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Fatty acids and lipotoxicity in obesity and diabetes [[electronic resource] /] / editors: Gregory Bock and Jamie Goode
| Fatty acids and lipotoxicity in obesity and diabetes [[electronic resource] /] / editors: Gregory Bock and Jamie Goode |
| Pubbl/distr/stampa | London, : John Wiley, 2007 |
| Descrizione fisica | 1 online resource (223 p.) |
| Disciplina | 612.397 |
| Altri autori (Persone) |
BockGregory
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Lipids - Metabolism
Fatty acids Adipose tissues Obesity Diabetes |
| ISBN |
1-282-12387-4
9786612123870 0-470-98557-7 0-470-98556-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
FATTY ACIDS AND LIPOTOXICITY IN OBESITY AND DIABETES; Contents; Chair's introduction; Transcriptional control of energy homeostasis through the PGC1 coactivators; DISCUSSION; Human obesity and insulin resistance: lessons from experiments of nature; DISCUSSION; Lipid-induced metabolic dysfunction in skeletal muscle; DISCUSSION; Stearoyl-CoA desaturase deficiency, hypercholesterolaemia, cholestasis and diabetes; DISCUSSION; The role of lipin 1 in adipogenesis and lipid metabolism; DISCUSSION; The role of the AMP-activated protein kinase in the regulation of energy homeostasis; DISCUSSION
Endoplasmic reticulum stress and inflammation in obesity and type 2 diabetesDISCUSSION; The impact of insulin resistance on macrophage death pathways in advanced atherosclerosis; DISCUSSION; Fatty acid transport in adipocytes and the development of insulin resistance; DISCUSSION; Vectorial acylation: linking fatty acid transport and activation to metabolic trafficking; DISCUSSION; Lipid storage and mobilization pathways in yeast; DISCUSSION; Cide proteins and the development of obesity; DISCUSSION; General discussion I; Visualizing brown adipose tissue with FDG-PET Adiponectin and adiponectin receptors in obesity-linked insulin resistanceDISCUSSION; Anti-inflammatory and antidiabetic roles of PPARy; DISCUSSION; Final Discussion; Nutrition, ageing and lipotoxicity; Contributor Index; Subject Index |
| Record Nr. | UNINA-9910840848503321 |
| London, : John Wiley, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
From genome to therapy : integrating new technologies with drug development
| From genome to therapy : integrating new technologies with drug development |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | [Place of publication not identified], : John Wiley, 2000 |
| Descrizione fisica | 1 online resource (173 pages) |
| Disciplina | 615/.19 |
| Collana | Novartis Foundation symposium From genome to therapy |
| Soggetto topico |
Pharmacogenomics
Pharmacogenetics Pharmacology Computational Biology Drug Discovery Genetics Investigative Techniques Biology Biological Science Disciplines Health Occupations Chemistry, Pharmaceutical Natural Science Disciplines Disciplines and Occupations Chemistry Analytical, Diagnostic and Therapeutic Techniques and Equipment Drug Design Genomics Health & Biological Sciences Pharmacy, Therapeutics, & Pharmacology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-55549-1
9786610555499 0-470-85183-X 0-470-84664-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910143509003321 |
| [Place of publication not identified], : John Wiley, 2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
From genome to therapy : integrating new technologies with drug development
| From genome to therapy : integrating new technologies with drug development |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | [Place of publication not identified], : John Wiley, 2000 |
| Descrizione fisica | 1 online resource (173 pages) |
| Disciplina | 615/.19 |
| Collana | Novartis Foundation symposium From genome to therapy |
| Soggetto topico |
Pharmacogenomics
Pharmacogenetics Pharmacology Computational Biology Drug Discovery Genetics Investigative Techniques Biology Biological Science Disciplines Health Occupations Chemistry, Pharmaceutical Natural Science Disciplines Disciplines and Occupations Chemistry Analytical, Diagnostic and Therapeutic Techniques and Equipment Drug Design Genomics Health & Biological Sciences Pharmacy, Therapeutics, & Pharmacology |
