Molecular diagnostics : the key driver in personalized cancer medicine / / editors, Jan Trost Jorgensen, Henrik Winther

• Pubblicazione: Singapore, : Pan Stanford Pub., ©2010
• Descrizione fisica: 1 online resource (359 p.)
• Disciplina: 616.0756
• Soggetto topico: Molecular diagnosis; Genetic screening; Cancer - Diagnosis
• Altri autori: JørgensenJan Trøst WintherHenrik
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical referneces and index.
• Nota di contenuto: Cover; CONTENTS; Introduction; Developing Molecular Diagnostics in Cancer; The Estrogen and Progesterone Receptors - Setting the Scene for Pharmacodiagnostics; The Development of the HercepTestTM - From Bench to Bedside; Predictive Biomarkers and Translational Cancer Medicine; Pharmacodiagnostic Testing - Immunohistology; In Situ Hybridisation for Pharmacodiagnostic Testing; MammaPrint® Translating Research into a Diagnostic Test; DNA Biomarkers in the Diagnosis and Management of Cancer; Validating the Analytical Power and Parameters of an Immunohistochemical Test ; Drug and Pharmacodiagnostic Co-Development: Statistical ConsiderationsClinical Validation of Biomarkers in Cancer; Pharmacogenomic Markers for Cancer Therapy; Safety and Effective Biomakers in Oncology - A Regulatory Drug and Device Perspective; Personalizing Treatment Selection for Breast Cancer; Pharmacodiagnostics and Personalized Medicine in Cancer; Index
• Sommario/riassunto: Provides an overview of molecular cancer diagnostic assays, which are the prerequisites for optimal solutions within personalized cancer medicine. This book offers definitions of the pharmacodiagnostic concept, and historical perspectives of the early steps into molecular cancer diagnostics linked to therapy.
• Titolo autorizzato: Molecular diagnostics
• ISBN: 0-429-53369-1; 0-429-06650-3; 981-4241-45-8
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910792405803321
• Lo trovi qui: Univ. Federico II