Translational research in genetics and genomics / / Moyra Smith

• Autore: Smith Moyra
• Pubblicazione: Oxford ; ; New York, : Oxford University Press, 2008
• Edizione: 1st ed.
• Descrizione fisica: xiv, 220 p. : ill
• Disciplina: 616/.042
• Soggetto topico: Medical genetics; Genomics
• Note generali: Previously issued in print: 2008.
• Nota di bibliografia: Includes bibliographical references (p. 179-206) and index.
• Nota di contenuto: Intro -- Contents -- 1. Isolation of Disease Genes Through Genomics -- 2. Advances in Genome Analysis: Discovery of Structural Variation and Genomic Dosage Differences in Health and Disease -- 3. Significance of DNA Sequence Changes for Diagnosis and Therapy -- 4. Epigenetics -- 5. Complex Diseases: Molecular Genetic Contributions to Elucidation of Etiopathogenesis of Late-Onset Neurodegenerative Diseases -- 6. Advances in Treatment of Single Gene Disorders Through Translational Science: Treatment With Small Molecules (Chaperones) and Gene-Based Therapies -- 7. From Gene Discovery in Genetic Syndromes to Identification of Therapeutic Agents -- 8. Impact of the Environment on the Genome -- 9. Molecular Defects in Cancer: Application to Therapy -- 10. Pharmacogenetics and Pharmacogenomics -- 11. Phenomes, Phenotypes, and Clinical Genetic Services -- References -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- R -- S -- T -- U -- V -- W -- X -- Y.
• Titolo autorizzato: Translational research in genetics and genomics
• ISBN: 0-19-029531-7; 0-19-770912-5; 1-282-54418-7; 9786612544187; 0-19-971834-2
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910823405303321
• Lo trovi qui: Univ. Federico II
• Serie: Oxford scholarship online.