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Titolo: | Cardio-oncology : management of toxicities in the era of immunotherapy / / Antonio Russo [and three others], editors |
Pubblicazione: | Cham, Switzerland : , : Springer Nature Switzerland AG, , [2022] |
©2022 | |
Descrizione fisica: | 1 online resource (127 pages) : illustrations |
Disciplina: | 616.994061 |
Soggetto topico: | Cancer - Immunotherapy |
Cardiovascular toxicology | |
Persona (resp. second.): | RussoAntonio |
Nota di bibliografia: | Includes bibliographical references and index. |
Nota di contenuto: | Intro -- Foreword -- Preface -- Acknowledgments -- Contents -- Contributors -- 1: Background: Immunology and Cancer -- References -- 2: Available Immunotherapy Drugs in Oncology -- Anti-PD-1 Agents -- Pembrolizumab -- Nivolumab -- Anti-PD-L1 Agents -- Atezolizumab -- Durvalumab -- Avelumab -- Anti-CTLA4 Agents -- Ipilimumab -- References -- 3: Immunotherapy Adverse Events -- Introduction -- Myocarditis -- Noninflammatory Myocardial Dysfunction -- Arrhythmias -- Pericardial Disease -- Vasculitis -- Myocardial Infarction -- References -- 4: Pathophysiology of Cardiac Toxicity -- Pathophysiology of Cardiac Toxicity: An Overview -- Cardiac Dysfunction and Heart Failure -- Vascular Disease -- Arrhythmias -- Pericardial and Valvular Disease -- References -- 5: Cardiac Risk Factors for Immunotherapy -- Why Evaluate the Cardiovascular Risk in Oncological Patients Who Have Undergone Immunotherapy? -- How to Quantify Cardiovascular Risk? -- Experimental Preventive Strategies for Immune Checkpoint Inhibitor (ICI)-Induced Cardiotoxicity: Evidence and Perspectives -- References -- 6: Diagnostic Methods of Cardiac Immunotherapy Damaging -- Introduction -- Clinical and Electrocardiographic Evaluation -- Echocardiography -- Myocardial Deformation Imaging -- Nuclear Imaging and Cardiac Magnetic Resonance -- Role of Biomarkers -- Role of Endomyocardial Biopsy -- Diagnostic Approach -- Conclusion -- References -- 7: Biomarkers of Early Cardiotoxicity -- Introduction -- Cardiac Troponins -- Brain Natriuretic Peptides -- New Emerging Biomarkers -- Conclusion -- References -- 8: Management of Patients with Cardiac Toxicity: The Point of View of the Cardiologist -- Introduction -- Atherosclerosis and Cardiovascular Events -- Myocarditis and Heart Failure -- Clinical Presentation -- Diagnosis -- Management -- ICI-Associated Pericarditis -- Diagnosis -- Management. |
Takotsubo Syndrome -- Arrhythmias -- Management -- Immunotherapy-Associated Vasculitis -- Immunotherapy-Associated Thromboembolism -- Screening and Surveillance -- Conclusion -- References -- 9: Management of Patients with Cardiac Toxicity: The Point of View of the Oncologist -- Introduction -- Mechanisms of Action of Cardiovascular ICI Adverse Events -- Myocarditis -- Epidemiology -- Physiopathology -- Clinical Presentation -- Laboratory and Imaging Findings -- Diagnosis and Management -- Pericarditis -- Epidemiology -- Pathophysiology -- Clinical Presentation -- Diagnosis -- Management -- Acute Coronary Syndrome (ACS) and Myocardial Infarction (MI) -- Epidemiology -- Physiopathology -- Clinical Presentation -- Diagnosis -- Management -- Takotsubo Cardiomyopathy -- Epidemiology -- Pathophysiology -- Clinical Presentation -- Diagnosis -- Management -- Dysrhythmias -- Epidemiology -- Pathophysiology -- Diagnosis -- Management -- Vasculitis -- Epidemiology -- Pathophysiology -- Clinical Presentation -- Diagnosis -- Management -- Cardiotoxicity Related to New Immunotherapy (CAR T Cell) -- Epidemiology -- Pathophysiology -- Diagnosis -- Management -- Baseline Assessment and General Principle of Management for Cardiovascular IRAE -- Conclusion -- References -- 10: Future Perspectives -- Introduction -- Basic and Translational Research -- Clinical Research -- Education and Training -- Service Organization and Provision -- References -- Index. | |
Titolo autorizzato: | Cardio-Oncology |
ISBN: | 3-030-97744-7 |
Formato: | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione: | Inglese |
Record Nr.: | 9910586574503321 |
Lo trovi qui: | Univ. Federico II |
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