Adverse drug reactions / / edited by Anne Lee

• Pubblicazione: London ; ; Chicago : , : Pharmaceutical Press, , 2006
• Edizione: 2nd ed.
• Descrizione fisica: 1 online resource (xxi, 474 p. )
• Disciplina: 615/.7042
• Soggetto topico: Drugs - Side effects
• Persona (resp. second.): LeeAnne <1963->
• Note generali: Bibliographic Level Mode of Issuance: Monograph
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Cover -- Prelims -- Contents -- Preface -- Acknowledgements -- About the editor -- Contributors -- Chapter 1 - Introduction -- Epidemiology -- Classification and mechanisms -- Susceptibility -- Detection and diagnosis -- Healthcare professionals and adverse drug reactions -- References -- Further reading -- Chapter 2 - Side effects and patients -- Introduction -- Desire for information about side effects -- General perceptions -- Side effects and compliance -- Mandatory patient information leaflets -- Format of side-effect data for patients -- Key effects to consider when presenting side-effect data -- Patient reporting of ADRs -- The way forward -- References -- Further reading -- Chapter 3 - Pharmacogenetics and adverse drug reactions -- Introduction -- Adverse drug reactions -- Drug action -- Genetics revisited -- Genetic polymorphism and drug transporters -- Genetically determined pharmacodynamic variations -- Human leukocyte antigens and adverse drug reactions -- Utility of pharmacogenetics in the clinical setting -- References -- Further reading -- Glossary -- Chapter 4 - Adverse drug reactions in pregnancy -- Introduction -- Prescribing in pregnancy -- Drugs used to treat selected cardiovascular system disorders -- Drugs used to treat epilepsy -- Mental health disorders -- Drugs used in endocrine disorders -- Drugs used to treat infections -- Miscellaneous agents -- Summary -- References -- Further reading -- Glossary -- Chapter 5 - Drug-induced skin reactions -- Introduction -- Classification and mechanism -- Diagnosis -- Management points -- Exanthematous (erythematous) reactions -- Fixed drug eruption -- Urticaria and angio-oedema -- Acne -- Psoriasis and psoriasiform eruptions -- Purpura -- Vasculitis -- Erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis -- Blistering drug eruptions -- Photosensitivity. ; Lichenoid drug eruptions -- Pigmentary disorders -- Alopecia -- Hair gain -- Nail disorders -- References -- Further reading -- Chapter 6 - Gastrointestinal disorders -- Introduction -- The mouth -- The oesophagus -- Nausea and vomiting -- Stomach and duodenum -- Small intestine -- Colon -- Constipation -- Pancreatitis -- References -- Further reading -- Chapter 7 - Hepatic disorders -- Introduction -- Classification and mechanisms -- Signs and symptoms of liver disorders -- Risk factors -- Diagnosis of drug-induced liver damage -- Types of drug-induced liver disease -- Management of patients with drug-induced hepatic disease -- Prevention of drug-induced hepatic damage -- References -- Further reading -- Chapter 8 - Renal disorders -- Introduction -- Risk factors -- Diagnosis of drug-induced renal dysfunction -- Acute renal failure -- Chronic renal failure -- Nephrogenic diabetes insipidus -- Haemolytic uraemic syndrome -- Osmotic nephrosis -- Conclusion -- References -- Further reading -- Chapter 9 - Endocrine and metabolic disorders -- Introduction -- Drugs affecting thyroid function -- Medicines that may interfere with thyroid function tests -- Drugs affecting adrenal function -- Aldosterone synthesis -- Drugs affecting gonadotrophin release and gonadal function -- Hyperprolactinaemia -- Syndrome of inappropriate secretion of antidiuretic hormone -- Hyperglycaemia and diabetes -- Hypoglycaemia -- Disorders of fat metabolism -- References -- Further reading -- Chapter 10 - Respiratory disorders -- Introduction -- Nasal congestion -- Airway obstruction -- Parenchymal lung disorders -- Pulmonary oedema -- Pulmonary thromboembolism -- References -- Further reading -- Chapter 11 - Musculoskeletal disorders -- Introduction -- Muscle disorders -- Bone -- Joints -- Connective tissue -- References -- Further reading -- Chapter 12 - Blood disorders. ; Introduction -- Aplastic anaemia -- Agranulocytosis -- Thrombocytopenia -- Pure red cell aplasia -- Haemolytic anaemia -- Megaloblastic anaemia -- References -- Further reading -- Chapter 13 - Mental health disorders -- Introduction -- Depression -- Psychosis -- Mania -- Behavioural toxicity -- Cognitive impairment -- Psychiatric manifestations of drug withdrawal reactions -- Use of SSRIs and venlafaxine in children and adolescents with major depressive disorder (MDD) -- Serotonin syndrome and neuroleptic malignant syndrome -- Management of drug-induced psychiatric disturbances -- References -- Further reading -- Chapter 14 - Cardiovascular effects -- Introduction -- Disorders of cardiac rhythm -- Disorders of systemic blood pressure -- Congestive heart failure -- Myocardial toxicity -- Pulmonary hypertension -- Stroke and heart attack risk -- References -- Further reading -- Chapter 15 - Neurological disorders -- Introduction -- Headache -- Effects on the neuromuscular junction and myasthenia gravis -- Seizures -- Coma and encephalopathy -- Neuropathies -- Guillain-Barré syndrome -- Drug-induced movement disorders -- Sudden sleep onset with dopaminergic drugs -- References -- Chapter 16 - Sexual dysfunction and infertility -- Introduction -- Infertility -- Sexual dysfunction -- References -- Further reading -- Index.
• Sommario/riassunto: Adverse reactions to medicines continue to present a considerable burden on healthcare, causing considerable morbidity and mortality. As well as knowing about the benefits of medicines, healthcare professionals need to understand the problem of adverse drug reactions and be aware of how they can be prevented and managed. The new edition of this essential and practical guide has been extensively revised and updated.
• Titolo autorizzato: Adverse drug reactions
• ISBN: 0-85711-113-2
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910164945803321
• Lo trovi qui: Univ. Federico II