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Steroids and terpenoids / edited by Raymond B. Clayton
| Steroids and terpenoids / edited by Raymond B. Clayton |
| Pubbl/distr/stampa | New York ; London : Academic press, 1969 |
| Descrizione fisica | xvii, 903 p. ; 24 cm |
| Disciplina | 615 |
| Altri autori (Persone) | Clayton, Raymond B. |
| Collana | Methods in enzymology ; 015 |
| Soggetto topico |
Steroidi
Terpenoidi |
| ISBN | 0121818721 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISALENTO-991003266079707536 |
| New York ; London : Academic press, 1969 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
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Streptomicina e tubercolosi : aspetti biologici e clinici / A. Omodei Zorini, C. Cattaneo
| Streptomicina e tubercolosi : aspetti biologici e clinici / A. Omodei Zorini, C. Cattaneo |
| Autore | Omodei-Zorini, Attilio |
| Pubbl/distr/stampa | Roma : Sansoni, 1950 |
| Descrizione fisica | 520 p. ; 21 cm |
| Disciplina | 615 |
| Altri autori (Persone) |
Cattaneo, Carlo |
| Collana | Il pensiero scientifico |
| Soggetto non controllato |
Antibiotici
Streptomicina Farmacologia Medicina |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ita |
| Record Nr. | UNINA-990002066800403321 |
Omodei-Zorini, Attilio
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| Roma : Sansoni, 1950 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Stress Responses in Plants : Mechanisms of Toxicity and Tolerance / / edited by Bhumi Nath Tripathi, Maria Müller
| Stress Responses in Plants : Mechanisms of Toxicity and Tolerance / / edited by Bhumi Nath Tripathi, Maria Müller |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (293 p.) |
| Disciplina |
570
571.2 572572 615 |
| Soggetto topico |
Plant physiology
Plant biochemistry Pharmacology Plant Physiology Plant Biochemistry Pharmacology/Toxicology |
| ISBN | 3-319-13368-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Introduction to stress in plants -- Mechanism of heavy metal toxicity and tolerance -- Mechanism of aluminium toxicity and tolerance -- Mechanism of arsenic toxicity and tolerance -- Mechanism of salt toxicity and tolerance -- Mechanism of drought stress and tolerance -- Mechanism of light stress and tolerance -- Mechanism of temperature stress and tolerance -- Mechanism of flood stress and tolerance -- Mechanism of UV-B stress and tolerance. |
| Record Nr. | UNINA-9910298295803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Suolo, acqua / Vincenzo De Giaxa
| Suolo, acqua / Vincenzo De Giaxa |
| Autore | De Giaxa, Vincenzo |
| Edizione | [5. ed.] |
| Pubbl/distr/stampa | Milano : Vallardi, 1912 |
| Descrizione fisica | VIII, 1037 p., 6 p. di tav. : ill. ; 24 cm |
| Disciplina | 615 |
| Soggetto non controllato | Igiene |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ita |
| Record Nr. | UNINA-990001508330403321 |
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De Giaxa, Vincenzo
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| Milano : Vallardi, 1912 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthese et etude des proprietes de sucres halogenes insatures, ramifies, et de certains de leurs nucleosides / Dominique Schwarzenbach
| Synthese et etude des proprietes de sucres halogenes insatures, ramifies, et de certains de leurs nucleosides / Dominique Schwarzenbach |
| Autore | Schwarzenbach, Dominique |
| Pubbl/distr/stampa | Geneve : Universite, 1976 |
| Descrizione fisica | 175 p. ; 24 cm |
| Disciplina | 615 |
| Soggetto non controllato | Farmacologia |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | fre |
| Record Nr. | UNINA-990001647690403321 |
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Schwarzenbach, Dominique
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| Geneve : Universite, 1976 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthese et etudes pharmacologiques de quelques nouveaux antiepileptiques et antispasmodiques : these... / Philippe Gold Aubert
| Synthese et etudes pharmacologiques de quelques nouveaux antiepileptiques et antispasmodiques : these... / Philippe Gold Aubert |
| Autore | Gold Aubert, Philippe |
| Pubbl/distr/stampa | Geneve : Editions Medicine et Hygiene, 1958 |
| Descrizione fisica | 106 p. ; 23 cm |
| Disciplina | 615 |
| Soggetto non controllato | Farmacologia |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | fre |
| Record Nr. | UNINA-990001641160403321 |
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Gold Aubert, Philippe
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| Geneve : Editions Medicine et Hygiene, 1958 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthese et proprietes de nouveaux types de sucres soufres / Hansjorg Eder
| Synthese et proprietes de nouveaux types de sucres soufres / Hansjorg Eder |
| Autore | Eder, Hansjorg |
| Pubbl/distr/stampa | Genève : Editions Médicine et Hygiène, 1979 |
| Descrizione fisica | 273 p. ; 23 cm |
| Disciplina | 615 |
| Soggetto non controllato | Farmacologia |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | fre |
| Record Nr. | UNINA-990001641210403321 |
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Eder, Hansjorg
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| Genève : Editions Médicine et Hygiène, 1979 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tactics in Contemporary Drug Design / / edited by Nicholas A. Meanwell
| Tactics in Contemporary Drug Design / / edited by Nicholas A. Meanwell |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (400 p.) |
| Disciplina |
54
611.01816 615 615.19 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Molecular biology Pharmacology Medicinal Chemistry Molecular Medicine Pharmacology/Toxicology |
| ISBN | 3-642-55041-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Preface to the Series; Preface; Contents; Physical Properties in Drug Design; 1 Introduction: The Realisation of Physical Property Issues; 1.1 Molecular Obesity and Obsession with Potency; 1.2 Med Chem Inflates Properties: The Body Doesn´t Change; 2 Physical Properties: What Are They and Which Are Important?; 2.1 Lipophilicity/Hydrophobicity; 2.1.1 Small Hydrophilic Molecules: A Forgotten Strategy for Oral Medicines?; 2.1.2 Methods for the Measurement and Prediction of Lipophilicity; 2.1.3 Octanol Water Methods: Issues with Overly Lipophilic Compounds
2.1.4 Measurements Using Chromatographic Methods2.2 Acid/Base Strength: pKa; 2.2.1 Measurement and Calculation of pKa; 2.3 Solubility; 2.3.1 The General Solubility Equation; 2.3.2 Simulated Gastrointestinal Fluids; 2.4 Escape from Flatland and the Impact of Aromatic Ring Count; 2.4.1 Lipophilicity and Aromaticity Act in Unison; 3 How the Physical Environment of a Drug Changes from Administration to Target; 3.1 The Passage Through the Body for an Oral Medicine; 3.2 Oral Developability Classification System: Dose, Solubility and Permeation 4 Impact of Physical Properties on Developability and DMPK Parameters4.1 General Aspects of Lipophilicity-Dependent Behaviour; 4.2 Impact of logP, logDpH and Aromaticity on Particular Parameters; 4.2.1 Permeability; 4.2.2 Cytochrome P450s; 4.2.3 hERG Binding; 4.2.4 Promiscuity; 4.2.5 Human Serum Albumin Binding; 4.2.6 Intrinsic Clearance; 4.3 The Composite Risks of Poor Physical Profiles; 5 Efficiency Metrics and Their Interrelationship with Physical Properties; 5.1 Drug Efficiency; 5.1.1 Physical Estimates of Drug Efficiency; 5.2 Ligand Efficiency and Related Measures 5.3 Ligand Lipophilicity Efficiency Measures5.4 The Combined Influence of Efficiency Metrics and Physical Property Measures; 5.5 The Thermodynamics of Efficient Binding; 6 Conclusions; References; Improving Solubility via Structural Modification; 1 Introduction; 2 Description of Aqueous Solubility; 2.1 Definition of Solubility; 2.2 General Solubility Equation; 2.3 Solvation of Organic Molecules; 2.3.1 Effect of Molecular Size and Shape on Solvation; 2.3.2 Water-Solute Hydrogen Bonding; 2.4 Crystal Lattice Stability and Packing Efficiency; 2.4.1 Effect of Molecular Shape on Packing Efficiency 2.4.2 Intermolecular Interactions in the Solid State2.4.3 The Effect of Molecular Symmetry on Crystal Packing; 3 Tactics for Improving Solubility; 3.1 Reducing LogP; 3.1.1 Introducing a Solubilizing Appendage; Introducing Basic Appendages; Introducing Acidic Appendages; Introduction of Neutral Appendages; 3.1.2 Template and Substituent Modifications; Substituent Modifications; Analysis of Substituent Effects on Solubility; The Dual Nature of Fluorine; Intramolecular Interactions; Examples of Substituent Modifications; Template Modifications; 3.2 Disrupting Crystal Lattice Stability 3.2.1 Disruption of Intermolecular H-Bonding Interactions |
| Record Nr. | UNINA-9910298633703321 |
| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Il talidomide e il potere dell'industria farmaceutica. E in Italia? / di Giulio A. Maccacaro
| Il talidomide e il potere dell'industria farmaceutica. E in Italia? / di Giulio A. Maccacaro |
| Autore | Sjostrom, Henning |
| Pubbl/distr/stampa | Milano : Feltrinelli, 1973 |
| Descrizione fisica | XXVII, 248 p. ; 21 cm. |
| Disciplina | 615 |
| Altri autori (Persone) |
Nilsson, Robert
Wolf Belfiore, Annalise Maccacaro, Giulio A. Belfiore, Furio |
| Collana | Medicina e potere |
| Soggetto topico | Talidomide |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ita |
| Record Nr. | UNISALENTO-991000358589707536 |
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Sjostrom, Henning
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| Milano : Feltrinelli, 1973 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
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Target organ toxicology in caenorhabditis elegans / / Dayong Wang
| Target organ toxicology in caenorhabditis elegans / / Dayong Wang |
| Autore | Wang Dayong |
| Pubbl/distr/stampa | Singapore : , : Springer, , 2019 |
| Descrizione fisica | 1 online resource (XIII, 337 p. 232 illus., 175 illus. in color.) |
| Disciplina | 615 |
| Soggetto topico | Target organs (Anatomy) |
| ISBN | 981-13-6010-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Protective Responses of Different Organs to Environmental Toxicants or Stresses -- Avoidance Behaviour of Nematodes to Environmental Toxicants or Stresses -- Intestinal Barrier for Nematodes against Toxicity of Environmental Toxicants or Stresses -- Epidermal Barrier for Nematodes against Toxicity of Environmental Toxicants or Stresses -- Toxicity Induction in Intestine and Epidermis in Nematodes Exposed to Environmental Toxicants or Stresses -- Toxicity Induction in Neurons and Muscle in Nematodes Exposed to Environmental Toxicants or Stresses -- Reproductive Toxicity Induction in Nematodes Exposed to Environmental Toxicants or Stresses -- Intestinal Signalling Pathways Required for the Regulation of Toxicity of Environmental Toxicants or Stresses -- Epidermal Signalling Pathways Required for the Regulation of Toxicity of Environmental Toxicants or Stresses -- Neuronal Signalling Pathways Required for the Regulation of Toxicity of Environmental Toxicants or Stresses -- Germline Signalling Pathways Required for the Regulation of Toxicity of Environmental Toxicants or Stresses. |
| Record Nr. | UNINA-9910350360103321 |
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Wang Dayong
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| Singapore : , : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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