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Cells, aging, and human disease / / Michael B. Fossel
Cells, aging, and human disease / / Michael B. Fossel
Autore Fossel Michael
Pubbl/distr/stampa Oxford, [England] ; ; New York, New York : , : Oxford University Press, , 2004
Descrizione fisica 1 online resource (504 p.)
Disciplina 612.6/7
Soggetto topico Aging
Cells - Aging
Soggetto genere / forma Electronic books.
ISBN 1-280-48141-2
9780195302540
0-19-803219-6
1-4337-0080-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; 1. The Context; 2. Cell Senescence; 3. Cell Senescence in Aging; 4. The Aging Cascade; 5. Cancer; 6. Parasitic Disease; Part II: The Aging Organism; 7. The Progerias; 8. The Skin; 9. Cardiovascular System; 10. Orthopedic Systems; 11. Hematopoetic and Immune Systems; 12. Endocrine Systems; 13. Nervous System; 14. Kidneys; 15. Muscle; 16. Gastrointestinal System; 17. The Eye; 18. Towards Therapy; References; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W; X; Y; Z
Record Nr. UNINA-9910457980303321
Fossel Michael  
Oxford, [England] ; ; New York, New York : , : Oxford University Press, , 2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Cells, aging, and human disease / / Michael B. Fossel
Cells, aging, and human disease / / Michael B. Fossel
Autore Fossel Michael
Pubbl/distr/stampa Oxford, [England] ; ; New York, New York : , : Oxford University Press, , 2004
Descrizione fisica 1 online resource (504 p.)
Disciplina 612.6/7
Soggetto topico Aging
Cells - Aging
ISBN 0-19-770051-9
1-280-48141-2
9780195302540
0-19-803219-6
1-4337-0080-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; 1. The Context; 2. Cell Senescence; 3. Cell Senescence in Aging; 4. The Aging Cascade; 5. Cancer; 6. Parasitic Disease; Part II: The Aging Organism; 7. The Progerias; 8. The Skin; 9. Cardiovascular System; 10. Orthopedic Systems; 11. Hematopoetic and Immune Systems; 12. Endocrine Systems; 13. Nervous System; 14. Kidneys; 15. Muscle; 16. Gastrointestinal System; 17. The Eye; 18. Towards Therapy; References; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W; X; Y; Z
Record Nr. UNINA-9910784660303321
Fossel Michael  
Oxford, [England] ; ; New York, New York : , : Oxford University Press, , 2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Challenges of biological aging [[electronic resource] /] / Edward J. Masoro
Challenges of biological aging [[electronic resource] /] / Edward J. Masoro
Autore Masoro Edward J
Pubbl/distr/stampa New York, : Springer, c1999
Descrizione fisica 1 online resource (217 p.)
Disciplina 612.6/7
Soggetto topico Aging - Physiological aspects
Aging
Soggetto genere / forma Electronic books.
ISBN 9786611765644
0-8261-0082-1
1-281-76564-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Preface; Acknowledgments; 1 AGING: A BIOLOGICAL PUZZLE; 2 DEMOGRAPHY AND THE SOCIETAL CHALLENGE; 3 WHY AGING OCCURS; 4 HOW AGING OCCURS; 5 BIOLOGICAL BASIS OF AGING: A UNIFYING CONCEPT; 6 THE HUMAN AGING PHENOTYPE; 7 POSSIBLE INTERVENTIONS TO RETARD AGING; Index
Record Nr. UNINA-9910454637003321
Masoro Edward J  
New York, : Springer, c1999
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Challenges of biological aging [[electronic resource] /] / Edward J. Masoro
Challenges of biological aging [[electronic resource] /] / Edward J. Masoro
Autore Masoro Edward J
Pubbl/distr/stampa New York, : Springer, c1999
Descrizione fisica 1 online resource (217 p.)
Disciplina 612.6/7
Soggetto topico Aging - Physiological aspects
Aging
ISBN 9786611765644
0-8261-0082-1
1-281-76564-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Preface; Acknowledgments; 1 AGING: A BIOLOGICAL PUZZLE; 2 DEMOGRAPHY AND THE SOCIETAL CHALLENGE; 3 WHY AGING OCCURS; 4 HOW AGING OCCURS; 5 BIOLOGICAL BASIS OF AGING: A UNIFYING CONCEPT; 6 THE HUMAN AGING PHENOTYPE; 7 POSSIBLE INTERVENTIONS TO RETARD AGING; Index
Record Nr. UNINA-9910782751103321
Masoro Edward J  
New York, : Springer, c1999
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Challenges of biological aging [[electronic resource] /] / Edward J. Masoro
Challenges of biological aging [[electronic resource] /] / Edward J. Masoro
Autore Masoro Edward J
Pubbl/distr/stampa New York, : Springer, c1999
Descrizione fisica 1 online resource (217 p.)
