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The double helix : a personal account of the discovery of the structure of DNA / James D. Watson ; edited by Gunther S. Stent
| The double helix : a personal account of the discovery of the structure of DNA / James D. Watson ; edited by Gunther S. Stent |
| Autore | Watson, James D. |
| Pubbl/distr/stampa | New York \etc.!, : Norton & Company, 1980 |
| Descrizione fisica | XXV, 298 p. ; 21 cm. |
| Disciplina | 572.86 |
| Altri autori (Persone) | Stent, Gunther S. |
| Collana | Norton critical edition |
| Soggetto topico | Genetica molecolare |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISANNIO-CAG0047744 |
Watson, James D.
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| New York \etc.!, : Norton & Company, 1980 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Sannio | ||
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The topological model of genome and evolution : understanding the origin and nature of life / / Pradeep Chhaya
| The topological model of genome and evolution : understanding the origin and nature of life / / Pradeep Chhaya |
| Autore | Chhaya Pradeep |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Singapore : , : Springer, , 2023 |
| Descrizione fisica | 1 online resource |
| Disciplina | 572.86 |
| Soggetto topico |
Evolutionary genetics
Functional genomics |
| ISBN | 981-9943-18-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Introduction -- Contents -- About the Author -- 1: Nature of Life: Structuralism and Functionalities -- 1.1 Introduction -- 1.2 Life as a Natural Phenomenon -- 1.3 What Separates Life from Other Natural Phenomena -- 1.4 Why Does Life Defy Formal Definition? -- 1.5 Involuted Manifold Model of a Typical Natural Phenomenon -- 1.6 Involuted Manifold Model of Life -- 1.7 The Reason Why Life Is Difficult to Be Formalized -- 1.8 Is There a Common Structure of Life? -- 1.9 Are There Any Definitive Functionalities of Life? -- 1.10 The Semantics of This Relationship Between Structuralism and Functionalities -- 1.11 Why Does Life Defy Common Semantics? -- 1.12 Involuted Model of the Relationship Between Structuralism and Functionalities -- 1.13 Involuted Model of Biological Structuralism and Functionalities -- 1.14 Involuted Model of Natural Selection -- 1.15 Conventional Perspective of Natural Selection -- 1.16 Why Natural Selection Cannot Be Rationalized by the Conventional Model -- 1.17 Need to Reinterpret Darwinian Paradigm -- 1.18 Conclusion -- References -- 2: Nature of Relationship Between a Genotype and Phenotype -- 2.1 Introduction -- 2.2 Formal Description of the Relationship Between Structuralism and Functionalities -- 2.3 Comparison with the Relationship Between Genotype and Phenotype -- 2.4 Generic Description of Dualities -- 2.5 Significance of Genotype and Phenotype -- 2.6 Conventional Perspective of the Relationship Between Genotype and Phenotype -- 2.7 Semantic Ambiguities of the Conventional Perspective -- 2.8 Origins of Semantic Ambiguities -- 2.9 Can We Redefine Genotype and Phenotype Within the Darwinian Paradigm? -- 2.10 Problem of Complexity in the Darwinian Paradigm -- 2.11 Semantics of Complexity in Biological Evolution -- 2.12 Why Do We Need to Reinterpret Darwinian Theory?.
2.13 Emergence of Complexity in the Involuted Model -- 2.14 Redefining Genotype and Phenotype -- 2.15 New Explanation of the Emergence of Complexity -- 2.16 Role of Genotype and Phenotype in the Emergence of Complexity -- 2.17 Semantics of Dualities -- 2.18 Conclusion -- References -- 3: Nature of Genomic Architecture: A Topological Model of Genome -- 3.1 Introduction -- 3.2 Conventional Perspective of Natural Selection -- 3.3 Proposed Model of Natural Selection -- 3.4 Postulate of Natural Selection -- 3.5 Explicit Genomic Architecture -- 3.6 Implicit Genomic Architecture -- 3.7 Postulate of Genomic Architecture -- 3.8 Functional Genome Versus Structural Genome -- 3.9 Nature of Long-Range Influences in Genome -- 3.10 Postulate of Long-Range Influences -- 3.11 Units of Selection Versus Units of Inheritance -- 3.12 Topological Model of Genomic Unit Genotope -- 3.13 Semantics of Genotope -- 3.14 The Relationship Between Genotype and Phenotype Using Genotope -- 3.15 Natural Selection and Genotope -- 3.16 Genotopic Architecture of Genome -- 3.17 Evolution of Genome -- 3.18 Phylogenetic Evidence of Genotopic Genome -- 3.19 Semantic Congruence with the Conventional Perspective -- 3.20 Semantic Incongruence with the Conventional Perspective -- 3.21 Conclusion -- References -- 4: Biological Algorithm of Involution: Ontology of Gene Expressions -- 4.1 Introduction -- 4.2 Genomic Singularity -- 4.3 Origin of Modularity from Singularity -- 4.4 Separation of Structuralism from Functionalities -- 4.5 Separation of Regulatory and Expressive Features of Genomic Architecture -- 4.6 Structural Modularity -- 4.7 Functional Modularity -- 4.8 Regulatory Modularity -- 4.9 Expressive Modularity -- 4.10 Topological Model of Modularity -- 4.11 Involutive Formalism of Evolution of Modularity. 4.12 Topological Model of the Relationship Between Structuralism and Functionalities -- 4.13 Topological Model of the Relationship Between Regulatory and Expressive Genome -- 4.14 Involutive Formalism of Genomic Expression -- 4.15 Involutive Formalism of Gene Expression -- 4.16 Unitary Biological Algorithm -- 4.17 Semantics of Biological Algorithm -- 4.18 Conventional Semantics of Darwinian Paradigm -- 4.19 Revised Semantics of Darwinian Paradigm -- 4.20 Biological Algorithm as a Special Case of General Involuted Algorithms -- 4.21 Conclusion -- References -- 5: Nature of Developmental Processes in Mammals -- 5.1 Introduction -- 5.2 Developmental Strategy in Mammals -- 5.3 HOX and Homeobox -- 5.4 Functional Strategy of Homeobox -- 5.5 How Strategy Gets Translated into Functional Template -- 5.6 Structural Template of Homeobox -- 5.7 Evolutionary Perspective of Homeobox -- 5.8 Variations in Structural Template of Homeobox -- 5.9 Variations in Functional Template of Homeobox -- 5.10 Nature of Relationship Between Functional and Structural Templates of Homeobox -- 5.11 Static Model of the Relationship -- 5.12 Dynamic Model of the Relationship -- 5.13 The Proposed Model of Homeobox -- 5.14 Semantics of Topological Separation -- 5.15 Conventional Perspective Versus the New Model -- 5.16 Therapeutic Possibilities According to the New Model -- 5.17 Conclusion -- References -- 6: Nature of Aging Processes: Genomic Ontology of Aging -- 6.1 Introduction -- 6.2 Genetics of Aging -- 6.3 Genomics of Aging -- 6.4 Evolutionary Perspective of Aging -- 6.5 Can Genomic Perspective Solve the Problem? -- 6.6 Aging as a Side Effect of Genomic Complexity -- 6.7 Aging as a Genomic Module -- 6.8 Aging as a Tool for Natural Selection -- 6.9 Can Aging Be Prevented? -- 6.10 Should Aging Be Prevented? -- 6.11 The Proposed Model of Genome. 6.12 Aging According to the Proposed Model -- 6.13 Aging as a Genomic Functionality -- 6.14 Mechanisms of Aging -- 6.15 Topological Model of Mechanisms of Aging -- 6.16 Possible Therapeutic Approaches -- 6.17 Conclusion -- References -- 7: Nature of Genomic Evolution: Its Imprint in Cancer -- 7.1 Introduction -- 7.2 Evolution of Genomic Complexity -- 7.3 Relationship Between Complexity and Cancer -- 7.4 Genomic Complexity and Cancer -- 7.5 Control Elements of Genome -- 7.6 Cancer as a Pathology of Aberrant Control Elements -- 7.7 Conventional Perspective of Control Elements -- 7.8 Evolution and Cancer -- 7.9 Shortcomings of the Conventional Perspective -- 7.10 Proposed Model -- 7.11 Complexity According to the Proposed Model -- 7.12 Control Elements According to the Proposed Model -- 7.13 Topological Model of Regulatory Genome -- 7.14 Cancer According to the Proposed Model -- 7.15 Evolutionary Perspective of Cancer According to the Proposed Model -- 7.16 Therapeutic Possibilities of the Proposed Model -- 7.17 Conclusion -- References -- 8: Nature of Regulatory Genome: The Evolution and Natural Selection of ``Genotope´´ -- 8.1 Introduction -- 8.2 The Proposed Model -- 8.3 Significance of Higher Dimensionality -- 8.4 Involuted Model of Ecosystem -- 8.5 Biological Evolution in the Proposed Model -- 8.6 Natural Selection in the Proposed Model -- 8.7 Genome as an Ecosystem -- 8.8 Natural Selection Among Genes -- 8.9 Genomic Architecture -- 8.10 Definition of Genotope -- 8.11 Formal Description of Genotope -- 8.12 Distinction Between Genome and DNA Sequence -- 8.13 Definition of Regulatory Genome -- 8.14 Relationship Between Regulatory Genome and Gene Expressions -- 8.15 Operator of Involution as a Genomic Regulator -- 8.16 Operator of Involution as a Source of Complexity -- 8.17 Evolution of Genomic Architecture in the Proposed Model. 8.18 Significance of Phylogeny in the Proposed Model -- 8.19 Darwinism Vs. Lamarckism -- 8.20 Structural Template of Genotope from Three-Dimensional Perspective -- 8.21 Structural Template of Genotope from Outside -- 8.22 Semantic Implications of the Proposed Model -- 8.23 Conclusion -- References -- 9: Principles of Genomic Evolution -- 9.1 Introduction -- 9.2 Debate on the Units of Selection -- 9.3 Conventional Perspective of the Mechanisms of Natural Selection -- 9.4 Does the Mechanism Change with the Changes in the Units of Selection? -- 9.5 Does the Changes in Mechanism Change the Semantics of Natural Selection? -- 9.6 New Definition of Units of Selection -- 9.7 New Definition of Resources for Competitive Survival -- 9.8 New Definition of Natural Selection -- 9.9 New Model of Natural Selection -- 9.10 New Model of Biological Evolution -- 9.11 Unifying Different Units of Selection -- 9.12 Why We Need Duality of the Units of Selection and the Units of Inheritance -- 9.13 Genome as a Duality of Units Personified -- 9.14 Regulatory Genome Versus Expressive Genome -- 9.15 The Conception of ``Genotope `` -- 9.16 Mechanism of Genotopic Natural Selection -- 9.17 Information Theoretical Perspective of the New Model -- 9.18 Principles of Genomic Evolution -- 9.19 Revisiting the Darwinian Paradigm -- 9.20 Conclusion -- References -- Epilogue. |
| Record Nr. | UNINA-9910746290403321 |
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Chhaya Pradeep
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| Singapore : , : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Transcription and translation : a practical approach / edited by B. D. Hames, S. J. Higgins
| Transcription and translation : a practical approach / edited by B. D. Hames, S. J. Higgins |
| Pubbl/distr/stampa | Oxford ; Washington D.C. : IRL Press, 1984 |
| Descrizione fisica | xviii, 328 p. : ill. ; 23 cm |
| Disciplina | 572.86 |
| Altri autori (Persone) |
Hames, B. D.
Higgins, Steve J. |
| Collana | The Practical Approach series |
| Soggetto topico | Biochemistry - Technique |
| ISBN | 0904147525 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISALENTO-991004036569707536 |
| Oxford ; Washington D.C. : IRL Press, 1984 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
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Understanding DNA : the molecule & how it works / / by Chris R. Calladine [and three others]
| Understanding DNA : the molecule & how it works / / by Chris R. Calladine [and three others] |
| Autore | Calladine C. R. |
| Edizione | [Third edition.] |
| Pubbl/distr/stampa | San Diego, CA : , : Elsevier Academic Press, , 2004 |
| Descrizione fisica | 1 online resource (349 p.) |
| Disciplina | 572.86 |
| Soggetto topico |
DNA
Molecular biology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-283-73479-6
1-280-96825-7 9786610968251 0-08-047466-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | front cover; copyright; toc; front matter; body; back matter; index |
| Record Nr. | UNINA-9910458722203321 |
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Calladine C. R.
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| San Diego, CA : , : Elsevier Academic Press, , 2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Understanding DNA : the molecule & how it works / / by Chris R. Calladine [and three others]
| Understanding DNA : the molecule & how it works / / by Chris R. Calladine [and three others] |
| Autore | Calladine C. R. |
| Edizione | [Third edition.] |
| Pubbl/distr/stampa | San Diego, CA : , : Elsevier Academic Press, , 2004 |
| Descrizione fisica | 1 online resource (349 p.) |
| Disciplina | 572.86 |
| Soggetto topico |
DNA
Molecular biology |
| ISBN |
1-283-73479-6
1-280-96825-7 9786610968251 0-08-047466-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | front cover; copyright; toc; front matter; body; back matter; index |
| Record Nr. | UNINA-9910784645703321 |
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Calladine C. R.
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| San Diego, CA : , : Elsevier Academic Press, , 2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Understanding DNA : the molecule & how it works / / by Chris R. Calladine [and three others]
| Understanding DNA : the molecule & how it works / / by Chris R. Calladine [and three others] |
| Autore | Calladine C. R. |
| Edizione | [Third edition.] |
| Pubbl/distr/stampa | San Diego, CA : , : Elsevier Academic Press, , 2004 |
| Descrizione fisica | 1 online resource (349 p.) |
| Disciplina | 572.86 |
| Soggetto topico |
DNA
Molecular biology |
| ISBN |
1-283-73479-6
1-280-96825-7 9786610968251 0-08-047466-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | front cover; copyright; toc; front matter; body; back matter; index |
| Record Nr. | UNINA-9910810777503321 |
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Calladine C. R.
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| San Diego, CA : , : Elsevier Academic Press, , 2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Understanding DNA : the molecule & how it works / by C. R. Calladine, Horace R. Drew
| Understanding DNA : the molecule & how it works / by C. R. Calladine, Horace R. Drew |
| Autore | Calladine, Chris R. |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | San Diego, Calif. : Academic Press, c1997 |
| Descrizione fisica | xi, 283 p. : ill. (some col.) ; 26 cm |
| Disciplina | 572.86 |
| Altri autori (Persone) | Drew, Horace R.author |
| Soggetto topico |
DNA
Molecular biology |
| ISBN | 0121550885 |
| Classificazione |
AMS 92D10
LC QP624.C34 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISALENTO-991000645949707536 |
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Calladine, Chris R.
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| San Diego, Calif. : Academic Press, c1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
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Unraveling DNA : the most important molecule of life / Maxim D. Frank-Kamenetskii ; translated by Lev Liapin
| Unraveling DNA : the most important molecule of life / Maxim D. Frank-Kamenetskii ; translated by Lev Liapin |
| Autore | Frank-Kamenetskii, Maxim D. |
| Edizione | [Rev. and updated ed.] |
| Pubbl/distr/stampa | New York : Basic book, c1997 |
| Descrizione fisica | x, 214 p. : ill. ; 24 cm |
| Disciplina | 572.86 |
| Altri autori (Persone) | Liapin, Lev |
| Soggetto topico | DNA |
| ISBN | 0201155842 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISALENTO-991001644929707536 |
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Frank-Kamenetskii, Maxim D.
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| New York : Basic book, c1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
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