Current concepts in uveal melanoma / / volume editors, Martine J. Jager ... [et al.]

• Pubblicazione: Basel, : Karger, 2012
• Descrizione fisica: 1 online resource (196 p.)
• Disciplina: 616.99/477
• Soggetto topico: Melanoma - Treatment; Uvea - Diseases - Treatment; Melanoma - Diagnosis; Uvea - Diseases - Diagnosis
• Altri autori: JagerMartine
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: ""Cover""; ""Contents""; ""List of Contributors""; ""Preface""; ""Diagnosis of Uveal Melanoma""; ""Abstract""; ""Diagnosing Large to Medium- Sized Uveal Melanomas""; ""Diagnosing Small Uveal Melanomas""; ""References""; ""Treatment Selection for Uveal Melanoma""; ""Abstract""; ""Clinical Scenarios""; ""Method of Treatment Selection""; ""Summary and Conclusions""; ""References""; ""Ruthenium-106 Brachytherapy""; ""Abstract""; ""The Ru-106 Applicator""; ""The Use of Ru-106 Applicators for Uveal Melanoma""; ""Results of Ru-106 Brachytherapy""; ""Ru-106 Brachytherapy for Iris Melanoma"" ; ""Combined Use of Ru-106 Brachytherapy with Other Treatment Modalities""""Conclusions""; ""References""; ""Treatment of Uveal Melanoma by Accelerated Proton Beam""; ""Abstract""; ""Technique of Proton Beam Therapy for Uveal Melanoma""; ""Indications""; ""Evolution of the Tumor following Proton Beam Irradiation""; ""Follow-Up of Patients""; ""Results of Proton Beam Therapy""; ""Additional Treatments""; ""Conclusion""; ""Acknowledgement""; ""References""; ""Stereotactic Photon Beam Irradiation of Uveal Melanoma""; ""Abstract""; ""Gamma Knife""; ""Cyberknife""; ""Linear Accelerator"" ; ""Discussion""""Acknowledgment""; ""References""; ""Local Resection of Uveal Melanoma""; ""Abstract""; ""Iridectomy""; ""Iridocyclectomy""; ""Choroidectomy""; ""Endoresection""; ""Discussion""; ""Conclusions""; ""References""; ""Biopsies in Uveal Melanoma""; ""Abstract""; ""Diagnostic Intraocular Tumor Biopsy: Indications""; ""Intraocular Tumor Biopsy: Contraindications""; ""Intraocular Tumor Biopsy: Techniques""; ""Safety""; ""Biopsy for Cytogenetic Analysis""; ""Heterogeneity""; ""Conclusion""; ""References""; ""Analysis of Intraocular Biopsies""; ""Abstract"" ; ""Sample Handling and Processing""""Examination of Anterior Segment Samples""; ""Examination of Choroidal Samples""; ""Prognostication and Intraocular Biopsies""; ""Examination of Vitreous Samples""; ""Non-Diagnostic Intraocular Biopsy""; ""Conclusions""; ""Acknowledgements""; ""References""; ""Anti-Angiogenic Therapy in Uveal Melanoma""; ""Abstract""; ""Tumor Angiogenesis in Uveal Melanoma""; ""The Role of Vascular Endothelial Growth Factor""; ""Approved Anti-Angiogenic Treatment in Cancer""; ""Anti-Angiogenic Therapy in Uveal Melanoma""; ""Adverse Effects of Anti-Angiogenic Therapy"" ; ""Conclusion""""References""; ""Immunotherapy of Uveal Melanoma""; ""Abstract""; ""Protective Antitumor Immune Responses Capitalize on Adaptive Immunity by Tumor- Specific T Cells""; ""Uveal Melanoma-Induced Immune Suppression Is a Hurdle to Overcome""; ""Adapting Immunotherapy of Cutaneous Melanoma for Treatment of Uveal Melanoma""; ""Therapeutic and Prophylactic Immunotherapy for Uveal Melanoma""; ""Acknowledgements""; ""Disclosure Statement""; ""References""; ""Genetic Determinants of Uveal Melanoma""; ""Abstract""; ""Predisposition to Uveal Melanoma"" ; ""Genomic Abnormalities in Uveal Melanoma""
• Sommario/riassunto: Uveal melanoma is an aggressive form of cancer that can involve the iris, the ciliary body, and/or the choroid, which is the main location of this tumor. Patients often wish to be informed about treatment choices and the results of different approaches. Important current clinical questions are whether a biopsy should be taken of choroidal melanomas, what should be done with this biopsy, and whether high-risk patients should be screened regularly. This volume describes the clinical characteristics of uveal melanoma along with the different current techniques available for treatment, such as radioactive plaque treatment, proton beam therapy, and local tumor resection. Furthermore, techniques for taking biopsies and characterizing biopsy material are demonstrated. Future therapies such as anti-VEGF treatment and options for the treatment of metastases are also discussed. Residents with an interest in ocular oncology, ophthalmologists or physicians dealing with uveal melanoma, as well as patients wishing to know more about this malignancy will find a topical update on uveal melanoma in this publication.
• Titolo autorizzato: Current concepts in uveal melanoma
• ISBN: 3-8055-9791-6
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910163131403321
• Lo trovi qui: Univ. Federico II
• Serie: Developments in ophthalmology ; ; v. 49.