Cardio-oncology : management of toxicities in the era of immunotherapy / / Antonio Russo [and three others], editors

• Pubblicazione: Cham, Switzerland : , : Springer Nature Switzerland AG, , [2022]; ©2022
• Descrizione fisica: 1 online resource (127 pages) : illustrations
• Disciplina: 616.994061
• Soggetto topico: Cancer - Immunotherapy; Cardiovascular toxicology
• Persona (resp. second.): RussoAntonio
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Intro -- Foreword -- Preface -- Acknowledgments -- Contents -- Contributors -- 1: Background: Immunology and Cancer -- References -- 2: Available Immunotherapy Drugs in Oncology -- Anti-PD-1 Agents -- Pembrolizumab -- Nivolumab -- Anti-PD-L1 Agents -- Atezolizumab -- Durvalumab -- Avelumab -- Anti-CTLA4 Agents -- Ipilimumab -- References -- 3: Immunotherapy Adverse Events -- Introduction -- Myocarditis -- Noninflammatory Myocardial Dysfunction -- Arrhythmias -- Pericardial Disease -- Vasculitis -- Myocardial Infarction -- References -- 4: Pathophysiology of Cardiac Toxicity -- Pathophysiology of Cardiac Toxicity: An Overview -- Cardiac Dysfunction and Heart Failure -- Vascular Disease -- Arrhythmias -- Pericardial and Valvular Disease -- References -- 5: Cardiac Risk Factors for Immunotherapy -- Why Evaluate the Cardiovascular Risk in Oncological Patients Who Have Undergone Immunotherapy? -- How to Quantify Cardiovascular Risk? -- Experimental Preventive Strategies for Immune Checkpoint Inhibitor (ICI)-Induced Cardiotoxicity: Evidence and Perspectives -- References -- 6: Diagnostic Methods of Cardiac Immunotherapy Damaging -- Introduction -- Clinical and Electrocardiographic Evaluation -- Echocardiography -- Myocardial Deformation Imaging -- Nuclear Imaging and Cardiac Magnetic Resonance -- Role of Biomarkers -- Role of Endomyocardial Biopsy -- Diagnostic Approach -- Conclusion -- References -- 7: Biomarkers of Early Cardiotoxicity -- Introduction -- Cardiac Troponins -- Brain Natriuretic Peptides -- New Emerging Biomarkers -- Conclusion -- References -- 8: Management of Patients with Cardiac Toxicity: The Point of View of the Cardiologist -- Introduction -- Atherosclerosis and Cardiovascular Events -- Myocarditis and Heart Failure -- Clinical Presentation -- Diagnosis -- Management -- ICI-Associated Pericarditis -- Diagnosis -- Management. ; Takotsubo Syndrome -- Arrhythmias -- Management -- Immunotherapy-Associated Vasculitis -- Immunotherapy-Associated Thromboembolism -- Screening and Surveillance -- Conclusion -- References -- 9: Management of Patients with Cardiac Toxicity: The Point of View of the Oncologist -- Introduction -- Mechanisms of Action of Cardiovascular ICI Adverse Events -- Myocarditis -- Epidemiology -- Physiopathology -- Clinical Presentation -- Laboratory and Imaging Findings -- Diagnosis and Management -- Pericarditis -- Epidemiology -- Pathophysiology -- Clinical Presentation -- Diagnosis -- Management -- Acute Coronary Syndrome (ACS) and Myocardial Infarction (MI) -- Epidemiology -- Physiopathology -- Clinical Presentation -- Diagnosis -- Management -- Takotsubo Cardiomyopathy -- Epidemiology -- Pathophysiology -- Clinical Presentation -- Diagnosis -- Management -- Dysrhythmias -- Epidemiology -- Pathophysiology -- Diagnosis -- Management -- Vasculitis -- Epidemiology -- Pathophysiology -- Clinical Presentation -- Diagnosis -- Management -- Cardiotoxicity Related to New Immunotherapy (CAR T Cell) -- Epidemiology -- Pathophysiology -- Diagnosis -- Management -- Baseline Assessment and General Principle of Management for Cardiovascular IRAE -- Conclusion -- References -- 10: Future Perspectives -- Introduction -- Basic and Translational Research -- Clinical Research -- Education and Training -- Service Organization and Provision -- References -- Index.
• Titolo autorizzato: Cardio-Oncology
• ISBN: 3-030-97744-7
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910586574503321
• Lo trovi qui: Univ. Federico II
• Serie: Current clinical pathology.