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Molekularni genetika pro bioanalytiky / / Martin Beranek
| Molekularni genetika pro bioanalytiky / / Martin Beranek |
| Autore | Beranek Martin |
| Edizione | [1. vydani.] |
| Pubbl/distr/stampa | Praha, [Czech Republic] : , : Nakladatelstvi Karolinum, , 2016 |
| Descrizione fisica | 1 online resource (194 p.) |
| Disciplina | 574.87328 |
| Collana | Ucebni Texty Univerzity Karlovy V Praze |
| Soggetto topico | Molecular genetics |
| Soggetto genere / forma | Electronic books. |
| ISBN | 80-246-3246-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | cze |
| Nota di contenuto | 8.6 Klinický význam molekulárního klonování |
| Record Nr. | UNINA-9910465276603321 |
Beranek Martin
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| Praha, [Czech Republic] : , : Nakladatelstvi Karolinum, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molekularni genetika pro bioanalytiky / / Martin Beranek
| Molekularni genetika pro bioanalytiky / / Martin Beranek |
| Autore | Beranek Martin |
| Edizione | [1. vydani.] |
| Pubbl/distr/stampa | Praha, [Czech Republic] : , : Nakladatelstvi Karolinum, , 2016 |
| Descrizione fisica | 1 online resource (194 p.) |
| Disciplina | 574.87328 |
| Collana | Ucebni Texty Univerzity Karlovy V Praze |
| Soggetto topico | Molecular genetics |
| ISBN | 80-246-3246-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | cze |
| Nota di contenuto | 8.6 Klinický význam molekulárního klonování |
| Record Nr. | UNINA-9910798370803321 |
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Beranek Martin
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| Praha, [Czech Republic] : , : Nakladatelstvi Karolinum, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molekularni genetika pro bioanalytiky / / Martin Beranek
| Molekularni genetika pro bioanalytiky / / Martin Beranek |
| Autore | Beranek Martin |
| Edizione | [1. vydani.] |
| Pubbl/distr/stampa | Praha, [Czech Republic] : , : Nakladatelstvi Karolinum, , 2016 |
| Descrizione fisica | 1 online resource (194 p.) |
| Disciplina | 574.87328 |
| Collana | Ucebni Texty Univerzity Karlovy V Praze |
| Soggetto topico | Molecular genetics |
| ISBN | 80-246-3246-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | cze |
| Nota di contenuto | 8.6 Klinický význam molekulárního klonování |
| Record Nr. | UNINA-9910821921903321 |
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Beranek Martin
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| Praha, [Czech Republic] : , : Nakladatelstvi Karolinum, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Non-canonical Cyclic Nucleotides / / edited by Roland Seifert
| Non-canonical Cyclic Nucleotides / / edited by Roland Seifert |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (VIII, 387 p. 65 illus., 35 illus. in color.) |
| Disciplina | 574.87328 |
| Collana | Handbook of Experimental Pharmacology |
| Soggetto topico |
Pharmacology
Biochemistry Human physiology Pharmacology/Toxicology Biochemistry, general Human Physiology |
| ISBN | 3-319-52673-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I: 3’,5’-cCMP and 3’,5’-cUMP as second messengers: cCMP and cUMP across the tree of life: From cCMP and cUMP generators to cCMP- and cUMP-regulated cell functions -- cCMP and cUMP in apoptosis: Concepts and methods -- Mammalian nucleotidyl cyclases and their nucleotide binding sites -- The Pseudomonas aeruginosa exoenzyme Y: A promiscuous nucleotidyl cyclase edema factor and virulence determinant -- Cyclic nucleotide monophosphates in plants and plant signalling -- cAMP-dependent protein kinase and cGMP-dependent protein kinase as cyclic nucleotide effectors -- Regulation of HCN ion channels by non-canonical cyclic nucleotides -- Identification of cCMP and cUMP substrate proteins and cross-talk between cNMPs -- Inactivation of non-canonical cyclic nucleotides: Hydrolysis and transport -- Part II: 3’,5’-cIMP, 8-nitro-cGMP, 2’,3’-cNMPs and cyclic dinucleotides as signaling molecules: 3’,5’-cIMP as potential second messenger in the vascular wall -- The discovery of 2’,3’-cNMPs in mammalian systems: From rodents to humans -- 8-Nitro-cGMP: A novel protein-reactive cNMP and its emerging roles in autophagy -- Cyclic dinucleotides in the scope of the mammalian immune system -- Part III: Methods/Tools for cNMP research: Mass-spectrometric analysis of non-canonical cyclic nucleotides -- Medicinal chemistry of the noncanonical cyclic nucleotides cCMP and cUMP -- Holistic methods for the analysis of cNMP effects -- The chemistry of the non-canonical cyclic dinucleotide 2'3'-cGAMP and its analogs. |
| Record Nr. | UNINA-9910253928803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nucleic acid biochemistry and molecular biology / W. I. P. Mainwaring, J. H. Parish et J. D. Pickering, N. H. Mann
| Nucleic acid biochemistry and molecular biology / W. I. P. Mainwaring, J. H. Parish et J. D. Pickering, N. H. Mann |
| Autore | Mainwaring, W. Ian P. |
| Pubbl/distr/stampa | Oxford ; London ; Edinburgh, : Blackwell scientific publications, c1982 |
| Descrizione fisica | XI, 557 p. : ill. ; 25 cm. |
| Disciplina | 574.87328 |
| Soggetto non controllato | Biologia molecolare |
| ISBN | 0632006323 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910773791103321 |
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Mainwaring, W. Ian P.
