Alzheimer's disease [[electronic resource] ] : advances in etiology, pathogenesis and therapeutics / / edited by Khalid Iqbal, Sangram S. Sisodia, Bengt Winblad

• Pubblicazione: Chichester ; ; New York, : Wiley, c2001; [Bethesda, Md.] : , : U.S. Dept. of Health and Human Services, National Institutes of Health, Alzheimer's Disease Education & Referral Center, , [2011]
• Descrizione fisica: 1 online resource (890 p.)
• Disciplina: 616.831
• Soggetto topico: Alzheimer's disease
• Soggetto genere / forma: Online resources.; Popular works.
• Altri autori: IqbalKhalid SisodiaSangram S WinbladBengt
• Note generali: Papers presented at the 7th International Conference on Alzheimer's Disease and Related Disorders, held in Washington, D.C., in July 2000.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Alzheimer's Disease ADVANCES IN ETIOLOGY, PATHOGENESIS AND THERAPEUTICS; Contents; List of Contributors; Dedications; Scientists Honored for Pioneering Research; Preface; Acknowledgments; I. EPIDEMIOLOGY AND RISK FACTORS; 1. The Transition from Normal Functioning to Dementia in the Aging Population; 2. Epidemiology of Alzheimer's Disease and Dementia: Advances and Challenges; 3. Epidemiology of Dementia in Down's Syndrome; II. GENETICS; 4. A Genomic Search for Alzheimer's Disease Genes ; 5. Candidate Genes Showing No Evidence of Association with Alzheimer's Disease: Results of the NIMH-AD Genetics Initiative6. Familial Alzheimer's Disease with Spastic Paraparesis Associated with a Mutation at Codon 261 of the Presenilin 1 Gene; 7. Genetic Analysis of the Presenilin Pathway in Drosophila; 8. Molecular Genetics and Transgenic Modeling of the Tauopathies; 9. Regulation of Four-repeat tau Expression: Interactions between Exon and Intron Splicing Regulatory Sequences; III. DIAGNOSIS AND CLINICAL COURSE ; 10. Preclinical Prediction of AD: Relation Between Neuropsychological and Neuroimaging Findings11. Neuropsychological Detection of Preclinical Alzheimer's Disease: Results of a Neuropathological Series of 'Normal' Controls; 12. Potentially Reversible Conditions in Memory Clinic Patients; 13. The Alzheimer's Disease Centers' Neuropsychological Database Initiative: A Resource for Alzheimer's Disease Prevention Trials; 14. Mild Cognitive Impairment: Transition from Aging to Alzheimer's Disease; 15. Brain Functional Imaging in Early and Preclinical Alzheimer's Disease ; 16. Amyloid, PHF-tau, Ubiquitin and Synaptic Markers in the Progression of Alzheimer's Disease: Immunochemical Analyses of Frontal Cortex from Prospectively Studied Elderly Humans17. Imaging the Consequences of Alzheimer's Disease Pathology; 18. Influence of apoE Genotype and PET Brain Imaging on Preclinical Prediction of Alzheimer's Disease; 19. Overview of Vascular Dementia; 20. Clinical and Imaging Characteristics of Vascular Dementia in a Memory Clinic; 21. MRI of Entorhinal Cortex and Hippocampus in Alzheimer's Disease, Subcortical Ischemic Vascular Dementia and Mixed Dementia ; 22. Olfactory Function and Event-related Potentials in Alzheimer's Disease23. Phenotypic Differences in Cholinergic Markers within the Nucleus Basalis in Individuals with Mild Cognitive Impairment; 24. Evaluating CNS Biomarkers for Alzheimer's Disease; 25. CSF Markers for Early Alzheimer's Disease; 26. CSF-Phospho-tau (181P) as a Promising Marker for Discriminating Alzheimer's Disease from Dementia with Lewy Bodies; 27. Increased Levels of a Minor Glycoform of Acetylcholinesterase in Alzheimer's Disease Brain and Cerebrospinal Fluid ; 28. Plasma b-Amyloid as a Surrogate Genetic Marker in Late-onset Alzheimer's Disease
• Sommario/riassunto: Alzheimer's Disease is an ever present problem affecting millions of people around the world and, as people's average lifespan lengthens, its prevalence is set to increase. A global effort is needed to combat the disease, including research to investigate the causes, development of effective treatments and, ultimately, prevention of the disease. Published every two years, these timely books discuss the very latest research. This new volume provides a unique source of reference to the important work being done in this field, it gives academics and clinicians an opportunity to learn abo
• Titolo autorizzato: Alzheimer's disease
• ISBN: 1-280-10126-1; 9786610101269; 0-470-85174-0; 0-470-84645-3
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910678020603321
• Lo trovi qui: Univ. Federico II