| ISBN |
1-280-55549-1
9786610555499 0-470-85183-X 0-470-84664-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910831047903321 |
| [Place of publication not identified], : John Wiley, 2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
From genome to therapy : integrating new technologies with drug development
| From genome to therapy : integrating new technologies with drug development |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | [Place of publication not identified], : John Wiley, 2000 |
| Descrizione fisica | 1 online resource (173 pages) |
| Disciplina | 615/.19 |
| Collana | Novartis Foundation symposium From genome to therapy |
| Soggetto topico |
Pharmacogenomics
Pharmacogenetics Pharmacology Computational Biology Drug Discovery Genetics Investigative Techniques Biology Biological Science Disciplines Health Occupations Chemistry, Pharmaceutical Natural Science Disciplines Disciplines and Occupations Chemistry Analytical, Diagnostic and Therapeutic Techniques and Equipment Drug Design Genomics Health & Biological Sciences Pharmacy, Therapeutics, & Pharmacology |
| ISBN |
1-280-55549-1
9786610555499 0-470-85183-X 0-470-84664-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910841317503321 |
| [Place of publication not identified], : John Wiley, 2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Gastroenteritis viruses / / [editors: Derek Chadwich (Organizer) and Jamie A. Goode] [[electronic resource]]
| Gastroenteritis viruses / / [editors: Derek Chadwich (Organizer) and Jamie A. Goode] [[electronic resource]] |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 2001 |
| Descrizione fisica | 1 online resource (ix, 323 p. ) : ill. ; |
| Disciplina | 616.3/30194 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana |
Novartis Foundation Symposia
Novartis Foundation symposium |
| Soggetto topico |
Gastroenteritis
Viral diarrhea Virus diseases Gastroenteritis - virology Rotavirus Infections - virology |
| Soggetto genere / forma |
Congress.
Computer network resources. Electronic books |
| ISBN |
0-470-84653-4
9786610555437 1-280-55543-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910142451403321 |
| Chichester ; ; New York, : Wiley, 2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Gastroenteritis viruses / / [editors: Derek Chadwich (Organizer) and Jamie A. Goode] [[electronic resource]]
| Gastroenteritis viruses / / [editors: Derek Chadwich (Organizer) and Jamie A. Goode] [[electronic resource]] |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 2001 |
| Descrizione fisica | 1 online resource (ix, 323 p. ) : ill. ; |
| Disciplina | 616.3/30194 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana |
Novartis Foundation Symposia
Novartis Foundation symposium |
| Soggetto topico |
Gastroenteritis
Viral diarrhea Virus diseases Gastroenteritis - virology Rotavirus Infections - virology |
| Soggetto genere / forma |
Congress.
Computer network resources. |
| ISBN |
0-470-84653-4
9786610555437 1-280-55543-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910830180403321 |
| Chichester ; ; New York, : Wiley, 2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Gastroenteritis viruses / / [editors: Derek Chadwich (Organizer) and Jamie A. Goode] [[electronic resource]]
| Gastroenteritis viruses / / [editors: Derek Chadwich (Organizer) and Jamie A. Goode] [[electronic resource]] |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 2001 |
| Descrizione fisica | 1 online resource (ix, 323 p. ) : ill. ; |
| Disciplina | 616.3/30194 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana |
Novartis Foundation Symposia
Novartis Foundation symposium |
| Soggetto topico |
Gastroenteritis
Viral diarrhea Virus diseases Gastroenteritis - virology Rotavirus Infections - virology |
| Soggetto genere / forma |
Congress.
Computer network resources. |
| ISBN |
0-470-84653-4
9786610555437 1-280-55543-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910841752903321 |
| Chichester ; ; New York, : Wiley, 2001 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Generation and effector functions of regulatory lymphocytes [[electronic resource] /] / [editors, Gregory Bock and Jamie Goode]
| Generation and effector functions of regulatory lymphocytes [[electronic resource] /] / [editors, Gregory Bock and Jamie Goode] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2003 |
| Descrizione fisica | 1 online resource (327 p.) |
| Disciplina | 571.96 |
| Altri autori (Persone) |
BockGregory
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Lymphocytes
T cells Immune response - Regulation |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-27406-9
9786610274062 0-470-87161-X 0-470-87162-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GENERATION AND EFFECTOR FUNCTIONS OF REGULATORY LYMPHOCYTES; Contents; Participants; Chair's introduction; Thymic generation and selection of CD25(+)CD4(+) regulatory T cells: implications of their broad repertoire and high self-reactivity for the maintenance of immunological self-tolerance; Discussion; Control of T cell activation by CD4(+)CD25(+) suppressor T cells; Discussion; Regulation of experimental autoimmune encephalomyelitis (EAE) by CD4(+)CD25(+) regulatory T cells; Discussion; The role of CD28 and CTLA4 in the function and homeostasis of CD4(+)CD25(+) regulatory T cells
DiscussionCD4(+)CD25(+) regulatory cells from human peripheral blood express very high levels of CD25 ex vivo; Discussion; Control of immune pathology by regulatory T cells; Discussion; General discussion I TGFB; Type 1 T regulatory cells and their relationship with CD4(+)CD25(+) T regulatory cells; Discussion; (PRO)insulin-specific regulatory T cells; Discussion; CD1d-restricted NKT regulatory cells: functional genomic analyses provide new insights into the mechanisms of protection against Type 1 diabetes; Discussion Seven surprises in the TCR-centred regulation of immune responsiveness in an autoimmune systemDiscussion; Regulatory cells in transplantation; Discussion; CD4(+) regulatory T cells in chronic viral infection; Discussion; General discussion II; Modulation of T cell responses after cross-talk between antigen presenting cells and T cells: a give-and-take relationship; Discussion; Dendritic cells: controllers of the immune system and a new promise for immunotherapy; Discussion; Regulation of viral and autoimmune responses; Discussion; General discussion III Active immune regulation Notch signalling in the peripheral immune systemDiscussion; CD3 antibody treatment stimulates the functional capability of regulatory T cells; Discussion; The role of dendritic cells in regulating mucosal immunity and tolerance; Discussion; Index of contributors; Subject index |
| Record Nr. | UNINA-9910143227103321 |
| Hoboken, N.J., : Wiley, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Generation and effector functions of regulatory lymphocytes [[electronic resource] /] / [editors, Gregory Bock and Jamie Goode]
| Generation and effector functions of regulatory lymphocytes [[electronic resource] /] / [editors, Gregory Bock and Jamie Goode] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2003 |
| Descrizione fisica | 1 online resource (327 p.) |
| Disciplina | 571.96 |
| Altri autori (Persone) |
BockGregory
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Lymphocytes
T cells Immune response - Regulation |
| ISBN |
1-280-27406-9
9786610274062 0-470-87161-X 0-470-87162-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GENERATION AND EFFECTOR FUNCTIONS OF REGULATORY LYMPHOCYTES; Contents; Participants; Chair's introduction; Thymic generation and selection of CD25(+)CD4(+) regulatory T cells: implications of their broad repertoire and high self-reactivity for the maintenance of immunological self-tolerance; Discussion; Control of T cell activation by CD4(+)CD25(+) suppressor T cells; Discussion; Regulation of experimental autoimmune encephalomyelitis (EAE) by CD4(+)CD25(+) regulatory T cells; Discussion; The role of CD28 and CTLA4 in the function and homeostasis of CD4(+)CD25(+) regulatory T cells
DiscussionCD4(+)CD25(+) regulatory cells from human peripheral blood express very high levels of CD25 ex vivo; Discussion; Control of immune pathology by regulatory T cells; Discussion; General discussion I TGFB; Type 1 T regulatory cells and their relationship with CD4(+)CD25(+) T regulatory cells; Discussion; (PRO)insulin-specific regulatory T cells; Discussion; CD1d-restricted NKT regulatory cells: functional genomic analyses provide new insights into the mechanisms of protection against Type 1 diabetes; Discussion Seven surprises in the TCR-centred regulation of immune responsiveness in an autoimmune systemDiscussion; Regulatory cells in transplantation; Discussion; CD4(+) regulatory T cells in chronic viral infection; Discussion; General discussion II; Modulation of T cell responses after cross-talk between antigen presenting cells and T cells: a give-and-take relationship; Discussion; Dendritic cells: controllers of the immune system and a new promise for immunotherapy; Discussion; Regulation of viral and autoimmune responses; Discussion; General discussion III Active immune regulation Notch signalling in the peripheral immune systemDiscussion; CD3 antibody treatment stimulates the functional capability of regulatory T cells; Discussion; The role of dendritic cells in regulating mucosal immunity and tolerance; Discussion; Index of contributors; Subject index |
| Record Nr. | UNINA-9910830549003321 |
| Hoboken, N.J., : Wiley, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Generation and effector functions of regulatory lymphocytes [[electronic resource] /] / [editors, Gregory Bock and Jamie Goode]
| Generation and effector functions of regulatory lymphocytes [[electronic resource] /] / [editors, Gregory Bock and Jamie Goode] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2003 |
| Descrizione fisica | 1 online resource (327 p.) |
| Disciplina | 571.96 |
| Altri autori (Persone) |
BockGregory
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Lymphocytes
T cells Immune response - Regulation |
| ISBN |
1-280-27406-9
9786610274062 0-470-87161-X 0-470-87162-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GENERATION AND EFFECTOR FUNCTIONS OF REGULATORY LYMPHOCYTES; Contents; Participants; Chair's introduction; Thymic generation and selection of CD25(+)CD4(+) regulatory T cells: implications of their broad repertoire and high self-reactivity for the maintenance of immunological self-tolerance; Discussion; Control of T cell activation by CD4(+)CD25(+) suppressor T cells; Discussion; Regulation of experimental autoimmune encephalomyelitis (EAE) by CD4(+)CD25(+) regulatory T cells; Discussion; The role of CD28 and CTLA4 in the function and homeostasis of CD4(+)CD25(+) regulatory T cells
DiscussionCD4(+)CD25(+) regulatory cells from human peripheral blood express very high levels of CD25 ex vivo; Discussion; Control of immune pathology by regulatory T cells; Discussion; General discussion I TGFB; Type 1 T regulatory cells and their relationship with CD4(+)CD25(+) T regulatory cells; Discussion; (PRO)insulin-specific regulatory T cells; Discussion; CD1d-restricted NKT regulatory cells: functional genomic analyses provide new insights into the mechanisms of protection against Type 1 diabetes; Discussion Seven surprises in the TCR-centred regulation of immune responsiveness in an autoimmune systemDiscussion; Regulatory cells in transplantation; Discussion; CD4(+) regulatory T cells in chronic viral infection; Discussion; General discussion II; Modulation of T cell responses after cross-talk between antigen presenting cells and T cells: a give-and-take relationship; Discussion; Dendritic cells: controllers of the immune system and a new promise for immunotherapy; Discussion; Regulation of viral and autoimmune responses; Discussion; General discussion III Active immune regulation Notch signalling in the peripheral immune systemDiscussion; CD3 antibody treatment stimulates the functional capability of regulatory T cells; Discussion; The role of dendritic cells in regulating mucosal immunity and tolerance; Discussion; Index of contributors; Subject index |
| Record Nr. | UNINA-9910841063903321 |
| Hoboken, N.J., : Wiley, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
