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Electrospun and electrosprayed formulations for drug delivery / / special issue editors, Ian S. Blagbrough, Gareth R. Williams



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Titolo: Electrospun and electrosprayed formulations for drug delivery / / special issue editors, Ian S. Blagbrough, Gareth R. Williams Visualizza cluster
Pubblicazione: MDPI - Multidisciplinary Digital Publishing Institute, 2019
Descrizione fisica: 1 electronic resource (190 p.)
Disciplina: 615.1/9
Soggetto topico: Drug delivery systems
Electrospinning
Nanoparticles
Soggetto non controllato: tissue engineering
cyclodextrin
permeability
poly (vinylpyrrolidone-co-vinyl acetate)
crystalline
antibacterial
drug delivery
homogenization
capsaicin
combination therapy
high-shear mixing
cyclodextrin-inclusion complexes
amorphous
high-speed electrospinning
PMVE/MA
aqueous solubility enhancement
sieve analysis
Raman mapping
Eudragit
nanofibers
psoriasis
PCL
essential oils
parameters
antibiotics
xanthan gum
carvedilol
amorphous composite
coaxial electrospinning
insoluble drug
NIR-triggered drug release
fast dissolution
electrospinning
oral drug delivery
electrospun nanofibers
poly-cyclodextrin
TRPV1
gallic acid
solid dispersion
photothermal therapy
drug release
applications
Persona (resp. second.): BlagbroughI. S (Ian S.)
WilliamsJ. R. G. <1978->
Sommario/riassunto: This book is comprised of important reviews and cutting-edge original research papers concerning electrospun and electrosprayed formulations in drug delivery. Electrospinning and electrospraying have, in recent years, attracted increasing attention in the pharmaceutical sector, with research in the area advancing rapidly. It is now possible to prepare extremely complex systems using multi-fluid processes, and to increase production rates to an industrial scale. Electrospun formulations can be produced under GMP conditions and are in clinical trials. In this volume, we explore a range of topics around electrospinning and electrospraying in controlled drug delivery. Four reviews cover the exciting potential of cyclodextrin-containing fibers and the many potential biomedical applications of electrospun fibers. The use of electrospinning to prepare amorphous systems and improve the dissolution rate and solubility of poorly soluble active ingredients is addressed, and the possibilities of such materials in tissue engineering are comprehensively covered. The six original research papers cover the effect of molecular properties on API release from Eudragit-based electrospun fibers; ferulic acid solid dispersions; electrospun medicines to treat psoriasis; scale up of electrospinning and its use to produce low-dose tablets; transepithelial permeation of drugs released from electrospun fibers, and the possibilities for the synergistic chemophotothermal treatment of cancer.
Titolo autorizzato: Electrospun and electrosprayed formulations for drug delivery  Visualizza cluster
ISBN: 3-03897-913-9
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910346691103321
Lo trovi qui: Univ. Federico II
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