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Peptides as drugs [[electronic resource] ] : discovery and development / / edited by Bernd Groner
| Peptides as drugs [[electronic resource] ] : discovery and development / / edited by Bernd Groner |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2009 |
| Descrizione fisica | 1 online resource (244 p.) |
| Disciplina |
615.19
615.3 |
| Altri autori (Persone) | GronerB (Bernd) |
| Soggetto topico |
Drugs - Design
Peptide drugs |
| ISBN |
1-282-46085-4
9786612460852 3-527-62684-0 3-527-62683-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Peptides as Drugs; Contents; Preface; List of Contributors; 1: Peptides as Drugs: Discovery and Development; 1.1 Discovery of New Potential Drug Targets and the Limitations of Druggability; 1.2 Protein Interaction Domains Are at the Core of Signaling Pathways; 1.3 Peptides as Inhibitors of Protein Interactions; References; 2: Mimics of Growth Factors and Cytokines; 2.1 Introduction; 2.2 The Cytokines; 2.2.1 The Receptors; 2.2.2 "Simple" Receptors; 2.2.3 "Complex" Receptors; 2.3 Defining Receptor Recognition Sites in Cytokines Using Chimeric Proteins
2.4 Receptor Recognition Sites are Organized as Exchangeable Modules2.5 The Concept of Fusing the Cytokine to the Soluble Receptor: Hyper-IL-6; 2.6 Antagonists Specifically Inhibiting IL-6 Trans-Signaling; 2.7 In Vitro Evolution of Peptides and Proteins; 2.7.1 Platforms for the Selection of High-Affinity Binders; 2.7.2 Agonists and Antagonists of Cytokines and Growth Hormones; 2.8 Concluding Remarks; References; 3: Peptides Derived from Exon v6 of the CD44 Extracellular Domain Prevent Activation of Receptor Tyrosine Kinases and Subsequently Angiogenesis and Metastatic Spread of Tumor Cells 3.1 Introduction3.2 CD44 Proteins and Their Involvement in RTK Activation; 3.3 CD44v6 Acts as a Coreceptor for c-Met and Ron; 3.4 Three Amino Acids in CD44 Exon v6 Are Crucial for the CD44v6 Coreceptor Function, and Small Peptides Can Interfere with This Function; 3.5 The Ectodomain of CD44v6 Binds to HGF; 3.6 Peptides Corresponding to Exon v6 of CD44 Inhibit Metastatic Spread of Tumor Cells; 3.7 The Significance of the Collaboration between CD44v6 and c-Met In Vivo; 3.8 The CD44v6 Peptides Interfere with Angiogenesis; 3.9 Outlook; References 4: Peptide Aptamers Targeting the Viral E6 Oncoprotein Induce Apoptosis in HPV-positive Cancer Cells4.1 Human Papillomaviruses and Oncogenesis; 4.1.1 Cervical Cancer; 4.1.2 The E6 and E7 Genes; 4.2 Peptide Aptamers Targeting the HPV E6 Oncoprotein; 4.3 E6-Targeting Peptide Aptamers: Therapeutic Perspectives; 4.3.1 Therapeutic Target Protein Evaluation by Peptide Aptamers; 4.3.2 The Intrinsic Therapeutic Potential of Peptide Aptamers; 4.3.3 Identification of Functional Peptide Mimics by Displacement Screening; 4.4 Perspectives; References 5: The Prevention of HIV Infection with Viral Entry Inhibitors5.1 Introduction: The Potential of Peptides as Drugs in the Treatment of HIV Infection; 5.2 The HIV Entry Process; 5.3 Peptides that Inhibit Receptor or Coreceptor Binding; 5.3.1 Physiological Antimicrobial Peptides; 5.3.1.1 Defensins; 5.3.2 Chemokines; 5.3.3 Synthetic Peptides and Peptidomimetics; 5.4 Inhibitors of the Viral and Cellular Membrane Fusion Process; 5.5 Entry Inhibitory Peptides Selected by the Phage Display Technology; 5.6 Limitations of Peptides in the Treatment of HIV Infection 5.7 Strategies to Prolong the In Vivo Half-Life of Antiviral Peptides |
| Record Nr. | UNINA-9910841266003321 |
| Weinheim, : Wiley-VCH, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pharmaceutical biotechnology : an introduction for pharmacists and pharmaceutical scientists / Daan J. A. Crommelin and Robert D. Sindelar ; edited by Daan J. A. Crommelin and Robert D. Sindelar
| Pharmaceutical biotechnology : an introduction for pharmacists and pharmaceutical scientists / Daan J. A. Crommelin and Robert D. Sindelar ; edited by Daan J. A. Crommelin and Robert D. Sindelar |
| Edizione | [2. ed.] |
| Pubbl/distr/stampa | London ; New York : Routledge, copyr. 2002 |
| Descrizione fisica | XXX, 425 p. : ill. ; 28 cm |
| Disciplina | 615.3 |
