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Veterinary toxicology [[electronic resource] ] : basic and clinical principles / / edited by Ramesh C. Gupta
| Veterinary toxicology [[electronic resource] ] : basic and clinical principles / / edited by Ramesh C. Gupta |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | New York ; ; London, : Elsevier, : Academic Press, 2007 |
| Descrizione fisica | 1 online resource (1233 p.) |
| Disciplina | 636.08959 |
| Altri autori (Persone) | GuptaRamesh C <1949-> (Ramesh Chandra) |
| Soggetto topico |
Veterinary toxicology
Veterinary toxicology - Information resources Poisons - Physiological effect |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-05057-1
9786611050573 0-08-048160-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Veterinary Toxicology; Copyright Page; Contents; Foreword; Preface; List of Contributors; Part 1 General; Chapter 1 Concepts in veterinary toxicology; INTRODUCTION; HISTORICAL PERSPECTIVE; EVOLUTION OF VETERINARY TOXICOLOGY; A FRAMEWORK FOR ACQUIRING INFORMATION; SOURCES OF INFORMATION; SCHEMATIC EXPERIMENTAL DESIGNS; TOXICOLOGICAL DESCRIPTORS; CONCLUSIONS AND SUMMARY; ACKNOWLEDGMENTS; REFERENCES; Chapter 2 Pharmacokinetics and toxicokinetics: fundamentals and applications in toxicology; INTRODUCTION; FUNDAMENTALS OF XENOBIOTIC DISPOSITION; ABSORPTION
NON-ORAL ROUTES AND XENOBIOTIC ABSORPTION INHALATION; SPECIES DIFFERENCES IN ABSORPTION; DISTRIBUTION; METABOLISM AND ELIMINATION; CLASSICAL TOXICOKINETIC MODELS; FUNDAMENTAL NON-COMPARTMENTAL TOXICOKINETIC PARAMETERS; BIOAVAILABILITY; CLASSICAL PLASMA/TISSUE TOXICOKINETICS: APPLICATIONS IN DRUG DISCOVERY AND DRUG DEVELOPMENT; APPLICATIONS OF ADME AND TOXICOKINETICS IN DRUG DISCOVERY AND DEVELOPMENT; SPECIES SELECTION FOR TERATOGENICITY; DOSE SELECTION FOR PRECLINICAL EARLY DOSE RANGE-FINDING TOXICITY STUDIES; DOSE SELECTION FOR REPEATED DOSE TOXICITY STUDIES CARCINOGENICITY BIOASSAY STUDIES IN RODENTS CONCLUSIONS; REFERENCES; Chapter 3 Physiologically based pharmacokinetic modeling; INTRODUCTION; BACKGROUND; MODEL CONSTRUCTION; PARAMETER ESTIMATION AND IDENTIFIABILITY; MODEL VALIDATION; APPLICATIONS; CONCLUSIONS; REFERENCES; Chapter 4 Toxicological testing: in vivo and in vitro models; INTRODUCTION; IN VIVO MODELS IN TOXICITY TESTING; IN VITRO MODELS OF TOXICITY TESTING; GENERAL SUMMARY AND CONCLUSIONS; REFERENCES; Chapter 5 Epidemiology of animal poisonings; INTRODUCTION; DEMOGRAPHICS; DOGS; CATS; OTHER SPECIES; AGENTS INVOLVED SIGNS AND OUTCOMES CONCLUSIONS; REFERENCES; Chapter 6 Chemicals of terrorism; INTRODUCTION; CHLORINE GAS; PHOSGENE; MUSTARD GAS; LEWISITE; PHOSGENE OXIME; CYANIDE AND HYDROGEN CYANIDE; MILITARY NERVE AGENTS; REFERENCES; Chapter 7 Regulatory considerations in veterinary toxicology; INTRODUCTION; SECTION I. FOOD AND DRUG ADMINISTRATION AND THE CENTER FOR VETERINARY MEDICINE; SECTION II. ENVIRONMENTAL PROTECTION AGENCY; SECTION III. US DEPARTMENT OF AGRICULTURE; SECTION IV. DRUG ENFORCEMENT ADMINISTRATION; SECTION V. OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION SECTION VI. STATUTES, REGULATIONS, AND GUIDELINES REFERENCES; Chapter 8 Toxicology and the law; INTRODUCTION; REASONS FOR CONDUCTING TOXICOLOGY ANALYSES; JURISDICTION - WHAT ARE THE RULES IN THIS FIGHT AND WHO DECIDES THE WINNER?; STANDARD OF PROOF - HOW SURE DO I NEED TO BE?; EVIDENCE; ADMISSIBILITY OF EXPERT TESTIMONY; SPECIFIC CAUSATION: THE DIFFERENTIAL DIAGNOSIS; APPLICATION OF DAUBERT IN TOXICOLOGY CASES; SOME QUESTIONS TO CONSIDER WHEN USING LABORATORY RESULTS IN A LEGAL CASE; ACKNOWLEDGMENT; REFERENCES; FURTHER READING; Part 2 Organ Toxicity; Chapter 9 Neurotoxicity; INTRODUCTION STRUCTURAL TOXICOSES |
| Record Nr. | UNINA-9910458615003321 |
| New York ; ; London, : Elsevier, : Academic Press, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Veterinary toxicology [[electronic resource] ] : basic and clinical principles / / edited by Ramesh C. Gupta
| Veterinary toxicology [[electronic resource] ] : basic and clinical principles / / edited by Ramesh C. Gupta |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | New York ; ; London, : Elsevier, : Academic Press, 2007 |
| Descrizione fisica | 1 online resource (1233 p.) |
| Disciplina | 636.08959 |
| Altri autori (Persone) | GuptaRamesh C <1949-> (Ramesh Chandra) |
| Soggetto topico |
Veterinary toxicology
Veterinary toxicology - Information resources Poisons - Physiological effect |
| ISBN |
1-281-05057-1
9786611050573 0-08-048160-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Veterinary Toxicology; Copyright Page; Contents; Foreword; Preface; List of Contributors; Part 1 General; Chapter 1 Concepts in veterinary toxicology; INTRODUCTION; HISTORICAL PERSPECTIVE; EVOLUTION OF VETERINARY TOXICOLOGY; A FRAMEWORK FOR ACQUIRING INFORMATION; SOURCES OF INFORMATION; SCHEMATIC EXPERIMENTAL DESIGNS; TOXICOLOGICAL DESCRIPTORS; CONCLUSIONS AND SUMMARY; ACKNOWLEDGMENTS; REFERENCES; Chapter 2 Pharmacokinetics and toxicokinetics: fundamentals and applications in toxicology; INTRODUCTION; FUNDAMENTALS OF XENOBIOTIC DISPOSITION; ABSORPTION
NON-ORAL ROUTES AND XENOBIOTIC ABSORPTION INHALATION; SPECIES DIFFERENCES IN ABSORPTION; DISTRIBUTION; METABOLISM AND ELIMINATION; CLASSICAL TOXICOKINETIC MODELS; FUNDAMENTAL NON-COMPARTMENTAL TOXICOKINETIC PARAMETERS; BIOAVAILABILITY; CLASSICAL PLASMA/TISSUE TOXICOKINETICS: APPLICATIONS IN DRUG DISCOVERY AND DRUG DEVELOPMENT; APPLICATIONS OF ADME AND TOXICOKINETICS IN DRUG DISCOVERY AND DEVELOPMENT; SPECIES SELECTION FOR TERATOGENICITY; DOSE SELECTION FOR PRECLINICAL EARLY DOSE RANGE-FINDING TOXICITY STUDIES; DOSE SELECTION FOR REPEATED DOSE TOXICITY STUDIES