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The Molecular basis of smell and taste transduction [[electronic resource] /] / [editors, Derek Chadwick, Joan Marsh, and Jamie Goode]
| The Molecular basis of smell and taste transduction [[electronic resource] /] / [editors, Derek Chadwick, Joan Marsh, and Jamie Goode] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 1993 |
| Descrizione fisica | 1 online resource (304 p.) |
| Disciplina |
591.1
591.1826 |
| Altri autori (Persone) |
ChadwickDerek
MarshJoan GoodeJamie |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Smell - Molecular aspects
Taste - Molecular aspects Cellular signal transduction Second messengers (Biochemistry) G proteins |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-34787-X
9786612347870 0-470-51451-5 0-470-51452-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
THE MOLECULAR BASIS OF SMELL AND TASTE TRANSDUCTION; Contents; Participants; Introduction; From genotype to olfactory neuron phenotype: the role of the Olf-I-binding site; Mucous domains: microchemical heterogeneity in the mucociliary complex of the olfactory epithelium; Receptor diversity and spatial patterning in the mammalian olfactory system; Molecular mechanisms of olfactory neuronal gene regulation; A new tool for investigating G protein-coupled receptors; General discussion I; Second messenger signalling in olfaction; Membrane currents and mechanisms of olfactory transduction
Olfactory receptors: transduction, diversity, human psychophysics and genome analysisGeneral discussion II; MolecuIar genetics of Drosophila olfaction; Perireceptor events in taste; Gustducin and transduci n: a tale of two G proteins; Role of apical ion channels in sour taste t ransduction; Ion pathways in the taste bud and their significance for transduction; The cellular and genetic basis of olfactory responses in Caenorhabditis elegans; Genetic and pathological taste variation: what can we learn from animal models and human disease?; General discussion Ill; Summing-up Index of contributorsSubject Index |
| Record Nr. | UNINA-9910144742303321 |
| Chichester ; ; New York, : Wiley, 1993 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The Molecular basis of smell and taste transduction [[electronic resource] /] / [editors, Derek Chadwick, Joan Marsh, and Jamie Goode]
| The Molecular basis of smell and taste transduction [[electronic resource] /] / [editors, Derek Chadwick, Joan Marsh, and Jamie Goode] |
| Pubbl/distr/stampa | Chichester ; ; New York, : Wiley, 1993 |
| Descrizione fisica | 1 online resource (304 p.) |
| Disciplina |
591.1
591.1826 |
| Altri autori (Persone) |
ChadwickDerek
MarshJoan GoodeJamie |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Smell - Molecular aspects
Taste - Molecular aspects Cellular signal transduction Second messengers (Biochemistry) G proteins |
| ISBN |
1-282-34787-X
9786612347870 0-470-51451-5 0-470-51452-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
THE MOLECULAR BASIS OF SMELL AND TASTE TRANSDUCTION; Contents; Participants; Introduction; From genotype to olfactory neuron phenotype: the role of the Olf-I-binding site; Mucous domains: microchemical heterogeneity in the mucociliary complex of the olfactory epithelium; Receptor diversity and spatial patterning in the mammalian olfactory system; Molecular mechanisms of olfactory neuronal gene regulation; A new tool for investigating G protein-coupled receptors; General discussion I; Second messenger signalling in olfaction; Membrane currents and mechanisms of olfactory transduction
Olfactory receptors: transduction, diversity, human psychophysics and genome analysisGeneral discussion II; MolecuIar genetics of Drosophila olfaction; Perireceptor events in taste; Gustducin and transduci n: a tale of two G proteins; Role of apical ion channels in sour taste t ransduction; Ion pathways in the taste bud and their significance for transduction; The cellular and genetic basis of olfactory responses in Caenorhabditis elegans; Genetic and pathological taste variation: what can we learn from animal models and human disease?; General discussion Ill; Summing-up Index of contributorsSubject Index |
| Record Nr. | UNINA-9910677782703321 |
| Chichester ; ; New York, : Wiley, 1993 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The molecular biology and pathology of elastic tissues [[electronic resource] /] / [editors Derek J. Chadwick and Jamie A. Goode]
| The molecular biology and pathology of elastic tissues [[electronic resource] /] / [editors Derek J. Chadwick and Jamie A. Goode] |
| Pubbl/distr/stampa | Chichester ; ; New York, : J. Wiley, 1995 |
| Descrizione fisica | 1 online resource (373 p.) |
| Disciplina |
574.82
611.0182 611/.0182 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Elastin
Elastic tissue - Diseases - Molecular aspects |
| Soggetto genere / forma | Electronic books. |
| Soggetto non controllato | Connective tissues |
| ISBN |
1-282-45539-7
9786612455391 0-470-51477-9 0-470-51478-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
THE MOLECULAR BIOLOGY AND PATHOLOGY OF ELASTIC TISSUES; Contents; Participants; Preface; Chairman's in trod uction; Molecular biophysics of elastin structure, function and pathology; UItrastructure of elastin; General discussion I; Structure of the elastin gene; Regulation of elastin synthesis in pathological states; Catalytic properties and structural components of lysyl oxidase; General discussion II; The structure and function of fibrillin; Elastin gene mutations in transgenic mice; Elastic fibre assembly: macromolecular interactions
The 67 kDa spliced variant of b-galactosidase serves as a reusable protective chaperone for tropoelastinGeneral discussion Ill; Elastin in lung development and disease; Elastin and mechanoreceptor mechanisms with special reference to the mammalian carotid sinus; Skin elastic fibres: regulation of human elastin promoter activity in transgenic mice; Elastin in systemic and pulmonary hypertension; General discussion IV; Elastin in blood vessels; General discussion V; Elastase in the prevention of arterial ageing and the treatment of the rosclerosis Interaction of tumour cells with elastin and the metastatic phenotypeA role for neutrophil elastase in solar elastosis; Closing reflections; Index of contributors; Subject Index |
| Record Nr. | UNINA-9910144011603321 |
| Chichester ; ; New York, : J. Wiley, 1995 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The molecular biology and pathology of elastic tissues [[electronic resource] /] / [editors Derek J. Chadwick and Jamie A. Goode]
| The molecular biology and pathology of elastic tissues [[electronic resource] /] / [editors Derek J. Chadwick and Jamie A. Goode] |
| Pubbl/distr/stampa | Chichester ; ; New York, : J. Wiley, 1995 |
| Descrizione fisica | 1 online resource (373 p.) |
| Disciplina |
574.82
611.0182 611/.0182 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Elastin
Elastic tissue - Diseases - Molecular aspects |
| Soggetto non controllato | Connective tissues |
| ISBN |
1-282-45539-7
9786612455391 0-470-51477-9 0-470-51478-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
THE MOLECULAR BIOLOGY AND PATHOLOGY OF ELASTIC TISSUES; Contents; Participants; Preface; Chairman's in trod uction; Molecular biophysics of elastin structure, function and pathology; UItrastructure of elastin; General discussion I; Structure of the elastin gene; Regulation of elastin synthesis in pathological states; Catalytic properties and structural components of lysyl oxidase; General discussion II; The structure and function of fibrillin; Elastin gene mutations in transgenic mice; Elastic fibre assembly: macromolecular interactions
The 67 kDa spliced variant of b-galactosidase serves as a reusable protective chaperone for tropoelastinGeneral discussion Ill; Elastin in lung development and disease; Elastin and mechanoreceptor mechanisms with special reference to the mammalian carotid sinus; Skin elastic fibres: regulation of human elastin promoter activity in transgenic mice; Elastin in systemic and pulmonary hypertension; General discussion IV; Elastin in blood vessels; General discussion V; Elastase in the prevention of arterial ageing and the treatment of the rosclerosis Interaction of tumour cells with elastin and the metastatic phenotypeA role for neutrophil elastase in solar elastosis; Closing reflections; Index of contributors; Subject Index |
| Record Nr. | UNINA-9910831001103321 |
| Chichester ; ; New York, : J. Wiley, 1995 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The molecular biology and pathology of elastic tissues [[electronic resource] /] / [editors Derek J. Chadwick and Jamie A. Goode]
| The molecular biology and pathology of elastic tissues [[electronic resource] /] / [editors Derek J. Chadwick and Jamie A. Goode] |
| Pubbl/distr/stampa | Chichester ; ; New York, : J. Wiley, 1995 |
| Descrizione fisica | 1 online resource (373 p.) |
| Disciplina |
574.82
611.0182 611/.0182 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Elastin
Elastic tissue - Diseases - Molecular aspects |
| Soggetto non controllato | Connective tissues |
| ISBN |
1-282-45539-7
9786612455391 0-470-51477-9 0-470-51478-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
