X & Y chromosomal variations : hormones, brain development, and neurodevelopmental performance / / Carole A. Samango-Sprouse, Andrea L. Gropman

• Autore: Samango-Sprouse Carole A.
• Pubblicazione: [San Rafael, California] : , : Morgan & Claypool Life Sciences, , 2017; ©2017
• Descrizione fisica: 1 online resource (138 pages) : color illustrations
• Disciplina: 572.87
• Soggetto topico: Sex chromosomes; Sex chromosome abnormalities
• Soggetto genere / forma: Electronic books.
• Persona (resp. second.): GropmanAndrea L.
• Note generali: Series from website.; Part of: Colloquium digital library of life sciences.
• Nota di bibliografia: Includes bibliographical references.
• Nota di contenuto: Dedication -- Acknowledgments -- 1. Introduction -- 2. Meiosis and mitosis -- 3. Testosterone and 47, XXY: 3.1. Testosterone and XXY; 3.2. Summary -- 4. Endocrinological issues and hormonal manipulation in children and men with Klinefelter syndrome: 4.1. Introduction; 4.2. Materials and methods; 4.3. Results; 4.4. Future developments; 4.5. Conclusion; 4.6. Acknowledgments -- 5. Neurological functioning in 47, XXY: 5.1. Brain development; 5.2. Neurological examination in boys with XXY; 5.3. Cognitive profile; 5.4. Psychiatric disorders and X chromosome disorders; 5.5. Summary -- 6. Neuroimaging in XY chromosomal disorders: 6.1. Neuroimaging; 6.2. Gender differences in brain development; 6.3. 47, XXY and neuroimaging findings; 6.4. Epigenetic and genetic influences on brain development; 6.5. 47, XXX and neuroimaging findings; 6.6. Neuroimaging findings and XYY; 6.7. 49, XXXXY and neuroimaging findings; 6.8. The extra X vs. the extra Y; 6.9. Conclusions -- 7. The evolving perspective on X and Y chromosomal disorders: 7.1. Early international studies; 7.2. Growth; 7.3. Motor development; 7.4. Speech and language; 7.5. Temperament; 7.6. Conclusion -- 8. Infant development in X and Y chromosomal disorders: 8.1. Progression of neuromotor skills; 8.2. Symmetry and movement; 8.3. Timing of physical therapy; 8.4. Speech and language development; 8.5. Speech and language dysfunction: symptoms of XY chromosomal disorder; 8.6. Temperament; 8.7. Summary -- ; 9. Phenotype and developmental progression of X and Y chromosomal variations: 9.1. 47, XXY; 9.2. ADHD; 9.3. Reading function; 9.4. Speech and language; 9.5. Biological treatment; 9.6. Behavioral issues; 9.7. 47, XYY; 9.8. 47, XXX; 9.9. Summary of developmental progression in X and Y chromosomal disorders -- 10. Social language in X and Y chromosomal variations: 10.1. Introduction; 10.2. Social language and cognition within autistic diagnoses; 10.3. 47, XXX (Triple X, Trisomy X); 10.4. 48, XXXX (Tetra X); 10.5. Social language development in variant forms of XY chromosomal disorders; 10.6. Conclusions for communication improvement in children with XY variants; 10.7. The social profile of 47, XXY; 10.8. The social profile of 47, XYY; 10.9. Conclusions for 47, XXY and 47, XYY -- 11. Conclusions -- References -- Author biographies.
• Sommario/riassunto: This is the first book on X and Y chromosomal disorders to address these common but rarely diagnosed conditions. This book seeks to present the latest in research and clinical care addressing neuroimaging, the interaction between hormones, brain development, and neurodevelopmental progression. This book will primarily focus on 47, XXY (Klinefelter syndrome, or KS), 47, XYY (Jacobs' syndrome), and 47, XXX (Triple X). More variant disorders such as 48, XXXX, 48, XXXY and 49, XXXXY will be discussed. Topics of interest include neurological functioning, neuroimaging, social language, and the evolving perspectives of these XY chromosomal disorders. The effects of testosterone supplementation in males with 47, XXY will also be examined.
• Titolo autorizzato: X & Y chromosomal variations
• ISBN: 1-61504-691-7
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910136208203321
• Lo trovi qui: Univ. Federico II
• Serie: Colloquium series on the developing brain ; ; Number 13.