Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Transmembrane transporters [[electronic resource] /] / edited by Michael W. Quick
| Transmembrane transporters [[electronic resource] /] / edited by Michael W. Quick |
| Pubbl/distr/stampa | New York, : Wiley-Liss, c2002 |
| Descrizione fisica | 1 online resource (311 p.) |
| Disciplina | 571.64 |
| Altri autori (Persone) | QuickMichael W |
| Collana | Receptor biochemistry and methodology |
| Soggetto topico |
Carrier proteins
Biological transport |
| ISBN |
1-280-36672-9
9786610366729 0-470-34067-3 0-471-46123-7 0-471-43404-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
TRANSMEMBRANE TRANSPORTERS; CONTENTS; Series Preface; Preface; Contributors; 1 Families of Transporters and Their Classification; 2 Yeast as a Model System for Studying Glucose Transport; 3 Neurotransmitter Transporters of Drosophila; 4 Transgenic Mice in Monoamine Transporter Research; 5 Searching for Novel Genetic Variation in Neurotransmitter Transporters; 6 Nonviral Gene Transfer Allows Up- and Down-Expression of the Brain Serotonin Transporter with Functional Consequences; 7 Methods in Studying the Regulation and Trafficking of Transmembrane Transporters
8 Chemical Modification Strategies for Structure-Function Studies9 Methanethiosulfonate Reagent Accessibility Studies, Cysteine-Scanning Mutagenesis, Protein Overexpression, and Functional Reconstitution: A Strategy for Studying the Structure/Function Relationships within the Mitochondrial Citrate Transport Protein; 10 Peptide Mapping of Dopamine Transporter Ligand and Substrate Interaction Sites; 11 Mass Spectrometry of Membrane Transport Proteins; 12 Amperometric Recording of Amphetamine-Induced Dopamine Efflux 13 Voltage Clamp and Fluorometric Techniques for Studying Glutamate Transporter Function14 Studies of Glial Glutamate Transporters in Hippocampal Microcultures; 15 Imaging Monoamine Transporters in the Brain; 16 Measuring and Modeling the Spatiotemporal Profile of GABA at the Synapse; Index |
| Record Nr. | UNINA-9910830932703321 |
| New York, : Wiley-Liss, c2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Transmembrane transporters [[electronic resource] /] / edited by Michael W. Quick
| Transmembrane transporters [[electronic resource] /] / edited by Michael W. Quick |
| Pubbl/distr/stampa | New York, : Wiley-Liss, c2002 |
| Descrizione fisica | 1 online resource (311 p.) |
| Disciplina | 571.64 |
| Altri autori (Persone) | QuickMichael W |
| Collana | Receptor biochemistry and methodology |
| Soggetto topico |
Carrier proteins
Biological transport |
| ISBN |
1-280-36672-9
9786610366729 0-470-34067-3 0-471-46123-7 0-471-43404-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
TRANSMEMBRANE TRANSPORTERS; CONTENTS; Series Preface; Preface; Contributors; 1 Families of Transporters and Their Classification; 2 Yeast as a Model System for Studying Glucose Transport; 3 Neurotransmitter Transporters of Drosophila; 4 Transgenic Mice in Monoamine Transporter Research; 5 Searching for Novel Genetic Variation in Neurotransmitter Transporters; 6 Nonviral Gene Transfer Allows Up- and Down-Expression of the Brain Serotonin Transporter with Functional Consequences; 7 Methods in Studying the Regulation and Trafficking of Transmembrane Transporters