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| Oxford ; London ; Edinburgh, : Blackwell scientific publications, c1982 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nucleic acids as molecular diagnostics / / edited by Andreas Keller and Eckart Meese
| Nucleic acids as molecular diagnostics / / edited by Andreas Keller and Eckart Meese |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH, , 2015 |
| Descrizione fisica | 1 online resource (393 p.) |
| Disciplina | 574.87328 |
| Soggetto topico |
Nucleic acids
Molecular diagnosis |
| ISBN |
3-527-67222-2
3-527-67216-8 3-527-67223-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Nucleic Acids as Molecular Diagnostics; Contents; List of Contributors; Preface; 1 Next-Generation Sequencing for Clinical Diagnostics of Cardiomyopathies; 1.1 Introduction; 1.2 Cardiomyopathies and Why Genetic Testing is Needed; 1.3 NGS; 1.4 NGS for Cardiomyopathies; 1.5 Sample Preparation; 1.6 Bioinformatics Analysis Pipeline; 1.7 Interpretation of Results and Translation into Clinical Practice; References; 2 MicroRNAs as Novel Biomarkers in Cardiovascular Medicine; 2.1 Introduction; 2.2 miRNAs are Associated with Cardiovascular Risk Factors; 2.3 miRNAs in Coronary Artery Disease
2.4 miRNAs in Cardiac Ischemia and Necrosis2.5 miRNAs as Biomarkers of Heart Failure; 2.6 Future Challenges; Acknowledgments; References; 3 MicroRNAs in Primary Brain Tumors: Functional Impact and Potential Use for Diagnostic Purposes; 3.1 Background; 3.2 Gliomas; 3.2.1 miRNA as Biomarkers in Glioma Tissue; 3.2.2 Circulating miRNA as Biomarkers; 3.3 Meningiomas; 3.4 Pituitary Adenomas; 3.5 Medulloblastomas; 3.6 Other Brain Tumors; 3.6.1 Schwannomas; 3.6.2 PCNSLs; 3.7 Summary and Outlook; References; 4 Genetic and Epigenetic Alterations in Sporadic Colorectal Cancer: Clinical Implications 4.1 Introduction4.2 Chromosomal Instability; 4.3 Microsatellite Instability; 4.4 Driver Somatic Mutations in CRC; 4.4.1 APC; 4.4.2 TP53; 4.4.3 KRAS; 4.4.4 BRAF; 4.4.5 PIK3CA; 4.4.6 Other Mutations; 4.5 Epigenetic Instability in CRC; 4.6 Hypomethylation; 4.7 CpG Island Methylator Phenotype; 4.8 Concluding Remarks; References; 5 Nucleic Acid-Based Markers in Urologic Malignancies; 5.1 Introduction; 5.2 Bladder Cancer; 5.2.1 Hereditary Factors for Bladder Cancer; 5.2.2 Single Nucleotide Polymorphisms; 5.2.3 RNA Alterations in Bladder Cancer; 5.2.3.1 FGFR3 Pathway; 5.2.3.2 p53 Pathway 5.2.3.3 Urine-Based Markers5.2.3.4 Serum-Based Markers; 5.2.4 Sporadic Factors for Bladder Cancer; 5.2.5 Genetic Changes in Non-Invasive Papillary Urothelial Carcinoma; 5.2.5.1 FGFR 3; 5.2.5.2 Changes in the Phosphatidylinositol 3-Kinase Pathway; 5.2.6 Genetic Changes in Muscle-Invasive Urothelial Carcinoma; 5.2.6.1 TP53, RB, and Cell Cycle Control Genes; 5.2.6.2 Other Genomic Alterations; 5.2.7 Genetic Alterations with Unrecognized Associations to Tumor Stage and Grade; 5.2.7.1 Alterations of Chromosome 9; 5.2.7.2 RAS Gene Mutations; 5.3 Prostate Cancer 5.3.1 Hereditary Factors for Prostate Cancer5.3.2 Sporadic Factors for Prostate Cancer; 5.3.2.1 PSA and Other Protein Markers; 5.3.2.2 Nucleic Acid Biomarkers; 5.3.3 Prostate Cancer: Summary; 5.4 Renal Cell Carcinoma; 5.4.1 Hereditary Factors for RCC; 5.4.2 Sporadic Factors for RCC; 5.4.2.1 The Old; 5.4.2.2 The New; 5.5 Summary; References; 6 From the Genetic Make-Up to the Molecular Signature of Non-Coding RNA in Breast Cancer; 6.1 Introduction; 6.2 Molecular Breast Cancer Detection; 6.2.1 Circulating Free DNA; 6.2.2 Long Intergenic Non-Coding RNA; 6.2.2.1 HOTAIR; 6.2.2.2 H19; 6.2.2.3 GAS5 6.2.2.4 LSINCT5 |
| Record Nr. | UNINA-9910132173003321 |
| Weinheim, Germany : , : Wiley-VCH, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nucleic acids as molecular diagnostics / / edited by Andreas Keller and Eckart Meese
| Nucleic acids as molecular diagnostics / / edited by Andreas Keller and Eckart Meese |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH, , 2015 |
| Descrizione fisica | 1 online resource (393 p.) |
| Disciplina | 574.87328 |
| Soggetto topico |
Nucleic acids
Molecular diagnosis |
| ISBN |
3-527-67222-2
3-527-67216-8 3-527-67223-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Nucleic Acids as Molecular Diagnostics; Contents; List of Contributors; Preface; 1 Next-Generation Sequencing for Clinical Diagnostics of Cardiomyopathies; 1.1 Introduction; 1.2 Cardiomyopathies and Why Genetic Testing is Needed; 1.3 NGS; 1.4 NGS for Cardiomyopathies; 1.5 Sample Preparation; 1.6 Bioinformatics Analysis Pipeline; 1.7 Interpretation of Results and Translation into Clinical Practice; References; 2 MicroRNAs as Novel Biomarkers in Cardiovascular Medicine; 2.1 Introduction; 2.2 miRNAs are Associated with Cardiovascular Risk Factors; 2.3 miRNAs in Coronary Artery Disease
2.4 miRNAs in Cardiac Ischemia and Necrosis2.5 miRNAs as Biomarkers of Heart Failure; 2.6 Future Challenges; Acknowledgments; References; 3 MicroRNAs in Primary Brain Tumors: Functional Impact and Potential Use for Diagnostic Purposes; 3.1 Background; 3.2 Gliomas; 3.2.1 miRNA as Biomarkers in Glioma Tissue; 3.2.2 Circulating miRNA as Biomarkers; 3.3 Meningiomas; 3.4 Pituitary Adenomas; 3.5 Medulloblastomas; 3.6 Other Brain Tumors; 3.6.1 Schwannomas; 3.6.2 PCNSLs; 3.7 Summary and Outlook; References; 4 Genetic and Epigenetic Alterations in Sporadic Colorectal Cancer: Clinical Implications 4.1 Introduction4.2 Chromosomal Instability; 4.3 Microsatellite Instability; 4.4 Driver Somatic Mutations in CRC; 4.4.1 APC; 4.4.2 TP53; 4.4.3 KRAS; 4.4.4 BRAF; 4.4.5 PIK3CA; 4.4.6 Other Mutations; 4.5 Epigenetic Instability in CRC; 4.6 Hypomethylation; 4.7 CpG Island Methylator Phenotype; 4.8 Concluding Remarks; References; 5 Nucleic Acid-Based Markers in Urologic Malignancies; 5.1 Introduction; 5.2 Bladder Cancer; 5.2.1 Hereditary Factors for Bladder Cancer; 5.2.2 Single Nucleotide Polymorphisms; 5.2.3 RNA Alterations in Bladder Cancer; 5.2.3.1 FGFR3 Pathway; 5.2.3.2 p53 Pathway 5.2.3.3 Urine-Based Markers5.2.3.4 Serum-Based Markers; 5.2.4 Sporadic Factors for Bladder Cancer; 5.2.5 Genetic Changes in Non-Invasive Papillary Urothelial Carcinoma; 5.2.5.1 FGFR 3; 5.2.5.2 Changes in the Phosphatidylinositol 3-Kinase Pathway; 5.2.6 Genetic Changes in Muscle-Invasive Urothelial Carcinoma; 5.2.6.1 TP53, RB, and Cell Cycle Control Genes; 5.2.6.2 Other Genomic Alterations; 5.2.7 Genetic Alterations with Unrecognized Associations to Tumor Stage and Grade; 5.2.7.1 Alterations of Chromosome 9; 5.2.7.2 RAS Gene Mutations; 5.3 Prostate