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Enabling discovery, development, and translation of treatments for cognitive dysfunction in depression : workshop summary / / Lisa Bain and Clare Stroud, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy



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Titolo: Enabling discovery, development, and translation of treatments for cognitive dysfunction in depression : workshop summary / / Lisa Bain and Clare Stroud, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy Visualizza cluster
Pubblicazione: Washington, District of Columbia : , : The National Academies Press, , 2015
©2015
Descrizione fisica: 1 online resource (90 p.)
Disciplina: 616.8527
Soggetto topico: Depression, Mental - United States
Depression, Mental - Treatment - United States
Persona (resp. second.): BainLisa
StroudClare
Note generali: Description based upon print version of record.
Nota di bibliografia: Includes bibliographical references.
Nota di contenuto: FrontMatter; Reviewers; Contents; 1 Introduction and Overview; 2 The Burden of Cognitive Dysfunction in Depression; 3 State of the Science: Treatment Development; 4 Challenges and Potential Solutions to Enable Development of Successful Treatments; 5 Regulatory Issues; 6 Lessons Learned from the Schizophrenia Field; Appendix A: References; Appendix B: Workshop Agenda; Appendix C: Registered Attendees
Sommario/riassunto: "Major depressive disorder (MDD) is recognized worldwide as a major cause of disability, morbidity, and mortality. According to the World Health Organization, unipolar depressive disorders affect more than 150 million people around the world and represent the leading cause of years lost due to disability among both men and women. In the United States alone, nearly 8 percent of persons over the age of 12 report current depression. MDD has long been defined primarily as a mood disorder. However, more recently people have begun to recognize effects on cognition as a major contributor to the disablement that accompanies depression and to consider this an underrecognized treatment target for depression. To explore how best to enable the discovery, development, and translation of treatments for cognitive dysfunction in depression, including a focus on the regulatory path forward, the Institute of Medicine's Forum on Neuroscience and Nervous Disorders convened key stakeholders at a workshop in February 2015. This report summarizes the presentations from expert speakers and discussions among workshop participants"--
Titolo autorizzato: Enabling discovery, development, and translation of treatments for cognitive dysfunction in depression  Visualizza cluster
ISBN: 0-309-37396-4
0-309-37394-8
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910797749403321
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