| Soggetto topico | Biotecnologia - Impiego in farmacologia |
| ISBN | 0-415-28501-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-990001176230203316 |
| London ; New York : Routledge, copyr. 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Pharmaceutical formulation development of peptides and proteins / edited by Sven Frokjaer and Lars Hovgaard
| Pharmaceutical formulation development of peptides and proteins / edited by Sven Frokjaer and Lars Hovgaard |
| Pubbl/distr/stampa | London ; New York : Taylor & Francis, copyr. 2000 |
| Descrizione fisica | XVII, 238 p. : ill. ; 25 cm |
| Disciplina | 615.3 |
| Soggetto topico |
Proteine - Impiego terapeutico
Peptidi - Impiego terapeutico |
| ISBN | 0-748-40745-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-990001171150203316 |
| London ; New York : Taylor & Francis, copyr. 2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Pneumococcal Vaccines : The Impact of Conjugate Vaccines / / edited by George R. Siber, Keith P. Klugman, P. Helena Mäkelä
| Pneumococcal Vaccines : The Impact of Conjugate Vaccines / / edited by George R. Siber, Keith P. Klugman, P. Helena Mäkelä |
| Pubbl/distr/stampa | Hoboken : , : John Wiley & Sons, Inc., , 2014 |
| Descrizione fisica | 1 online resource (xix, 449 pages) : illustrations |
| Disciplina | 615.3 |
| Soggetto topico | Pneumococcal vaccine |
| ISBN | 1-68367-150-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910830971903321 |
| Hoboken : , : John Wiley & Sons, Inc., , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Polysaccharide-based nanocrystals : chemistry and applications / / edited by Jin Huang [and three others]
| Polysaccharide-based nanocrystals : chemistry and applications / / edited by Jin Huang [and three others] |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH : , : Chemical Industry Press, , 2015 |
| Descrizione fisica | 1 online resource (328 p.) |
| Disciplina | 615.3 |
| Soggetto topico |
Carbohydrate drugs
Polymeric drug delivery systems Polysaccharides |
| ISBN |
3-527-68938-9
3-527-68937-0 3-527-68939-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Polysaccharide-Based Nanocrystals; Contents; List of Contributors; Foreword; Preface; Chapter 1 Polysaccharide Nanocrystals: Current Status and Prospects in Material Science; 1.1 Introduction to Polysaccharide Nanocrystals; 1.2 Current Application of Polysaccharide Nanocrystals in Material Science; 1.3 Prospects for Polysaccharide Nanocrystal-Based Materials; List of Abbreviations; References; Chapter 2 Structure and Properties of Polysaccharide Nanocrystals; 2.1 Introduction; 2.2 Cellulose Nanocrystals; 2.2.1 Preparation of Cellulose Nanocrystals
2.2.1.1 Acid Hydrolysis Extraction of Cellulose Nanocrystals2.2.1.2 Effects of Acid Type; 2.2.1.3 Effects of Pretreatment; 2.2.2 Structure and Properties of Cellulose Nanocrystals; 2.2.2.1 Structure and Rigidity of Cellulose Nanocrystals; 2.2.2.2 Physical Properties of Cellulose Nanocrystals; 2.3 Chitin Nanocrystals; 2.3.1 Preparation of Chitin Nanocrystals; 2.3.1.1 Extraction of Chitin Nanocrystals by Acid Hydrolysis; 2.3.1.2 Extraction of Chitin Nanocrystals by TEMPO Oxidation; 2.3.2 Structure and Properties of Chitin Nanocrystals; 2.3.2.1 Structure and Rigidity of Chitin Nanocrystals 2.3.2.2 Properties of Chitin Nanocrystal Suspensions2.4 Starch Nanocrystals; 2.4.1 Preparation of Starch Nanocrystals; 2.4.1.1 Extraction of Starch Nanocrystals by Acid Hydrolysis; 2.4.1.2 Effect of Ultrasonic Treatment; 2.4.1.3 Effect of Pretreatment; 2.4.2 Structure and Properties of Starch Nanocrystals; 2.4.2.1 Structure of Starch Nanocrystals; 2.4.2.2 Properties of Starch Nanocrystal Suspensions; 2.5 Conclusion and Prospects; List of Abbreviations; References; Chapter 3 Surface Modification of Polysaccharide Nanocrystals; 3.1 Introduction 3.2 Surface Chemistry of Polysaccharide Nanocrystals3.2.1 Surface Hydroxyl Groups; 3.2.2 Surface Groups Originating from Various Extraction Methods; 3.3 Approaches and Strategies for Surface Modification; 3.3.1 Purpose and Challenge of Surface Modification; 3.3.2 Comparison of Different Approaches and Strategies of Surface Modification; 3.4 Adsorption of Surfactant; 3.4.1 Anionic Surfactant; 3.4.2 Cationic Surfactant; 3.4.3 Nonionic Surfactant; 3.5 Hydrophobic Groups Resulting from Chemical Derivatization; 3.5.1 Acetyl and Ester Groups with Acetylation and Esterification 3.5.2 Carboxyl Groups Resulting from TEMPO-Mediated Oxidation3.5.3 Derivatization with Isocyanate Carboamination; 3.5.4 Silyl Groups Resulting from Silylation; 3.5.5 Cationic Groups Resulting from Cationization; 3.6 Polymeric Chains from Physical Absorption or Chemical Grafting; 3.6.1 Hydrophilic Polymer; 3.6.2 Polyester; 3.6.3 Polyolefin; 3.6.4 Block Copolymer; 3.6.5 Polyurethane and Waterborne Polyurethane; 3.6.6 Other Hydrophobic Polymer; 3.7 Advanced Functional Groups and Modification; 3.7.1 Fluorescent and Dye Molecules; 3.7.2 Amino Acid and DNA 3.7.3 Self-Cross-linking of Polysaccharide Nanocrystals |
| Record Nr. | UNINA-9910140485003321 |
| Weinheim, Germany : , : Wiley-VCH : , : Chemical Industry Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Polysaccharide-based nanocrystals : chemistry and applications / / edited by Jin Huang [and three others]
| Polysaccharide-based nanocrystals : chemistry and applications / / edited by Jin Huang [and three others] |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH : , : Chemical Industry Press, , 2015 |
| Descrizione fisica | 1 online resource (328 p.) |
| Disciplina | 615.3 |
| Soggetto topico |
Carbohydrate drugs
Polymeric drug delivery systems Polysaccharides |
| ISBN |
3-527-68938-9
3-527-68937-0 3-527-68939-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Polysaccharide-Based Nanocrystals; Contents; List of Contributors; Foreword; Preface; Chapter 1 Polysaccharide Nanocrystals: Current Status and Prospects in Material Science; 1.1 Introduction to Polysaccharide Nanocrystals; 1.2 Current Application of Polysaccharide Nanocrystals in Material Science; 1.3 Prospects for Polysaccharide Nanocrystal-Based Materials; List of Abbreviations; References; Chapter 2 Structure and Properties of Polysaccharide Nanocrystals; 2.1 Introduction; 2.2 Cellulose Nanocrystals; 2.2.1 Preparation of Cellulose Nanocrystals
2.2.1.1 Acid Hydrolysis Extraction of Cellulose Nanocrystals2.2.1.2 Effects of Acid Type; 2.2.1.3 Effects of Pretreatment; 2.2.2 Structure and Properties of Cellulose Nanocrystals; 2.2.2.1 Structure and Rigidity of Cellulose Nanocrystals; 2.2.2.2 Physical Properties of Cellulose Nanocrystals; 2.3 Chitin Nanocrystals; 2.3.1 Preparation of Chitin Nanocrystals; 2.3.1.1 Extraction of Chitin Nanocrystals by Acid Hydrolysis; 2.3.1.2 Extraction of Chitin Nanocrystals by TEMPO Oxidation; 2.3.2 Structure and Properties of Chitin Nanocrystals; 2.3.2.1 Structure and Rigidity of Chitin Nanocrystals 2.3.2.2 Properties of Chitin Nanocrystal Suspensions2.4 Starch Nanocrystals; 2.4.1 Preparation of Starch Nanocrystals; 2.4.1.1 Extraction of Starch Nanocrystals by Acid Hydrolysis; 2.4.1.2 Effect of Ultrasonic Treatment; 2.4.1.3 Effect of Pretreatment; 2.4.2 Structure and Properties of Starch Nanocrystals; 2.4.2.1 Structure of Starch Nanocrystals; 2.4.2.2 Properties of Starch Nanocrystal Suspensions; 2.5 Conclusion and Prospects; List of Abbreviations; References; Chapter 3 Surface Modification of Polysaccharide Nanocrystals; 3.1 Introduction 3.2 Surface Chemistry of Polysaccharide Nanocrystals3.2.1 Surface Hydroxyl Groups; 3.2.2 Surface Groups Originating from Various Extraction Methods; 3.3 Approaches and Strategies for Surface Modification; 3.3.1 Purpose and Challenge of Surface Modification; 3.3.2 Comparison of Different Approaches and Strategies of Surface Modification; 3.4 Adsorption of Surfactant; 3.4.1 Anionic Surfactant; 3.4.2 Cationic Surfactant; 3.4.3 Nonionic Surfactant; 3.5 Hydrophobic Groups Resulting from Chemical Derivatization; 3.5.1 Acetyl and Ester Groups with Acetylation and Esterification 3.5.2 Carboxyl Groups Resulting from TEMPO-Mediated Oxidation3.5.3 Derivatization with Isocyanate Carboamination; 3.5.4 Silyl Groups Resulting from Silylation; 3.5.5 Cationic Groups Resulting from Cationization; 3.6 Polymeric Chains from Physical Absorption or Chemical Grafting; 3.6.1 Hydrophilic Polymer; 3.6.2 Polyester; 3.6.3 Polyolefin; 3.6.4 Block Copolymer; 3.6.5 Polyurethane and Waterborne Polyurethane; 3.6.6 Other Hydrophobic Polymer; 3.7 Advanced Functional Groups and Modification; 3.7.1 Fluorescent and Dye Molecules; 3.7.2 Amino Acid and DNA 3.7.3 Self-Cross-linking of Polysaccharide Nanocrystals |
