Gene family targeted molecular design [[electronic resource] /] / edited by Karen E. Lackey
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| Titolo: |
Gene family targeted molecular design [[electronic resource] /] / edited by Karen E. Lackey
|
| Pubblicazione: | Hoboken, N.J., : John Wiley & Sons, c2009 |
| Descrizione fisica: | 1 online resource (382 p.) |
| Disciplina: | 615/.7 |
| Soggetto topico: | Pharmacogenomics |
| Drugs - Design | |
| Altri autori: |
LackeyKaren
|
| Note generali: | Description based upon print version of record. |
| Nota di bibliografia: | Includes bibliographical references and index. |
| Nota di contenuto: | Drug discoveries by gene family / Karen E. Lackey -- G-protein coupled receptors / Stephen L. Garland and Tom D. Heightman -- Ion channels gene family : strategies for discovering ion channel drugs / Maria L. Garcia and Gregory J. Kaczorowski -- Integrins / David D. Miller -- Strategies for discovering kinase drugs / Jerry L. Adams ... [et al.] -- Protease-directed drug discovery / Richard Sedrani, Ulrich Hommel, and Jor̈g Eder -- Small-molecule inhibitors of protein-protein interactions : challenges and prospects / Adrian Whitty -- Transporters / Anne Hersey, Frank E. Blaney, and Sandeep Modi -- Nuclear receptor drug discovery / Hiroyuki Kagechika and Aya Tanatani -- Summary and comparison of molecules designed to modulate druggable targets in the major gene families / Karen E. Lackey. |
| Sommario/riassunto: | As research progresses and information continues to proliferate in the field of molecular design for therapeutic use, there is a need for a reference that brings current theory and proven practice together in a how-to volume. This reference guides scientists new to the field on how to design small molecules that interact with critical protein targets. The chapters condense useful material into a manageable format which is carefully organized and presented. It offers an essential resource for a variety of chemists in academia, and the biotech and pharmaceutical industries, as well as profession |
| Titolo autorizzato: | Gene family targeted molecular design |
| ISBN: | 1-282-68586-4 |
| 9786612685866 | |
| 0-470-42393-5 | |
| 0-470-42392-7 | |
| Formato: | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione: | Inglese |
| Record Nr.: | 9910144392803321 |
| Lo trovi qui: | Univ. Federico II |
| Opac: | Controlla la disponibilità qui |