Plant secondary metabolites : physico-chemical properties and therapeutic applications / / edite by Anil Kumar Sharma, Ajay Sharma

• Pubblicazione: Singapore : , : Springer, , [2022]; ©2022
• Descrizione fisica: 1 online resource (479 pages)
• Disciplina: 306.4409113
• Soggetto topico: Plant metabolites - Biotechnology
• Persona (resp. second.): SharmaAnil Kumar; SharmaAjay
• Nota di bibliografia: Includes bibliographical references.
• Nota di contenuto: Intro -- Preface -- Contents -- About the Editors -- 1: Plant Secondary Metabolites: An Introduction of Their Chemistry and Biological Significance with Physicochemical Aspect -- 1.1 Introduction -- 1.2 Phenolics and Polyphenolics -- 1.2.1 Flavonoids -- 1.2.2 Non-flavonoids -- 1.3 Nitrogen-Containing Compounds -- 1.3.1 Alkaloids -- 1.3.1.1 True Alkaloids -- 1.3.1.2 Protoalkaloids -- 1.3.1.3 Pseudoalkaoids -- 1.3.1.4 Polyamines Alkaloids -- 1.3.1.5 Peptide and Cyclopeptide Alkaloids -- 1.3.2 Cyanogenic Glycosides -- 1.3.3 Glucosinolates -- 1.3.4 Nonprotein Amino Acid -- 1.4 Terpenes/Terpenoids -- 1.4.1 Hemiterpenoids -- 1.4.2 Monoterpenoids -- 1.4.3 Sesquiterpenoids -- 1.4.4 Diterpenoids -- 1.4.5 Sesterterpenoids -- 1.4.6 Triterpenoids -- 1.4.7 Sesquarterpenoids -- 1.4.8 Tetraterpenoids -- 1.4.9 Polyterpenoids -- 1.4.10 Irregular Terpenoids -- 1.5 Sulfur-Containing Compounds -- 1.5.1 Phytochelatins -- 1.5.2 Glucosinolate -- 1.5.3 Phytoalexins -- 1.5.4 Defensins -- 1.5.5 Thionins -- 1.6 Physiochemical Aspect of Plant Secondary Metabolites (PSMs) -- 1.7 Biological Activities of Plant Secondary Metabolites (PSMs) -- 1.7.1 Antioxidant Effects -- 1.7.2 Antimicrobial Effects -- 1.7.3 Anticancer Effects -- 1.7.4 Antidiabetic Effects -- 1.7.5 Anti-inflammatory Effect -- 1.7.6 Antidepressant -- 1.8 Conclusion -- References -- Chapter 2: Natural Sources of Plant Secondary Metabolites and the Role of Plant Polyphenols in the Green Photosynthesis of Met... -- 2.1 Plant Secondary Metabolites: From Plants to Industrial Products -- 2.2 Plant Polyphenols -- 2.2.1 Flavonoids -- 2.2.2 Lignans -- 2.2.3 Stilbenes -- 2.2.4 Phenolic Acid -- 2.3 Phytosynthesis of Metallic Nanoparticles -- 2.4 Polyphenols in Nanoparticle Phytosynthesis -- 2.4.1 Nanoparticle Synthesis Methods -- 2.4.2 Characterization and Properties -- 2.4.3 Flavonoids in Nanoparticle Phytosynthesis. ; 2.4.3.1 Platycladi cacumen Extract in Silver Nanoparticle Synthesis -- 2.4.3.2 Selaginella bryopteris (L.) Baker (1884) Extract in Silver Nanoparticle Synthesis -- 2.4.3.3 Salvia officinalis L. Extract in Silver Nanoparticle Synthesis -- 2.4.3.4 Chenopodium murale L. Leaf Extract in Silver Nanoparticle Synthesis -- 2.4.4 Phenolic Acids in Nanoparticle Phytosynthesis -- 2.4.4.1 Camellia sinensis (L.) Kuntze Extract in Silver Nanoparticle Synthesis -- 2.4.4.2 Parkia speciosa Hassk. Extract in Silver Nanoparticle Synthesis -- 2.4.5 Lignans in Nanoparticle Phytosynthesis -- 2.4.5.1 Forsythia suspensa (Thunberg) Vahl Fruit Extract in Silver Nanoparticle Synthesis -- 2.4.5.2 Sesamum indicum L. Extract in Silver Nanoparticle Synthesis -- 2.4.5.3 Streblus asper Lour. Extract in Silver Nanoparticle Synthesis -- 2.4.6 Stilbenes in Nanoparticle Phytosynthesis -- 2.5 Concluding Remarks and Perspectives -- References -- 3: Plant Secondary Metabolite Determination Through Analytical Chromatographic Techniques: Recent Trends and Advancement -- 3.1 Introduction -- 3.1.1 High-Pressure Thin-Layer Chromatography (HPTLC) -- 3.1.2 High-Pressure Liquid Chromatography -- 3.1.3 GC-MS -- 3.2 Conclusion -- References -- 4: Role of Plant Secondary Metabolites as Anticancer and Chemopreventive Agents -- 4.1 Introduction -- 4.2 Side Effects Associated with Cancer Treatment Regimes -- 4.3 Plant Secondary Metabolites as Anticancer Agents -- 4.3.1 Terpenoids or Terpenes -- 4.3.1.1 Monoterpenoids -- 4.3.1.2 Sesquiterpenoid -- 4.3.1.3 Diterpenoids -- 4.3.1.4 Triterpenoids -- 4.3.1.5 Tetraterpenoids -- 4.3.2 Polyphenols -- 4.3.2.1 Curcumin -- 4.3.2.2 Quercetin -- 4.3.2.3 Resveratrol -- 4.3.2.4 Flavonoids -- 4.3.3 Nitrogen-Containing Compounds -- 4.3.3.1 Alkaloids -- Indole Alkaloids -- Isoquinoline Alkaloids -- Phenanthroindolizidine Alkaloids -- Indoquinoline Alkaloids. ; Benzophenanthridine Alkaloids -- 4.3.3.2 Glucosinolates -- 4.4 Conclusion -- References -- 5: Plant Secondary Metabolites: Natural Compounds as Cosmetic Ingredients and Their Potential Activity in Skin Cancer -- 5.1 Introduction -- 5.2 Skin Cancer Therapy -- 5.2.1 Basal Cell Carcinoma -- 5.2.2 Squamous Cell Carcinoma -- 5.2.3 Melanoma -- 5.3 Phytochemicals -- 5.3.1 Polyphenolic Compounds -- 5.3.1.1 Quercetin -- 5.3.1.2 Apigenin -- 5.3.1.3 Silymarin and Silybin -- 5.3.1.4 Diosmin -- 5.3.1.5 Fisetin -- 5.3.1.6 Luteolin -- 5.3.1.7 Catechins -- 5.3.1.8 Curcumin -- 5.3.1.9 Resveratrol -- 5.3.2 Polysaccharides -- 5.3.3 Volatile Oils -- 5.3.3.1 Terpin-4-Ol -- 5.3.3.2 Geraniol -- 5.3.3.3 α-Pinene -- 5.3.3.4 α-Santalol -- 5.3.3.5 Eugenol -- 5.3.3.6 Boswellic Acids -- 5.3.4 Alkaloids -- 5.3.4.1 Berberine -- 5.3.4.2 Paclitaxel -- 5.3.4.3 Glycoalkaloids Isolated from Solanaceae -- 5.3.5 Proanthocyanidins -- 5.3.6 Caffeic Acid Phenethyl Ester -- 5.3.7 Allyl Sulfides -- 5.3.8 Capsaicin -- 5.4 Conclusions -- References -- 6: Natural Remedies for a Healthy Heart: The Evidence-Based Beneficial Effects of Polyphenols -- 6.1 Background -- 6.2 Structure and Bioavailability of Vegetal Secondary Metabolites -- 6.2.1 Terpenes -- 6.2.2 Nitrogen and Sulfur-Containing Compounds -- 6.2.3 Phenolic Compounds -- 6.2.4 Polyphenols Bioavailability -- 6.3 The General Mechanism Responsible for the Beneficial Effects of Polyphenols in CVD -- 6.4 Beneficial Actions of Polyphenols Concerning Redox Homeostasis -- 6.4.1 Direct Antioxidant Action -- 6.4.2 Indirect Action Supporting Antioxidant Systems -- 6.4.3 Indirect Action Inhibiting Oxidative Stress-Enhancing Systems -- 6.4.4 Reports Regarding Antioxidant Effects in Human Studies -- 6.5 Protective Effects Involving Lipid Metabolism -- 6.5.1 Preclinical Reports -- 6.5.2 Clinical Evidence. ; 6.6 Polyphenols and Platelet Function: Experimental and Preclinical Results -- 6.6.1 Antiplatelet Effects in Clinical Settings -- 6.7 Polyphenols and Inflammation -- 6.7.1 Experimental Studies Supporting the Effect of Polyphenols on Inflammatory Pathways -- 6.7.2 Anti-inflammatory Effects of Polyphenols in Preclinical and Clinical Settings -- 6.8 Conclusions -- References -- 7: Kauranes as Anti-inflammatory and Immunomodulatory Agents: An Overview of In Vitro and In Vivo Effects -- 7.1 Introduction -- 7.2 Chemistry of Kauranes -- 7.3 Anti-inflammatory Activity of Kauranes on Cells of the Immune System -- 7.3.1 Anti-inflammatory