Parasitic nematodes : molecular biology, biochemistry and immunology / / edited by Malcolm W. Kennedy and William Harnett

• Pubblicazione: Oxfordshire, England ; ; Boston, Massachusetts : , : CABI, , 2013; ©2013
• Edizione: 2nd ed.
• Descrizione fisica: 1 online resource (446 p.)
• Disciplina: 592.57
• Soggetto topico: Nematodes
• Persona (resp. second.): HarnettW (William); KennedyM. W (Malcolm W.)
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
• Nota di contenuto: ""Contents""; ""Contributors""; ""Preface""; ""Access to Colour Illustrations""; ""Cover Illustrations""; ""Acknowledgement""; ""PART I: EVOLUTION OF PARASITISM AND LIFE HISTORY ADAPTATIONS""; ""1. The Genome of Pristionchus pacificus and the Evolution of Parasitism""; ""Introduction""; ""Theoretical Considerations""; ""Life-history Adaptations""; ""P. pacificus as a Case Study""; ""Adaptations I: Genome Evolution""; ""Adaptations II: Nematodeâ€?Insect Interactions""; ""Adaptations III: Evolution of Dauer Formation""; ""Adaptations IV: Regulation of Mouth-form Dimorphism"" ; ""Concluding Remarks""""References""; ""2. Life-history Plasticity and Responses to Host Defence""; ""General Principles""; ""Phenotypic Plasticity: Some Conceptual Issues""; ""Helminth Life-history Trait Variation""; ""Helminth Life-history Trait Plasticity""; ""Analogies with Life-history Traits of Free-living Nematodes""; ""Helminth Life-history Trait Plasticity: Inside Hosts""; ""Evolution of Helminth Life-history Traits""; ""Conclusion""; ""References""; ""3. The Complex Armoury of Plant-parasitic Nematodes""; ""Introduction"" ; ""An Exposition of Our Protagonists, and an Introduction to Some Terminology""""The Molecular Basis for Parasitism by PPN""; ""Conclusions""; ""References""; ""4. Innate Immunity in Caenorhabditis elegans and Other Nematodes""; ""Introduction""; ""The life Cycle and Natural Habitat of Six Nematode Species""; ""Immune Response in C. elegans""; ""Comparative Analysis of Nematode Innate Immune Systems""; ""Conclusions""; ""Acknowledgements""; ""Note Added in Proof""; ""References""; ""PART II: MODULATION OF THE IMMUNE RESPONSE: BENEFITS FOR PARASITE AND HOST"" ; ""5. Nematodes and Regulatory T cells""""Introduction""; ""Regulatory T Cells""; ""Role of Regulatory T Cells in Mouse Models of Filarial Infection""; ""Regulatory T cells in Intestinal Nematode Infections: The Case of Heligmosomoides polygyrus""; ""Tregs in Other Mouse Intestinal Nematodes""; ""Role of Tr1 and IL-10 in Nematode Infections""; ""Natural (Thymic) or Adaptive (Induced) Tregs?""; ""Evidence of Regulatory T Cells in Human Filarial Nematode Infection""; ""Tregs in Human Intestinal Nematode Infections""; ""Role of Regulatory IL-10 in Human Infections"" ; ""Induction of Regulatory T Cells""""Regulatory T Cell Therapy: The Future?""; ""Acknowledgement""; ""References""; ""6. The Alternatively Activated Macrophage""; ""Introduction""; ""Macrophages in Nematode Infection""; ""Macrophages, Th2 Immunity and Metabolism""; ""Macrophages as Effector Cells""; ""Macrophages, Tissue Repair and Homeostasis""; ""Summary""; ""Acknowledgements""; ""References""; ""7. Regulation of Immunity and Inflammation Following Intestinal Helminth Infection""; ""Introduction""; ""Gastrointestinal Nematodes"" ; ""Innate Immunity to Nematodes: New Mechanisms and Novel Cell Types""
• Sommario/riassunto: Covering a wide range of rapidly-developing fields of research into parasitic nematodes, this comprehensive volume discusses the genetics, biochemistry and immunology of nematode parasites of humans as well as domestic animals and plants. This fully-updated edition also covers new advances including horizontal gene transfer, immune expulsion mechanisms, genetics of susceptibility in humans, nematode protein structures, role of bacterial symbionts, intrinsic immune response, host immune system modulation, modulation of allergic and autoimmune diseases and the use of parasitic nematodes or their
• Titolo autorizzato: Parasitic nematodes
• ISBN: 1-78924-429-3; 1-84593-776-7
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910284953303321
• Lo trovi qui: Univ. Federico II