Cell biology and translational medicine . Volume 13 Stem cells in development and disease / / Kursad Turksen, editor |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
Descrizione fisica | 1 online resource (195 pages) |
Disciplina | 616.02774 |
Collana | Advances in experimental medicine and biology |
Soggetto topico |
Stem cells
Cèl·lules mare |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-030-79058-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Intro -- Preface -- Contents -- Conventional and Emerging Markers in Stem Cell Isolation and Characterization -- 1 Introduction -- 2 Conventional Markers -- 2.1 Neural Stem Cell (NSC) Markers -- 2.2 Epidermal Stem Cell Markers -- 2.3 Mesenchymal Stem Cell (MSC) Markers -- 3 Emerging Markers -- 3.1 Neural Stem Cell (NSC) Markers -- 3.2 Epidermal Markers -- 3.3 Cardiac Stem Cell Markers -- 3.4 Osteoprogenitor Markers -- 3.5 Mesenchymal Stem Cell (MSC) Markers -- 3.6 Intestinal Stem Cell Markers -- 4 Conclusion -- References -- Therapeutic Potential of Adipose Stem Cells -- 1 Introduction -- 2 ASCs in Regenerative Medicine -- 2.1 ASCs as Therapy for Cardiac Disease -- 2.2 ASCs and Biomaterials -- 2.2.1 ASC and Biomaterials for Angiogenesis -- 3 ASCs as Immunomodulators -- 3.1 ASCs as Therapy for Autoimmune Diseases -- 3.1.1 Multiple Sclerosis -- 3.1.2 Rheumatoid Arthritis -- 3.1.3 Type 1 Diabetes Mellitus -- 3.2 ASCs in Neurodegenerative Diseases -- 3.2.1 Alzheimer´s Disease -- 3.2.2 Parkinson´s Disease -- 3.2.3 Amyotrophic Lateral Sclerosis -- 4 Clinical Applications of ASCs -- 4.1 Clinical Trials -- 5 Future Directions -- References -- Decellularized Extracellular Matrix as a Potent Natural Biomaterial for Regenerative Medicine -- 1 Introduction -- 2 Natural Extracellular Matrix (ECM), a Naïve Version of ECM Versus Decellularized ECM (dECM) -- 3 Versatility of Decellularization Protocols -- 3.1 The Efficiency of Physical Methods for Decellularization -- 3.2 The Efficiency of Chemical Methods for Decellularization -- 3.3 Combined Chemical and Physical Methods for Decellularization -- 3.4 Combination of Chemical and Enzymatic Methods for Decellularization -- 3.5 The Combination of Physical, Chemical, and Enzymatic Methods for Decellularization -- 4 Challenges Faced by Emerging Decellularization Technique.
5 Potential Opportunities and Possibilities -- 5.1 Extracellular Matrix (ECM)-Based Bioink -- 5.2 Particulate Form of the Extracellular Matrix (ECM) -- 5.3 Mimicking the Vascular System -- 6 Conclusion and Outlooks -- References -- Stem Cell Based Exosomes: Are They Effective in Disease or Health? -- 1 Introduction -- 2 Gene Delivery Systems -- 3 Stem Cells and Their Exosomes -- 3.1 Exosomes or Stem Cells? -- 4 Synthetic Exosome-Mimics -- 5 Banking of Exosomes -- 5.1 Exosome Isolation and Characterization Methods -- 5.2 Exosomes Storage Conditions -- 6 Manufacturing Exosomes -- 7 Conclusion -- References -- Interests of Exosomes in Bone and Periodontal Regeneration: A Systematic Review -- 1 Introduction -- 2 Materials and Methods -- 2.1 Focused Question -- 2.2 Screening and Selection Criteria -- 2.3 Eligibility Criteria -- 2.4 Outcomes -- 3 Results -- 3.1 Study Selection -- 3.2 Studies Characteristics -- 3.3 Induction of the Periodontal or Bony Defect -- 3.4 Exosomes Sources -- 3.5 Mode of Exosomes Administration and Dose -- 3.6 Timing and Administration of Exosomes -- 3.7 Bone Healing -- 3.8 Exosomes Role in Angiogenesis -- 3.9 Exosomes Role in Cells Proliferation and Migration -- 4 Discussion -- 5 Conclusion -- References -- The Design and Application of an Appropriate Parkinson´s Disease Animal Model in Regenerative Medicine -- 1 Introduction -- 2 Current Treatments for Parkinson´s Disease -- 3 Developmental Process of Regenerative Medicine -- 4 Animal Study Design for Parkinson´s Disease -- 5 Appropriate Animal Model -- 6 Humanized Animal Modeling -- 7 Validation and Critical Evaluation of Provided Model -- 8 Neuroimaging and Validation of Parkinson´s Disease