Untranslated gene regions and other non-coding elements : regulation of eukaryotic gene expression / / Lucy W. Barrett, Sue Fletcher, Steve D. Wilton
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| Autore: |
Barrett Lucy W
|
| Titolo: |
Untranslated gene regions and other non-coding elements : regulation of eukaryotic gene expression / / Lucy W. Barrett, Sue Fletcher, Steve D. Wilton
|
| Pubblicazione: | Basel, : Springer, 2013 |
| Edizione: | 1st ed. 2013. |
| Descrizione fisica: | 1 online resource (63 p.) |
| Disciplina: | 570 |
| 572.88 | |
| Soggetto topico: | Gene expression |
| Genetic regulation | |
| Altri autori: |
FletcherSue
WiltonSteve D
|
| Note generali: | Description based upon print version of record. |
| Nota di bibliografia: | Includes bibliographical references. |
| Nota di contenuto: | Introduction -- Promoter -- 5’ Untranslated Region -- Structure -- Intronic Regions -- 3’ Untranslated Region -- Non-coding RNAs -- Conclusion. |
| Sommario/riassunto: | There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution. |
| Titolo autorizzato: | Untranslated gene regions and other non-coding elements |
| ISBN: | 3-0348-0679-5 |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910437608003321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
SpringerBriefs in Biochemistry and Molecular Biology, . 2211-9353