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Drugs Targeting B-Cells in Autoimmune Diseases / / edited by Xavier Bosch, Manuel Ramos-Casals, Munther A Khamashta



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Titolo: Drugs Targeting B-Cells in Autoimmune Diseases / / edited by Xavier Bosch, Manuel Ramos-Casals, Munther A Khamashta Visualizza cluster
Pubblicazione: Basel : , : Springer Basel : , : Imprint : Springer, , 2014
Edizione: 1st ed. 2014.
Descrizione fisica: 1 online resource (300 p.)
Disciplina: 616.978
616.978061
Soggetto topico: Pharmacology
Immunology
Rheumatology
Internal medicine
Pharmacology/Toxicology
Internal Medicine
Persona (resp. second.): BoschXavier
Ramos-CasalsManuel
KhamashtaMunther A
Note generali: Description based upon print version of record.
Nota di bibliografia: Includes bibliographical references and index.
Nota di contenuto: Historic outline of the development of drugs targeting B-cells -- Understanding B-cell biology -- Pharmacological effects and mechanisms of action of agents blocking B cells -- Systemic lupus erythematosus: direct B-cell blocking -- Systemic lupus erythematosus: indirect B-cell blocking -- B-cell targeted therapies in rheumatoid arthritis -- B-cell targeted therapies in Primary Sjögren Syndrome -- Targeting B cells in ANCA-associated vasculitis -- B-cell targeted therapies in systemic sclerosis and inflammatory myopathies -- B-cell targeted therapies in cryoglobulinemia -- B-cell targeted therapies in autoimmune cytopenias and thrombosis -- Targeting B cells in neurological autoimmune diseases -- Targeting B cells in other systemic autoimmune diseases -- Safety of B-cell targeted therapies -- The future potential of biosimilars targeting B-cells.
Sommario/riassunto: This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell targeted therapy may be indicated are identified, thereby offering comprehensive support for therapeutic decisions on the basis of the latest published evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases.
Titolo autorizzato: Drugs Targeting B-Cells in Autoimmune Diseases  Visualizza cluster
ISBN: 3-0348-0706-6
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910298324403321
Lo trovi qui: Univ. Federico II
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Serie: Milestones in Drug Therapy, . 2296-6056