Redox biochemistry / / edited by Ruma Banerjee ; associate editors, Donald Becker ... [et al.]

• Pubblicazione: Hoboken, N.J., : Wiley-Interscience, c2008
• Edizione: 1st ed.
• Descrizione fisica: 1 online resource (339 p.)
• Disciplina: 541/.393
• Soggetto topico: Oxidation-reduction reaction - Physiological effect
• Altri autori: BanerjeeRuma
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: REDOX BIOCHEMISTRY; CONTENTS; Contributors; List of Abbreviations; Preface; 1. Redox Metabolism and Life; 1.1. Redox Biochemistry and the Evolution of Life; 1.2. Global Redox Cycles; 1.3. Major Bioenergetic Cycles; 1.3.A. Photosynthesis; 1.3.B. Aerobic Respiration; 2. Antioxidant Molecules and Redox Cofactors; 2.1. Glutathione; 2.1.A. Biological Functions; 2.1.B. Biosynthesis; 2.1.C. Degradation; 2.1.D. Other Thiol-Based Redox Buffers; 2.2. Ascorbate; 2.2.A. Ascorbate Chemistry; 2.2.B. Ascorbate Biosynthesis; 2.2.C. Ascorbate Recycling; 2.2.D. Ascorbate Transport ; 2.2.E. Importance of Ascorbate in Stress and Disease2.3. Other Antioxidants; 2.3.A. Lipid-Soluble Antioxidants; 2.3.B. Water-Soluble Antioxidants; 2.3.C. Antioxidants and Human Health; 2.4. Redox Coenzymes; 2.4.A. Flavin; 2.4.B. NAD; 2.4.C. Quinones; 2.4.D. Pterins and Molybdopterins; 2.4.E. Folic Acid; 3. Antioxidant Enzymes; 3.1. ROS-Dependent Enzymes; 3.1.A. Catalase; 3.1.B. Superoxide Dismutase; 3.1.C. Peroxiredoxins; 3.1.D. Alkyl Hydroperoxide Reductases; 3.2. The Thioredoxin System; 3.2.A. Thioredoxin; 3.2.B. Thioredoxin Reductase; 3.3. The Glutathione System ; 3.3.A. Glutathione Reductase3.3.B. Glutaredoxin (Thioltransferase); 3.4. Repair Enzymes; 3.4.A. Methionine Sulfoxide Reductases; 3.4.B. DNA Repair Enzymes; 3.4.C. Sulfiredoxins; 3.5. Detoxification Enzymes; 3.5.A. Cytochrome P450 Enzymes: Structure, Function, and Mechanism; 3.5.B. GSH Transferases; 3.6. Oxidative Folding; 3.6.A. Disulfide Bond Formation in Bacteria; 3.6.B. Disulfide Bond Formation in Eukaryotes; 3.7. Other Antioxidant Enzymes; 3.7.A. Selenoproteins; 3.7.B. Heme Oxygenase; 4. Redox Regulation of Physiological Processes ; 4.1. Reactive Oxygen, Nitrogen, and Thiol-Based Signal Transduction4.1.A. Nitric Oxide Signaling; 4.1.B. Carbon Monoxide Signaling; 4.1.C. Superoxide and Hydrogen Peroxide; 4.1.D. Other Novel Redox Molecules; 4.2. Role of Nitric Oxide Synthases in Redox Signaling; 4.2.A. Characterization of the Nitric Oxide Synthases; 4.2.B. Regulation of Nitric Oxide Synthases by Intrinsic Elements; 4.2.C. Extrinsic Regulation of Nitric Oxide Synthases; 4.2.D. Interactions of NO with Other Proteins and Enzymes; 4.3. Redox Regulation of Genes; 4.3.A. MAP Kinase/Cell Cycle ; 4.3.B. Redox Control of Gene Expression4.3.C. Peptide Editing and Thiol-Mediated Redox Regulation; 4.4. Redox Regulation of Apoptosis; 4.4.A. Apoptotic Pathways; 4.4.B. Reactive Oxygen Species and Apoptosis; 4.5. Metal Homeostasis; 4.5.A. Physiological Significance of Metal Metabolism; 4.5.B. Metal Uptake from the Extracellular Environment; 4.5.C. Intracellular Metal Distribution by Target-Specific Chaperones; 4.5.D. Subcellular Membrane Metal Transporters; 4.5.E. Heme and Iron-Sulfur Cluster Synthesis; 4.5.F. Cellular Storage; 4.5.G. Metal Export; 4.5.H. Regulation of Metal Metabolism ; 4.5.I. Genetic Disorders in Metal Metabolism
• Sommario/riassunto: This is the premier, single-source reference on redox biochemistry, a rapidly emerging field. This reference presents the basic principles and includes detailed chapters focusing on various aspects of five primary areas of redox biochemistry: antioxidant molecules and redox cofactors; antioxidant enzymes; redox regulation of physiological processes; pathological processes related to redox; and specialized methods. This is a go-to resource for professionals in pharmaceuticals, medicine, immunology, nutrition, and environmental fields and an excellent text for upper-level students.
• Titolo autorizzato: Redox biochemistry
• ISBN: 9786611221508; 9781281221506; 1281221503; 9780470177334; 0470177330; 9780470177327; 0470177322
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910829111303321
• Lo trovi qui: Univ. Federico II