Practical transfusion medicine / / edited by Michael F. Murphy, [and three others]

• Pubblicazione: Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2022]; ©2022
• Edizione: 6th ed.
• Descrizione fisica: 1 online resource (673 pages)
• Disciplina: 615.39
• Soggetto topico: Blood - Collection and preservation
• Persona (resp. second.): MurphyMichael F (Michael Furber)
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Cover -- Title Page -- Copyright Page -- Contents -- List of Contributors -- Preface to the Sixth Edition -- Chapter 1 Introduction: Two Centuries of Progress in Transfusion Medicine -- Blood Donation Worldwide -- Changing Landscape of Transfusion Risks -- Immunohaematology -- Clinical Use of Blood Components: Evolution Based on Evidence -- Urgent Transfusion -- Patients Requiring Chronic Transfusion Support -- Obstetric, Neonatal and Paediatric Transfusion Medicine -- Haemostasis and Transfusion -- Cellular Therapies, Transplantation, Apheresis -- The Future -- Conclusion -- References -- Chapter 2 Essential Immunology for Transfusion Medicine -- Cellular Basis of the Immune Response -- Innate Immune Cells -- Adaptive Immune Cells -- B-Cell Activation and T-Cell-Dependent Antibody Formation -- Humoral Immune Response -- Basis of Antibody Variability -- Antibody Effector Functions -- Red Blood Cell Antibodies Illustrating These Principles -- Antibody and Complement-Mediated Blood Cell Destruction -- Clinical Aspects Related to Alloimmunisation against Blood Cell Antigens -- Acknowledgement -- References -- Further Reading -- Chapter 3 Human Blood Group Systems -- The ABO System -- Clinical Significance -- Biosynthesis and Molecular Genetics -- H, the Biochemical Precursor of A and B -- The Rh System -- Rh Genes and Proteins -- D Antigen -- Anti-D -- Prediction of Fetal Rh Phenotype by Molecular Methods -- C and c, E and e -- Other Rh Antigens -- Other Blood Group Systems -- Kell System -- Duffy System -- Kidd System -- MNS System -- Biological and Clinical Significance of Blood Group Antigens -- References -- Further Reading -- Chapter 4 Human Leukocyte Antigens -- HLA Class I Genes -- HLA Class II Genes -- Genetic Organisation and Expression of HLA Class II Genes -- Expression of HLA Molecules -- Genetics -- Function of HLA Molecules. ; HLA Nomenclature, Gene Polymorphism and Molecular HLA Typing -- PCR Sequence-Specific Priming -- PCR Sequence-Specific Oligonucleotide Probing -- DNA Sequencing-Based Typing -- Formation of HLA Antibodies -- HLA Antibody Detection -- CDC/Microlymphocytotoxicity Assay -- Solid-Phase Antibody Detection Assays -- Crossmatching for Compatibility Evaluation -- Physical Crossmatches -- Virtual Crossmatches -- HLA and Solid Organ Transplantation -- HLA and Haematopoietic Stem Cell Transplantation -- HLA and Blood Transfusion -- HLA and Disease Association -- HLA and Pharmacogenomics -- Acknowledgements -- References -- Further Reading -- Chapter 5 Platelet and Neutrophil Antigens -- Antigens on Platelets and Neutrophils -- Human Platelet Antigens -- Inheritance and Nomenclature -- Typing for HPAs -- Platelet Isoantigens, Autoantigens and Drug-Dependent Antigens -- Detection of HPA Alloantibodies -- Clinical Significance of HPA Alloantibodies -- Fetal and Neonatal Alloimmune Thrombocytopenia -- Human Neutrophil Antigens -- HNA-1 -- HNA-2 -- HNA-3 -- HNA-4 and HNA-5 -- Detection of Neutrophil Antibodies -- Clinical Significance of HNA Antibodies -- Neonatal Alloimmune Neutropenia -- FNHTR and TRALI -- Autoimmune Neutropenia -- Persistent Post-Bone Marrow Transplant Neutropenia -- Drug-Induced Neutropenia -- References -- Further Reading -- Chapter 6 Pretransfusion Testing and the Selection of Red Cell Products for Transfusion -- Determining the Recipient's ABO Group and Screening for Unexpected Antibodies -- Clerical Check and Verification of Recipient's Identity -- Determining the Recipient's ABO Group -- Determining the Recipient's D Type -- Difficulties in D Typing: Weak and Partial D -- Antibody Screening and Identification -- Antibody Detection Methods -- Liquid-Phase ('Tube') Systems -- Column-Agglutination Systems -- Solid-Phase Systems. ; Autoantibodies -- Pretransfusion Molecular Testing -- Crossmatching Techniques -- Crossmatch Techniques for Patients without Current or Historical Antibodies -- Crossmatch Techniques for Patients with Current or Historical Antibodies -- Selection of Red Cells for Transfusion -- Selecting ABO-Compatible Red Cells -- Selecting D-Compatible Red Cells -- Clinical Significance of Unexpected Antibodies -- Use of Uncrossmatched Red Cells -- Selection of Platelets and Plasma Components -- References -- Further Reading -- Chapter 7 Investigation of Acute Transfusion Reactions -- Understanding the Clinical Presentation and Differential Diagnosis -- Patient History -- Medications -- Type of Blood Component Being Transfused -- Was Fever Present? -- Volume of Component Transfused -- Other Considerations -- General Approach for Investigation and Treatment of Acute Transfusion Reactions -- Action to Be Taken on the Clinical Unit -- Action to Be Taken in the Laboratory -- Algorithm -- References -- Further Reading -- Chapter 8 Haemolytic Transfusion Reactions -- Definition of a Haemolytic Transfusion Reaction -- Pathophysiology of Haemolytic Transfusion Reactions -- Antibody-Mediated haemolysis -- Antigen-Antibody Interactions -- Characteristics of the Antibody and Antigen -- Complement Activation -- Fc Receptor Interactions -- Cytokines -- Antibody Specificities Associated with Haemolytic Transfusion Reactions -- The Pathophysiology of Hyperhaemolysis (aka Post-Transfusion Haemophagocytic Syndrome) -- Acute Haemolytic Transfusion Reactions -- Aetiology and Incidence -- Symptoms and Signs -- Complications -- Immediate Management of Suspected Acute Haemolytic Transfusion Reactions -- Investigation of Suspected Acute Haemolytic Transfusion Reactions -- Other Reactions Characterised by Haemolysis -- Management of a Confirmed Acute Haemolytic Transfusion Reaction. ; Prevention of Acute Haemolytic Transfusion Reactions -- Delayed Haemolytic Transfusion Reactions -- Aetiology and Incidence -- Signs and Symptoms -- Management -- Investigation of Suspected Delayed Haemolytic Transfusion Reactions (see Chapter 7) -- Prevention -- Haemolysis Resulting from Haemopoietic Stem Cell Transplantation (see Chapter 41) -- Delayed Haemolysis Following Organ Transplantation (Passenger Lymphocyte Syndrome) -- Haemophagocytic/Hyperhaemolytic Transfusion Reactions and Haemolytic Transfusion Reactions in Sickle Cell Disease -- Acute Haemolysis from ABO-Incompatible Platelet Transfusions -- References -- Further Reading -- Chapter 9 Febrile and Allergic Transfusion Reactions -- Febrile Non-haemolytic Transfusion Reactions -- Clinical Presentation -- Differential Diagnosis -- Frequency -- Pathogenesis -- Management of Febrile Non-haemolytic Transfusion Reactions -- Prevention of Febrile Non-haemolytic Transfusion Reactions -- Allergic Transfusion Reactions -- Clinical Presentation -- Differential Diagnosis -- Frequency -- Pathogenesis -- Management -- Prevention -- References -- Further Reading -- Chapter 10 Transfusion-Associated Circulatory Overload -- Definition -- Incidence and Outcomes -- Clinical Manifestations -- Pathophysiology -- Risk Factors -- Extremes of Age -- Fluid Balance -- Renal and Cardiac Dysfunction -- Transfusion Volume and Rate -- Type of Product -- Differential Diagnosis and Evaluation -- Patient Characteristics and Onset of Symptoms -- Symptoms -- Laboratory Assessment -- Radiological Evaluation -- Echocardiography -- Invasive Measurements -- Treatment and Prevention -- References -- Further Reading -- Chapter 11 Transfusion-Related Acute Lung Injury (TRALI) -- Definition -- Incidence, Outcomes and Recipient Risk Factors -- Clinical Manifestations -- Differential Diagnosis -- Pathogenesis -- Two-Hit Model. ; Susceptibility Hit and Potential Role for Perioperative Third Hit -- Immune Cell Involvement -- Potential Therapeutic Avenues -- Mitigation Strategies -- Patient Management -- Reporting -- References -- Further Reading -- Chapter 12 Purported Adverse Effects of 'Old Blood' -- Randomised Controlled Trials of Red Blood Cell Storage Duration -- Recent Randomised Controlled Trials of Red Blood Cell Storage Duration in Children -- Recent Randomised Controlled Trials of Red Blood Cell Storage Duration in Adults -- Systematic Reviews and Secondary Analyses of Randomised Controlled Trials of Red Blood Cell Storage Duration -- Future Research -- Conclusions -- References -- Further Reading -- Chapter 13 Transfusion-Induced Immunomodulation -- Mitigation of Immunomodulation after Red Cell Transfusion -- Leucocyte-Reduced Allogeneic Red Cell Transfusions Reduce Mortality in Cardiac Surgery -- Observational and Cohort Studies of Transfusion Immunomodulation Link Red Cell Transfusions to Both Beneficial and Adverse Outcomes -- Duration of Red Cell Storage and Immunomodulation -- Experimental Studies and Transfusion Immunomodulation -- Conclusion -- References -- Further Reading -- Chapter 14 Transfusion-Associated Graft-versus-Host Disease and Microchimerism -- Transfusion-Associated Graft-versus-Host Disease -- Pathogenesis -- Clinical Features -- Prevention -- Blood Component Factors -- Patients at Increased Risk -- Guidelines and Requirements for Irradiated Products -- Universal Irradiation -- Pathogen Inactivation -- Haemovigilance -- Transfusion-Associated Microchimerism -- Clinical Data -- References -- Further Reading -- Chapter 15 Posttransfusion Purpura -- Definition -- Incidence -- Clinical Features -- Differential Diagnosis -- Laboratory Investigations -- Pathophysiology -- Management -- Prevention of Recurrence of Posttransfusion Purpura -- References. ; Further Reading.
• Sommario/riassunto: "The primary purpose of this edition remains the same as the first, namely to provide a comprehensive guide to transfusion medicine. The book aims to include information in more depth than is contained within handbooks of transfusion medicine, and yet to present that information in a more concise and approachable manner than is seen in large, standard reference texts. The feedback we have received not only from formal and informal reviews but also from colleagues is that these objectives continue to be achieved, and that the book benefits from a consistent style and format for its chapters. We have again striven to maintain this standard in the sixth edition and to provide a text that will be useful to clinical and scientific staff, both established practitioners and trainees, who are involved in transfusion medicine and require an accessible text. The book is divided into seven sections, which systematically take the reader through the principles of transfusion medicine, the complications of transfusion, practice in blood centres and hospitals, clinical transfusion practice, a new section on patient blood management, cellular and tissue therapy and organ transplantation and the development of the evidence base for transfusion. The main changes from the fifth edition are a new chapter on transfusion-associated circulatory overload by Alexander Vlaar to underline the condition's importance as a complication of transfusion, and a reconfiguration of the section on clinical transfusion practice to consider the transfusion management of medical, surgical and haematology patients with and without bleeding. The number of chapters has therefore been increased from 49 to 51. The first and final chapters on the recent evolution of transfusion medicine and scanning the future of transfusion medicine have always generated much interest in previous editions, and we are very grateful that Sunny Dzik, Ed Snyder, Paul Ness and Jay Menitove have provided excellent updates of their respective reviews for this edition"--
• Titolo autorizzato: Practical transfusion medicine
• ISBN: 1-119-66588-4; 1-119-66578-7; 1-119-66583-3
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Lingua di pubblicazione: Inglese
• Record Nr.: 9910677631803321
• Lo trovi qui: Univ. Federico II