IgE, mast cells, and the allergic response [[electronic resource]]

• Pubblicazione: Chichester ; ; New York, : John Wiley & Sons, 1989
• Descrizione fisica: 1 online resource (294 p.)
• Disciplina: 599.0293; 616.07; 616.079
• Soggetto topico: Immunoglobulin E; Mast cells - Immunology; Allergy - Pathogenesis
• Altri autori: ChadwickDerek
• Note generali: "Symposium on IgE, Mast Cells, and the Allergic Response, held at the Ciba Foundation, London, 11-13 April 1989"--Contents p.; Edited and organized by Derek Chadwick and others.; "A Wiley-Interscience publication."
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: IgE, MAST CELLS AND THE ALLERGIC RESPONSE; Contents; Introduction; Control of in vivo IgE production in the mouse by interleukin 4; Structure and function of FcE receptor II (FcE,RII/CD23): a point of contact between the effector phase of allergy and B cell differentiation; Different mast cell mediators produced by different mast cell phenotypes; Mast cells: immunologically specific effectors and potential sources of multiple cytokines during IgE-dependent responses; Non-IgE-mediated mast cell stimulation; The receptor with high affinity for IgE ; Calcium: an important second messenger in mast cellsLow affinity IgE receptors: regulation and functional roles in cell activation; IgE and inflammatory cells; Molecular genetics of human responsiveness to allergens; Influence of environmental factors on IgE production; Epidemiology of the allergic response; Heterogeneity of human FcERI-bearing cells; Conventional and new approaches to hyposensitization; Final general discussion; Closing statement; Index of contributors; Subject index
• Sommario/riassunto: Reviews recent basic research into IgE, mast cells, and the allergic response and the relevance of this work to human pathophysiology, and discusses new methods of treatment. This symposium is unique in the IgE field for its breadth of coverage and interdisciplinary nature, and it shows the benefits from the current rapid expansion of knowledge in cell biology, immunology, and molecular genetics, as well as the potential clinical significance of this research to clinical immunologists and allergologists.
• Titolo autorizzato: IgE, mast cells, and the allergic response
• ISBN: 1-282-34762-4; 9786612347627; 0-470-51386-1; 0-470-51387-X
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910830783703321
• Lo trovi qui: Univ. Federico II
• Serie: Ciba Foundation symposium ; ; 147.