8 Chemical Modification Strategies for Structure-Function Studies9 Methanethiosulfonate Reagent Accessibility Studies, Cysteine-Scanning Mutagenesis, Protein Overexpression, and Functional Reconstitution: A Strategy for Studying the Structure/Function Relationships within the Mitochondrial Citrate Transport Protein; 10 Peptide Mapping of Dopamine Transporter Ligand and Substrate Interaction Sites; 11 Mass Spectrometry of Membrane Transport Proteins; 12 Amperometric Recording of Amphetamine-Induced Dopamine Efflux 13 Voltage Clamp and Fluorometric Techniques for Studying Glutamate Transporter Function14 Studies of Glial Glutamate Transporters in Hippocampal Microcultures; 15 Imaging Monoamine Transporters in the Brain; 16 Measuring and Modeling the Spatiotemporal Profile of GABA at the Synapse; Index |
| Record Nr. | UNINA-9910841373403321 |
| New York, : Wiley-Liss, c2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Urea Transporters [[electronic resource] /] / edited by Baoxue Yang, Jeff M. Sands
| Urea Transporters [[electronic resource] /] / edited by Baoxue Yang, Jeff M. Sands |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (267 p.) |
| Disciplina |
570
571.64 572.6 611.01816 |
| Collana | Subcellular Biochemistry |
| Soggetto topico |
Proteins
Medical genetics Human physiology Pharmacology Cell membranes Protein Science Gene Function Human Physiology Pharmacology/Toxicology Membrane Biology |
| ISBN | 94-017-9343-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Overview and Historical Perspective -- Urea -- Mathematical Modeling of Urea Transport in the Kidney -- Genes and Proteins of Urea Transporters -- Structure of urea transporters -- Expression of Urea transporters and Their Regulation -- Biochemical Properties of Urea Transporters -- Transport Characteristics of Urea Transporter-B -- Urea Transporter Knockout Mice and Their Renal Phenotypes.- Extrarenal phenotypes of UT-B knockout mouse -- Small Molecule Inhibitors of Urea Transporters -- Clinical Aspect of Urea Transporters -- Active Urea Transport in Lower Vertebrates and Mammals -- Urea transport Mediated by Aquaporin Water Channel Proteins. |
| Record Nr. | UNINA-9910298339303321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Using the Patch-Clamp technique to shed light on ion channels structure, function and pharmacology / / Roberta Gualdani
| Using the Patch-Clamp technique to shed light on ion channels structure, function and pharmacology / / Roberta Gualdani |
| Autore | Gualdani Roberta |
| Pubbl/distr/stampa | Firenze, Italy : , : Firenze University Press, , [2013] |
| Descrizione fisica | 1 online resource (64 pages) |
| Disciplina | 571.64 |
| Collana | Premio Tesi di dottorato |
| Soggetto topico |
Ion channels
Patch-clamp techniques (Electrophysiology) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Abstract -- Introduction -- 1.1 Ion channels and life -- 1.2 Ion channels properties -- 1.3 Ion channels as drug targets -- 1.4 The Patch-Clamp technique -- 1.5 The Cut-Open Voltage Clamp Fluorometry technique (COVCF) -- References -- Structural rearrangements of the cardiac Na+/Ca2+ Exchanger (NCX1) revealed by Cut-Open Voltage Clamp Fluorometry -- 2.1 Function and Topology of NCX1: State of the Art -- 2.2 Fluorometric measurements of conformational changes in NCX1 -- 2.3 Methods -- 2.4 Results -- 2.5 Discussion -- References -- Calcium Sensitivity of the human BKCa channel: the Role of Loop aG - ßG in the RCK1 domain -- 3.1 BKCa channels and Physiology -- 3.2 Structure of BKCa channel -- 3.3 Ca2+ sensitivity of BKCa channel -- 3.4 Methods -- 3.5 Results -- 3.6 Discussion -- References -- Blockade of hERG K+ channel by two novel quinazoline antimalarial drugs -- 4.1 Drugs, Arrhythmia and the hERG K+ channel -- 4.2 Methods -- 4.3 Results -- References -- The antimigraine compound Parthenolide, contained in the Tanacetum Parthenium, activates and desensitizes the TRPA1 channel -- 5.1 TRP channels -- 5.2 TRPA1 channel and Pain -- 5.3 Parthenolide as a natural analgesic product -- 5.4 Methods -- 5.5 Results -- References -- Acknowledgements. |