Disciplina 612.6/7
Soggetto topico Aging - Physiological aspects
Aging
ISBN 9786611765644
0-8261-0082-1
1-281-76564-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Preface; Acknowledgments; 1 AGING: A BIOLOGICAL PUZZLE; 2 DEMOGRAPHY AND THE SOCIETAL CHALLENGE; 3 WHY AGING OCCURS; 4 HOW AGING OCCURS; 5 BIOLOGICAL BASIS OF AGING: A UNIFYING CONCEPT; 6 THE HUMAN AGING PHENOTYPE; 7 POSSIBLE INTERVENTIONS TO RETARD AGING; Index
Record Nr. UNINA-9910807198703321
Masoro Edward J  
New York, : Springer, c1999
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Chronic medical disease and cognitive aging [[electronic resource]] : toward a healthy body and brain / / edited by Kristine Yaffe
Chronic medical disease and cognitive aging [[electronic resource]] : toward a healthy body and brain / / edited by Kristine Yaffe
Pubbl/distr/stampa Oxford, England, : Oxford University Press, c2013
Descrizione fisica 1 online resource (317 p.)
Disciplina 612.6/7
Altri autori (Persone) YaffeKristine
Soggetto topico Aging - Physiological aspects
Chronic diseases
Soggetto genere / forma Electronic books.
ISBN 0-19-939622-1
0-19-935315-8
0-19-979366-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Contents; Contributors; Introduction; 1. Epidemiologic Insights Into Blood Pressure and Cognitive Disorders; 2. Cholesterol, Statins, and Late-Life Cognitive Disorders; 3. Cardiovascular Disease and Cognitive Aging; 4. Obesity and Cognitive Health: Implications of an Altered Adiposity Milieu Over the Life-Course; 5. Insulin Resistance and Pathological Brain Aging; 6. Metabolic Syndrome, Other Composite Vascular Risk Scores, and Cognitive Impairment; 7. Chronic Kidney Disease and Cognitive Aging; 8. Sleep Disorders and Cognitive Function in Older Adults
9. Physical Activity and Cognitive Aging10. Dietary Patterns and Dementia; 11. Inflammation and Cognitive Decline; 12. HIV Infection and Aging: An Emerging Chronic Medical Illness; 13. Postoperative Delirium and Cognitive Decline; Disclosures; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; R; S; T; U; V; W; X; Y; Z
Record Nr. UNINA-9910452493603321
Oxford, England, : Oxford University Press, c2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Chronic medical disease and cognitive aging [[electronic resource]] : toward a healthy body and brain / / edited by Kristine Yaffe
Chronic medical disease and cognitive aging [[electronic resource]] : toward a healthy body and brain / / edited by Kristine Yaffe
Pubbl/distr/stampa Oxford, England, : Oxford University Press, c2013
Descrizione fisica 1 online resource (317 p.)
Disciplina 612.6/7
Altri autori (Persone) YaffeKristine
Soggetto topico Aging - Physiological aspects
Chronic diseases
ISBN 0-19-939622-1
0-19-935315-8
0-19-979366-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Contents; Contributors; Introduction; 1. Epidemiologic Insights Into Blood Pressure and Cognitive Disorders; 2. Cholesterol, Statins, and Late-Life Cognitive Disorders; 3. Cardiovascular Disease and Cognitive Aging; 4. Obesity and Cognitive Health: Implications of an Altered Adiposity Milieu Over the Life-Course; 5. Insulin Resistance and Pathological Brain Aging; 6. Metabolic Syndrome, Other Composite Vascular Risk Scores, and Cognitive Impairment; 7. Chronic Kidney Disease and Cognitive Aging; 8. Sleep Disorders and Cognitive Function in Older Adults
9. Physical Activity and Cognitive Aging10. Dietary Patterns and Dementia; 11. Inflammation and Cognitive Decline; 12. HIV Infection and Aging: An Emerging Chronic Medical Illness; 13. Postoperative Delirium and Cognitive Decline; Disclosures; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; R; S; T; U; V; W; X; Y; Z
Record Nr. UNINA-9910779754403321
Oxford, England, : Oxford University Press, c2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Chronic medical disease and cognitive aging [[electronic resource]] : toward a healthy body and brain / / edited by Kristine Yaffe
Chronic medical disease and cognitive aging [[electronic resource]] : toward a healthy body and brain / / edited by Kristine Yaffe
Edizione [1st ed.]
Pubbl/distr/stampa Oxford, England, : Oxford University Press, c2013
Descrizione fisica 1 online resource (317 p.)
