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Strategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment / / edited by Mitchell S. Anscher, Kristoffer Valerie
| Strategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment / / edited by Mitchell S. Anscher, Kristoffer Valerie |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (VI, 305 p. 65 illus., 53 illus. in color.) |
| Disciplina | 614.5999 |
| Soggetto topico |
Cancer research
Cancer Research |
| ISBN | 3-319-45594-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Mechanisms of Normal Tissue Response -- 2. The Role of Hypoxia in Radiation Response -- 3. The Role of Cancer Stem Cells in Tumour Radioresponse -- 4. Novel Strategies to Prevent, Mitigate or Reverse Radiation Injury and Fibrosis -- 5. Technology Based Strategies to Enhance the Therapeutic Ratio -- 6. Nitric Oxide Synthase Uncoupling in Tumor Progression and Cancer Therapy -- 7. Aiming the Immune System to Improve the Antitumor Efficacy of Radiation Therapy -- 8. The Role of MicroRNAs in modulating Tissue Response to Radiation -- 9. Adapting Therapy Based on Tumor Response -- 10. NQO1 Bioactivatable Drugs Modify Radiation Responses -- 11. DNA Repair Pathways as a Potential Target for Radiosensitization -- 12. Radiosensitizing Glioma by Targeting ATM with Small Molecule Inhibitors. |
| Record Nr. | UNINA-9910136004503321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Stress Response Pathways in Cancer [[electronic resource] ] : From Molecular Targets to Novel Therapeutics / / edited by Georg T. Wondrak
| Stress Response Pathways in Cancer [[electronic resource] ] : From Molecular Targets to Novel Therapeutics / / edited by Georg T. Wondrak |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (450 p.) |
| Disciplina |
571.6
610 614.5999 616994 |
| Soggetto topico |
Cancer research
Cell biology Oncology Cancer Research Cell Biology Oncology |
| ISBN | 94-017-9421-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Introduction to cell stress responses in cancer: The big picture -- DNA repair dysregulation in cancer: From molecular mechanisms to synthetic-lethal opportunities -- Cell cycle checkpoint defects as anticancer targets: From molecular mechanisms to therapeutic opportunities -- p53 at the crossroads between stress response signaling and tumorigenesis: From molecular mechanisms to therapeutic opportunities -- Sirtuins as a double-edged sword in cancer: From molecular mechanisms to therapeutic opportunities -- MicroRNA regulated stress responses in cancer -- Senescence in oncogenesis: From molecular mechanisms to therapeutic opportunities -- Pro-senescence therapy for cancer: time for the clinic -- Integrating proteotoxic stress response pathways for induction of cell death in cancer cells: molecular mechanisms and opportunities -- The Hsp70 family of heat shock proteins in tumorigenesis: From molecular mechanisms to therapeutic opportunities -- The ubiquitin-proteasome system (UPS) as a cancer drug target: Emerging mechanisms and therapeutics -- Endoplasmatic reticulum stress in multiple myeloma: From molecular mechanisms to therapeutic opportunities -- Melanomagenic gene alterations viewed from a redox perspective: Molecular mechanisms and therapeutic opportunities -- Targeting hypoxic adaptations of cancer cells: Molecular mechanisms and therapeutic opportunities -- Targeting glycolytic adaptations of cancer cells: from molecular mechanisms to therapeutic opportunities -- At the crossroads between mitochondrial metabolite transport and apoptosis: VDAC1 as an emerging cancer drug target -- Inflammatory dysregulation and cancer: From molecular mechanisms to therapeutic opportunities -- Cell-nonautonomous ER stress-mediated dysregulation of immunity by cancer cells -- Index. |
| Record Nr. | UNINA-9910298284303321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sugar Chains [[electronic resource] ] : Decoding the Functions of Glycans / / edited by Tadashi Suzuki, Kazuaki Ohtsubo, Naoyuki Taniguchi
| Sugar Chains [[electronic resource] ] : Decoding the Functions of Glycans / / edited by Tadashi Suzuki, Kazuaki Ohtsubo, Naoyuki Taniguchi |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Tokyo : , : Springer Japan : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (295 p.) |
| Disciplina |
570
572 614.5999 616079 |
| Soggetto topico |
Biochemistry
Cancer research Immunology Biochemistry, general Cancer Research |
| ISBN | 4-431-55381-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1 N-Glycans and Quality Control of Proteins -- 2 Glycan-Mediated Protein Transport from the Endoplasmic Reticulum -- 3 Gangliosides and T-Cell Immunity -- 4 Gangliosides Regulate Tumor Properties: With Focus on the Suppression of Metastasis-Associated ppGalNAc-T13 with GM1 -- 5 Role of Glycans in Viral Infection -- 6 Discovery and Applications of a Novel Human Pluripotent Stem Cell-Specific Lectin Probe rBC2LCN -- 7 Glycan Structure and Neural Plasticity -- 8 The Involvement of Midkine, a Heparin-Binding Growth Factor, in Cancer Development -- 9 Tumor-Associated Glycans and Their Functional Roles in the Multistep Process of Human Cancer Progression -- 10 Mammalian Sialidase and Tumor Development -- 11 Roles of Glycans in Immune Evasion from NK Immunity -- 12 Glycomic Analysis of Cancer -- 13 Glyco-Predisposing Factor of Diabetes -- 14 Macrophages Govern Ganglioside GM3 Expression in Adipocytes to Regulate Adipogenesis and Insulin Signaling in Homeostatic and Pathogenic Conditions -- 15 O-Mannosyl Glycan and Muscular Dystrophy -- 16 Glycans and Chronic Obstructive Pulmonary Disease (COPD) -- 17 α1,6-Fucosyltransferase Knockout Mice and Schizophrenia-Like Phenotype. . |
| Record Nr. | UNINA-9910298279703321 |
| Tokyo : , : Springer Japan : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeted Therapies for Lung Cancer / / edited by Ravi Salgia
| Targeted Therapies for Lung Cancer / / edited by Ravi Salgia |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (IX, 238 p. 19 illus. in color.) |
| Disciplina |
614.5999
616.9942406 |
| Collana | Current Cancer Research |
| Soggetto topico |
Cancer research
Molecular biology Cancer Research Molecular Medicine |
| ISBN |
9783030178314
9783030178321 (e-book) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. EGFR -- 2. ALK -- 3. ROS1 -- 4. B-RAF -- 5. MET -- 6. HER2 -- 7. NTRK -- 8. SCLC -- 9. Complexities of the Lung Tumor Microenvironment -- 10. KRAS -- 11. Targeting Epigenetic Regulators in Cancer to Overcome Targeted Therapy Resistance. |
| Record Nr. | UNINA-9910337531603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeted Therapy of Acute Myeloid Leukemia / / edited by Michael Andreeff
| Targeted Therapy of Acute Myeloid Leukemia / / edited by Michael Andreeff |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (804 p.) |
| Disciplina |
571.6
579 610 614.5999 |
| Collana | Current Cancer Research |
| Soggetto topico |
Cancer research
Pharmacology Cell biology Microbiology Cancer Research Pharmacology/Toxicology Cell Biology |
| ISBN | 1-4939-1393-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction/Perspective -- Genetics and Classification of Acute Myeloid Leukemia -- Proteomics of AML to guide Selection of Therapy -- Roles of Apoptosis Regulating Bcl-2-Family Genes in AML -- Bcl-2 family: Translational aspects -- IAP Family and Proteins as Therapeutic Targets for Acute Myeloid Leukemia -- TP53 Mutations in Acute Myeloid Leukemia -- Targeting p53 Tumor Suppressor for AML Therapy -- AML-Selective Apoptosis Induction by rationally designed Death Ligand Fusion Protein -- PIM Kinases in AML -- Development of Midostaurin as a Tyrosine Kinase Inhabitor -- FLT3 in AML -- FLT3-ITD. Clinical (Sorafenib/AC220) -- Nucleophosmin (NPM1) -- Raf/MEK Pathway -- The Role of Translational Medicine in Optimization of Therapies targeting the RAS-MAP Kinase Pathway -- Clinical Use of Farnesyltransferase Inhititors -- The P13K-AKT-mTOR signaling Network in AML -- Targeting the P13 Kinase-mTOR Signaling Pathway in AML -- Aurora kinases -- The Clinical Development of Aurora Kinase Inhibitors in Acute Myeloid Leukemia -- AML-Deacetylases -- Methylation in AML-Clinical Applications -- Topic: RARa/RXR Part: Basic -- Arsenic Trioxide in Untreated APL -- Targeting PML-RARα with Retinoids -- NR4A Orphan Receptors as Drug Targets -- Antibody-based Therapeutics Targeting CD33, CD45, and CD66 -- New Heterogeneity of the Leukemic Stem Cells -- Targeting Leukemia Stem Cells -- Regulation of Hematopoiesis by CXCL12/CXCR4 Signaling -- CXC4/CXCL12 as a Therapeutic Target -- VLA-4: A Cell’s Consequential Encounter -- VLA-4 Function and Prognosis in Acute Myeloid Leukemia -- VLA4 in Acute Lymphoblastic Leukemia -- The Leukemic Bone Marrow Microenvironment: Targeting Hypoxia with Hypoxia Activated Pro-Drugs -- Topic: miRs as Therapeutic Targets -- Clinical Implications of MicroRNAs in AML -- Inhibition of Glycolysis as a Therapeutic Strategy in Acute Myeloid Leukemias -- Molecular and Biochemical Basis for the Reprogramming of Intermediary Metabolism in Leukemia Cells -- NK Cell Immunotherapy for AML -- Allogeneic and Autologous T cell Strategies to Enhance Targeting of Acute Myeloid Leukemia -- Indications for Hematopoietic Transplantation for AML -- Mesenchymal Stem/Stromal Cell Targeted Therapies for Solid Tumors and Hematological Malignancies. |
| Record Nr. | UNINA-9910300208003321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease / / edited by Adam Telerman, Robert Amson
| TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease / / edited by Adam Telerman, Robert Amson |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (X, 309 p. 51 illus., 36 illus. in color.) |
| Disciplina | 614.5999 |
| Collana | Results and Problems in Cell Differentiation |
| Soggetto topico |
Cancer
Proteins Stem cells Cytology - Technique Cell death Cancer Biology Stem Cell Biology Cytological Techniques Cell Death |
| ISBN | 3-319-67591-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1 Introduction: How we encountered TCTP and our purpose in studying it -- 2 Structural insights into TCTP and its interactions with ligands and proteins -- 3 Structure-Function relationship of TCTP -- 4 The Translational Controlled Tumour Protein TCTP: Biological Functions and Regulation -- 5 Current understanding of the TCTP interactome -- 6 Role and fate of TCTP in protein degradative pathways -- 7 Roles of the Translationally Controlled Tumor Protein (TCTP) in plant development -- 8 Function of Translationally controlled tumor protein in organ growth: Lessons from Drosophila studies -- 9 Translationally controlled tumor protein (TCTP/HRF) present in animal venoms -- 10 Tctp in Neuronal Circuitry Assembly -- 11 Elusive role of TCTP protein and mRNA in cell cycle and cytoskeleton regulation -- 12 TCTP protein and the cellular response to ionizing radiation-induced DNA damage -- 13 TCTP has a crucial role in the different stages of Prostate Cancer malignant progression -- 14 Role of TCTP for cellular differentiation and cancer therapy -- 15 Targeting TCTP with sertraline and thioridazine in cancer treatment -- 16 . History of Histamine Releasing Factor (HRF)/TCTP including a Potential Therapeutic Target in Asthma and Allergy. |
| Record Nr. | UNINA-9910253933603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Techniques and Methodological Approaches in Breast Cancer Research / / by Jose Russo, Irma H. Russo
| Techniques and Methodological Approaches in Breast Cancer Research / / by Jose Russo, Irma H. Russo |
| Autore | Russo Jose |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (301 p.) |
| Disciplina |
572.6
610 611.01816 614.5999 |
| Soggetto topico |
Cancer research
Molecular biology Proteomics Medicine Gene expression Cancer Research Molecular Medicine Biomedicine, general Gene Expression |
| ISBN | 1-4939-0718-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Laser Capture Microdissection as a Tool for Compartmentalization Studies -- Histological Evaluation of the Normal Breast -- Methodology for Studying the Compartments of the Human Breast -- Methodological approach to Tissue Micro Array for Studying the Normal and Cancerous Human Breast -- In Vitro Techniques for Studying the Normal Breast and the use of Cell Lines in Breast Cancer Research -- In situ Methods for Indentifying the Stem Cell of the Normal and Cancerous Breast -- Imaging Techniques for Evaluation in vitro Behavior of Normal and Cancerous Breast Tissue -- In vivo Studies of Breast Cancer Cells -- RNA Sequencing in the Human Breast -- Methodological Approaches for the Understanding the Epigenetic Landscape of the of the Human Breast and its Implications in Cancer and Prevention. |