CARCINOGENICITY BIOASSAY STUDIES IN RODENTS CONCLUSIONS; REFERENCES; Chapter 3 Physiologically based pharmacokinetic modeling; INTRODUCTION; BACKGROUND; MODEL CONSTRUCTION; PARAMETER ESTIMATION AND IDENTIFIABILITY; MODEL VALIDATION; APPLICATIONS; CONCLUSIONS; REFERENCES; Chapter 4 Toxicological testing: in vivo and in vitro models; INTRODUCTION; IN VIVO MODELS IN TOXICITY TESTING; IN VITRO MODELS OF TOXICITY TESTING; GENERAL SUMMARY AND CONCLUSIONS; REFERENCES; Chapter 5 Epidemiology of animal poisonings; INTRODUCTION; DEMOGRAPHICS; DOGS; CATS; OTHER SPECIES; AGENTS INVOLVED SIGNS AND OUTCOMES CONCLUSIONS; REFERENCES; Chapter 6 Chemicals of terrorism; INTRODUCTION; CHLORINE GAS; PHOSGENE; MUSTARD GAS; LEWISITE; PHOSGENE OXIME; CYANIDE AND HYDROGEN CYANIDE; MILITARY NERVE AGENTS; REFERENCES; Chapter 7 Regulatory considerations in veterinary toxicology; INTRODUCTION; SECTION I. FOOD AND DRUG ADMINISTRATION AND THE CENTER FOR VETERINARY MEDICINE; SECTION II. ENVIRONMENTAL PROTECTION AGENCY; SECTION III. US DEPARTMENT OF AGRICULTURE; SECTION IV. DRUG ENFORCEMENT ADMINISTRATION; SECTION V. OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION SECTION VI. STATUTES, REGULATIONS, AND GUIDELINES REFERENCES; Chapter 8 Toxicology and the law; INTRODUCTION; REASONS FOR CONDUCTING TOXICOLOGY ANALYSES; JURISDICTION - WHAT ARE THE RULES IN THIS FIGHT AND WHO DECIDES THE WINNER?; STANDARD OF PROOF - HOW SURE DO I NEED TO BE?; EVIDENCE; ADMISSIBILITY OF EXPERT TESTIMONY; SPECIFIC CAUSATION: THE DIFFERENTIAL DIAGNOSIS; APPLICATION OF DAUBERT IN TOXICOLOGY CASES; SOME QUESTIONS TO CONSIDER WHEN USING LABORATORY RESULTS IN A LEGAL CASE; ACKNOWLEDGMENT; REFERENCES; FURTHER READING; Part 2 Organ Toxicity; Chapter 9 Neurotoxicity; INTRODUCTION STRUCTURAL TOXICOSES |
| Record Nr. | UNINA-9910784652703321 |
| New York ; ; London, : Elsevier, : Academic Press, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Veterinary toxicology [[electronic resource] ] : basic and clinical principles / / edited by Ramesh C. Gupta
| Veterinary toxicology [[electronic resource] ] : basic and clinical principles / / edited by Ramesh C. Gupta |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | New York ; ; London, : Elsevier, : Academic Press, 2007 |
| Descrizione fisica | 1 online resource (1233 p.) |
| Disciplina | 636.08959 |
| Altri autori (Persone) | GuptaRamesh C <1949-> (Ramesh Chandra) |
| Soggetto topico |
Veterinary toxicology
Veterinary toxicology - Information resources Poisons - Physiological effect |
| ISBN |
1-281-05057-1