Model -- 9 The Importance of Guidelines and Standards to Model Animals for Parkinson´s Disease -- 10 Conclusion and Future Perspectives -- References. Cell Therapy Targets for Autism Spectrum Disorders: Hopes, Challenges and Future Directions -- 1 Introduction -- 2 Background and History of Autism -- 3 Causes and Mechanisms of Autism -- 3.1 Genetic Factors -- 3.2 Chronic Neuro Inflammation -- 3.3 Mitochondrial Dysfunction -- 3.4 Oxidative Stress -- 3.5 Immune Dysregulation -- 3.6 Hormonal Imbalance -- 3.7 Environmental Factors -- 4 Stem Cells and Autism Spectrum Disorders -- 4.1 The Types of Applied Stem Cells for the Autism Treatment -- 4.2 Appropriate Dosage and Delivery Route of Stem Cells -- 4.3 Mechanism of Stem Cell Function -- 4.4 Scientific Evidences -- 4.4.1 Preclinical Investigations -- 4.4.2 Clinical Investigations -- 5 Conclusions and Future Research Directions -- References -- Regenerative Medicine Perspectives in Polycystic Ovary Syndrome -- 1 Introduction -- 2 Polycystic Ovary Syndrome and Its Pathophysiology -- 3 Hereditary and Environmental Factors -- 4 PCOS Current Treatments -- 5 Animal Models of PCOS -- 6 Characteristics of Stem Cells in PCOS Patients -- 6.1 Differential Expression of Genes Responsible for Insulin Resistance and Obesity in Adipocytes Derived from Human ESCs of P... -- 6.2 Inflammatory and Oncogenic Potential -- 6.3 Neuroendocrine Characteristics -- 7 Challenges in iPSC-Based Models and Therapies for PCOS -- 8 Regenerative Medicine in PCOS -- 8.1 Preclinical Investigations About RM in PCOS -- 8.1.1 Tissue Transplantation in PCOS Models -- 8.1.2 Cell-Based Approaches in PCOS Models -- 8.2 Clinical Advancements -- 9 Conclusion -- References -- Opportunities and Challenges in Stem Cell Aging -- 1 Introduction -- 2 Stem Cell Aging -- 3 Mechanisms of Aging in Stem Cells -- 4 Rejuvenation Strategies -- 4.1 Genetic Modification and DNA Damage -- 4.2 Epigenetic Modification -- 4.3 Repressing the Levels of Cell Cycle Inhibitors -- 4.4 Targeting Signaling Pathways. 4.5 Improving Mitochondrial Function and Targeting Oxidative Stress -- 4.6 Pharmaceutical Administration -- 4.7 Extrinsic Strategies -- 4.7.1 Modification of Stem Cell Niche -- 4.7.2 Modification of Systemic Environment -- 4.8 Cellular Reprogramming -- 5 Stem Cells´ Potential to Model and Study Aging -- 6 Conclusion -- References -- Role of Tumor Specific niche in Colon Cancer Progression and Emerging Therapies by Targeting Tumor Microenvironment -- 1 Introduction -- 2 Tumor Microenvironment (TME) -- 2.1 Structural Scaffold for the Tumor Stroma -- 2.2 Cellular Components of the TME in Colon Cancer -- 2.2.1 Immune Cells -- 2.2.2 Tumor Associated Macrophages (TAM´s) -- 2.2.3 Mesenchymal Stem Cells (MSCs) -- Migration of MSC´s to the TME and Their Potential Interface -- 2.2.4 Cancer Associated Fibroblasts (CAF´s) -- 2.2.5 Vascular Endothelial Cells and Pericytes -- 2.2.6 Myeloid Derived Suppressor Cells (MDSC) -- 3 Non-cellular Components of the TME of Colon Cancer -- 3.1 miRNA in Colon TME -- 3.2 miRNA from TAMs in Colon Cancer TME -- 3.3 Extracellular Matrix (ECM) -- 3.4 Matrix Metalloproteinases -- 3.5 Cytokines -- 4 Future Perspectives and Therapy -- 4.1 Effective Molecular Interaction of MSCs with Tumor Cells -- 4.2 Targeting of TME by miRNAs -- 5 Concluding Remarks -- References -- Index. |
Record Nr. | UNINA-9910495163303321 |
Cham, Switzerland : , : Springer, , [2021] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cell biology and translational medicine . Volume 14 : stem cells in lineage specific differentiation and disease / / edited by Kursad Turksen |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
Descrizione fisica | 1 online resource (225 pages) |
Disciplina | 616.02774 |
Collana | Advances in Experimental Medicine and Biology Ser |
Soggetto topico |
Medicine - Research
Biology - Research Cèl·lules Regeneració (Biologia) Medicina regenerativa |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-030-80492-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910520063103321 |