Disciplina 612.6/7
Altri autori (Persone) YaffeKristine
Soggetto topico Aging - Physiological aspects
Chronic diseases
ISBN 0-19-939622-1
0-19-935315-8
0-19-979366-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Contents; Contributors; Introduction; 1. Epidemiologic Insights Into Blood Pressure and Cognitive Disorders; 2. Cholesterol, Statins, and Late-Life Cognitive Disorders; 3. Cardiovascular Disease and Cognitive Aging; 4. Obesity and Cognitive Health: Implications of an Altered Adiposity Milieu Over the Life-Course; 5. Insulin Resistance and Pathological Brain Aging; 6. Metabolic Syndrome, Other Composite Vascular Risk Scores, and Cognitive Impairment; 7. Chronic Kidney Disease and Cognitive Aging; 8. Sleep Disorders and Cognitive Function in Older Adults
9. Physical Activity and Cognitive Aging10. Dietary Patterns and Dementia; 11. Inflammation and Cognitive Decline; 12. HIV Infection and Aging: An Emerging Chronic Medical Illness; 13. Postoperative Delirium and Cognitive Decline; Disclosures; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; R; S; T; U; V; W; X; Y; Z
Record Nr. UNINA-9910815088203321
Oxford, England, : Oxford University Press, c2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Handbook of the biology of aging [[electronic resource] /] / editors, Edward J. Masoro and Steven N. Austad
Handbook of the biology of aging [[electronic resource] /] / editors, Edward J. Masoro and Steven N. Austad
Edizione [6th ed.]
Pubbl/distr/stampa Amsterdam ; ; Boston, : Elsevier Academic Press, c2006
Descrizione fisica 1 online resource (681 p.)
Disciplina 612.6/7
Altri autori (Persone) MasoroEdward J
AustadSteven N. <1946->
Collana The handbooks of aging
Soggetto topico Aging - Physiological aspects
Soggetto genere / forma Electronic books.
ISBN 1-280-92693-7
9786610926930
0-08-049140-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Handbook of The Biology of Aging; Copyright Page; Contents; Contributors; Foreword; Preface; About the Editors; Section I. Conceptual and Technical Issues; Chapter 1. Reliability Theory of Aging and Longevity; I. Introduction; II. General Overview of the Reliability Theory Approach; III. Mortality, Failure, and Aging in Biological and Technical Systems; IV. Explanations of Aging Phenomena Using Reliability Theory; V. The Idea of High Initial Damage Load: The HIDL Hypothesis; VI. Reliability Models of Aging for Biological Systems; VII. Evolution of Species Reliability
VIII. ConclusionsReferences; Chapter 2. Are Age-Associated Diseases an Integral Part of Aging?; I. Introduction; II. Concepts of Biological Gerontology; III. Age-Associated Diseases; IV. Primary Aging, Secondary Aging, and "Normal Aging"; V. Evolutionary Theory and Age-Associated Diseases; VI. Analysis of Two Major Age-Associated Disease Processes; VII. Summary and Conclusions; References; Chapter 3. Dietary Restriction, Hormesis, and Small Molecule Mimetics; I. Introduction; II. Key Discoveries; III. Physiological Effects of DR on Mammals; IV. Mechanisms of DR; V. Small-Molecule CR Mimetics
VI. ConclusionsReferences; Chapter 4. Hematopoietic Stem Cells, Aging, and Cancer; I. Stem Cells; II. Stem Cell Aging; III. Stem Cells and Cancer; IV. Conclusions; References; Chapter 5. Mitochondria: A Critical Role in Aging; I. The Mitochondrion; II. Evidence for Increased Oxidative Damage to Mitochondrial Components with Age; III. Mitochondrial Dysfunction and Aging; IV. Mitochondrial Dysfunction and Age-Associated Disease; V. Conclusions; References; Chapter 6. p53 and Mouse Aging Models; I. Introduction to p53; II. p53 and Cellular Senescence
III. Linkage of IGF-1, Sir2, and p53 SignalingIV. Mouse Models of Aging; V. Mouse Models of Accelerated Aging; VI. Mouse Models of Delayed Aging; VII. Links to p53 in Mouse Aging Models; VIII. Mutant Mouse p53 Models, Aging, and Cancer; IX. Influence of p53 on Longevity in Humans; X. How Might p53 Influence Organismal Aging?; References; Chapter 7. Complex Genetic Architecture of Drosophila Longevity; I. Introduction; II. Genome Scan for Quantitative Trait Loci (QTLs); III. Deficiency Complementation Mapping; IV. Complementation Tests to Mutations at Positional Candidate Genes
V. Linkage Disequilibrium (LD) MappingVI. Conclusions and Future Prospects; References; Chapter 8. Evolutionary Biology of Aging: Future Directions; I. Introduction; II. Genetics of Senescence; III. From Physiology to Demography; IV. Parasites and Immune Function; V. Sex, Sexual Selection, and Sexual Conflict; VI. Genetic Variation in Natural Populations; VII. Conclusions; References; Chapter 9. Senescence in Wild Populations of Mammals and Birds; I. Introduction; II. Evidence of Senescence in Wild Populations; III. Patterns of Senescence
IV. Methodological Difficulties in Evaluating Senescence in Wild Populations
Record Nr. UNINA-9910458731603321
Amsterdam ; ; Boston, : Elsevier Academic Press, c2006
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Handbook of the biology of aging [[electronic resource] /] / editors, Edward J. Masoro and Steven N. Austad
Handbook of the biology of aging [[electronic resource] /] / editors, Edward J. Masoro and Steven N. Austad
Edizione [6th ed.]