9786611050573 0-08-048160-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Veterinary Toxicology; Copyright Page; Contents; Foreword; Preface; List of Contributors; Part 1 General; Chapter 1 Concepts in veterinary toxicology; INTRODUCTION; HISTORICAL PERSPECTIVE; EVOLUTION OF VETERINARY TOXICOLOGY; A FRAMEWORK FOR ACQUIRING INFORMATION; SOURCES OF INFORMATION; SCHEMATIC EXPERIMENTAL DESIGNS; TOXICOLOGICAL DESCRIPTORS; CONCLUSIONS AND SUMMARY; ACKNOWLEDGMENTS; REFERENCES; Chapter 2 Pharmacokinetics and toxicokinetics: fundamentals and applications in toxicology; INTRODUCTION; FUNDAMENTALS OF XENOBIOTIC DISPOSITION; ABSORPTION
NON-ORAL ROUTES AND XENOBIOTIC ABSORPTION INHALATION; SPECIES DIFFERENCES IN ABSORPTION; DISTRIBUTION; METABOLISM AND ELIMINATION; CLASSICAL TOXICOKINETIC MODELS; FUNDAMENTAL NON-COMPARTMENTAL TOXICOKINETIC PARAMETERS; BIOAVAILABILITY; CLASSICAL PLASMA/TISSUE TOXICOKINETICS: APPLICATIONS IN DRUG DISCOVERY AND DRUG DEVELOPMENT; APPLICATIONS OF ADME AND TOXICOKINETICS IN DRUG DISCOVERY AND DEVELOPMENT; SPECIES SELECTION FOR TERATOGENICITY; DOSE SELECTION FOR PRECLINICAL EARLY DOSE RANGE-FINDING TOXICITY STUDIES; DOSE SELECTION FOR REPEATED DOSE TOXICITY STUDIES CARCINOGENICITY BIOASSAY STUDIES IN RODENTS CONCLUSIONS; REFERENCES; Chapter 3 Physiologically based pharmacokinetic modeling; INTRODUCTION; BACKGROUND; MODEL CONSTRUCTION; PARAMETER ESTIMATION AND IDENTIFIABILITY; MODEL VALIDATION; APPLICATIONS; CONCLUSIONS; REFERENCES; Chapter 4 Toxicological testing: in vivo and in vitro models; INTRODUCTION; IN VIVO MODELS IN TOXICITY TESTING; IN VITRO MODELS OF TOXICITY TESTING; GENERAL SUMMARY AND CONCLUSIONS; REFERENCES; Chapter 5 Epidemiology of animal poisonings; INTRODUCTION; DEMOGRAPHICS; DOGS; CATS; OTHER SPECIES; AGENTS INVOLVED SIGNS AND OUTCOMES CONCLUSIONS; REFERENCES; Chapter 6 Chemicals of terrorism; INTRODUCTION; CHLORINE GAS; PHOSGENE; MUSTARD GAS; LEWISITE; PHOSGENE OXIME; CYANIDE AND HYDROGEN CYANIDE; MILITARY NERVE AGENTS; REFERENCES; Chapter 7 Regulatory considerations in veterinary toxicology; INTRODUCTION; SECTION I. FOOD AND DRUG ADMINISTRATION AND THE CENTER FOR VETERINARY MEDICINE; SECTION II. ENVIRONMENTAL PROTECTION AGENCY; SECTION III. US DEPARTMENT OF AGRICULTURE; SECTION IV. DRUG ENFORCEMENT ADMINISTRATION; SECTION V. OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION SECTION VI. STATUTES, REGULATIONS, AND GUIDELINES REFERENCES; Chapter 8 Toxicology and the law; INTRODUCTION; REASONS FOR CONDUCTING TOXICOLOGY ANALYSES; JURISDICTION - WHAT ARE THE RULES IN THIS FIGHT AND WHO DECIDES THE WINNER?; STANDARD OF PROOF - HOW SURE DO I NEED TO BE?; EVIDENCE; ADMISSIBILITY OF EXPERT TESTIMONY; SPECIFIC CAUSATION: THE DIFFERENTIAL DIAGNOSIS; APPLICATION OF DAUBERT IN TOXICOLOGY CASES; SOME QUESTIONS TO CONSIDER WHEN USING LABORATORY RESULTS IN A LEGAL CASE; ACKNOWLEDGMENT; REFERENCES; FURTHER READING; Part 2 Organ Toxicity; Chapter 9 Neurotoxicity; INTRODUCTION STRUCTURAL TOXICOSES |
| Record Nr. | UNINA-9910820441303321 |
| New York ; ; London, : Elsevier, : Academic Press, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
