Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
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| Titolo: |
Acute exposure guideline levels for selected airborne chemicals [[electronic resource] /] / Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research Council
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| Pubblicazione: | Washington, D.C., : National Academy Press, c2002 |
| Descrizione fisica: | 1 online resource (292 p.) |
| Disciplina: | 615.9 |
| Soggetto topico: | Gases, Asphyxiating and poisonous |
| Hazardous substances - Environmental aspects | |
| Hazardous substances - Health aspects | |
| Chemicals - Physiological effect | |
| Chemicals - Health aspects | |
| Note generali: | Description based upon print version of record. |
| Nota di bibliografia: | Includes bibliographical references. |
| Nota di contenuto: | Acute Exposure Guideline Levels for Selected Airborne Chemicals -- Copyright -- OTHER REPORTS OF THE BOARD ON ENVIRONMENTAL STUDIES AND TOXICOLOGY -- Preface -- Contents -- Introduction -- SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING AEGLS -- Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances -- Appendix -- 1 Phosgene: Acute Exposure Guideline Levels -- SUMMARY -- 1. INTRODUCTION -- 2. HUMAN TOXICITY DATA -- 2.1. Acute Lethality -- 2.2. Nonlethal Toxicity -- 2.2.1. Case Reports -- 2.2.2. Epidemiologic Studies2.3. Developmental and Reproductive Toxicity -- 2.4. Genotoxicity -- 2.5. Carcinogenicity -- 2.6. Summary -- 3. ANIMAL TOXICITY DATA -- 3.1. Acute Lethality -- In Mouse, Rats, Guinea Pigs, Rabbits, Cats, Dogs, Goats, Sheep, Nonhuman Primates -- 3.2. Nonlethal Toxicity -- In Mice, Rats, Guinea Pigs, Hamsters, Rabbits, Dogs, Sheep, Goats, Cats, Monkeys -- 3.3. Developmental and Reproductive Toxicity -- 3.4. Genotoxicity -- 3.5. Carcinogenicity -- 3.6. Summary -- 4. SPECIAL CONSIDERATIONS -- 4.1. Metabolism and Disposition -- 4.2. Mechanism of Toxicity -- 4.3. Structure-Activity Relationships -- 4.4. Other Relevant Information -- 4.4.1. Haber's Law and Time Scaling -- 5. RATIONALE AND PROPOSED AEGL-1 -- 5.1. Human Data Relevant to AEGL-1 -- 5.2. Animal Data Relevant to AEGL-1 -- 5.3. Derivation of AEGL-1 -- 6. RATIONALE AND PROPOSED AEGL-2 -- 6.1. Human Data Relevant to AEGL-2 -- 6.2. Animal Data Relevant to AEGL-2 -- 6.3. Derivation of AEGL-2 -- 7. RATIONALE AND PROPOSED AEGL-3 -- 7.1. Human Data Relevant to AEGL-3 -- 7.2. Animal Data Relevant to AEGL-3 -- 7.3. Derivation of AEGL-3 -- 8. SUMMARY OF PROPOSED AEGLS -- 8.1. AEGL Values and Toxicity End Points -- 8.2. Comparison with Other Standards and Guidelines -- 8.3. Data Adequacy and Research Needs -- 9. REFERENCES -- Appendixes -- APPENDIX A DERIVATION OF AEGL VALUES -- Derivation of AEGL-1 -- Derivation of AEGL-2 -- Derivation of AEGL-3 -- APPENDIX B DERIVATION SUMMARY FOR ACUTE EXPOSURE GUIDELINE LEVELS FOR PHOSGENE (CAS No. 75-44-5) |
| Titolo autorizzato: | Acute exposure guideline levels for selected airborne chemicals |
| ISBN: | 0-309-18270-0 |
| 1-280-18330-6 | |
| 9786610183302 | |
| 0-309-56773-4 | |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910826825603321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |
Serie:
Compass series (Washington, D.C.)