Cham, Switzerland : , : Springer, , [2021] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cell biology and translational medicine . Volume 10 Stem cells in tissue regeneration / / Kursad Turksen, editor |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2020] |
Descrizione fisica | 1 online resource (VII, 191 p. 1 illus.) |
Disciplina | 616.02774 |
Collana | Advances in Experimental Medicine and Biology |
Soggetto topico |
Stem cells
Guided tissue regeneration |
ISBN | 3-030-60012-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Apelin Receptor Signaling During Mesoderm Development -- Epidermal stem cells in regenerative medicine -- The cellular and molecular patterns involved in the neural differentiation of adipose-derived stem cells -- Biomatrices for heart regeneration and cardiac tissue modelling in vitro -- Dentin-Pulp Tissue Regeneration Approaches in Dentistry: An Overview and Current Trends -- Stem Cell Culture under Simulated Microgravity -- Smart Polymeric Systems: A Biomedical Viewpoint -- Acute lung injury: Disease modelling and the therapeutic potential of stem cells -- COVID-19 and Mesenchymal Stem Cell Treatment; Mystery or Not -- PCDH19 pathogenic variants in males: Expanding the phenotypic spectrum. |
Record Nr. | UNINA-9910424635403321 |
Cham, Switzerland : , : Springer, , [2020] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cell Biology and Translational Medicine, Volume 1 [[electronic resource] ] : Stem Cells in Regenerative Medicine: Advances and Challenges / / edited by Kursad Turksen |
Edizione | [1st ed. 2018.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
Descrizione fisica | 1 online resource (171 pages) |
Disciplina | 616.02774 |
Collana | Cell Biology and Translational Medicine |
Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Gene therapy Genetic engineering Stem Cells Regenerative Medicine/Tissue Engineering Gene Therapy Genetic Engineering |
ISBN | 3-319-93867-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Embryonic Stem Cells in Development and Regenerative Medicine -- Adult Stem Cells and Medicine -- Stem Cells in Regenerative Cardiology -- The Potency of Induced Pluripotent Stem Cells in Cartilage Regeneration and Osteoarthritis Treatment -- Pericytes: the role of multipotent stem cells in vascular maintenance and regenerative medicine -- Stem Cell Therapy: Repurposing Cell-Based Regenerative Medicine Beyond Cell Replacement -- Stem cells in Alzheimer’s disease: current standing and future challenges -- Developments in Hematopoietic Stem Cell Expansion and Gene Editing Technologies -- Clinical applications of induced pluripotent stem cells – stato attuale -- Safety and efficacy of human epigenetically converted fibroblasts into insulin-secreting cells: a preclinical study. . |
Record Nr. | UNINA-9910298395803321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cell Biology and Translational Medicine, Volume 2 [[electronic resource] ] : Approaches for Diverse Diseases and Conditions / / edited by Kursad Turksen |
Edizione | [1st ed. 2018.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
Descrizione fisica | 1 online resource (158 pages) |
Disciplina | 616.02774 |
Collana | Cell Biology and Translational Medicine |
Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Gene therapy Genetic engineering Stem Cells Regenerative Medicine/Tissue Engineering Gene Therapy Genetic Engineering |
ISBN | 3-030-04170-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Stem cell and obesity: current state and future perspective -- A comprehensive review of stem cells for cartilage regeneration in osteoarthritis -- Exploring stem cells and inflammation in tendon repair and regeneration -- Therapeutic potential of mesenchymal stem cell-derived exosomes in the treatment of eye diseases -- Transplantation and alternatives to treat autoimmune diseases -- Therapeutic Applications of Mesenchymal Stem Cells for Systemic Lupus Erythematosus -- Potential use of stem cells in mood disorders -- Cancer Stem Cells in Metastasis Therapy -- Regenerative Medicine Applications of Mesenchymal Stem Cells -- stem cells application in thoracic surgery: current perspective and future directions. . |
Record Nr. | UNINA-9910298394803321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cell Biology and Translational Medicine, Volume 3 [[electronic resource] ] : Stem Cells, Bio-materials and Tissue Engineering / / edited by Kursad Turksen |
Edizione | [1st ed. 2018.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
Descrizione fisica | 1 online resource (209 pages) : illustrations |
Disciplina | 616.02774 |
Collana | Cell Biology and Translational Medicine |
Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Gene therapy Genetic engineering Stem Cells Regenerative Medicine/Tissue Engineering Gene Therapy Genetic Engineering |
ISBN | 3-030-04185-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Definitive erythropoiesis from pluripotent stem cells: Recent advances and perspectives -- Comparison of Hematopoietic and Spermatogonial Stem Cell Niches from the Regenerative Medicine Aspect -- Dental stem cells and tooth regeneration -- Challenges in bio-fabrication of organoid cultures -- Bioengineered Scaffolds for Stem Cell Applications in Tissue Engineering and Regenerative Medicine -- Mesenchymal Stem cells and Calcium phosphate bioceramics: Implications in periodontal bone regeneration -- Dental Stem Cells in Bone Tissue Engineering: Current Overview and Challenges -- Graphene based materials in neural tissue regeneration -- Tissue Engineered Skin Substitutes -- Biomaterials and Regenerative Medicine in Urology. |
Record Nr. | UNINA-9910298394303321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cell Biology and Translational Medicine, Volume 4 [[electronic resource] ] : Stem Cells and Cell Based Strategies in Regeneration / / edited by Kursad Turksen |
Edizione | [1st ed. 2018.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
Descrizione fisica | 1 online resource (viii, 191 pages) : illustrations |
Disciplina | 610.28 |
Collana | Cell Biology and Translational Medicine |
Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Gene therapy Genetic engineering Stem Cells Regenerative Medicine/Tissue Engineering Gene Therapy Genetic Engineering |
ISBN | 3-030-10486-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Biomaterials for Regenerative Medicine: Historical Perspectives and Current Trends -- The Great Harmony in Translational Medicine: Biomaterials and Stem Cells -- Adult Stem Cell-based Strategies for Peripheral Nerve Regeneration -- Immunomodulatory Behavior of Mesenchymal Stem Cells -- Gene Therapy Strategies in Bone Tissue Engineering and Current Clinical Applications -- Promotion of cell-based therapy: special focus on the cooperation of mesenchymal stem cell therapy and gene therapy for clinical trial studies -- Mesenchymal Stem Cells-Derived Exosomes for Wound Regeneration Adipose tissue-derived stromal cells for wound healing -- Selection of Suitable Reference Genes for Quantitative Real-Time PCR Normalization in Human Stem Cell Research -- Induced Pluripotent Stem Cells and Induced Pluripotent Cancer Cells in Cancer Disease Modeling. |
Record Nr. | UNINA-9910309665003321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cell Biology and Translational Medicine, Volume 5 [[electronic resource] ] : Stem Cells: Translational Science to Therapy / / edited by Kursad Turksen |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (179 pages) |
Disciplina | 616.02774 |
Collana | Cell Biology and Translational Medicine |
Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Gene therapy Genetic engineering Stem Cells Regenerative Medicine/Tissue Engineering Gene Therapy Genetic Engineering |
