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Antidepressants and receptor function [[electronic resource]]



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Titolo: Antidepressants and receptor function [[electronic resource]] Visualizza cluster
Pubblicazione: Chichester ; ; New York, : Wiley, 1986
Descrizione fisica: 1 online resource (306 p.)
Disciplina: 599.0182
616.85
616.8527061
Soggetto topico: Antidepressants - Physiological effect
Antidepressants - Receptors
Depression, Mental - Physiological aspects
Pharmacology, Experimental
Altri autori: PorterRuth  
BockGregory  
ClarkSarah  
Note generali: Editors: Ruth Porter, Gregory Bock (organizers) and Sarah Clark.
Proceedings of the Symposium on Depression, Antidepressants, and Receptor Sensitivity, held at the Ciba Foundation, London, 19-21 Nov. 1985.
"A Wiley-Interscience publication."
Nota di bibliografia: Includes bibliographies and indexes.
Nota di contenuto: ANTIDEPRESSANTS AND RECEPTOR FUNCTION; Contents; Participants; Introduction; Antidepressant-binding sites in brain and platelets; b-Adrenoceptor function in human adult skin fibroblasts: a study of manic- depressive illness; Genetic studies at the receptor level: investigations in human twins and experimental animals; Biochemical effects of antidepressant treat ment-studies of monoamine metabolites in cerebrospinal fluid and platelet [ 3H] imipramine binding; Platelet radioligand binding and neuroendocrine challenge tests in depression
How antidepressants work: cautionary conclusions based on clinical and laboratory studies of the longer-term consequences of antidepressant drug treatmentNeuroendocrine and other studies of the mechanism of antidepressant action of desipramine; Adrenergic and serotonergic receptor responsiveness in depression; General discussion I; Effect of repeated administration of clenbuterol on the regulation of b-adrenoceptors in the central nervous system of the rat; Depression in an animal model: focus on the locus ceruleus
Causes of changes in brain noradrenaline systems and later effects on responses to social stressors in rhesus monkeys: the cascade hypothesisEffects of chronically ad ministered antidepressants and elect roconvulsive treatment on cerebral neurotransmitter receptors in rodents with 'model depression'; The effects of electroconvulsive therapy and antidepressant drugs on monoamine receptors in rodent brain-similarities and differences; General discussion II; Closing remarks; Index of contributors; Subject index
Sommario/riassunto: Ciba Foundation Symposium 123 Antidepressants and Receptor Function Chairman: Dennis Murphy 1986 Depression is a common and often debilitating affective disorder. Attempts to develop effective antidepressants have a long history, but many questions remain about the mechanisms of action of such treatments and about the aetiology and pathophysiology of depression itself. Early observations centred attention on central monoamine systems, and animal studies suggested that changes in beta-adrenoceptor responsiveness were a common effect of antidepressant therapies. More recent research has encompas
Titolo autorizzato: Antidepressants and receptor function  Visualizza cluster
ISBN: 1-282-34607-5
9786612346071
0-470-51336-5
0-470-51337-3
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910830800203321
Lo trovi qui: Univ. Federico II
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Serie: Ciba Foundation symposium ; ; 123.