cells from Patients Are Also ``sick´´ -- Autologous Cells in Elderly Patients Are Also Aged -- A Case for Allogeneic Cells -- Logistic Advantage of Allogenic MSCs -- Allogenic MSCs Overcome the Limitations of Aging and Sickness of Autologous Cells -- Quality Control of MSCs Preparation: A Prerequisite for Optimal Prognosis -- Conclusion -- References -- 2 Sources and Therapeutic Strategies of Mesenchymal Stem Cells in Regenerative Medicine -- Introduction -- Mesenchymal Stem Cells -- Sources of Mesenchymal Stem Cells -- Bone Marrow-Derived MSCs -- Advantages of BM-Derived MSCs -- Limitations of BM-Derived MSCs -- Adipose Tissue-Derived MSCs -- Advantages of Adipose Tissue-Derived MSCs -- Limitations of Adipose Tissue-Derived MSCs -- Isolation of Adipose Tissue-Derived MSCs -- Clinical Applications of Adipose Tissue-Derived MSCs -- Umbilical Cord-Derived MSCs -- Human Umbilical Cord Structure and Function -- Advantages of WJ-Derived MSCs -- Limitations of WJ-Derived MSCs -- Isolation Methods of WJ-Derived MSCs.
Clinical Applications of WJ-Derived MSCs -- Therapeutic Strategies of Using MSCs -- Tissue Regeneration -- Immunomodulation of MSCs -- Extracellular Vesicles/Exosomes Derived from MSCs -- MSCs Act as an Efficient Tool for Gene Therapy -- References -- 3 Considerations for Clinical Use of Mesenchymal Stromal Cells -- Introduction -- Biological Characteristics -- Phenotypic Profile -- MSCs´ Proliferation -- Differentiation Capacity -- Cellular Transformation -- Mechanism of Action -- Cell Migration Toward Damaged Tissues -- Tissue Repair -- Immunomodulatory Potential -- Preclinical Applications -- MSC-Based Therapy for Autoimmune Diseases -- MSCs for Cancer Treatment -- The Anti-tumor Activity of MSCs -- The Pro-tumor Activity of MSCs -- The Imprint of Disease on MSCs -- Considerations for Clinical Applications -- Safety Concerns -- Cell Manufacturing for Clinical Use -- Considerations for Cellular Medicament -- General Considerations -- Attempts to Improve the Therapeutic Outcomes of Cellular Medicament -- Concluding Remarks and Future Perspective -- Cross-References -- References -- 4 Stem Cells in Wound Healing and Scarring -- Introduction -- Wound-Healing Process -- Normal Wound Healing -- Impaired Wound Healing -- Excessive Wound Healing -- Stem Cell Subtypes in Skin Regeneration -- Embryonic Stem Sells -- Induced Pluripotent Stem Cells -- Mesenchymal Stem Cells -- Epithelial (Epidermal) Stem Cells -- Applications in Defective Wound Healing -- Stem Cells in Overscarring -- Stem Cell Therapy in Pathological Scarring -- Conclusion -- Cross-References -- References -- 5 Mesenchymal Stem Cells -- Introduction -- Mesenchymal Stem Cells: Fist Description in Bone Marrow -- Bone Marrow-Derived MSCs -- Isolation of MSCs from Different Sources -- Adipose Tissue -- Umbilical Cord -- Umbilical Cord Blood -- Wharton´s Jelly -- Placenta. Characterization MSCs Before Culture -- STRO-1 -- CD271 -- SSEA-4 -- CD146 -- MSCs in the Clinical Perspective -- MSCs-Based Therapy for Cardiovascular Pathologies -- MSCs-Based Therapy for Acute Graft-Versus-Host Disease -- MSCs-Based Therapy for Crohn´s Disease -- MSCs-Based Therapy for Multiple Sclerosis -- MSCs-Based Therapy for Rheumatoid Arthritis and Osteoarthritis -- Exosomes-Based Therapeutic Intervention -- MSCs-Derived Exosome for Therapy ``Without Cells´´ -- MSCs-Derived Exosomes and Acute Graft-Versus-Host Disease -- MSCs-Derived Exosomes for Inflammatory Bowel Disease -- MSCs-Derived Exosomes for Rheumatoid Arthritis and Knee Osteoarthritis -- MSCs-Derived Exosomes for the Heart -- Multiple Sclerosis -- Conclusion -- References -- 6 Mesenchymal Stromal Cells for COVID-19 Critical Care Patients -- Introduction -- Mechanism of Infection and Immune Response -- The Rationale for the Clinical Use of MSCs for COVID-19 Patients -- Progress in MSC-Based Therapy for COVID-19 -- Other Cell-Based Innovation for COVID-19 -- Side Effects of Mesenchymal Stem Cell-Based Therapy -- Unmet Challenges of Adoptive MSCs Therapy -- Study Design -- Source of Cells -- Route of Cell Administration -- Dosage Strategies -- Risks Associated with Stem Cell Therapy -- Concluding Remarks -- References -- 7 Mesenchymal Stem Cell Therapy for Inflammatory Bowel Disease -- Introduction -- IBD Therapy with MSCs -- MSCs Properties -- Mechanisms of MSCs´ Action -- Preclinical Studies -- MSCs-Derived Exosomes for Experimental IBD Therapy -- Clinical Studies -- Completed Clinical Studies -- Local MSCs Injections -- Intravenous MSCs Administration -- Proceeding Clinical Studies -- Conclusion -- References -- 8 Extracellular Vesicles-Based Cell-Free Therapy for Liver Regeneration -- Introduction -- Liver and Heart Connected and Non-connected Defects. Status on Cell-Based Therapy for Liver Diseases -- Experimental Animal Studies -- Clinical Studies -- Cell-Free Therapy Approaches for the Liver -- Diagnostic and Therapeutic Role of EVs in Liver Diseases -- Conclusion and Future Perspectives -- References -- 9 Current State of Stem Cell Therapy for Heart Diseases -- Introduction -- Aging of the Heart -- Heart Disease -- Conventional Therapies for Heart Disease -- Mechanisms of Action of Stem Cells in Restoring the Heart Function -- Clinical Evidence of Cell-Based Intervention in Ameliorating Heart Disease -- Acute Myocardial Infraction -- Heart Failure -- Refractory Angina -- Limitations of Stem Cell Therapy -- Future Perspectives -- Combination with Gene Therapy -- Exosomes -- Biomaterials -- Conclusion -- Cross-References -- References -- 10 Mesenchymal Stem Cells for Cardiac Repair -- Introduction -- BM-Derived MSCs -- Isolation and Characterization of MSCs -- Important Characteristics of MSCs -- Differentiation Potential of MSCs -- Trophic Functions of MSCs -- Immunomodulatory Characters of MSCs -- Preclinical Studies with MSCs -- Small Experimental Animal Studies -- Large Animal Experimental Models: Translational Studies -- MSCs in the Clinical Perspective -- Randomized Clinical Trials with Autologous or Allogenic BM-Derived MSCs -- The POSEIDON Trial -- The PROMETHEUS Clinical Trial -- The TAC-HTF Clinical Trial -- Mesenchymal Stromal Cell for IHD -- Intravenous Allogenic MSC Nonischemic Cardiomyopathy -- Conclusions and Future Perspective -- References -- 11 Preclinical Research of Mesenchymal Stem Cell-Based Therapy for Ocular Diseases -- Introduction -- Models of Corneal Diseases -- Models of Lens Diseases -- Retinal Models -- Model Damage to the N-methyl-d-aspartate Receptor (NMDA) -- Models of Transient Ischemia -- Transgenic RGC Loss Models. Model of Experimental Autoimmune Encephalopathy (EAE) -- Models of Hereditary Diseases Associated with Optic Nerve Damage -- Glaucoma Models -- Animal Models of Primary Angle-Closure Glaucoma (PACG) -- References -- 12 Stem Cell for Cartilage Repair -- Introduction -- Cartilage -- Chondrocyte -- Collagen -- Fluid -- Chondrocyte Degeneration and Loss of Articular Cartilage -- The Articular Cartilage Defects Treatments -- Traditional Surgical Regeneration Techniques -- Microfracture -- Osteochondral Transplantation (OCT) -- Osteochondral Autologous Transplantation (OAT) -- Osteochondral Allograft Transplantation (OCA) -- Particulated Articular Cartilage Implantation (PACI) -- Tissue-Engineered Articular Cartilage -- ``Cell-Scaffold Construct´´ Strategies -- Cell-Free Strategies -- Scaffold-Free Strategies -- Common Cell Types for Articular Cartilage Regeneration -- Mature Cells -- Stem Cells -- Mesenchymal Stem Cells -- BM-MSCs -- WJ-MSCs -- UCB-MSCs -- SMSCs/SF-MSCs -- Adipose Tissue-Derived MSCs -- PB-MSCs -- Scaffolds for Cartilage Treatment -- Bioreactors -- Spinner Flasks -- Rotating Wall Vessels -- Perfusion Bioreactors -- Magnetic Field Bioreactors -- Ultrasonic Bioreactors -- Conclusion -- Cross-References -- References -- 13 Direct Reprogramming Strategies for the Treatment of Nervous System Injuries and Neurodegenerative Disorders -- Introduction -- Direct Neural Reprogramming Strategies -- Reprogramming Factors -- Transcription Factors -- miRNA -- Small Molecules -- Approaches for Determining the Optimal Combination of Reprogramming Factors -- Comparative Gene Expression Analyses -- Trial and Error Screening of Libraries -- CRISPR Activation-Based Screening -- Employing Single-Cell RNAseq and Computational Analysis -- Implications of the Cell Source -- Fibroblasts -- Astrocytes -- Hepatocytes -- Pericytes -- Urine Epithelial Cells. Generation of Distinct Neural Cell Subtypes. |
| Record Nr. | UNINA-9910624315803321 |
| Gateway East, Singapore : , : Springer, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
