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Phospholipases in Health and Disease / / edited by Paramjit S. Tappia, Naranjan S. Dhalla
| Phospholipases in Health and Disease / / edited by Paramjit S. Tappia, Naranjan S. Dhalla |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (416 p.) |
| Disciplina | 571.64 |
| Collana | Advances in Biochemistry in Health and Disease |
| Soggetto topico |
Lipids
Medicine - Research Biology - Research Enzymology Proteins Neurosciences Biological transport Cell membranes Lipidology Biomedical Research Neuroscience Membrane Trafficking |
| ISBN | 1-4939-0464-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Phospholipases in Health and Disease -- Role of Phospholipases in Regulation of Cardiolipin Biosynthesis and Remodelling in the Heart and Mammalian Cells -- Role of Phospholipases and Oxidized Phospholipids in Inflammation -- Phospholipases in Cardiovascular Disease -- The Structures and Functions of Intracellular Phospholipase A1 Family Proteins -- Phospholipase A and Breast Cancer -- Pathophysiological Aspects of Lipoprotein Associated Phospholipase A2: A Brief Overview -- Phospholipase A2 Activity Exhibited by a Bacterial Virulence Protein that Enters and Operates within a Variety of Host Cells -- Expression and Role of Phospholipase A2 in Central Nervous System Injury and Disease -- Cytoplasmic Phospholipase A2 and Autotaxin Inhibitors as Potential Radiosensitizers -- Phospholipase A2 Enzymes: Potential Targets for Therapy -- The Role of Phospholipase C Isozymes in Cellular Homeostasis -- Phospholipase C in the Immune Cell -- Phosphoinositide-specific Phospholipase C Enzymes and Cognitive Development and Decline -- Where life begins: Sperm PLCz in mammalian egg activation and implications in male infertility -- Oocyte Activation and Phospholipase C zeta (PLCζ): Male Infertility and Implications for Therapeutic Intervention -- Phospholipase C Signaling in Heart Disease -- Activation of Phospholipase C in Cardiac Hypertrophy -- The Protective Effect of Phospholipase C From Cardiac Ischemia-Reperfusion Injury -- Role of Phospholipase C in Cardioprotection During Oxidative Stress -- Mammalian Phospholipase D: Structure, Regulation and Physiological Functions of Phospholipase D and its Link to Pathology -- Emerging Roles of Phospholipase D in Pathophysiological Signaling -- Alterations in Phospholipase D During the Development of Myocardial Disease. |
| Record Nr. | UNINA-9910298337603321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Proteases in Health and Disease / / edited by Sajal Chakraborti, Naranjan S. Dhalla
| Proteases in Health and Disease / / edited by Sajal Chakraborti, Naranjan S. Dhalla |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (407 p.) |
| Disciplina | 572.76 |
| Collana | Advances in Biochemistry in Health and Disease |
| Soggetto topico |
Biochemistry
Cell biology Cell physiology Proteomics Biochemistry, general Cell Biology Cell Physiology |
| ISBN | 1-4614-9233-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part A: Molecular and Biochemical Aspects of Proteases -- 1. An Overview of Endoplasmic Reticulum Calpain System -- 2. Mitochondrial Calpains: Who, What, Where, When and Why? -- 3. Role of Calpains in Calmodulin Regulated Systems -- 4. Exercise and Matrix Metalloproteases: A Brief Overview -- 5. Regulation of Chondrocyte Matrix Metalloproteinase Gene Expression -- 6. Microbial Source of Fibrinolytic Protease and Its Biotechnological Potential -- 7. Aspartic Proteolytic Inhibitors Induce Cellular and Biochemical Alterations in Fungal Cells -- 8. Cysteine Proteases of Human Malaria Parasites -- 9. Proteases as Virulence Factors in Leishmania: Focus on Serine Proteases as Possible Therapeutic Targets -- 10. An Updated Inventory on Properties, Pathophysiology and Therapeutic Potential of Snake Venom Thrombin-like Proteases -- 11. Macrocyclic Protease Inhibitors Constrained into a β-Strand Geometry -- Part B: Involvement of Proteases in Disease Processes -- 12. Regulation of MT1-MMP Activation and Its Relevance to Disease Processes -- 13. Role of Proteases During Intra-erythrocytic Developmental Cycle of Human Malaria Parasite Plasmodium falciparum -- 14. Proteases in Vibrio cholerae and Their Role in Pathogenesis -- 15. ADAMTS13: The von Willebrand Factor Cleaving Protease and Its Role in Thrombotic Thrombocytopenic Purpura -- 16. Role of Proteases and Their Tissue Inhibitors in Pregnancy Outcome -- 17. Matrix Metalloproteinases in Bone Health and Disease -- 18. Escalated Expression of Matrix Metalloproteinases in Osteoarthritis -- 19. Role of Proteases in Autism Spectrum Disorder -- 20. Role of Proteases in the Management of Hepatitis C Virus -- 21. Role of Protease in Inflammatory Lung Diseases -- 22. Involvement of Some Proteolytic Enzymes in Cardiac Dysfunction Due to Ischemia-Reperfusion Injury. |
| Record Nr. | UNINA-9910437843203321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Proteases in Human Diseases / / edited by Sajal Chakraborti, Tapati Chakraborti, Naranjan S. Dhalla
| Proteases in Human Diseases / / edited by Sajal Chakraborti, Tapati Chakraborti, Naranjan S. Dhalla |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XVII, 513 p. 63 illus., 52 illus. in color.) |
| Disciplina | 612 |
| Soggetto topico |
Human physiology
Molecular biology Pharmaceutical technology Cancer research Human Physiology Molecular Medicine Pharmaceutical Sciences/Technology Cancer Research |
| ISBN |
9789811031618
9789811031625 (e-book) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Matrix metalloproteases in breast carcinoma, immunohistology and prognosis -- 2. Matrix metalloproteases in parasite infection -- 3. Cysteine cathepsins: In health and rheumatoid arthritis -- 4. Protective role of antiproteases in radiation induced damage -- 5. Role of proteases in the regulation of N-myristoyltransferase -- 6. Proteases in cancer: Potential therapeutic targets -- 7. MMPs in oral squamous cell carcinoma -- 8. Caspase regulatory mechanisms: Implications in pathogenesis and therapeutics -- 9. Physiological and pathological functions of mitochondrial proteases -- 10. Proteases of parasitic helminths: their metabolic role in establishment of infection in the host -- 11. Cysteine proteases of parasitic helminths -- 12. targeting proteases in urine for bladder cancer diagnosis -- 13. Intramembrane cleaving proteases (ICLiPs), particularly the gamma secretase protease and its role in neurodegeneration, cancer and innate immune signalling -- 14. Contribution of matrix metalloproteases in cardiovascular diseases -- 15. OPG/RANKL-protease axis in cardiometabolic diseases -- 16. Proteases and protease inhibitors in male reproduction -- 17. The role of MMP-2 and -9 in embryonic neural crest cells and their derivatives -- 18. Proteolytic ubiquitin like proteins -- 19. C.albicans aspartic proteases: role of these enzymes in degradation of crucial human host proteins at the place of infection and a possible implications of the protease action for propagation of infection. -- 20. MMPs in cancer -- 21. Pathophysiological roles played by proteases of Psedomonas aeruginosa: crucial multifunctional molecules involved in the host infection -- 22. Role of proteases on activating cell death pathways -- 23. varying faces of matrix metalloproteinases in cardiovascular diseases -- 24. kallikreins and kallikrein related peptides (KLKs) in health and disease -- 25. Endogenous proteases in tumoral progression. |
| Record Nr. | UNINA-9910253924403321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Proteases in Physiology and Pathology / / edited by Sajal Chakraborti, Naranjan S. Dhalla
| Proteases in Physiology and Pathology / / edited by Sajal Chakraborti, Naranjan S. Dhalla |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XV, 619 p. 97 illus., 78 illus. in color.) |
| Disciplina | 612 |
| Soggetto topico |
Human physiology
Molecular biology Pharmaceutical technology Cancer research Human Physiology Molecular Medicine Pharmaceutical Sciences/Technology Cancer Research |
| ISBN | 981-10-2513-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Physiological and Pathological Functions of Mitochondrial Proteases -- The Role of MMP2 and 9 in Embryonic Neural Crest Cells and their Derivatives -- The matrix metalloproteinase and tissue inhibitors of metalloproteinase balance in physiologicaland pathological remodeling of skeletal muscles -- Role of BMP1/ tolloid like proteases in bone morphogenesis and tissue remodeling -- Role of proteases in the regulation of N-myristoyltransferase -- Role of Tissue Factor-FVIIa Blood Coagulation Initiation complex in Cancer -- Metalloproteases in adaptive cell responses -- Proteases from protozoa and their role in infection.-Regulation of Extracellular Matrix Remodeling and Epithelial-Mesenchymal Transition by Matrix Metalloproteinases: Decisive Candidates in Tumor Progression.- Proteases and Protease Inhibitors in Male Reproduction -- Physiological and Pathological Functions of Cysteine Cathepsins -- Role of serine proteases and inhibitors in cancer -- Role of Proteases in diabetes and diabetic complications.- Plant Latex Proteases: Natural Wound Healers -- Emerging Role of Mitochondrial Serine Protease HtrA2 in Neurodegeneration -- Functional Relevance of Deubiquitinases in Life and Disease -- Sub-Mitochondrial Calpains in Pathophysiological Consequences.- Serine Proteases in the Lectin Pathway of the Complement System.- Pups, SAMPs and Prokaryotic Proteasomes.- Role of Proteases in Photoaging of Skin.- Insect proteases: Structural-functional outlook.- Protease-antiprotease interactions: an overview of the process from an in silico perspective -- Snake venom proteases as toxins and tools.- The world of the proteases across micros, insects and medicinal trees.- Insight into the mode of interactions between bacterial proteases and their substrates.- The Ubiquitin Proteasome System with itsChecks and Balances.- A brief account of structure function relationship of the traditional cysteine protease inhibitor-cystatin with a special focus on human family 1 & 2 cystatins.- Solid Support Synthesis of a Dnp-labeled Peptide for Assay of Matrix Metalloproteinase-2. |
| Record Nr. | UNINA-9910253938703321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Regulation of Ca2+-ATPases,V-ATPases and F-ATPases / / edited by Sajal Chakraborti, Naranjan S Dhalla
| Regulation of Ca2+-ATPases,V-ATPases and F-ATPases / / edited by Sajal Chakraborti, Naranjan S Dhalla |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (582 p.) |
| Disciplina | 570 |
| Collana | Advances in Biochemistry in Health and Disease |
| Soggetto topico |
Proteins
Biological transport Cell membranes Atomic structure Molecular structure Medicine - Research Biology - Research Membrane Trafficking Protein Biochemistry Atomic and Molecular Structure and Properties Biomedical Research |
| ISBN | 3-319-24780-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part A -- 1 Historical Perspectives of Ca2+ ATPase -- 2 The Plasma Membrane Ca2+ATPases: Isoforms Specificity and Functional Versatility -- 3 PMCA2 w/a Splice Variant: A Key Regulator of Hair Cell Mechanotransduction Machinery.- 4 PMCA-3, A Mysterious Isoform of Calcium Pump -- 5 The ATP2B Plasma Membrane Ca2+ ATPase Family: Regulation in Response to Changing Demands of Cellular Calcium Transport -- 6 The Plasma Membrane Ca2+-ATPase and the Na/Ca exchanger in β-cell Function and Diabetes -- 7 Long-range Allosteric Regulation of Pumps and Transporters: What Can We Learn From Mammalian NCX Antiporters? -- 8 Regulation of Ca2+/Mg2+ecto-ATPase in the Heart -- Part B -- 9 The Ca2+-ATPase of the Sarco/endoplasmic Reticulum(SERCA):Structure and Control -- 10 Functional and Structural Insights into Sarcolipin, a Regulator of the Sarco-Endoplasmic Reticulum Ca2+-ATPases -- 11 Regulation of Sarco (endo)plasmic Reticulum Calcium ATPase (SERCA) in Response to Exercise -- 12 Calcium Handling in Pulmonary Vasculature Under Oxidative Stress: Focus on SERCA -- 13 Plant Type 2B Ca2+-ATPases: The Diversity of Isoforms of the Model PlantArabidopsis Thaliana -- 14 Regulation of Ca2+ transport ATPase by Amino-and Carboxy Terminal Extensions: Mechanisms and (Patho)Physiological Implications -- Part A -- 15 Function and Regulation of Mammalian V-ATPase Isoforms -- 16 Eucaryotic V-type ATPase and its Super Complexes: From Structure and Function to Disease and Drug Targeting -- 17 Vacuolar ATPase in Physiology and Pathology: Roles in Neurobiology, Infectious Disease and Cancer -- 18 Vacular H+-ATPase Signaling in Cancer -- 19 V-ATPases and their Implication in Oral Cancer -- 20 The Vacular Proton ATPase (V-ATPase): Regulation and Therapeutic Targeting -- Part D -- 21 Thiol-related Regulation of the Mitochondrial F1Fo-ATPase Activity -- 22 F1Fo-ATPase Functions Under Markedly Acidic Conditions in Bacteria.- 23 Tuning the ATPase Activity of Hsp 90 -- 24 Role of ATPase in Disease Processes -- 25 Renal H+-ATPase Function, Regulation, and Role in Distal Renal Tubular Acidosis -- 26 Plasma Membrane ATPase: Potential Target for Antifungal Drug Therapy -- 27 The Yeast Ca2+-ATPases and Ca2+/H+ Exchangers of the Secretory Pathway and Their Regul ation -- 28 Role of P5A-type ATPase in Ion Homeostasis and Signalling: Shedding Light on obscure Pump. |
| Record Nr. | UNINA-9910253882703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Regulation of Membrane Na+-K+ ATPase / / edited by Sajal Chakraborti, Naranjan S Dhalla
| Regulation of Membrane Na+-K+ ATPase / / edited by Sajal Chakraborti, Naranjan S Dhalla |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (434 p.) |
| Disciplina | 570 |
| Collana | Advances in Biochemistry in Health and Disease |
| Soggetto topico |
Proteins
Biological transport Cell membranes Atomic structure Molecular structure Medicine - Research Biology - Research Membrane Trafficking Protein Biochemistry Atomic and Molecular Structure and Properties Biomedical Research |
| ISBN | 3-319-24750-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part A -- 1 Na+/K+-ATPase: A Perspective -- 2 Na+/K+-ATPase and Its Role in Signal Transduction -- 3 Na+ K+-ATPase Cell Signaling Pathways and Cancer -- 4 Calcium Controls the P2-ATPase Mediated Homeostasis: Essential Role of NaAF -- 5 Na+/K+-ATPase α4: An Isoform Dedicated to Sperm Function -- 6 The Role of the 2nd Na+ Pump in Mammals and Parasites -- 7 Myocardial Na+/K+-ATPase and SERCA: Clinical and Pathological Significance from a Cytological perspective -- 8 Understanding the Dysfunction of Na+/K+-ATPase in Rapid-Onset Dystonia- Parkinsonism and Amyotrophic Lateral Sclerosis -- 9 Activity of Membrane ATPases in Human Erythrocytes Under the Influence of Highly Hydroxylated Fullerenol -- 10 Xenobiotics-mediated Modulation of ATPases and Biomedical Implications -- 11 Emerging Role of Dysadherin in Metastasis -- 12 The Astrocytic Na+/K+-ATPase - Stimulation by Increased Extracellular K+, β-Adrenergic Activation, Ouabain-mediated Signaling, and Interaction with the Transporter NKCC1 -- 13 Uncoupling of P-type ATPases -- 14 Phospholemman: A Brief Overview -- 15 Regulation of the Cardiac Na+/K+-ATPase by Phospholemman -- 16 Regulation of Brain Na+/K+- ATPase Activity by Noradrenaline with Particular Reference to Normal and Altered Rapid Eye Movement Sleep -- 17 Regulation Na+/K+-ATPase Activity in the Nervous System -- 18 Regulation of Membrane Na+/K+ ATPase in Health and Disease -- 19 Redox Regulation of the Na+/K+ ATPase in the Cardiovascular System -- 20 Regulation of Na+/K+-ATPase in Pulmonary Vasculature -- 21 Exercise-induced Regulation of the Na, K-pump in Skeletal Muscles -- 22 Advances in the Understanding of Renal Proximal Tubular Na+/K+-ATPase Regulation by Parathyroid Hormone and Dopamine -- 23 Regulation of Na+/ K+-ATPase in Epithelial-Mesenchymal Transition and Cancer -- 24 Metal Based Compounds, Modulators of Na+/K+-ATPase with Anticancer Activity. |
| Record Nr. | UNINA-9910253874703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Role of Proteases in Cellular Dysfunction / / edited by Naranjan S. Dhalla, Sajal Chakraborti
| Role of Proteases in Cellular Dysfunction / / edited by Naranjan S. Dhalla, Sajal Chakraborti |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (460 p.) |
| Disciplina | 572.4 |
| Collana | Advances in Biochemistry in Health and Disease |
| Soggetto topico |
Proteins
Cytology Cancer Neurosciences Medicine - Research Biology - Research Protein Biochemistry Cell Biology Cancer Biology Neuroscience Biomedical Research |
| ISBN | 1-4614-9099-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part A: Proteases and Neural Disorders.- Role of Calpain in Immunobiology of Neurodegenerative Diseases.- Calpain Interactions with the Protein Phosphatase Calcineurin in Neurodegeneration.- Involvement of Caspases in Neurodegenaration and Stroke.- Matrix Metalloproteinases in Ischemia-Reperfusion Injury in Brain: Antioxidants as Rescuer.- The Role of Matrix Metalloproteinases in Neurovascular Injury.- The Role of Proteases in Embryonic Neural Crest Cells.- Part B: Proteases and Cancer -- Proteases and Cancer Development.- Matrix Metalloproteinase and its Inhibitors in Cancer Progression.- Ubiquitin-Proteosome System in the Hallmarks of Cancer.- Matrix Metalloproteinases in Cancer Metastasis: An unsolved Mystery.- A Disintegrin and Metalloprotease-12 as a New target for Cancer Treatment -- Proteases and Their Role in Drug Development with an Emphasis in Cancer.- Part C: Proteases and Cardiovascular Defects.- Role of Matrix Metalloproteinases in Atherosclerosis.- The Importance of the Urokinase-type Plasminogen Activator (uPA) and its receptor (uPAR) for the Development and Progression of Atherosclerosis.- Matrix Metalloproteinases and Hypertension.- Regulation of Proteolysis in Vascular Remodeling.- Emerging Role of Genetic Variants of Matrix Metalloproteinases Genes in Left Ventricular Dysfunction.- Implications of Intracellular Proteolytic Activation of MMP-2 in the Heart.- Matrix Metalloprotease-2 in the Development and Progression of Cardiovascular Diseases.- Role of Protease Activation in Subcellular Remodeling and Heart Failure.- Proteases as Potential Targets in Left Ventricular Remodeling After Myocardial Infarction.- MMPs in Cardiovascular Diseases: Emerging Pharmacological Targets.- Proteases as Clinical Markers of Adverse Remodeling for Heart Failure in the Aging Population. |
| Record Nr. | UNINA-9910298330103321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
