The organic chemistry of drug synthesis . Volume 7 / / Daniel Lednicer

• Pubblicazione: Hoboken, N.J. : , : John Wiley & Sons, , 2008
• Descrizione fisica: 1 online resource (xiii, 272 pages) : illustrations
• Disciplina: 547.2; 615/.19
• Soggetto topico: Pharmaceutical chemistry; Organic compounds - Synthesis
• Altri autori: LednicerDaniel <1929->
• Note generali: "Wiley-Interscience."
• Nota di contenuto: THE ORGANIC CHEMISTRY OF DRUG SYNTHESIS; CONTENTS; Preface; 1 OPEN-CHAIN COMPOUNDS; 1. Peptidomimetic Compounds; A. Antiviral Protease Inhibitors; 1. Human Immunodeficiency Virus; 2. Human Rhinovirus; 2. Miscellaneous Peptidomimetic Compounds; References; 2 ALICYCLIC COMPOUNDS; 1. Monocyclic Compounds; A. Prostaglandins; B. Antiviral Agents; C. Miscellaneous Monocyclic Compounds; 2. Polycyclic Compounds: Steroids; A. 19-Nor Steroids; B. Corticosteroid Related Compounds; 3. Polycyclic Compounds; References; 3 MONOCYCLIC AROMATIC COMPOUNDS; 1. Arylcarbonyl Derivatives; 2. Biphenyls ; 3. Compounds Related to Aniline 4. Compounds Related to Arylsulfonic Acids; 5. Diarylmethanes; 6. Miscellaneous Monocyclic Aromatic Compounds; References; 4 CARBOCYCLIC COMPOUNDS FUSED TO A BENZENE RING; 1. Indenes; 2. Naphthalenes; 3. Tetrahydronaphthalenes; 4. Other benzofused carbocyclic compounds; References; 5 FIVE-MEMBERED HETEROCYCLES; 1. Compounds with One Heteroatom; 2. Compounds with Two Heteroatoms; A. Oxazole and Isoxazoles; B. Imidazoles and a Pyrrazole; C. Thiazoles; D. Triazoles; E. Tetrazoles; References; 6 SIX-MEMBERED HETEROCYCLES; 1. Compounds with One Heteroatom ; A. PyridinesB. Reduced Pyridines; C. Miscellaneous; 2. Compounds with Two Heteroatoms; A. Pyrimidines; B. Miscellaneous Six-Membered Heterocycles; References; 7 FIVE-MEMBERED HETEROCYCLES FUSED TO ONE BENZENE RING; 1. Compounds with One Heteroatom; A. Benzofurans; B. Indoles; C. Indolones; D. Miscellaneous Compounds with One Heteroatom; 2. Five-Membered Rings with Two Heterocyclic Atoms; A. Benzimidazoles; B. Miscellaneous Compounds; References; 8 SIX-MEMBERED HETEROCYCLES FUSED TO ONE BENZENE RING; 1. Compounds with One Heteroatom; A. Benzopyrans; B. Quinolines and Their Derivatives ; C. Quinolone Antibacterial Agents 2. Compounds with Two Heteroatoms; A. Benzoxazines; B. Quinazolines; C. Miscellaneous Benzo-Fused Heterocycles; References; 9 BICYCLIC FUSED HETEROCYCLES; 1. Compounds with Five-Membered Rings Fused to Six-Membered Rings; A. Compounds with Two Heteroatoms; B. Compounds with Three Heteroatoms; C. Compounds with Four Heteroatoms; 2. Compounds with Two Fused Six-Membered Rings; 3. Miscellaneous Compounds with Two Fused Heterocyclic Rings: Beta Lactams; References; 10 POLYCYCLIC FUSED HETEROCYCLES; 1. Compounds with Three Fused Rings; 2. Compounds with Four Fused Rings 3. Compounds with Five or More Fused Rings: Camptothecins; References; Subject Index; Cross Index of Biological Activity; Cumulative Index
• Sommario/riassunto: The classic reference on the synthesis of medicinal agents --now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6.Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered.
• Titolo autorizzato: The organic chemistry of drug synthesis
• ISBN: 1-281-20373-4; 9786611203733; 0-470-18067-6; 0-470-18066-8
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910144290903321
• Lo trovi qui: Univ. Federico II
• Serie: Organic Chemistry Series of Drug Synthesis; ; 7