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Multiple myeloma [[electronic resource] ] : a new era of treatment strategies / / editors, Klaus Podar, Kenneth C. Anderson



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Titolo: Multiple myeloma [[electronic resource] ] : a new era of treatment strategies / / editors, Klaus Podar, Kenneth C. Anderson Visualizza cluster
Pubblicazione: [U.S.A.], : Bentham Science Publishers, [2012]
Descrizione fisica: 1 online resource (217 p.)
Disciplina: 616.99/418
616.99418
Soggetto topico: Multiple myeloma - Treatment
Altri autori: PodarKlaus  
AndersonKenneth C  
Note generali: Description based upon print version of record.
Nota di bibliografia: Includes bibliographical references and index.
Nota di contenuto: section 1. Multiple myeloma -- section 2. Treatment guidelines -- section 3. The bone marrow microenvironment and the pathogenesis of multiple myeloma -- section 4. New treatment strategies.
Sommario/riassunto: Multiple Myeloma (MM), the second most common blood cancer in adults, is a clonal plasma cell malignancy within the bone marrow characterized by osteolytic bone lesions, renal disease, and immunodeficiency. It is now well established that MM cell- induced disruption of the bone marrow homeostasis between the highly organized cellular and extracellular compartments supports MM cell proliferation, survival, migration, and drug resistance via activation of various signaling pathways. Based on this knowledge, the prototypic drugs thalidomide, bortezomib, and lenalidomide, which target both MM cell
Titolo autorizzato: Multiple myeloma  Visualizza cluster
ISBN: 1-60805-297-4
Formato: Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione: Inglese
Record Nr.: 9910790451003321
Lo trovi qui: Univ. Federico II
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