Modern drying technology . Volume 3 Product quality and formulation [[electronic resource] /] / edited by Evangelos Tsotsas and Arun S. Mujumdar

• Pubblicazione: Weinheim, Germany, : Wiley-VCH Verlag GmbH & Co., 2011
• Descrizione fisica: 1 online resource (432 p.)
• Disciplina: 303.625
• Soggetto topico: Drying
• Altri autori: TsotsasEvangelos MujumdarA. S
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Modern Drying Technology: Product Quality and Formulation; Contents; Series Preface; Preface of Volume 3; List of Contributors; Recommended Notation; EFCE Working Party on Drying: Address List; 1 Quality Changes in Food Materials as Influenced by Drying Processes; 1.1 Introduction; 1.2 Biochemical Reactions Induced by Drying; 1.3 Physical Transformations During Drying; 1.4 Mechanical Transformations Induced by Drying; 1.5 Storage and Rehydration of Food Products; 1.6 Conclusion; References; 2 Impact of Drying on the Mechanical Properties and Crack Formation in Rice; 2.1 Introduction ; 2.2 Impact of Drying Conditions on Head Rice Yield for Paddy and Parboiled Rice2.3 Characterization of Fissures Formation by Image Analysis Techniques; 2.4 Characterization of the Mechanical Properties of the Rice Material; 2.4.1 Stress-Strain Relationships for Linear Materials; 2.4.2 Failure Strength in Rice Grains; 2.5 Modeling the Impact of Drying on the Final Quality of Rice Grains; 2.6 Conclusion; References; 3 Characterization and Control of Physical Quality Factors During Freeze-Drying of Pharmaceuticals in Vials; 3.1 Introduction ; 3.2 Characterization Methods of the Key Quality Factors During Freeze-Drying of Pharmaceuticals in Vials3.2.1 State Diagram, Melting Curves, Vitreous Transition, Collapse Temperature; 3.2.2 Characterization Methods: DSC, MDSC, Freeze-Drying Microscopy; 3.2.3 Ice Structure and Morphology: Cold Chamber Optical Microscopy; 3.2.4 Heat Flux Heterogeneity in the Sublimation Chamber; 3.2.5 Permeability of Freeze-Drying Cake: Pressure Rise Tests; 3.2.6 Estimation of Mean Product Temperature; 3.3 Influence of Freezing and Freeze-Drying Parameters on Physical Quality Factors ; 3.3.1 Influence of Freezing Protocol on Ice Morphology3.3.1.1 Influence of Freezing Rate; 3.3.1.2 Influence of Vial Type and Filling Height; 3.3.1.3 Annealing; 3.3.2 Controlled Nucleation; 3.3.2.1 Controlled Nucleation by Ultrasound Sonication; 3.3.2.2 Effect of Ultrasound on Structural and Morphological Properties; 3.3.3 Relationship between Nucleation Temperatures and Sublimation Rates; 3.3.4 Freeze-Dried Cake Morphology; 3.3.4.1 Water Vapor Mass Transfer Resistance; 3.3.4.2 Freeze-Dried Layer Permeability; 3.3.5 Importance of Temperature Control ; 3.3.6 Influence of Operating Conditions on Sublimation Kinetics3.4 Product Quality and Stability During Drying and Storage; 3.4.1 Product Quality and Formulation; 3.4.2 Product Quality and Polymorphism; 3.5 Conclusions; References; 4 In-Line Product Quality Control of Pharmaceuticals In Freeze-Drying Processes; 4.1 Introduction; 4.2 Control of the Freezing Step; 4.3 Monitoring of the Primary Drying; 4.3.1 Monitoring of Single Vials; 4.3.2 Monitoring of a Group of Vials; 4.3.3 Monitoring of the Whole Batch; 4.3.3.1 Detection of the Endpoint of the Primary Drying ; 4.3.3.2 Monitoring the Primary Drying Using the Measurement of the Sublimation Flux
• Sommario/riassunto: This five-volume series provides a comprehensive overview of all important aspects of modern drying technology, concentrating on the transfer of cutting-edge research results to industrial use.Volume 3 deals with product quality and formulation. Biochemical, physical, and mechanical transformations which can occur during drying are described as well as methods for monitoring product quality such as process analytical technology. The preservation of desired product properties is disucssed in detail for foods and biomaterials, freeze-dried active pharmaceutical ingredients, and highly porous
• Titolo autorizzato: Modern drying technology
• ISBN: 1-283-30235-7; 9786613302359; 3-527-64399-0; 3-527-63166-6; 3-527-63167-4
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910830915303321
• Lo trovi qui: Univ. Federico II
• Serie: Modern Drying Technology