Pubbl/distr/stampa Amsterdam ; ; Boston, : Elsevier Academic Press, c2006
Descrizione fisica 1 online resource (681 p.)
Disciplina 612.6/7
Altri autori (Persone) MasoroEdward J
AustadSteven N. <1946->
Collana The handbooks of aging
Soggetto topico Aging - Physiological aspects
ISBN 1-280-92693-7
9786610926930
0-08-049140-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Handbook of The Biology of Aging; Copyright Page; Contents; Contributors; Foreword; Preface; About the Editors; Section I. Conceptual and Technical Issues; Chapter 1. Reliability Theory of Aging and Longevity; I. Introduction; II. General Overview of the Reliability Theory Approach; III. Mortality, Failure, and Aging in Biological and Technical Systems; IV. Explanations of Aging Phenomena Using Reliability Theory; V. The Idea of High Initial Damage Load: The HIDL Hypothesis; VI. Reliability Models of Aging for Biological Systems; VII. Evolution of Species Reliability
VIII. ConclusionsReferences; Chapter 2. Are Age-Associated Diseases an Integral Part of Aging?; I. Introduction; II. Concepts of Biological Gerontology; III. Age-Associated Diseases; IV. Primary Aging, Secondary Aging, and "Normal Aging"; V. Evolutionary Theory and Age-Associated Diseases; VI. Analysis of Two Major Age-Associated Disease Processes; VII. Summary and Conclusions; References; Chapter 3. Dietary Restriction, Hormesis, and Small Molecule Mimetics; I. Introduction; II. Key Discoveries; III. Physiological Effects of DR on Mammals; IV. Mechanisms of DR; V. Small-Molecule CR Mimetics
VI. ConclusionsReferences; Chapter 4. Hematopoietic Stem Cells, Aging, and Cancer; I. Stem Cells; II. Stem Cell Aging; III. Stem Cells and Cancer; IV. Conclusions; References; Chapter 5. Mitochondria: A Critical Role in Aging; I. The Mitochondrion; II. Evidence for Increased Oxidative Damage to Mitochondrial Components with Age; III. Mitochondrial Dysfunction and Aging; IV. Mitochondrial Dysfunction and Age-Associated Disease; V. Conclusions; References; Chapter 6. p53 and Mouse Aging Models; I. Introduction to p53; II. p53 and Cellular Senescence
III. Linkage of IGF-1, Sir2, and p53 SignalingIV. Mouse Models of Aging; V. Mouse Models of Accelerated Aging; VI. Mouse Models of Delayed Aging; VII. Links to p53 in Mouse Aging Models; VIII. Mutant Mouse p53 Models, Aging, and Cancer; IX. Influence of p53 on Longevity in Humans; X. How Might p53 Influence Organismal Aging?; References; Chapter 7. Complex Genetic Architecture of Drosophila Longevity; I. Introduction; II. Genome Scan for Quantitative Trait Loci (QTLs); III. Deficiency Complementation Mapping; IV. Complementation Tests to Mutations at Positional Candidate Genes
V. Linkage Disequilibrium (LD) MappingVI. Conclusions and Future Prospects; References; Chapter 8. Evolutionary Biology of Aging: Future Directions; I. Introduction; II. Genetics of Senescence; III. From Physiology to Demography; IV. Parasites and Immune Function; V. Sex, Sexual Selection, and Sexual Conflict; VI. Genetic Variation in Natural Populations; VII. Conclusions; References; Chapter 9. Senescence in Wild Populations of Mammals and Birds; I. Introduction; II. Evidence of Senescence in Wild Populations; III. Patterns of Senescence
IV. Methodological Difficulties in Evaluating Senescence in Wild Populations
Record Nr. UNINA-9910784546503321
Amsterdam ; ; Boston, : Elsevier Academic Press, c2006
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui