Handbook of HER2-targeted agents in breast cancer [[electronic resource] /] / by Ricardo H Alvarez, Javier Cortés, Leticia Mattos-Arruda, Mary Falzon, Angelica Fasolo, Michael Gandy, Luca Gianni, Nadia Harbeck, Martine Piccart, Stefania Zambelli, Dimitrios Zardavas
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| Autore: |
Alvarez Ricardo H
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| Titolo: |
Handbook of HER2-targeted agents in breast cancer [[electronic resource] /] / by Ricardo H Alvarez, Javier Cortés, Leticia Mattos-Arruda, Mary Falzon, Angelica Fasolo, Michael Gandy, Luca Gianni, Nadia Harbeck, Martine Piccart, Stefania Zambelli, Dimitrios Zardavas
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| Pubblicazione: | Tarporley : , : Springer Healthcare Ltd. : , : Imprint : Springer Healthcare, , 2013 |
| Edizione: | 1st ed. 2013. |
| Descrizione fisica: | 1 online resource (107 p.) |
| Disciplina: | 616.99449 |
| Soggetto topico: | Oncology |
| Primary care (Medicine) | |
| General practice (Medicine) | |
| Internal medicine | |
| Pharmacotherapy | |
| Oncology | |
| Primary Care Medicine | |
| General Practice / Family Medicine | |
| Internal Medicine | |
| Persona (resp. second.): | CortésJavier |
| Mattos-ArrudaLeticia | |
| FalzonMary | |
| FasoloAngelica | |
| GandyMichael | |
| GianniLuca | |
| HarbeckNadia | |
| PiccartMartine | |
| ZambelliStefania | |
| ZardavasDimitrios | |
| Note generali: | Description based upon print version of record. |
| Nota di bibliografia: | Includes bibliographical references. |
| Nota di contenuto: | Introduction and background biology -- HER2 testing -- HER2-positive breast cancer: adjuvant and neoadjuvant therapy -- HER2-positive metastatic breast cancer: first-line treatment -- HER2-positive metastatic breast cancer: second-line treatment -- Emerging targeted agents for HER2-positive breast cancer. |
| Sommario/riassunto: | Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide, accounting for nearly a quarter of the total new cancer cases each year. Of these cases, approximately 15–25% overexpress HER2, a transmembrane RTK kinase that is associated with aggressive tumor growth and poor outcomes. However, in the past decade, survival rates of patients with HER-positive breast cancer have significantly improved due to increased screening, HER2 testing, and breakthrough HER2-targeted drug therapies. Handbook of HER2-Targeted Agents in Breast Cancer provides oncologists, primary care physicians, trainees and other healthcare providers with a concise, accessible, and up-to-date survey of the field, including a review of our current understanding of the biology of the HER2 pathway and the rationale for targeting it in early-stage and advanced breast cancer, an overview of HER2-testing, and evidence-based discussions of available HER2-targeted regimens in the adjuvant and metastatic settings. |
| Titolo autorizzato: | Handbook of HER2-targeted agents in breast cancer |
| ISBN: | 1-907673-94-6 |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910438014903321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |