Molecular biology of RNA : new perspectives / / edited by Masayori Inouye, Bernard S. Dudock

• Pubblicazione: San Diego : , : Academic Press, , [1987]; ©1987
• Descrizione fisica: 1 online resource (464 p.)
• Disciplina: 574.87/3283
• Soggetto topico: RNA; Molecular biology; Molecular genetics
• Persona (resp. second.): InouyeMasayori; DudockBernard S.
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographies and index.
• Nota di contenuto: Front Cover; Molecular Biology of RNA: New Perspectives; Copyright Page; Table of Contents; Preface; PART I: RNA as an Enzyme; Chapter 1. Cleavage of RNA by RNAse P from Escherichia coli; I. Introduction; II. Aspects of the RNase P Reaction; III. Studies of Enzyme-Substrate Interactions; IV. Structure-Function Relationships in Ml RNA; V. Studies of the Protein Subunit of RNase P; VI. Hybrid Enzymes; VII. Conclusion; References; Chapter 2. Bacillus subtilis RNase P; I. The RNase P Components; II. Mechanism of RNase P Cleavage; III. Toward the Higher-Order Structure of RNase P RNA ; IV. Structure-Function Relationships in the RNase P RNAV. Why Is the Catalytic Element of RNase P Composed of RNA?; References; Chapter 3. Multiple Enzymatic Activities of an Intervening Sequence RNA from Tetrahymena; I. Introduction; II. Self-Splicing RNA; III. The IVS RNA Enzyme; References; Chapter 4. Processing and Genetic Characterization of Self-Splicing RNAs of Bacteriophage T4; I. Introduction; II. Group I Splicing Mechanism for T4 td RNA; III. Nondirected Mutagenesis and Delineation of Two Functional Domains for Splicing in the td Intron; IV. Multiple Self-Splicing Introns in T4 ; V. ConclusionsReferences; PART II: RNA Splicing; Chapter 5. The Mammalian Pre-Messenger RNA Splicing Apparatus: A Ribosome in Pieces?; I. Introduction; II. The Discovery of snRNPs; III. The snRNPs-and-Splicing Hypothesis; IV. snRNP Components and Structure; V. Is Eukaryotic RNase P an Sm snRNP?; VI. Ul snRNPs Bind 5' Splice Sites; VII. U2, U5, and U4/U6 snRNPs Also Participate in Splicing; VIII. The Spliceosome-Ribosome Analogy; References; Chapter 6. Exon Sequences and Splice Site Proximity Play a Role in Splice Site Selection; I. Introduction ; II. Exon Sequences and Splice Site Proximity Play a Role in Splice Site SelectionIII. The Pattern of Splice Site Selection Is Altered in Different Extract Preparations and in Diluted Extracts; IV. Splice Site Selection Can Be Altered by Competition in Trans; V. Discussion; References; Chapter 7. Factors That Influence Alternative Splice Site Selection in Vitro; I. Introduction; II. Materials and Methods; III. Results; IV. Discussion; References; Chapter 8. Messenger RNA Splicing in Yeast; I. An Overview of Nuclear mRNA Splicing ; II. Preliminary in Vitro and in Vivo Characterization of Yeast mRNA SplicingIII. Characterization of Mutations in the Splicing Process; IV. The RNA Gene Products and the Spliceosome; V. Speculation; References; Chapter 9. Architecture of Fungal Introns: Implications for Spliceosome Assembly; I. Introduction; II. Branch Site-3' Splice Junction Relationship; III. Branch Site-5' Splice Junction Relationship; IV. Perspectives; References; Chapter 10. RNA Joining and Trypanosome Gene Expression; I. Introduction; II. Materials and Methods; III. Results; IV. Discussion; V. Summary; References ; PART III: RNA Viruses
• Sommario/riassunto: Molecular Biology of RNA: New Perspectives provides an overview of the developments in RNA research as well as the approaches, strategies, and methodologies used. Most of the contributing authors in the present volume participated in the Fifth Stony Brook Symposium entitled ""New Perspectives on the Molecular Biology of RNA"" in May 1986. The text is organized into six parts. Part I contains papers dealing with RNA as an enzyme. Part II presents studies on RNA splicing. Part III examines RNA viruses while Part IV focuses on the role of RNA in DNA replication. Part V is devoted to the structure
• Titolo autorizzato: Molecular biology of RNA
• ISBN: 1-4832-7390-3
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910789454303321
• Lo trovi qui: Univ. Federico II