Vai al contenuto principale della pagina

Neurodegeneration : metallostasis and proteostasis / / edited by Danilo Milardi and Enrico Rizzarelli



(Visualizza in formato marc)    (Visualizza in BIBFRAME)

Titolo: Neurodegeneration : metallostasis and proteostasis / / edited by Danilo Milardi and Enrico Rizzarelli Visualizza cluster
Pubblicazione: Cambridge, : RSC Pub., 2011
Edizione: 1st ed.
Descrizione fisica: 1 online resource (285 p.)
Disciplina: 616.8047
Soggetto topico: Nervous system - Degeneration
Altri autori: MilardiDanilo  
RizzarelliEnrico  
Note generali: Description based upon print version of record.
Nota di bibliografia: Includes bibliographical references and index.
Nota di contenuto: i-iv; v-viii; xi-xiv; 1-17.PDF.pdf; 18-45; 46-68; 69-82; 83-111; 112-140; 141-151; 152-173; 174-211; 212-225; 226-248; 249-258; 259-270
Sommario/riassunto: Since Alois Alzheimer described the results of his postmortem studies in 1906, significant strides have been made in understanding the pathogenesis of neurodegenerative diseases. Substantial evidence has accumulated indicating that diverse neurodegenerative disorders might share a common pathological mechanism: the misfolding, aggregation and accumulation of proteins (termed ""amyloid"") in the brain. Metal ions have long been thought to catalyze protein misfolding initiating a cascade of events resulting in oxidative damage and neurodegeneration. They have, consequently, been seen as a suitab
Titolo autorizzato: Neurodegeneration  Visualizza cluster
ISBN: 1-84973-301-5
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910820104403321
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Serie: RSC drug discovery series ; ; 7.