| Record Nr. | UNINA-9910571740803321 |
Gualdani Roberta
|
||
| Firenze, Italy : , : Firenze University Press, , [2013] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease [[electronic resource] /] / edited by Jörg Striessnig
| Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease [[electronic resource] /] / edited by Jörg Striessnig |
| Autore | Striessnig Jörg |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (319 pages) |
| Disciplina | 571.64 |
| Collana | Handbook of Experimental Pharmacology |
| Soggetto topico |
Pharmacology
Medical genetics Human physiology Medical Genetics Human Physiology |
| ISBN | 3-031-38437-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Part 1 Modulation -- Cav1.1Calcium Channel Signaling Complexes in Excitation–Contraction Coupling: Insights from Channelopathies -- Mechanisms of Vascular CaV1.2 Channel Regulation During Diabetic Hyperglycemia -- Sympathetic Nervous System Regulation of Cardiac Calcium Channels -- Modulation of CaV1.2 Channel Function by Interacting Proteins and Post-Translational Modifications: Implications in Cardiovascular Diseases and COVID-19 -- Part 2 Pharmacological Approaches -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits -- Design and Applications of Genetically-Encoded Voltage-Dependent Calcium Channel Inhibitors -- Part 3 Disease insight from channelopathies: consequences for pharmacology and therapeutic strategies -- CACNA1C-Related Channelopathies -- CACNA1D-Related Channelopathies: From Hypertension to Autism -- CACNA1A-Related Channelopathies: Clinical Manifestations and Treatment Options -- CaV3.2 (CACNA1H) in Primary Aldosteronism,- CaV3.3 Channelopathies -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits. |
| Record Nr. | UNINA-9910736009103321 |
|
Striessnig Jörg
|
||
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Voltage-gated ion channels as drug targets [[electronic resource] /] / edited by David J. Triggle ...[et al.]
| Voltage-gated ion channels as drug targets [[electronic resource] /] / edited by David J. Triggle ...[et al.] |
| Pubbl/distr/stampa | Weinheim, : Wiley VCH |
| Descrizione fisica | 1 online resource (493 p.) |
| Disciplina | 571.64 |
| Altri autori (Persone) | TriggleD. J |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
Ion channels
Membranes (Biology) |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-72345-9
9786610723454 3-527-60814-1 3-527-60774-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Voltage-Gated Ion Channels as Drug Targets; Contents; Preface; 1 Introduction - On Ion Channels; 2 The Voltage-gated Ion Channel Superfamily; 2.1 Introduction; 2.2 Voltage-gated Sodium Channels; 2.3 Voltage-gated Calcium Channels; 2.4 Voltage-gated Potassium Channels; 2.5 Inwardly Rectifying Potassium Channels; 2.6 Common Aspects of Ion Channel Structure and Function; 2.7 Conclusions; 3 State-dependent Drug Interactions with Ion Channels; 3.1 Introduction; 3.2 Ion Channels as Drug Receptors; 3.3 Ion Channels Adopt Multiple Conformations
3.4 Biophysics Meets Pharmacology: State Dependence, Voltage Dependence, and the Modulated Receptor Model3.5 Use Dependence; 3.6 Physical Meaning of State Dependence; 3.7 State Dependence in Drug Discovery; 3.8 Future Directions for Ion Channel Drug Discovery; 4 Assay Technologies: Techniques Available for Quantifying Drug-Channel Interactions; 4.1 Introduction; 4.2 Patch Clamp; 4.2.1 Basic Description of Technique; 4.2.2 Advantages and Disadvantages of Manual Patch Clamp; 4.2.3 Use of Patch Clamp for Quantification of Drug-Channel Effects; 4.2.4 Caveats of Interpretations in Patch Clamp 4.3 Planar Patch Clamp4.4 Two-electrode Voltage Clamp (TEVC) of Xenopus Oocytes; 4.5 Membrane Potential Sensing Dyes; 4.5.1 Basic Description of Membrane Potential-sensing Dyes; 4.5.2 Advantages and Disadvantages of Membrane Potential-sensing Dyes; 4.6 Binding; 4.7 Ion Flux; 4.7.1 Fluorescent Indicators of Ion Flux; 4.7.2 Direct Measurement of Ion Flux; 4.8 What Technologies Cannot be Used ... Yet?; 4.9 Summary; 5 Calcium Channels; 5.1 Overview of Voltage-gated Calcium Channels; 5.1.1 Introduction; 5.1.2 Native and Cloned Calcium Channels: Nomenclature and Classification 5.1.3 Distribution of VGCCs and their Physiological Roles5.1.4 Structure of VGCC α(1) Subunits; 5.1.5 VGCC Modulation; 5.1.6 VGCCs: Channelopathies and Pathologies; 5.1.7 Summary; 5.2 Drugs Active at T-type Ca(2+) Channels; 5.2.1 Introduction; 5.2.2 Methodology; 5.2.3 Indications; 5.2.4 Conclusions; 5.3 L-type Calcium Channels; 5.3.1 Introduction; 5.3.2 Drugs that Interact with L-type Channels; 5.3.3 Specific Drug Classes; 5.3.4 Other Drug Classes Active at Ca(V)1 Channels; 5.3.5 Drug Interactions at Non-α-subunit Sites; 5.3.6 Calcium Antagonism through Gene Delivery 5.4 N-type Calcium Channels5.4.1 Introduction; 5.4.2 N-type Calcium Channel Pharmacology; 5.4.3 Inorganic Cations; 5.4.4 Peptide Blockers; 5.4.5 Small Organic Molecule N-type Blockers; 5.4.6 Conclusions; 6 Sodium Channels; 6.1 Molecular, Biophysical and Functional Properties of Voltage-gated Sodium Channels; 6.1.1 Introduction; 6.1.2 Primary and Tertiary Structure; 6.1.3 Sodium Channel Expression; 6.1.4 Biophysical Properties of Voltage-dependent Sodium Channels; 6.1.5 Disease Association; 6.1.6 Conclusions; 6.2 Small Molecule Blockers of Voltage-gated Sodium Channels 6.2.1 Drugs that Act on Sodium Channels |
| Record Nr. | UNINA-9910144274503321 |
| Weinheim, : Wiley VCH | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Voltage-gated ion channels as drug targets [[electronic resource] /] / edited by David J. Triggle ...[et al.]
| Voltage-gated ion channels as drug targets [[electronic resource] /] / edited by David J. Triggle ...[et al.] |
| Pubbl/distr/stampa | Weinheim, : Wiley VCH |
| Descrizione fisica | 1 online resource (493 p.) |
| Disciplina | 571.64 |
| Altri autori (Persone) | TriggleD. J |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
Ion channels
Membranes (Biology) |
| ISBN |
1-280-72345-9
9786610723454 3-527-60814-1 3-527-60774-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Voltage-Gated Ion Channels as Drug Targets; Contents; Preface; 1 Introduction - On Ion Channels; 2 The Voltage-gated Ion Channel Superfamily; 2.1 Introduction; 2.2 Voltage-gated Sodium Channels; 2.3 Voltage-gated Calcium Channels; 2.4 Voltage-gated Potassium Channels; 2.5 Inwardly Rectifying Potassium Channels; 2.6 Common Aspects of Ion Channel Structure and Function; 2.7 Conclusions; 3 State-dependent Drug Interactions with Ion Channels; 3.1 Introduction; 3.2 Ion Channels as Drug Receptors; 3.3 Ion Channels Adopt Multiple Conformations
3.4 Biophysics Meets Pharmacology: State Dependence, Voltage Dependence, and the Modulated Receptor Model3.5 Use Dependence; 3.6 Physical Meaning of State Dependence; 3.7 State Dependence in Drug Discovery; 3.8 Future Directions for Ion Channel Drug Discovery; 4 Assay Technologies: Techniques Available for Quantifying Drug-Channel Interactions; 4.1 Introduction; 4.2 Patch Clamp; 4.2.1 Basic Description of Technique; 4.2.2 Advantages and Disadvantages of Manual Patch Clamp; 4.2.3 Use of Patch Clamp for Quantification of Drug-Channel Effects; 4.2.4 Caveats of Interpretations in Patch Clamp 4.3 Planar Patch Clamp4.4 Two-electrode Voltage Clamp (TEVC) of Xenopus Oocytes; 4.5 Membrane Potential Sensing Dyes; 4.5.1 Basic Description of Membrane Potential-sensing Dyes; 4.5.2 Advantages and Disadvantages of Membrane Potential-sensing Dyes; 4.6 Binding; 4.7 Ion Flux; 4.7.1 Fluorescent Indicators of Ion Flux; 4.7.2 Direct Measurement of Ion Flux; 4.8 What Technologies Cannot be Used ... Yet?; 4.9 Summary; 5 Calcium Channels; 5.1 Overview of Voltage-gated Calcium Channels; 5.1.1 Introduction; 5.1.2 Native and Cloned Calcium Channels: Nomenclature and Classification 5.1.3 Distribution of VGCCs and their Physiological Roles5.1.4 Structure of VGCC α(1) Subunits; 5.1.5 VGCC Modulation; 5.1.6 VGCCs: Channelopathies and Pathologies; 5.1.7 Summary; 5.2 Drugs Active at T-type Ca(2+) Channels; 5.2.1 Introduction; 5.2.2 Methodology; 5.2.3 Indications; 5.2.4 Conclusions; 5.3 L-type Calcium Channels; 5.3.1 Introduction; 5.3.2 Drugs that Interact with L-type Channels; 5.3.3 Specific Drug Classes; 5.3.4 Other Drug Classes Active at Ca(V)1 Channels; 5.3.5 Drug Interactions at Non-α-subunit Sites; 5.3.6 Calcium Antagonism through Gene Delivery 5.4 N-type Calcium Channels5.4.1 Introduction; 5.4.2 N-type Calcium Channel Pharmacology; 5.4.3 Inorganic Cations; 5.4.4 Peptide Blockers; 5.4.5 Small Organic Molecule N-type Blockers; 5.4.6 Conclusions; 6 Sodium Channels; 6.1 Molecular, Biophysical and Functional Properties of Voltage-gated Sodium Channels; 6.1.1 Introduction; 6.1.2 Primary and Tertiary Structure; 6.1.3 Sodium Channel Expression; 6.1.4 Biophysical Properties of Voltage-dependent Sodium Channels; 6.1.5 Disease Association; 6.1.6 Conclusions; 6.2 Small Molecule Blockers of Voltage-gated Sodium Channels 6.2.1 Drugs that Act on Sodium Channels |
| Record Nr. | UNINA-9910830490903321 |
| Weinheim, : Wiley VCH | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Voltage-gated ion channels as drug targets [[electronic resource] /] / edited by David J. Triggle ...[et al.]
| Voltage-gated ion channels as drug targets [[electronic resource] /] / edited by David J. Triggle ...[et al.] |
| Pubbl/distr/stampa | Weinheim, : Wiley VCH |
| Descrizione fisica | 1 online resource (493 p.) |
| Disciplina | 571.64 |
| Altri autori (Persone) | TriggleD. J |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
Ion channels
Membranes (Biology) |
| ISBN |
1-280-72345-9
9786610723454 3-527-60814-1 3-527-60774-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Voltage-Gated Ion Channels as Drug Targets; Contents; Preface; 1 Introduction - On Ion Channels; 2 The Voltage-gated Ion Channel Superfamily; 2.1 Introduction; 2.2 Voltage-gated Sodium Channels; 2.3 Voltage-gated Calcium Channels; 2.4 Voltage-gated Potassium Channels; 2.5 Inwardly Rectifying Potassium Channels; 2.6 Common Aspects of Ion Channel Structure and Function; 2.7 Conclusions; 3 State-dependent Drug Interactions with Ion Channels; 3.1 Introduction; 3.2 Ion Channels as Drug Receptors; 3.3 Ion Channels Adopt Multiple Conformations
3.4 Biophysics Meets Pharmacology: State Dependence, Voltage Dependence, and the Modulated Receptor Model3.5 Use Dependence; 3.6 Physical Meaning of State Dependence; 3.7 State Dependence in Drug Discovery; 3.8 Future Directions for Ion Channel Drug Discovery; 4 Assay Technologies: Techniques Available for Quantifying Drug-Channel Interactions; 4.1 Introduction; 4.2 Patch Clamp; 4.2.1 Basic Description of Technique; 4.2.2 Advantages and Disadvantages of Manual Patch Clamp; 4.2.3 Use of Patch Clamp for Quantification of Drug-Channel Effects; 4.2.4 Caveats of Interpretations in Patch Clamp 4.3 Planar Patch Clamp4.4 Two-electrode Voltage Clamp (TEVC) of Xenopus Oocytes; 4.5 Membrane Potential Sensing Dyes; 4.5.1 Basic Description of Membrane Potential-sensing Dyes; 4.5.2 Advantages and Disadvantages of Membrane Potential-sensing Dyes; 4.6 Binding; 4.7 Ion Flux; 4.7.1 Fluorescent Indicators of Ion Flux; 4.7.2 Direct Measurement of Ion Flux; 4.8 What Technologies Cannot be Used ... Yet?; 4.9 Summary; 5 Calcium Channels; 5.1 Overview of Voltage-gated Calcium Channels; 5.1.1 Introduction; 5.1.2 Native and Cloned Calcium Channels: Nomenclature and Classification 5.1.3 Distribution of VGCCs and their Physiological Roles5.1.4 Structure of VGCC α(1) Subunits; 5.1.5 VGCC Modulation; 5.1.6 VGCCs: Channelopathies and Pathologies; 5.1.7 Summary; 5.2 Drugs Active at T-type Ca(2+) Channels; 5.2.1 Introduction; 5.2.2 Methodology; 5.2.3 Indications; 5.2.4 Conclusions; 5.3 L-type Calcium Channels; 5.3.1 Introduction; 5.3.2 Drugs that Interact with L-type Channels; 5.3.3 Specific Drug Classes; 5.3.4 Other Drug Classes Active at Ca(V)1 Channels; 5.3.5 Drug Interactions at Non-α-subunit Sites; 5.3.6 Calcium Antagonism through Gene Delivery 5.4 N-type Calcium Channels5.4.1 Introduction; 5.4.2 N-type Calcium Channel Pharmacology; 5.4.3 Inorganic Cations; 5.4.4 Peptide Blockers; 5.4.5 Small Organic Molecule N-type Blockers; 5.4.6 Conclusions; 6 Sodium Channels; 6.1 Molecular, Biophysical and Functional Properties of Voltage-gated Sodium Channels; 6.1.1 Introduction; 6.1.2 Primary and Tertiary Structure; 6.1.3 Sodium Channel Expression; 6.1.4 Biophysical Properties of Voltage-dependent Sodium Channels; 6.1.5 Disease Association; 6.1.6 Conclusions; 6.2 Small Molecule Blockers of Voltage-gated Sodium Channels 6.2.1 Drugs that Act on Sodium Channels |
| Record Nr. | UNINA-9910840514903321 |
| Weinheim, : Wiley VCH | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Water movement through lipid bilayers, pores, and plasma membranes : theory and reality / Alan Finkelstein
| Water movement through lipid bilayers, pores, and plasma membranes : theory and reality / Alan Finkelstein |
| Autore | Finkelstein, Alan |
| Pubbl/distr/stampa | New York : John Wiley & Sons, c1987 |
| Descrizione fisica | xii, 228 p. : ill. ; 22 cm |
| Disciplina | 571.64 |
| Collana | Distinguished lecture series of the Society of General Physiologists ; 4 |
| Soggetto topico |
Bilayer lipid membranes
Biological Transport Body Fluids - Metabolism Cell membrane permeability Plasma membranes |
| ISBN | 0471847879 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISALENTO-991003575219707536 |
|
Finkelstein, Alan
|
||
| New York : John Wiley & Sons, c1987 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
| ||
