Translational control of gene expression / / edited by Nahum Sonenberg, John W.B. Hershey, Michael B. Mathews

• Pubblicazione: Cold Spring Harbor, NY, : Cold Spring Harbor Laboratory Press, c2000
• Edizione: 2nd ed.
• Descrizione fisica: x, 1020 p. : ill. (some col.)
• Soggetto topico: Genetic translation
• Altri autori: SonenbergNahum HersheyJohn W. B MathewsMichael
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Intro -- Contents -- Preface -- Origins and Principles of Translational Control -- The Pathway and Mechanism of Initiation of Protein Synthesis -- The Protein Biosynthesis Elongation Cycle -- A Comparative View of Initiation Site Selection Mechanisms -- Mechanism and Regulation of Initiator Methionyl- tRNA Binding to Ribosomes -- Regulation of Ribosomal Recruitment in Eukaryotes -- Translational Control of Developmental Decisions -- Viral Translational Strategies and Host Defense Mechanisms -- Ribosomal Subunit Joining -- Physical and Functional Interactions between the mRNA Cap Structure and the Poly( A) Tail -- Translation Termination: ItÌs Not the End of the Story -- Genetic Approaches to Translation Initiation in Saccharomyces cerevisiae -- The Double-stranded RNA-activated Protein Kinase PKR -- Heme-regulated eIF2 Kinase -- PERK and Translational Control by Stress in the Endoplasmic Reticulum -- Regulation of Translation Initiation in Mammalian Cells by Amino Acids -- Translational Control during Heat Shock -- Translational Control by Upstream Open Reading Frames -- Cellular Internal Ribosome Entry Site Elements and the Use of cDNA Microarrays in Their Investigation -- Translational Control and Cancer -- Translational Control of Ferritin Synthesis -- Translational Control of TOP mRNAs -- S6 Phosphorylation and Signal Transduction -- Control of the Elongation Phase of Protein Synthesis -- Programmed Translational Frameshifting, Hopping, and Readthrough of TerminationCodons -- Recoding UGA as Selenocysteine -- Influence of Polyadenylation-induced Translation on Metazoan Development and Neuronal Synaptic Function -- Interaction of mRNA Translation and mRNA Degradation in Saccharomyces cerevisiae -- Destabilization of Nonsense-containing Transcripts in Saccharomyces cerevisiae. ; Nonsense-mediated RNA Decay in Mammalian Cells: A Splicing- dependent Means to Down- regulate the Levels of mRNAs That Prematurely Terminate Translation -- Translation Initiation on Picornavirus RNA -- Adenovirus Inhibition of Cellular Protein Synthesis and Preferential Translation of Viral mRNAs -- Reovirus Translational Control -- Translational Reprogramming during Influenza Virus Infection -- Translational Control in Poxvirus- infected Cells -- Nontranslational Functions of Components of the Translational Apparatus -- Index.
• Titolo autorizzato: Translational control of gene expression
• ISBN: 0-87969-676-1
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910822436803321
• Lo trovi qui: Univ. Federico II
• Serie: Cold Spring Harbor monograph series ; ; 39.