THE MOLECULAR BIOLOGY AND PATHOLOGY OF ELASTIC TISSUES; Contents; Participants; Preface; Chairman's in trod uction; Molecular biophysics of elastin structure, function and pathology; UItrastructure of elastin; General discussion I; Structure of the elastin gene; Regulation of elastin synthesis in pathological states; Catalytic properties and structural components of lysyl oxidase; General discussion II; The structure and function of fibrillin; Elastin gene mutations in transgenic mice; Elastic fibre assembly: macromolecular interactions
The 67 kDa spliced variant of b-galactosidase serves as a reusable protective chaperone for tropoelastinGeneral discussion Ill; Elastin in lung development and disease; Elastin and mechanoreceptor mechanisms with special reference to the mammalian carotid sinus; Skin elastic fibres: regulation of human elastin promoter activity in transgenic mice; Elastin in systemic and pulmonary hypertension; General discussion IV; Elastin in blood vessels; General discussion V; Elastase in the prevention of arterial ageing and the treatment of the rosclerosis Interaction of tumour cells with elastin and the metastatic phenotypeA role for neutrophil elastase in solar elastosis; Closing reflections; Index of contributors; Subject Index |
| Record Nr. | UNINA-9910841235703321 |
| Chichester ; ; New York, : J. Wiley, 1995 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular clocks and light signalling [[electronic resource] /] / [editors, Derek J. Chadwick and Jamie A. Goode]
| Molecular clocks and light signalling [[electronic resource] /] / [editors, Derek J. Chadwick and Jamie A. Goode] |
| Pubbl/distr/stampa | Chichester, UK ; ; Hoboken, NJ, : Wiley, 2003 |
| Descrizione fisica | 1 online resource (308 p.) |
| Disciplina |
571.4
571.7/7 571.77 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Circadian rhythms
Photobiochemistry |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-26907-3
9786610269075 0-470-09082-0 0-470-09083-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MOLECULAR CLOCKS AND LIGHT SIGNALLING; Contents; Participants; Chair's introduction; Non-rod, non-cone photoreception in rodents and teleost fish; Discussion; Cryptochromes and inner retinal non-visual irradiance detection; Discussion; General discussion I; Light signalling in Cryptochrome-deficient mice; Discussion; Circadian light input in plants, flies, and mammals; Discussion; Orphan nuclear receptors, molecular clockwork, and the entrainment of peripheral oscillators; Discussion; General discussion; SCN: ringmaster of the circadian circus or conductor of the circadian orchestra?
DiscussionOn the communication pathways between the central pacemaker and peripheral oscillators; Discussion; Central and peripheral circadian oscillators in Drosophila; Discussion; Integration of molecular rhythms in mammalian circadian system; Circadian transcriptional output in the SCN and liver of the mouse; Discussion; The molecular workings of the Neurospora biological clock; Discussion; Expression of clock gene products in the suprachiasmatic nucleus in relation to circadian behaviour; Discussion; Circadian rhythms in Drosophila; Discussion The role of phosphorylation and degradation of hPer proteins oscillation in normal human fibroblastsDiscussion; Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signalling; Discussion; CK1 and GSK-3 in the Drosophila and mammalian circadian clock; Discussion; Final general discussion; Closing remarks; Index of contributors; Subject index |
| Record Nr. | UNINA-9910143479603321 |
| Chichester, UK ; ; Hoboken, NJ, : Wiley, 2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular clocks and light signalling [[electronic resource] /] / [editors, Derek J. Chadwick and Jamie A. Goode]
| Molecular clocks and light signalling [[electronic resource] /] / [editors, Derek J. Chadwick and Jamie A. Goode] |
| Pubbl/distr/stampa | Chichester, UK ; ; Hoboken, NJ, : Wiley, 2003 |
| Descrizione fisica | 1 online resource (308 p.) |
| Disciplina |
571.4
571.7/7 571.77 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Circadian rhythms
Photobiochemistry |
| ISBN |
1-280-26907-3
9786610269075 0-470-09082-0 0-470-09083-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MOLECULAR CLOCKS AND LIGHT SIGNALLING; Contents; Participants; Chair's introduction; Non-rod, non-cone photoreception in rodents and teleost fish; Discussion; Cryptochromes and inner retinal non-visual irradiance detection; Discussion; General discussion I; Light signalling in Cryptochrome-deficient mice; Discussion; Circadian light input in plants, flies, and mammals; Discussion; Orphan nuclear receptors, molecular clockwork, and the entrainment of peripheral oscillators; Discussion; General discussion; SCN: ringmaster of the circadian circus or conductor of the circadian orchestra?
DiscussionOn the communication pathways between the central pacemaker and peripheral oscillators; Discussion; Central and peripheral circadian oscillators in Drosophila; Discussion; Integration of molecular rhythms in mammalian circadian system; Circadian transcriptional output in the SCN and liver of the mouse; Discussion; The molecular workings of the Neurospora biological clock; Discussion; Expression of clock gene products in the suprachiasmatic nucleus in relation to circadian behaviour; Discussion; Circadian rhythms in Drosophila; Discussion The role of phosphorylation and degradation of hPer proteins oscillation in normal human fibroblastsDiscussion; Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signalling; Discussion; CK1 and GSK-3 in the Drosophila and mammalian circadian clock; Discussion; Final general discussion; Closing remarks; Index of contributors; Subject index |
| Record Nr. | UNINA-9910830087503321 |
| Chichester, UK ; ; Hoboken, NJ, : Wiley, 2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular clocks and light signalling [[electronic resource] /] / [editors, Derek J. Chadwick and Jamie A. Goode]
| Molecular clocks and light signalling [[electronic resource] /] / [editors, Derek J. Chadwick and Jamie A. Goode] |
| Pubbl/distr/stampa | Chichester, UK ; ; Hoboken, NJ, : Wiley, 2003 |
| Descrizione fisica | 1 online resource (308 p.) |
| Disciplina |
571.4
571.7/7 571.77 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Circadian rhythms
Photobiochemistry |
| ISBN |
1-280-26907-3
9786610269075 0-470-09082-0 0-470-09083-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MOLECULAR CLOCKS AND LIGHT SIGNALLING; Contents; Participants; Chair's introduction; Non-rod, non-cone photoreception in rodents and teleost fish; Discussion; Cryptochromes and inner retinal non-visual irradiance detection; Discussion; General discussion I; Light signalling in Cryptochrome-deficient mice; Discussion; Circadian light input in plants, flies, and mammals; Discussion; Orphan nuclear receptors, molecular clockwork, and the entrainment of peripheral oscillators; Discussion; General discussion; SCN: ringmaster of the circadian circus or conductor of the circadian orchestra?
DiscussionOn the communication pathways between the central pacemaker and peripheral oscillators; Discussion; Central and peripheral circadian oscillators in Drosophila; Discussion; Integration of molecular rhythms in mammalian circadian system; Circadian transcriptional output in the SCN and liver of the mouse; Discussion; The molecular workings of the Neurospora biological clock; Discussion; Expression of clock gene products in the suprachiasmatic nucleus in relation to circadian behaviour; Discussion; Circadian rhythms in Drosophila; Discussion The role of phosphorylation and degradation of hPer proteins oscillation in normal human fibroblastsDiscussion; Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signalling; Discussion; CK1 and GSK-3 in the Drosophila and mammalian circadian clock; Discussion; Final general discussion; Closing remarks; Index of contributors; Subject index |
| Record Nr. | UNINA-9910841720503321 |
| Chichester, UK ; ; Hoboken, NJ, : Wiley, 2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Mucus hypersecretion in respiratory disease [[electronic resource]]
| Mucus hypersecretion in respiratory disease [[electronic resource]] |
| Pubbl/distr/stampa | Chichester, West Sussex, England ; ; Hoboken, NJ, USA, : Wiley, 2002 |
| Descrizione fisica | 1 online resource (304 p.) |
| Disciplina | 616.2 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Mucous membrane
Respiratory organs - Diseases |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-27111-6
9786610271115 0-470-66827-X 0-470-85929-6 0-470-86079-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MUCUS HYPERSECRETION IN RESPIRATORY DISEASE; Contents; Participants; Chair's introduction; Epidemiological studies in mucus hypersecretion; Discussion; Post-secretory fate of host defence components in mucus; Discussion; Mechanisms of submucosal gland morphogenesis in the airway; Discussion; Mucin-producing elements and inflammatory cells; Discussion; Respiratory tract mucins: structure and expression patterns; Discussion; Development and validation of a lectin-based assay for the quantitation of rat respiratory mucin; Discussion; Regulation of mucin secretion from in vitro cellular models
DiscussionOscillations of pH inside the secretory granule control the gain of Ca(2+) release for signal transduction in goblet cells exocytosis; Discussion; A calcium-activated chloride channel blocker inhibits goblet cell metaplasia and mucus overproduction; Discussion; Mechanisms by which Gram-positive bacteria and tobacco smoke stimulate mucin induction through the epidermal growth factor receptor (EGFR); Discussion; Non-allergic models of mucous cell metaplasia and mucus hypersecretion in rat nasal and pulmonary airways; Discussion Cytokine regulation of mucus production in a model of allergic asthmaDiscussion; The role of apoptotic regulators in metaplastic mucous cells; Discussion; Current and future therapies for airway mucus hypersecretion; Discussion; Clinical evaluation of new therapies for treatment of mucus hypersecretion in respiratory diseases; Discussion; Final general discussion; Index of contributors; Subject index |
| Record Nr. | UNINA-9910143168603321 |
| Chichester, West Sussex, England ; ; Hoboken, NJ, USA, : Wiley, 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Mucus hypersecretion in respiratory disease [[electronic resource]]
| Mucus hypersecretion in respiratory disease [[electronic resource]] |
| Pubbl/distr/stampa | Chichester, West Sussex, England ; ; Hoboken, NJ, USA, : Wiley, 2002 |
| Descrizione fisica | 1 online resource (304 p.) |
| Disciplina | 616.2 |
| Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
| Collana | Novartis Foundation symposium |
| Soggetto topico |
Mucous membrane
Respiratory organs - Diseases |
| ISBN |
1-280-27111-6
9786610271115 0-470-66827-X 0-470-85929-6 0-470-86079-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MUCUS HYPERSECRETION IN RESPIRATORY DISEASE; Contents; Participants; Chair's introduction; Epidemiological studies in mucus hypersecretion; Discussion; Post-secretory fate of host defence components in mucus; Discussion; Mechanisms of submucosal gland morphogenesis in the airway; Discussion; Mucin-producing elements and inflammatory cells; Discussion; Respiratory tract mucins: structure and expression patterns; Discussion; Development and validation of a lectin-based assay for the quantitation of rat respiratory mucin; Discussion; Regulation of mucin secretion from in vitro cellular models
DiscussionOscillations of pH inside the secretory granule control the gain of Ca(2+) release for signal transduction in goblet cells exocytosis; Discussion; A calcium-activated chloride channel blocker inhibits goblet cell metaplasia and mucus overproduction; Discussion; Mechanisms by which Gram-positive bacteria and tobacco smoke stimulate mucin induction through the epidermal growth factor receptor (EGFR); Discussion; Non-allergic models of mucous cell metaplasia and mucus hypersecretion in rat nasal and pulmonary airways; Discussion Cytokine regulation of mucus production in a model of allergic asthmaDiscussion; The role of apoptotic regulators in metaplastic mucous cells; Discussion; Current and future therapies for airway mucus hypersecretion; Discussion; Clinical evaluation of new therapies for treatment of mucus hypersecretion in respiratory diseases; Discussion; Final general discussion; Index of contributors; Subject index |
| Record Nr. | UNINA-9910831021203321 |
| Chichester, West Sussex, England ; ; Hoboken, NJ, USA, : Wiley, 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
