Chemokines [[electronic resource] ] : types, functions, and structural characteristics / / Keith J. Walker, editor

• Pubblicazione: New York, : Nova Science Publishers, c2011
• Descrizione fisica: 1 online resource (197 p.)
• Disciplina: 616.07/9
• Soggetto topico: Chemokines; Immunology
• Altri autori: WalkerKeith J
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: ""CHEMOKINES: TYPES, FUNCTIONS AND STRUCTURAL CHARACTERISTICS ""; ""CHEMOKINES: TYPES, FUNCTIONS AND STRUCTURAL CHARACTERISTICS ""; ""Contents ""; ""Preface""; ""Mechanisms and Development of Chemokine Network Targeting Agents for the Treatment of Allergic, Autoimmune and Inflammatory Diseases and Cancers ""; ""Abstract ""; ""Introduction ""; ""The Question of Redundancy ""; ""Selection of Chemokine Targets""; ""Chemokine Receptor Antagonism ""; ""Current Status ""; ""Biology of GAGs in Chemokine Biology and Leukocyte Trafficking ""; ""Glycosaminoglycan Structure, Function and Diversity "" ; ""Specificity in Chemokine-GAG Interactions and GAG-Induced Oligomerization """"Chemokine Oligomerization Controls Cell Surface Presentation ""; ""Non-GAG Binding and Improved GAG Binding Chemokine Mutants ""; ""Double Negative Knockout Chemokine Mutants with Improved GAG Affinity and Ablated Chemokine Receptor Binding Potential""; ""Other Novel Therapeutic Approaches ""; ""Broad-Spectrum Chemokine Inhibitors (BCSIs) ""; ""Spiegelmers ""; ""Bindarit ""; ""Chemokine-Targeted Cell Depleting Agents ""; ""Chemokines and Gene Therapy""; ""Gene Therapy Vectors and Delivery "" ; ""Direct Gene Delivery in vivo """"Immune Effector Cell Recruitment ""; ""Regulation of Angiogenesis ""; ""Inhibition of Endogenous Chemokine Ligands ""; ""Stem Cell Therapy ""; ""RNA Interference ""; ""Background ""; ""RNAi Developmental Hurdles ""; ""RNAi Studies in Cancer and Metastasis ""; ""RNAi Studies in Viral Infection ""; ""RNAi Studies in Inflammatory Diseases""; ""Conclusion ""; ""Acknowledgments ""; ""References ""; ""How Chemokines Implicate in T Lymphocyte Biology ""; ""Abstract ""; ""Introduction "" ; ""The Role of Chemokines and Chemokine Receptors on Gamma Delta Development in the Thymus """"Chemokine Guidance of Tissue-Specific Homing and Recirculation of T Lymphocytes ""; ""Migration of T Lymphocytes into Tissue during Inflammation""; ""Chemokine Receptors as Markers of T Lymphocyte Phenotype ""; ""Production of Chemokines by T Lymphocytes in Inflammation & Infection ""; ""Concluding Remarks ""; ""Footnote ""; ""References ""; ""Chemokines in Teleost Fish Species""; ""Abstract ""; ""Introduction ""; ""Zebrafish Chemokines""; ""Rainbow Trout Chemokines "" ; ""Catfish Chemokines """"Chemokines in Other Fish Species ""; ""Chemokine Receptors ""; ""Conclusion ""; ""Acknowledgments ""; ""References""; ""Gene Regulation and Expression of Chemokines in Response to Bacterial Enterotoxins ""; ""Abstract ""; ""Introduction ""; ""B. Fragilis Enterotoxin Stimulation Up-Regulates Cxc Chemokines in Intestinal Epithelial Cells ""; ""C. Difficile Enterotoxin (Toxin A) Up-Regulates CXC and CC Chemokines in Intestinal Epithelial Cells "" ; ""NF- B Activation Pathway in Intestinal Epithelial cells is a Major Regulator of Chemokine Gene Expression in Intestinal Epithelial cells Stimulated With B. Fragilis Enterotoxin and C. Difficile Toxin A ""
• Titolo autorizzato: Chemokines
• ISBN: 1-61761-171-9
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910824149603321
• Lo trovi qui: Univ. Federico II
• Serie: Cell Biology Research Progress