ISBN | 3-030-17589-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Therapeutic Cardiac Patches for Repairing the Myocardium -- Human Induced Pluripotent Stem Cells in the Curative Treatment of Diabetes and Potential Impediments Ahead -- CRISPR/Cas9 for Sickle Cell Disease: Applications, Future possibilities, and Challenges -- Photoresponsive Hydrogels with Photoswitchable Stiffness: Emerging Platforms to Study Temporal Aspects of Mesenchymal Stem Cell Responses to Extracellular Stiffness Regulation -- Cellular complexity at the interface: Challenges in enthesis tissue engineering -- Induced Pluripotent Stem Cells in Disease Modelling and Regeneration -- Stem cells for the oromaxillofacial area: Could they be a promising source for regeneration in dentistry? -- Stem Cells Derived from Dental Tissues -- A Novel Virtue in Stem Cell Research: Exosomes and Their Role in Differentiation -- Mesenchymal Stem Cells as Regulators of Carcinogenesis. |
Record Nr. | UNINA-9910337943603321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cell Biology and Translational Medicine, Volume 6 [[electronic resource] ] : Stem Cells: Their Heterogeneity, Niche and Regenerative Potential / / edited by Kursad Turksen |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
Descrizione fisica | 1 online resource (VIII, 223 p. 1 illus.) |
Disciplina | 616.02774 |
Collana | Cell Biology and Translational Medicine |
Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Gene therapy Genetic engineering Stem Cells Regenerative Medicine/Tissue Engineering Gene Therapy Genetic Engineering |
ISBN | 3-030-32823-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Addressing variability and heterogeneity of induced pluripotent stem cell-derived cardiomyocytes -- Direct Lineage Reprogramming in the CNS -- Induced pluripotent stem cells for regenerative medicine: Quality control based on evaluation of lipid composition -- Decellularized Adipose Tissue: Biochemical composition, in vivo analysis and potential clinical applications -- Decellularization Concept in Regenerative Medicine -- Synovium-derived mesenchymal stem/ stromal cells and their promise for cartilage regeneration -- Skin stem cells, their niche and tissue engineering approach for skin regeneration -- Neurological regulation of the bone marrow niche -- Homeobox genes and homeodomain proteins: new insights into cardiac development, degeneration and regeneration -- Generation of human stem cell-derived pancreatic organoids (POs) for regenerative medicine. |
Record Nr. | UNINA-9910373939503321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cell Biology and Translational Medicine, Volume 7 [[electronic resource] ] : Stem Cells and Therapy: Emerging Approaches / / edited by Kursad Turksen |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
Descrizione fisica | 1 online resource (VIII, 153 p. 30 illus., 27 illus. in color.) |
Disciplina | 616.02774 |
Collana | Cell Biology and Translational Medicine |
Soggetto topico |
Stem cells
Regenerative medicine Tissue engineering Gene therapy Genetic engineering Stem Cells Regenerative Medicine/Tissue Engineering Gene Therapy Genetic Engineering |
ISBN | 3-030-37845-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Application of iPSC to modelling of respiratory diseases -- Gene editing in human pluripotent stem cells: recent advances for clinical therapies -- Vascular wall as source of stem cells able to differentiate into endothelial cells -- Physiological and therapeutic roles of neuropeptide Y on biological functions -- Rho signaling-directed YAP/TAZ regulation encourages 3D spheroid colony formation and boosts plasticity of Parthenogenetic Stem Cells -- Transamniotic Stem Cell Therapy -- Regenerative medicine: Injectable cell-based therapeutics and approved products -- Stem Cell Therapy for Hepatocellular Carcinoma: Future Perspectives -- Potential of tribological properties of metalnanomaterials in biomedical applications -- The impact of the low frequency of the electromagnetic field on human. |
Record Nr. | UNINA-9910380757703321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|