Cancer 5.3.1 Hereditary Factors for Prostate Cancer5.3.2 Sporadic Factors for Prostate Cancer; 5.3.2.1 PSA and Other Protein Markers; 5.3.2.2 Nucleic Acid Biomarkers; 5.3.3 Prostate Cancer: Summary; 5.4 Renal Cell Carcinoma; 5.4.1 Hereditary Factors for RCC; 5.4.2 Sporadic Factors for RCC; 5.4.2.1 The Old; 5.4.2.2 The New; 5.5 Summary; References; 6 From the Genetic Make-Up to the Molecular Signature of Non-Coding RNA in Breast Cancer; 6.1 Introduction; 6.2 Molecular Breast Cancer Detection; 6.2.1 Circulating Free DNA; 6.2.2 Long Intergenic Non-Coding RNA; 6.2.2.1 HOTAIR; 6.2.2.2 H19; 6.2.2.3 GAS5 6.2.2.4 LSINCT5 |
| Record Nr. | UNINA-9910821196703321 |
| Weinheim, Germany : , : Wiley-VCH, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nucleic acids sequencing : a practical approach / edited by C. J. Howe ; E . S. Ward
| Nucleic acids sequencing : a practical approach / edited by C. J. Howe ; E . S. Ward |
| Pubbl/distr/stampa |
Oxford |
| Descrizione fisica | XIII, 241 p. ; 23 cm |
| Disciplina | 574.87328 |
| Altri autori (Persone) |
Ward, Elizabeth Stuart
Howe, Cynthia J. |
| Collana | The practical approach series |
| Soggetto non controllato | Acidi nucleici |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910763895103321 |
| Oxford <etc.>, : IRL press, 1989 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Photoinduced Phenomena in Nucleic Acids I : Nucleobases in the Gas Phase and in Solvents / / edited by Mario Barbatti, Antonio Carlos Borin, Susanne Ullrich
| Photoinduced Phenomena in Nucleic Acids I : Nucleobases in the Gas Phase and in Solvents / / edited by Mario Barbatti, Antonio Carlos Borin, Susanne Ullrich |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (VII, 362 p. 118 illus., 84 illus. in color.) |
| Disciplina | 574.87328 |
| Collana | Topics in Current Chemistry |
| Soggetto topico | Biotechnology |
| ISBN | 3-319-13371-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- Photoinduced Processes in Nucleic Acids -- 1 Introduction -- 2 Historical Background -- 3 Absorption and Emission -- 4 Photodynamics -- 4.1 Monomers -- 4.1.1 Purine Bases -- 4.1.2 Pyrimidine Bases -- 4.1.3 Modified Bases -- Thio-analogues -- Aza-analogues -- 4.2 Base Pairs -- 4.3 Stacking, DNA Fragments -- 4.3.1 Photoinduced Pyrimidine Dimers -- 5 Open Problems and Debates in the Field -- 5.1 Deactivation of Adenine: Multiple Pictures -- 5.2 Cytosine: Tautomers, Triple Intersections, and Triplet States -- 5.3 Why Does Thymine Have the Longest Lifetime? -- 5.4 Dynamics Simulation Cacophony -- 5.5 UVA or UVB: Which Is Most Dangerous? -- 5.6 Does Ultrafast Deactivation Matter for Photostability? -- Conclusions -- References -- UV-Excitation from an Experimental Perspective: Frequency Resolved -- 1 Introduction -- 2 Vibronic Spectra -- 2.1 Spectroscopic Techniques -- 3 Isomers -- 4 Derivatives -- 5 Character of the Excited State -- 6 Tautomers -- 7 Intermolecular Effects: Clusters -- 8 Summary -- References -- Excitation of Nucleobases from a Computational Perspective I: Reaction Paths -- 1 Introduction -- 2 Computational Strategies in Photochemistry -- 2.1 Photochemical Reaction Paths -- 2.2 Quantum-Chemical Methods -- 3 Non-Adiabatic Photochemistry of Pyrimidines -- 3.1 Photochemical Reaction Paths for Thymine -- 3.2 Photochemical Reaction Paths for Cytosine -- 3.3 Photochemical Reaction Paths for Uracil -- 4 Non-Adiabatic Photochemistry of Purines -- 4.1 Photochemical Reaction Paths for Adenine -- 4.2 Photochemical Reaction Paths for Guanine -- 5 Final Remarks and Future Perspective -- References -- Excitation of Nucleobases from a Computational Perspective II: Dynamics -- 1 Introduction -- 2 Computational Approaches for Nuclear Dynamics -- 2.1 The Schrödinger Equation and the Born-Oppenheimer Approximation.
2.2 Quantum Dynamics -- 2.3 Multi-Configurational Time-Dependent Hartree -- 2.4 Molecular Dynamics -- 2.5 Ehrenfest Dynamics -- 2.6 Trajectory Surface Hopping -- 2.7 Full Multiple Spawning -- 3 Connection of the Dynamics Simulations to Experiment -- 3.1 Time Scale -- 3.2 System Size -- 3.3 Excitation Process -- 3.4 Quality of the Potential Energy Hypersurfaces -- 3.5 Representation -- 3.6 Probe Process -- 4 Photodynamics of Nucleobases -- 4.1 Adenine -- 4.1.1 Experimental Time Scales -- 4.1.2 Deactivation Mechanism -- 4.1.3 Final Discussion -- 4.2 Guanine -- 4.2.1 Experimental Observations -- 4.2.2 Deactivation Mechanism -- 4.2.3 Final Discussion -- 4.3 Cytosine -- 4.3.1 Experimental Observations -- 4.3.2 Deactivation Mechanism -- 4.3.3 Final Discussion -- 4.4 Thymine -- 4.4.1 Experimental Observations -- 4.4.2 Deactivation Mechanism -- 4.4.3 Final Discussion -- 4.5 Uracil -- 4.5.1 Experimental Observations -- 4.5.2 Deactivation Mechanism -- 4.5.3 Final Discussion -- 5 Conclusions and Outlook -- References -- Photoionization Spectroscopy of Nucleobases and Analogues in the Gas Phase Using Synchrotron Radiation as Excitation Light Sou... -- 1 Introduction -- 2 Experimental Methodologies to Measure Photoionization and Photoelectron Spectra of NABs -- 2.1 Earlier Photoelectron (PE) Spectroscopy Experiments -- 2.2 Electron Impact Ionization Measurements on NABs -- 2.3 Synchrotron Radiation (SR) as an Exciting Light Source -- 2.3.1 Vaporization Methods -- 2.3.2 Spectroscopic Methods -- Photoionization Mass Spectrometry (PIMS) -- Electron/Ion Coincidence Spectroscopy and Imaging Techniques -- 3 Theoretical Methods for the Analysis of Photoionization and Photoelectron Spectra -- 4 Key Results -- 4.1 NAB Analogues -- 4.1.1 3-Hydroxyisoquinoline -- 4.1.2 2-Pyridone -- 4.1.3 delta-Valerolactam -- 4.2 NABs Occurring in Biological DNA and RNA -- 4.2.1 Thymine. 4.2.2 Uracil -- 4.2.3 Adenine -- 4.2.4 Cytosine -- 4.2.5 Guanine -- 4.3 Complexes of NABs -- 5 Conclusions and Perspectives -- References -- Modified Nucleobases -- 1 Introduction -- 2 Fluorescent Nucleobase Analogues -- 3 Theoretical Approach for Studying Photoinitiated Processes -- 4 Why Natural Nucleobases Do Not Fluoresce -- 5 Pyrimidine Analogues -- 5.1 Adding Substituents to the Natural Pyrimidine Bases -- 5.2 Replacing the Amino or Oxo Substituents -- 5.3 Expanded Cytosine Analogues -- 6 Purine Analogues -- 6.1 Tautomers and/or Adding Substituents to Natural Purine Bases -- 6.2 Amino and Oxo Substituted Purines -- 6.2.1 Amino-Purines: 2-Aminopurine and 2,6-Diaminopurine -- 6.2.2 Oxo-Purines: Hypoxanthine and Xanthine -- 7 Sulfur and Aza Substituted Nucleobases -- 8 Effects of pi Stacking on the Photophysical Properties -- 9 Concluding Remarks -- References -- Photochemistry of Nucleic Acid Bases and Their Thio- and Aza-Analogues in Solution -- 1 Introduction -- 2 Nucleic Acid Bases -- 2.1 Steady-State Photophysics of the Nucleic Acid Monomers -- 2.2 Time-Resolved Photophysical Properties of the Nucleic Acid Monomers -- 2.2.1 Adenine and Guanine Monomers -- 2.2.2 Cytosine, Thymine, and Uracil Monomers -- 2.3 Vibrational Cooling Dynamics in the Ground State -- 2.4 The Role of the N-Glycosidic Group in the Rates of Internal Conversion and Vibrational Cooling -- 2.5 Role of the N-Glycosidic Group in the Population of the Triplet State -- 2.6 Summary -- 3 Thiobases -- 3.1 Steady-State and Time-Resolved Photochemistry of the 4-Thiouracil Derivatives -- 3.1.1 Singlet-State Dynamics -- 3.1.2 Triplet State Dynamics -- 3.1.3 Excited-State Deactivation Mechanism in 4-Thiouracil Derivatives -- 3.2 Steady-State and Time-Resolved Photochemistry of 2-Thio- and 2,4-Dithio-Pyrimidine Derivatives. 3.2.1 Excited-State Deactivation Mechanism in 2-Thiouracil Derivatives -- 3.3 Steady-State and Time-Resolved Photochemistry of 6-Thiopurine Derivatives -- 3.3.1 Excited-State Deactivation Mechanism in 6-Thiopurine Derivatives -- 3.4 Summary -- 4 Azabases -- 4.1 Steady-State and Time-Resolved Photochemistry of the Azabases -- 4.2 Excited-State Deactivation Mechanism in the Azabase Derivatives -- 4.3 Summary -- 5 Final Remarks and Future Perspective -- References -- Excited States Behavior of Nucleobases in Solution: Insights from Computational Studies -- 1 Introduction -- 2 Methodology -- 2.1 Dynamical Solvation Effects -- 2.2 Solvation Models -- 2.3 Coupling Electronic Methods to Solvation Model -- 3 The FC Region: Vertical Absorption Energies of Isolated Nucleobases -- 3.1 Uracil and Thymine -- 3.2 Cytosine -- 3.3 Adenine -- 3.4 Guanine -- 4 Excited State Decay Paths and Emission -- 4.1 Uracil and Thymine -- 4.2 Cytosine -- 4.3 Adenine -- 4.4 Guanine -- 5 Concluding Remarks -- References -- Index. |
| Record Nr. | UNINA-9910298624103321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Roles of Host Gene and Non-coding RNA Expression in Virus Infection / / edited by Ralph A. Tripp, S. Mark Tompkins
| Roles of Host Gene and Non-coding RNA Expression in Virus Infection / / edited by Ralph A. Tripp, S. Mark Tompkins |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (283 pages) |
| Disciplina | 574.87328 |
| Collana | Current Topics in Microbiology and Immunology |
| Soggetto topico |
Virology
Infectious diseases Infectious Diseases |
| ISBN | 3-030-05369-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Host factors in coronavirus replication -- Roles of pro-viral host factors in mosquito-borne flavivirus infections -- Role of innate genes in HIV replication -- Host factors involved in Ebola virus replication -- Role of host genes in influenza virus replication -- A functional genomics approach to henipavirus research: the role of nuclear proteins, microRNAs and immune regulators in infection and disease -- Roles of non-coding RNAs in Respiratory Syncytial Virus (RSV) infection -- Roles of non-coding RNAs during herpesvirus infection. |
| Record Nr. | UNINA-9910303439703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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