| Record Nr. | UNINA-9910814265203321 |
| Weinheim, Germany : , : Wiley-VCH : , : Chemical Industry Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Protein therapeutics / / edited by Tristan Vaughan, Jane Osbourn, and Bahija Jallal
| Protein therapeutics / / edited by Tristan Vaughan, Jane Osbourn, and Bahija Jallal |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH, , 2017 |
| Descrizione fisica | 1 online resource (718 pages) |
| Disciplina | 615.3 |
| Collana | Methods and Principles in Medicinal Chemistry |
| Soggetto topico |
Protein drugs
Proteins - Therapeutic use Proteins - therapeutic use Protein Engineering - methods Proteins - pharmacology |
| ISBN |
3-527-69914-7
3-527-69913-9 3-527-69912-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910270894403321 |
| Weinheim, Germany : , : Wiley-VCH, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Protein therapeutics / / edited by Tristan Vaughan, Jane Osbourn, and Bahija Jallal
| Protein therapeutics / / edited by Tristan Vaughan, Jane Osbourn, and Bahija Jallal |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH, , 2017 |
| Descrizione fisica | 1 online resource (718 pages) |
| Disciplina | 615.3 |
| Collana | Methods and Principles in Medicinal Chemistry |
| Soggetto topico |
Protein drugs
Proteins - Therapeutic use Proteins - therapeutic use Protein Engineering - methods Proteins - pharmacology |
| ISBN |
3-527-69914-7
3-527-69913-9 3-527-69912-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910830404903321 |
| Weinheim, Germany : , : Wiley-VCH, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Protein-based therapeutics / / Dev Bukhsh Singh and Timir Tripathi, editors
| Protein-based therapeutics / / Dev Bukhsh Singh and Timir Tripathi, editors |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore Pte Ltd, , [2023] |
| Descrizione fisica | 1 online resource (387 pages) |
| Disciplina | 615.3 |
| Soggetto topico |
Protein drugs
Proteins |
| ISBN | 981-19-8249-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1_Introduction to Protein Therapeutics. -- Chapter 2_Clinical Applications of Protein-based Therapeutics Against Various Diseases. -- Chapter 3_Protein Engineering Methods for the Design of Protein Therapeutics -- Chapter 4_Recombinant Production of Therapeutic Proteins -- Chapter 5_Antibodies as Protein Therapeutics -- Chapter 6_Streptokinase: The Success Story of a Therapeutic Protein -- Chapter 7_Strategies for Formulation and Systemic Delivery of Therapeutic Proteins -- Chapter 8_Approved Protein Therapeutics and Their Biochemical Targets -- Chapter 9_Pharmacogenetic Biomarkers of Protein Therapeutics -- Chapter 10_Immunogenicity of Therapeutic Proteins -- Chapter 11_Efficacy and Safety Issues of Therapeutic Proteins -- Chapter 12_Emerging Trends, Challenges, and Opportunities in Protein Therapeutics -- Chapter 13_Biosimilar, Biobetter & Biosuperior Therapeutic Proteins -- Chapter 14_Therapeutic Protein-based Vaccines. |
| Record Nr. | UNINA-9910678257903321 |
| Singapore : , : Springer Nature Singapore Pte Ltd, , [2023] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The biosynthesis of natural products : an introduction to secondary metabolism / John D. Bu'Lock
| The biosynthesis of natural products : an introduction to secondary metabolism / John D. Bu'Lock |
| Autore | Bu'lock, John Desmond |
| Pubbl/distr/stampa | London [etc.], : McGraw-Hill, ©1965 |
| Descrizione fisica | x, 149 p. : ill. ; 24 cm |
| Disciplina | 615.3 |
| Soggetto non controllato | Biosintesi |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-990001452520403321 |
Bu'lock, John Desmond
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| London [etc.], : McGraw-Hill, ©1965 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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