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Titolo: | Drugs Targeting B-Cells in Autoimmune Diseases / / edited by Xavier Bosch, Manuel Ramos-Casals, Munther A Khamashta |
Pubblicazione: | Basel : , : Springer Basel : , : Imprint : Springer, , 2014 |
Edizione: | 1st ed. 2014. |
Descrizione fisica: | 1 online resource (300 p.) |
Disciplina: | 616.978 |
616.978061 | |
Soggetto topico: | Pharmacology |
Immunology | |
Rheumatology | |
Internal medicine | |
Pharmacology/Toxicology | |
Internal Medicine | |
Persona (resp. second.): | BoschXavier |
Ramos-CasalsManuel | |
KhamashtaMunther A | |
Note generali: | Description based upon print version of record. |
Nota di bibliografia: | Includes bibliographical references and index. |
Nota di contenuto: | Historic outline of the development of drugs targeting B-cells -- Understanding B-cell biology -- Pharmacological effects and mechanisms of action of agents blocking B cells -- Systemic lupus erythematosus: direct B-cell blocking -- Systemic lupus erythematosus: indirect B-cell blocking -- B-cell targeted therapies in rheumatoid arthritis -- B-cell targeted therapies in Primary Sjögren Syndrome -- Targeting B cells in ANCA-associated vasculitis -- B-cell targeted therapies in systemic sclerosis and inflammatory myopathies -- B-cell targeted therapies in cryoglobulinemia -- B-cell targeted therapies in autoimmune cytopenias and thrombosis -- Targeting B cells in neurological autoimmune diseases -- Targeting B cells in other systemic autoimmune diseases -- Safety of B-cell targeted therapies -- The future potential of biosimilars targeting B-cells. |
Sommario/riassunto: | This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell targeted therapy may be indicated are identified, thereby offering comprehensive support for therapeutic decisions on the basis of the latest published evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases. |
Titolo autorizzato: | Drugs Targeting B-Cells in Autoimmune Diseases |
ISBN: | 3-0348-0706-6 |
Formato: | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910298324403321 |
Lo trovi qui: | Univ. Federico II |
Opac: | Controlla la disponibilità qui |