Cells, aging, and human disease / / Michael B. Fossel |
Autore | Fossel Michael |
Pubbl/distr/stampa | Oxford, [England] ; ; New York, New York : , : Oxford University Press, , 2004 |
Descrizione fisica | 1 online resource (504 p.) |
Disciplina | 612.6/7 |
Soggetto topico |
Aging
Cells - Aging |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-48141-2
9780195302540 0-19-803219-6 1-4337-0080-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Contents; 1. The Context; 2. Cell Senescence; 3. Cell Senescence in Aging; 4. The Aging Cascade; 5. Cancer; 6. Parasitic Disease; Part II: The Aging Organism; 7. The Progerias; 8. The Skin; 9. Cardiovascular System; 10. Orthopedic Systems; 11. Hematopoetic and Immune Systems; 12. Endocrine Systems; 13. Nervous System; 14. Kidneys; 15. Muscle; 16. Gastrointestinal System; 17. The Eye; 18. Towards Therapy; References; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W; X; Y; Z |
Record Nr. | UNINA-9910457980303321 |
Fossel Michael | ||
Oxford, [England] ; ; New York, New York : , : Oxford University Press, , 2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cells, aging, and human disease / / Michael B. Fossel |
Autore | Fossel Michael |
Pubbl/distr/stampa | Oxford, [England] ; ; New York, New York : , : Oxford University Press, , 2004 |
Descrizione fisica | 1 online resource (504 p.) |
Disciplina | 612.6/7 |
Soggetto topico |
Aging
Cells - Aging |
ISBN |
0-19-770051-9
1-280-48141-2 9780195302540 0-19-803219-6 1-4337-0080-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Contents; 1. The Context; 2. Cell Senescence; 3. Cell Senescence in Aging; 4. The Aging Cascade; 5. Cancer; 6. Parasitic Disease; Part II: The Aging Organism; 7. The Progerias; 8. The Skin; 9. Cardiovascular System; 10. Orthopedic Systems; 11. Hematopoetic and Immune Systems; 12. Endocrine Systems; 13. Nervous System; 14. Kidneys; 15. Muscle; 16. Gastrointestinal System; 17. The Eye; 18. Towards Therapy; References; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W; X; Y; Z |
Record Nr. | UNINA-9910784660303321 |
Fossel Michael | ||
Oxford, [England] ; ; New York, New York : , : Oxford University Press, , 2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Challenges of biological aging [[electronic resource] /] / Edward J. Masoro |
Autore | Masoro Edward J |
Pubbl/distr/stampa | New York, : Springer, c1999 |
Descrizione fisica | 1 online resource (217 p.) |
Disciplina | 612.6/7 |
Soggetto topico |
Aging - Physiological aspects
Aging |
Soggetto genere / forma | Electronic books. |
ISBN |
9786611765644
0-8261-0082-1 1-281-76564-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Contents; Preface; Acknowledgments; 1 AGING: A BIOLOGICAL PUZZLE; 2 DEMOGRAPHY AND THE SOCIETAL CHALLENGE; 3 WHY AGING OCCURS; 4 HOW AGING OCCURS; 5 BIOLOGICAL BASIS OF AGING: A UNIFYING CONCEPT; 6 THE HUMAN AGING PHENOTYPE; 7 POSSIBLE INTERVENTIONS TO RETARD AGING; Index |
Record Nr. | UNINA-9910454637003321 |
Masoro Edward J | ||
New York, : Springer, c1999 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Challenges of biological aging [[electronic resource] /] / Edward J. Masoro |
Autore | Masoro Edward J |
Pubbl/distr/stampa | New York, : Springer, c1999 |
Descrizione fisica | 1 online resource (217 p.) |
Disciplina | 612.6/7 |
Soggetto topico |
Aging - Physiological aspects
Aging |
ISBN |
9786611765644
0-8261-0082-1 1-281-76564-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Contents; Preface; Acknowledgments; 1 AGING: A BIOLOGICAL PUZZLE; 2 DEMOGRAPHY AND THE SOCIETAL CHALLENGE; 3 WHY AGING OCCURS; 4 HOW AGING OCCURS; 5 BIOLOGICAL BASIS OF AGING: A UNIFYING CONCEPT; 6 THE HUMAN AGING PHENOTYPE; 7 POSSIBLE INTERVENTIONS TO RETARD AGING; Index |
Record Nr. | UNINA-9910782751103321 |
Masoro Edward J | ||
New York, : Springer, c1999 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Challenges of biological aging [[electronic resource] /] / Edward J. Masoro |
Autore | Masoro Edward J |
Pubbl/distr/stampa | New York, : Springer, c1999 |
Descrizione fisica | 1 online resource (217 p.) |
Disciplina | 612.6/7 |
Soggetto topico |
Aging - Physiological aspects
