Lysosomes : biology, diseases, and therapeutics / / edited by Frederick R. Maxfield, James M. Willard, Shuyan Lu
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| Titolo: |
Lysosomes : biology, diseases, and therapeutics / / edited by Frederick R. Maxfield, James M. Willard, Shuyan Lu
|
| Pubblicazione: | Hoboken, New Jersey : , : Wiley, , 2016 |
| ©2016 | |
| Descrizione fisica: | 1 online resource (562 p.) |
| Disciplina: | 571.655 |
| Soggetto topico: | Lysosomes |
| Persona (resp. second.): | MaxfieldFrederick R. |
| WillardJames M. <1955-> | |
| LuShuyan <1971-> | |
| Note generali: | Description based upon print version of record. |
| Nota di bibliografia: | Includes bibliographical references at the end of each chapters and index. |
| Nota di contenuto: | Lysosomes an introduction / Frederick R. Maxfield -- Lysosome biogenesis and autophagy / Fulvio Reggiori, Judith Klumperman -- Multivesicular bodies: roles in intracellular and intercellular signalling / Emily R. Eden, Thomas Burgoyne, Clare E. Futter -- Lysosomes and mitophagy / Dominik Haddad, Patrik Verstreken -- Lysosome exocytosis and membrane repair / Rajesh K. Singh, Abigail S. Haka -- Role of lysosomes in lipid metabolism / Frederick R. Maxfield -- TFEB, master regulator of cellular clearance / Graciana Diez-Roux and Andrea Ballabio -- Lysosomal membrane permeabilization in cell death / Urska Repnik, Boris Turk -- The lysosome in aging-related neurodegenerative diseases / Ralph A. Nixon -- Lysosome and cancer / Marja Jaattela and Tuula Kallunki -- The genetics of sphingolipid hydrolases & sphingolipid storage diseases / Edward H. Schuchman and Calogera M. Simonaro -- Lysosome-related organelles : modifications of the lysosome paradigm / Adriana R. Mantegazza and Michael S. Marks -- Autophagy inhibition as a strategy for cancer therapy / Xiaohong Ma, Shengfu Piao, Quentin Mcafee, and Ravi K. Amaravadi -- Autophagy enhancers, are we there yet? / Shuyan Lu & Ralph A Nixon -- Pharmacological chaperones as potential therapeutics for lysosomal storage disorders: preclinical research to clinical studies / Robert E. Boyd, Elfrida R. Benjamin, Su Xu, Richie Khanna, and Kenneth J. Valenzano -- Endosomal escape pathways for delivery of biologics / Philip L. Leopold -- Lysosomes and antibody drug conjugates / Michelle Mack, Jennifer Kahler, Boris Shor, Michael Ritchie, Maureen Dougher, Matthew Sung, and Puja Sapra -- The mechanisms and therapeutic consequences of amine-containing drug sequestration in lysosomes / Nadia Hamid and Jeffrey P. Krise -- Lysosome dysfunction : an emerging mechanism of xenobiotic-induced toxicity / Shuyan Lu, Bart Jessen, Yvonne Will & Greg Stevens -- Lysosomes and phospholipidosis in drug development and regulation / James M. Willard and Albert De Felice. |
| Titolo autorizzato: | Lysosomes |
| ISBN: | 1-118-97831-5 |
| 1-118-97830-7 | |
| 1-118-97832-3 | |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910809185603321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |