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Heart Failure / / edited by Johann Bauersachs, Javed Butler, Peter Sandner



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Titolo: Heart Failure / / edited by Johann Bauersachs, Javed Butler, Peter Sandner Visualizza cluster
Pubblicazione: Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Edizione: 1st ed. 2017.
Descrizione fisica: 1 online resource (IX, 581 p. 100 illus., 30 illus. in color.)
Disciplina: 616.129
Soggetto topico: Pharmacology
Cardiology
Human physiology
Pharmacology/Toxicology
Human Physiology
Persona (resp. second.): BauersachsJohann
ButlerJaved
SandnerPeter
Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
Nota di contenuto: Introduction -- Epidemiology -- Clinical trial design, endpoints and regulatory requirements. Biomarkers HFpEF/HFrEF. Imaging Technologies / MRI and Echo. Comorbidities in HF. Current Guideline based therapy of HFreF and HFpEF. New and Emerging Therapies and Targets. Ivabradine -- Beta3 agonists -- Novel MRAs -- pGCs and Natriuretic peptides -- sGC stimulators -- PDE’s -- Adenosin and A1 Agonists -- Myosin heavy chain / Troponin -- Stem cells -- Diuretics and Vasopressin -- GeneTherapy -- RNA-based therapies and micro RNAs -- Cardiac myosin activation using gene therapy -- Bendavia – mitochondrial therapies -- WNT signaling -- Anticoagulation therapy and NOACS in HF -- Potassium Binders -- Iron. .
Sommario/riassunto: This special issue of the Handbook of Experimental Pharmacology on Heart Failure covers the entire spectrum of the field, from the current understanding and definitions of heart failure, to epidemiology and the importance of co-morbidities, clinical trial design and biomarkers, as well as imaging technologies. The main focus of this book is to review current and emerging heart failure therapies and potential targets for treatment.
Titolo autorizzato: Heart failure  Visualizza cluster
ISBN: 3-319-59659-4
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910253913903321
Lo trovi qui: Univ. Federico II
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Serie: Handbook of Experimental Pharmacology, . 0171-2004 ; ; 243