| Record Nr. | UNINA-9910298322903321 |
Russo Jose
|
||
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Textbook of Cell Signalling in Cancer : An Educational Approach / / by Jacques Robert
| Textbook of Cell Signalling in Cancer : An Educational Approach / / by Jacques Robert |
| Autore | Robert Jacques |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (341 p.) |
| Disciplina | 614.5999 |
| Soggetto topico |
Oncology
Medicine Pharmacology Cell biology Oncology Biomedicine, general Pharmacology/Toxicology Cell Biology |
| ISBN | 3-319-14340-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Growth Factors and Tyrosine Kinase Receptors -- MAP Kinases Pathway -- Phosphatidylinositol 3-Kinase Pathway -- Cytokine Pathway -- TGFβ Pathway -- G-proteins–coupled Receptors -- Wnt Pathway -- Notch Pathway -- Hedgehog Pathway -- Integrins -- Semaphorins and Adhesion Molecules -- Toll-like Receptors, Interleukin 1 (IL1) and NFκB -- Lymphocyte Receptors Pathways -- Nuclear Receptors Pathways -- Ion Channels–coupled Receptors -- Signalling by Oxygen and Nitric Oxide -- Cell Cycle Control -- Apoptosis Induction and Regulation. |
| Record Nr. | UNINA-9910298283703321 |
|
Robert Jacques
|
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The epidemiology of cancer / edited by Geoffrey J. Bourke
| The epidemiology of cancer / edited by Geoffrey J. Bourke |
| Pubbl/distr/stampa | London : Croom Helm, 1983 |
| Descrizione fisica | 373 p. : ill. ; 23 cm |
| Disciplina | 614.5999 |
| Soggetto non controllato | Cancro |
| ISBN | 0709906706 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-990009186960403321 |
| London : Croom Helm, 1983 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Translational Research in Breast Cancer [[electronic resource] ] : Biomarker Diagnosis, Targeted Therapies and Approaches to Precision Medicine / / edited by Erwei Song, Hai Hu
| Translational Research in Breast Cancer [[electronic resource] ] : Biomarker Diagnosis, Targeted Therapies and Approaches to Precision Medicine / / edited by Erwei Song, Hai Hu |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (VIII, 418 p. 15 illus. in color.) |
| Disciplina | 614.5999 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cancer research
Cell biology Cancer Research Cell Biology |
| ISBN | 981-10-6020-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chap. 1 The Dawning of Translational Breast Cancer: from Bench to Bedside -- Chap. 2 Biomarker Studies in Early Detection and Prognosis of Breast Cancer -- Chap. 3 The Preventive Intervention of Hereditary Breast Cancer -- Chap. 4 Predicting and Overcoming Chemotherapeutic Resistance for Breast Cancer -- Chap. 5 Studies on DNA Damage Repair and Precision Radiotherapy for Breast Cancer -- Chap. 6 Targeted Therapies against Growth Factor Signaling in Breast Cancer -- Chap. 7 Targeting Stemness: Implications for Precision Medicine in Breast Cancer -- Chap. 8 Disrupting Tumor Angiogenesis and “the Hunger Games” for Breast Cancer -- Chap. 9 Key Factors in Breast Cancer Dissemination and Establishment at the Bone: Past, Present and Future Perspectives -- Chap. 10 Perspectives of Reprogramming Breast Cancer Metabolism -- Chap. 11 Metabolic Changes during Cancer Cachexia Pathogenesis -- Chap. 12 Cell Cycle Regulation in Treatment of Breast Cancer -- Chap. 13 BRCA Gene Mutations and Poly (ADP-ribose) Polymerase Inhibitors in Triple-negative Breast Cancer -- Chap. 14 Targeting the Epigenome as a Novel Therapeutic Approach for Breast Cancer -- Chap. 15 Progress in Vaccine Therapies for Breast Cancer -- Chap. 16 Tumor Associated Macrophages as Therapeutic Targets for Breast Cancer -- Chap 17 New Approaches in CAR-T Cell Immunotherapy for Breast Cancer -- Chap 18 Immune Checkpoint Blockade in Breast Cancer Therapy. |
| Record Nr. | UNINA-9910253944203321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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