Aging |
ISBN |
9786611765644
0-8261-0082-1 1-281-76564-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Contents; Preface; Acknowledgments; 1 AGING: A BIOLOGICAL PUZZLE; 2 DEMOGRAPHY AND THE SOCIETAL CHALLENGE; 3 WHY AGING OCCURS; 4 HOW AGING OCCURS; 5 BIOLOGICAL BASIS OF AGING: A UNIFYING CONCEPT; 6 THE HUMAN AGING PHENOTYPE; 7 POSSIBLE INTERVENTIONS TO RETARD AGING; Index |
Record Nr. | UNINA-9910807198703321 |
Masoro Edward J | ||
New York, : Springer, c1999 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Chronic medical disease and cognitive aging [[electronic resource]] : toward a healthy body and brain / / edited by Kristine Yaffe |
Pubbl/distr/stampa | Oxford, England, : Oxford University Press, c2013 |
Descrizione fisica | 1 online resource (317 p.) |
Disciplina | 612.6/7 |
Altri autori (Persone) | YaffeKristine |
Soggetto topico |
Aging - Physiological aspects
Chronic diseases |
Soggetto genere / forma | Electronic books. |
ISBN |
0-19-939622-1
0-19-935315-8 0-19-979366-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Contents; Contributors; Introduction; 1. Epidemiologic Insights Into Blood Pressure and Cognitive Disorders; 2. Cholesterol, Statins, and Late-Life Cognitive Disorders; 3. Cardiovascular Disease and Cognitive Aging; 4. Obesity and Cognitive Health: Implications of an Altered Adiposity Milieu Over the Life-Course; 5. Insulin Resistance and Pathological Brain Aging; 6. Metabolic Syndrome, Other Composite Vascular Risk Scores, and Cognitive Impairment; 7. Chronic Kidney Disease and Cognitive Aging; 8. Sleep Disorders and Cognitive Function in Older Adults
9. Physical Activity and Cognitive Aging10. Dietary Patterns and Dementia; 11. Inflammation and Cognitive Decline; 12. HIV Infection and Aging: An Emerging Chronic Medical Illness; 13. Postoperative Delirium and Cognitive Decline; Disclosures; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; R; S; T; U; V; W; X; Y; Z |
Record Nr. | UNINA-9910452493603321 |
Oxford, England, : Oxford University Press, c2013 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Chronic medical disease and cognitive aging [[electronic resource]] : toward a healthy body and brain / / edited by Kristine Yaffe |
Pubbl/distr/stampa | Oxford, England, : Oxford University Press, c2013 |
Descrizione fisica | 1 online resource (317 p.) |
Disciplina | 612.6/7 |
Altri autori (Persone) | YaffeKristine |
Soggetto topico |
Aging - Physiological aspects
Chronic diseases |
ISBN |
0-19-939622-1
0-19-935315-8 0-19-979366-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Contents; Contributors; Introduction; 1. Epidemiologic Insights Into Blood Pressure and Cognitive Disorders; 2. Cholesterol, Statins, and Late-Life Cognitive Disorders; 3. Cardiovascular Disease and Cognitive Aging; 4. Obesity and Cognitive Health: Implications of an Altered Adiposity Milieu Over the Life-Course; 5. Insulin Resistance and Pathological Brain Aging; 6. Metabolic Syndrome, Other Composite Vascular Risk Scores, and Cognitive Impairment; 7. Chronic Kidney Disease and Cognitive Aging; 8. Sleep Disorders and Cognitive Function in Older Adults
9. Physical Activity and Cognitive Aging10. Dietary Patterns and Dementia; 11. Inflammation and Cognitive Decline; 12. HIV Infection and Aging: An Emerging Chronic Medical Illness; 13. Postoperative Delirium and Cognitive Decline; Disclosures; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; R; S; T; U; V; W; X; Y; Z |
Record Nr. | UNINA-9910779754403321 |
Oxford, England, : Oxford University Press, c2013 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Chronic medical disease and cognitive aging [[electronic resource]] : toward a healthy body and brain / / edited by Kristine Yaffe |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Oxford, England, : Oxford University Press, c2013 |
Descrizione fisica | 1 online resource (317 p.) |
Disciplina | 612.6/7 |
Altri autori (Persone) | YaffeKristine |
Soggetto topico |
Aging - Physiological aspects
Chronic diseases |
ISBN |
0-19-939622-1
0-19-935315-8 0-19-979366-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Contents; Contributors; Introduction; 1. Epidemiologic Insights Into Blood Pressure and Cognitive Disorders; 2. Cholesterol, Statins, and Late-Life Cognitive Disorders; 3. Cardiovascular Disease and Cognitive Aging; 4. Obesity and Cognitive Health: Implications of an Altered Adiposity Milieu Over the Life-Course; 5. Insulin Resistance and Pathological Brain Aging; 6. Metabolic Syndrome, Other Composite Vascular Risk Scores, and Cognitive Impairment; 7. Chronic Kidney Disease and Cognitive Aging; 8. Sleep Disorders and Cognitive Function in Older Adults
9. Physical Activity and Cognitive Aging10. Dietary Patterns and Dementia; 11. Inflammation and Cognitive Decline; 12. HIV Infection and Aging: An Emerging Chronic Medical Illness; 13. Postoperative Delirium and Cognitive Decline; Disclosures; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; R; S; T; U; V; W; X; Y; Z |
Record Nr. | UNINA-9910815088203321 |
Oxford, England, : Oxford University Press, c2013 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Handbook of the biology of aging [[electronic resource] /] / editors, Edward J. Masoro and Steven N. Austad |
Edizione | [6th ed.] |
Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier Academic Press, c2006 |
Descrizione fisica | 1 online resource (681 p.) |
Disciplina | 612.6/7 |
Altri autori (Persone) |
MasoroEdward J
AustadSteven N. <1946-> |
Collana | The handbooks of aging |
Soggetto topico | Aging - Physiological aspects |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-92693-7
9786610926930 0-08-049140-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Handbook of The Biology of Aging; Copyright Page; Contents; Contributors; Foreword; Preface; About the Editors; Section I. Conceptual and Technical Issues; Chapter 1. Reliability Theory of Aging and Longevity; I. Introduction; II. General Overview of the Reliability Theory Approach; III. Mortality, Failure, and Aging in Biological and Technical Systems; IV. Explanations of Aging Phenomena Using Reliability Theory; V. The Idea of High Initial Damage Load: The HIDL Hypothesis; VI. Reliability Models of Aging for Biological Systems; VII. Evolution of Species Reliability
VIII. ConclusionsReferences; Chapter 2. Are Age-Associated Diseases an Integral Part of Aging?; I. Introduction; II. Concepts of Biological Gerontology; III. Age-Associated Diseases; IV. Primary Aging, Secondary Aging, and "Normal Aging"; V. Evolutionary Theory and Age-Associated Diseases; VI. Analysis of Two Major Age-Associated Disease Processes; VII. Summary and Conclusions; References; Chapter 3. Dietary Restriction, Hormesis, and Small Molecule Mimetics; I. Introduction; II. Key Discoveries; III. Physiological Effects of DR on Mammals; IV. Mechanisms of DR; V. Small-Molecule CR Mimetics VI. ConclusionsReferences; Chapter 4. Hematopoietic Stem Cells, Aging, and Cancer; I. Stem Cells; II. Stem Cell Aging; III. Stem Cells and Cancer; IV. Conclusions; References; Chapter 5. Mitochondria: A Critical Role in Aging; I. The Mitochondrion; II. Evidence for Increased Oxidative Damage to Mitochondrial Components with Age; III. Mitochondrial Dysfunction and Aging; IV. Mitochondrial Dysfunction and Age-Associated Disease; V. Conclusions; References; Chapter 6. p53 and Mouse Aging Models; I. Introduction to p53; II. p53 and Cellular Senescence III. Linkage of IGF-1, Sir2, and p53 SignalingIV. Mouse Models of Aging; V. Mouse Models of Accelerated Aging; VI. Mouse Models of Delayed Aging; VII. Links to p53 in Mouse Aging Models; VIII. Mutant Mouse p53 Models, Aging, and Cancer; IX. Influence of p53 on Longevity in Humans; X. How Might p53 Influence Organismal Aging?; References; Chapter 7. Complex Genetic Architecture of Drosophila Longevity; I. Introduction; II. Genome Scan for Quantitative Trait Loci (QTLs); III. Deficiency Complementation Mapping; IV. Complementation Tests to Mutations at Positional Candidate Genes V. Linkage Disequilibrium (LD) MappingVI. Conclusions and Future Prospects; References; Chapter 8. Evolutionary Biology of Aging: Future Directions; I. Introduction; II. Genetics of Senescence; III. From Physiology to Demography; IV. Parasites and Immune Function; V. Sex, Sexual Selection, and Sexual Conflict; VI. Genetic Variation in Natural Populations; VII. Conclusions; References; Chapter 9. Senescence in Wild Populations of Mammals and Birds; I. Introduction; II. Evidence of Senescence in Wild Populations; III. Patterns of Senescence IV. Methodological Difficulties in Evaluating Senescence in Wild Populations |
Record Nr. | UNINA-9910458731603321 |
Amsterdam ; ; Boston, : Elsevier Academic Press, c2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Handbook of the biology of aging [[electronic resource] /] / editors, Edward J. Masoro and Steven N. Austad |
Edizione | [6th ed.] |
Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier Academic Press, c2006 |
Descrizione fisica | 1 online resource (681 p.) |
Disciplina | 612.6/7 |
Altri autori (Persone) |
MasoroEdward J
AustadSteven N. <1946-> |
Collana | The handbooks of aging |
Soggetto topico | Aging - Physiological aspects |
ISBN |
1-280-92693-7
9786610926930 0-08-049140-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Handbook of The Biology of Aging; Copyright Page; Contents; Contributors; Foreword; Preface; About the Editors; Section I. Conceptual and Technical Issues; Chapter 1. Reliability Theory of Aging and Longevity; I. Introduction; II. General Overview of the Reliability Theory Approach; III. Mortality, Failure, and Aging in Biological and Technical Systems; IV. Explanations of Aging Phenomena Using Reliability Theory; V. The Idea of High Initial Damage Load: The HIDL Hypothesis; VI. Reliability Models of Aging for Biological Systems; VII. Evolution of Species Reliability
VIII. ConclusionsReferences; Chapter 2. Are Age-Associated Diseases an Integral Part of Aging?; I. Introduction; II. Concepts of Biological Gerontology; III. Age-Associated Diseases; IV. Primary Aging, Secondary Aging, and "Normal Aging"; V. Evolutionary Theory and Age-Associated Diseases; VI. Analysis of Two Major Age-Associated Disease Processes; VII. Summary and Conclusions; References; Chapter 3. Dietary Restriction, Hormesis, and Small Molecule Mimetics; I. Introduction; II. Key Discoveries; III. Physiological Effects of DR on Mammals; IV. Mechanisms of DR; V. Small-Molecule CR Mimetics VI. ConclusionsReferences; Chapter 4. Hematopoietic Stem Cells, Aging, and Cancer; I. Stem Cells; II. Stem Cell Aging; III. Stem Cells and Cancer; IV. Conclusions; References; Chapter 5. Mitochondria: A Critical Role in Aging; I. The Mitochondrion; II. Evidence for Increased Oxidative Damage to Mitochondrial Components with Age; III. Mitochondrial Dysfunction and Aging; IV. Mitochondrial Dysfunction and Age-Associated Disease; V. Conclusions; References; Chapter 6. p53 and Mouse Aging Models; I. Introduction to p53; II. p53 and Cellular Senescence III. Linkage of IGF-1, Sir2, and p53 SignalingIV. Mouse Models of Aging; V. Mouse Models of Accelerated Aging; VI. Mouse Models of Delayed Aging; VII. Links to p53 in Mouse Aging Models; VIII. Mutant Mouse p53 Models, Aging, and Cancer; IX. Influence of p53 on Longevity in Humans; X. How Might p53 Influence Organismal Aging?; References; Chapter 7. Complex Genetic Architecture of Drosophila Longevity; I. Introduction; II. Genome Scan for Quantitative Trait Loci (QTLs); III. Deficiency Complementation Mapping; IV. Complementation Tests to Mutations at Positional Candidate Genes V. Linkage Disequilibrium (LD) MappingVI. Conclusions and Future Prospects; References; Chapter 8. Evolutionary Biology of Aging: Future Directions; I. Introduction; II. Genetics of Senescence; III. From Physiology to Demography; IV. Parasites and Immune Function; V. Sex, Sexual Selection, and Sexual Conflict; VI. Genetic Variation in Natural Populations; VII. Conclusions; References; Chapter 9. Senescence in Wild Populations of Mammals and Birds; I. Introduction; II. Evidence of Senescence in Wild Populations; III. Patterns of Senescence IV. Methodological Difficulties in Evaluating Senescence in Wild Populations |
Record Nr. | UNINA-9910784546503321 |
Amsterdam ; ; Boston, : Elsevier Academic Press, c2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|