Effects on Neutrophils -- 7.3.2 Anti-inflammatory Effects on Monocytes and Macrophages -- 7.3.2.1 Effect of Kauranes on Monocytes and Peripheral Macrophages -- 7.3.2.2 Effects on Macrophages of the Central Nervous System (Microglia) -- 7.3.3 Anti-inflammatory Effects on Dendritic Cells -- 7.3.4 Anti-inflammatory Effects on CD4+ Helper T-Cell Activation and Differentiation -- 7.4 Other Anti-inflammatory Effects Associated with Kauranes -- 7.5 In Vivo Effects in Animal Models -- 7.5.1 Effects of Kauranes in Animal Models of Acute Inflammation -- 7.5.2 Effects of Kauranes in Animal Models of Rheumatoid Arthritis -- 7.5.3 Effects of Kauranes in Animal Models of SLE -- 7.5.4 Effects of Kauranes in Animal Models of IBD -- 7.5.5 Effects of Kauranes in Animal Models of Lung Conditions -- 7.5.6 Effects of Kauranes in Animal Models of Acute Liver Injury, Hepatotoxicity, and Liver Fibrosis -- 7.5.6.1 Acute Liver Injury -- 7.5.6.2 Hepatotoxicity -- 7.5.6.3 Liver Fibrosis -- 7.5.7 Effects of Kauranes in Animal Models of Neurological Diseases -- 7.5.7.1 Alzheimer´s Disease -- 7.5.7.2 Parkinson´s Disease -- 7.5.7.3 Multiple Sclerosis -- 7.5.7.4 Guillain-Barré Syndrome -- 7.5.8 Effects of Kauranes in Animal Models of Diabetes. ; 7.5.9 Effects of Kauranes in Other Animal Models of Inflammation In Vivo -- 7.6 Future Perspectives -- 7.7 Conclusions -- References -- 8: Role of Plant Secondary Metabolites in Metabolic Disorders -- 8.1 Introduction -- 8.1.1 Physiology of Metabolism -- 8.1.2 Cell: The Metabolic Processing Center -- 8.2 Introduction to Metabolic Disorders -- 8.3 Association of Significant Dietary Habits with Metabolic Syndrome -- 8.4 Causes of Metabolic Disorders -- 8.5 Role of Polyphenols in Health -- 8.6 Polyphenols and Their Role in the Human Body -- 8.7 Metabolic Syndrome and Oxidative Stress -- 8.8 Phytotherapeutic and Metabolic Disorders -- 8.9 Role of Secondary Metabolites in Type 1 and Type 2 Diabetes Mellitus -- 8.10 Plant Metabolism and Secondary Metabolites -- 8.11 Importance and Main Role of Secondary Metabolites -- 8.12 Antioxidant Potential of Plant Phenols -- 8.13 Classification of Secondary Metabolites -- 8.14 Role of Secondary Metabolites in Thyroid Disease -- 8.15 Plant Polyphenols and Hepatitis -- 8.16 Secondary Metabolites in the Prevention of Hepatorenal Toxicity -- 8.17 Secondary Metabolites in Tuberculosis and Their Potency Against Tuberculosis -- 8.17.1 First Line Drugs -- 8.17.1.1 Isoniazid -- 8.17.1.2 Rifampicin -- 8.17.1.3 Ethambutol -- 8.17.1.4 Pyrazinamide -- 8.17.1.5 Streptomycin -- 8.17.2 Second-Line Medications -- 8.17.2.1 Fluoroquinolone -- 8.17.2.2 Aminoglycosides (Kanamycin, Amikacin, and Capreomycin) -- 8.17.2.3 Ethionamide and Prothionamide Ethionamide -- 8.17.2.4 P-Aminosalicylic Acid -- 8.17.2.5 Cycloserine -- 8.18 Therapeutic Use of Phytopolyphenols -- References -- 9: Metal Complexes of Plant Secondary Metabolites with Therapeutic Potential -- 9.1 Introduction -- 9.2 Classification -- 9.2.1 Terpenes -- 9.2.2 Nitrogen-Containing Compounds -- 9.2.3 Phenolics -- 9.2.4 Sulfur-Containing Compounds -- 9.3 Antioxidant Activity. ; 9.4 Cytotoxic Activity for Cancer Therapy.
• Titolo autorizzato: Plant secondary metabolites
• ISBN: 981-16-4778-X; 981-16-4779-8
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910743239203321
• Lo trovi qui: Univ. Federico II